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The map label for this gene is degP [H]

Identifier: 110632608

GI number: 110632608

Start: 279045

End: 279662

Strand: Direct

Name: degP [H]

Synonym: Meso_0247

Alternate gene names: 110632608

Gene position: 279045-279662 (Clockwise)

Preceding gene: 110632607

Following gene: 110632609

Centisome position: 6.32

GC content: 61.0

Gene sequence:

>618_bases
ATGAGGACTCTGTTTGTCGTGGTGGCCTTCGCTGCCGCGCTTCTCACCGCGTGCTCATTCTCCAGACAACCCGCCATGGC
TGATTCCGTGGTGAAGATCATCGTTGGCGCAGGCCACGGCTCAGGCGTTCACATCGGGGACGGCTATATCATCAGCGCAT
CCCATGTGGTGGGTACTGCCGAGAAGGTTGAGCTAAAGACATCATCCGGGGGCGAGGCCGAAGCAGTCGTGCTGTGGGCC
AACAAGGCTTACGACATCGCGCTCTTGCGTGTCTCGGATCGGTCTGGGTTAGGAATGTCCCGGCTCGCCTGCACCGTCCC
TTCCGTGGGCGATGAGGTGATTGCCAAGGGCAACCCCATCAATGCCGAGTTCATCACTGTGTGGGGCCGCATAGCCGATT
CCGTCCGTGAGGCTGGGCCGTGGAAGTCCGTGGTTATAACGGACATTGCAACAGTGCCGGGTCAGAGCGGCGGCGGTGTT
TTCGACACCCAAGGGCGTCTAATCGGAATCACCGTTGGCGTCATGGTCGCGCCGGTTGGTTTCTCGGCCTCGCTGGTGGG
TGTGGGCTACGTTGTACCAGGCCGCGTTGTTTGTGACCTCCTTGCGCGGGGTGCCTGA

Upstream 100 bases:

>100_bases
CCATTCTGTCCGCACTGACATCAAGAGCCTGAACGACCGCATAGACCGGCTCTTTGAAAATCCTCCCAAGCGTACCCGTT
CAACATCATAGGAGGCCCGC

Downstream 100 bases:

>100_bases
TGAAAATCCCCTCTCTCGATGATGAGACGATCCAGAAGATCATCCAGACCTATAGGGAGACAGGAAATTTCAGAGAGACA
GGCAGGATTCACGGCGTAGC

Product: serine protease DO-like precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MRTLFVVVAFAAALLTACSFSRQPAMADSVVKIIVGAGHGSGVHIGDGYIISASHVVGTAEKVELKTSSGGEAEAVVLWA
NKAYDIALLRVSDRSGLGMSRLACTVPSVGDEVIAKGNPINAEFITVWGRIADSVREAGPWKSVVITDIATVPGQSGGGV
FDTQGRLIGITVGVMVAPVGFSASLVGVGYVVPGRVVCDLLARGA

Sequences:

>Translated_205_residues
MRTLFVVVAFAAALLTACSFSRQPAMADSVVKIIVGAGHGSGVHIGDGYIISASHVVGTAEKVELKTSSGGEAEAVVLWA
NKAYDIALLRVSDRSGLGMSRLACTVPSVGDEVIAKGNPINAEFITVWGRIADSVREAGPWKSVVITDIATVPGQSGGGV
FDTQGRLIGITVGVMVAPVGFSASLVGVGYVVPGRVVCDLLARGA
>Mature_205_residues
MRTLFVVVAFAAALLTACSFSRQPAMADSVVKIIVGAGHGSGVHIGDGYIISASHVVGTAEKVELKTSSGGEAEAVVLWA
NKAYDIALLRVSDRSGLGMSRLACTVPSVGDEVIAKGNPINAEFITVWGRIADSVREAGPWKSVVITDIATVPGQSGGGV
FDTQGRLIGITVGVMVAPVGFSASLVGVGYVVPGRVVCDLLARGA

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Escherichia coli, GI1789629, Length=182, Percent_Identity=27.4725274725275, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786356, Length=173, Percent_Identity=29.4797687861272, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 20908; Mature: 20908

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLFVVVAFAAALLTACSFSRQPAMADSVVKIIVGAGHGSGVHIGDGYIISASHVVGTA
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEEEEECCCCCCEEECCCEEEECCHHCCCC
EKVELