The gene/protein map for NC_008254 is currently unavailable.
Definition Mesorhizobium sp. BNC1, complete genome.
Accession NC_008254
Length 4,412,446

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The map label for this gene is kduD [H]

Identifier: 110632621

GI number: 110632621

Start: 300195

End: 300953

Strand: Reverse

Name: kduD [H]

Synonym: Meso_0260

Alternate gene names: 110632621

Gene position: 300953-300195 (Counterclockwise)

Preceding gene: 110632622

Following gene: 110632620

Centisome position: 6.82

GC content: 65.48

Gene sequence:

>759_bases
ATGACCTCCACCTTCAGCCTCGAAAGCCGGAGGATCATGGTTACGGGTGCCAATACGGGCATCGGCCAGGGCATCGCCGT
GGCCGCAGCGCGCGCCGGAGCCGAAGTACTGGGCGTCGGCCGTTCGTCCATGGACGAGAGCGAGAAGCTCGTGGAGGCGC
AGGGGACCAGCTTCACCGCGATTTCGTGCGACCTAGCAGATCCGGCCGCCTCCAGCGCCATGTTCGATCGGGCTTGGGAG
GAACATGGGCCCATCGACGGGCTCGTCAACAATGCCGGCATCATCCGCCGAGTGGATGCCGTCGACCTCACCGAGGCCGA
CTGGGACGACGTGATGGACATTAATCTCAAGACGCTCTTCACGCTCTGCCAAGCCTTCGGCCGCAAGCTGATTGCCGGCG
GGCGGCGTGGCAAAATCGTCAACGTCGCCTCGGTGCTTTCCTTTCAGGGCGGGATACGCGTTGCCTCCTACACGGCTTCC
AAACACGGGGTGCTGGGTTTGACGCGGGTGCTGGCCTGCGAGTGGGCGGGAAAAGGCATTAACGTCAACGCCGTGGCGCC
CGGCTATATCGAGACGAACAACACCGAGGCCCTGCGCAACGACCCGGACCGCAGCGACTCAATCCTTGCGCGCATCCCGG
CCGGGCGCTGGGGCCGCCCCGAGGACATCGGCGACGCGGCCGTTTTCCTGCTCGCGCCCGCCTCGGACTATATGCATGGT
GCCGTTATCCCCGTCGATGGCGGCTGGCTCGCACGCTAG

Upstream 100 bases:

>100_bases
TCCATTCGGGTTGCGGCAGGGCAGTTATGCCTCTATCTGGGCGACTGTCGGCGATTAGTCACTACACGGATGCCGGCCGG
GTACTACGGGAGACAATGCG

Downstream 100 bases:

>100_bases
GCAAACCAAACGGCCGAGGCGAATTCTTCAGGCGGAAAATGAGGGCGAGGAGACCACCTTTTTTGCGGGCGGTTCCTCCA
TCGTGCCGTCCCAAAACCGT

Product: 2-deoxy-D-gluconate 3-dehydrogenase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTSTFSLESRRIMVTGANTGIGQGIAVAAARAGAEVLGVGRSSMDESEKLVEAQGTSFTAISCDLADPAASSAMFDRAWE
EHGPIDGLVNNAGIIRRVDAVDLTEADWDDVMDINLKTLFTLCQAFGRKLIAGGRRGKIVNVASVLSFQGGIRVASYTAS
KHGVLGLTRVLACEWAGKGINVNAVAPGYIETNNTEALRNDPDRSDSILARIPAGRWGRPEDIGDAAVFLLAPASDYMHG
AVIPVDGGWLAR

Sequences:

>Translated_252_residues
MTSTFSLESRRIMVTGANTGIGQGIAVAAARAGAEVLGVGRSSMDESEKLVEAQGTSFTAISCDLADPAASSAMFDRAWE
EHGPIDGLVNNAGIIRRVDAVDLTEADWDDVMDINLKTLFTLCQAFGRKLIAGGRRGKIVNVASVLSFQGGIRVASYTAS
KHGVLGLTRVLACEWAGKGINVNAVAPGYIETNNTEALRNDPDRSDSILARIPAGRWGRPEDIGDAAVFLLAPASDYMHG
AVIPVDGGWLAR
>Mature_251_residues
TSTFSLESRRIMVTGANTGIGQGIAVAAARAGAEVLGVGRSSMDESEKLVEAQGTSFTAISCDLADPAASSAMFDRAWEE
HGPIDGLVNNAGIIRRVDAVDLTEADWDDVMDINLKTLFTLCQAFGRKLIAGGRRGKIVNVASVLSFQGGIRVASYTASK
HGVLGLTRVLACEWAGKGINVNAVAPGYIETNNTEALRNDPDRSDSILARIPAGRWGRPEDIGDAAVFLLAPASDYMHGA
VIPVDGGWLAR

Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=34.6938775510204, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=32.9411764705882, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=31.3725490196078, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=33.8983050847458, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=30.8, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=30.327868852459, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=30.3149606299213, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=31.4741035856574, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=32.1428571428571, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=28.2945736434109, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI31542939, Length=210, Percent_Identity=30.4761904761905, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4503301, Length=204, Percent_Identity=26.9607843137255, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI109715829, Length=238, Percent_Identity=26.4705882352941, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4504505, Length=196, Percent_Identity=29.5918367346939, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI59889578, Length=206, Percent_Identity=29.6116504854369, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=30.3191489361702, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI4758504, Length=183, Percent_Identity=31.1475409836066, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI224922801, Length=179, Percent_Identity=31.8435754189944, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=31.4432989690722, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI40807363, Length=191, Percent_Identity=27.7486910994764, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=53.968253968254, Blast_Score=272, Evalue=2e-74,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=37.6, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=35.5102040816327, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=35.5731225296443, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=36.5758754863813, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=29.5081967213115, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=32.7868852459016, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=32.6693227091633, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=30.5220883534137, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=30.2788844621514, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=30.241935483871, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789057, Length=181, Percent_Identity=27.6243093922652, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787526, Length=190, Percent_Identity=30.5263157894737, Blast_Score=67, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=34.0080971659919, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=30.1204819277108, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=32.2448979591837, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=28.9156626506024, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=33.0677290836653, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=30.2040816326531, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=254, Percent_Identity=32.6771653543307, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17561272, Length=233, Percent_Identity=30.4721030042918, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=29.6153846153846, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=28.1746031746032, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=254, Percent_Identity=30.7086614173228, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=29.7709923664122, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=29.2490118577075, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=30.7984790874525, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=29.4339622641509, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=29.9625468164794, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=29.6992481203008, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=27.6, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=254, Percent_Identity=31.1023622047244, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=28.6274509803922, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=29.1828793774319, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=255, Percent_Identity=28.6274509803922, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=27.4509803921569, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=254, Percent_Identity=27.1653543307087, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=255, Percent_Identity=28.6274509803922, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=28.6458333333333, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=255, Percent_Identity=27.0588235294118, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=256, Percent_Identity=27.734375, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=26.530612244898, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=187, Percent_Identity=27.807486631016, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=187, Percent_Identity=27.807486631016, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71997099, Length=206, Percent_Identity=27.6699029126214, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=197, Percent_Identity=28.9340101522843, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=200, Percent_Identity=29, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=258, Percent_Identity=26.7441860465116, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=31.1224489795918, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6324126, Length=174, Percent_Identity=31.0344827586207, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=34.4262295081967, Blast_Score=131, Evalue=5e-31,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=31.8725099601594, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24643142, Length=243, Percent_Identity=32.5102880658436, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=32.4110671936759, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21355319, Length=243, Percent_Identity=29.2181069958848, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=32.1428571428571, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=31.0756972111554, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=29.1828793774319, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24644337, Length=193, Percent_Identity=30.5699481865285, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641232, Length=251, Percent_Identity=29.0836653386454, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=31.3131313131313, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357673, Length=249, Percent_Identity=28.1124497991968, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI18859837, Length=191, Percent_Identity=29.3193717277487, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011286
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.127 [H]

Molecular weight: Translated: 26545; Mature: 26414

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTSTFSLESRRIMVTGANTGIGQGIAVAAARAGAEVLGVGRSSMDESEKLVEAQGTSFTA
CCCCEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEECCCCCCCHHHHHHHHCCCEEEE
ISCDLADPAASSAMFDRAWEEHGPIDGLVNNAGIIRRVDAVDLTEADWDDVMDINLKTLF
EEECCCCCCHHHHHHHHHHHHCCCCCHHCCCCCEEEEECCCCCCCCCCCCEEECCHHHHH
TLCQAFGRKLIAGGRRGKIVNVASVLSFQGGIRVASYTASKHGVLGLTRVLACEWAGKGI
HHHHHHHHHHHCCCCCCCEEEHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCE
NVNAVAPGYIETNNTEALRNDPDRSDSILARIPAGRWGRPEDIGDAAVFLLAPASDYMHG
EEEEECCCEEECCCCHHHCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCHHCCC
AVIPVDGGWLAR
EEEEECCCCCCC
>Mature Secondary Structure 
TSTFSLESRRIMVTGANTGIGQGIAVAAARAGAEVLGVGRSSMDESEKLVEAQGTSFTA
CCCEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEECCCCCCCHHHHHHHHCCCEEEE
ISCDLADPAASSAMFDRAWEEHGPIDGLVNNAGIIRRVDAVDLTEADWDDVMDINLKTLF
EEECCCCCCHHHHHHHHHHHHCCCCCHHCCCCCEEEEECCCCCCCCCCCCEEECCHHHHH
TLCQAFGRKLIAGGRRGKIVNVASVLSFQGGIRVASYTASKHGVLGLTRVLACEWAGKGI
HHHHHHHHHHHCCCCCCCEEEHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCE
NVNAVAPGYIETNNTEALRNDPDRSDSILARIPAGRWGRPEDIGDAAVFLLAPASDYMHG
EEEEECCCEEECCCCHHHCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEECCCHHCCC
AVIPVDGGWLAR
EEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766386 [H]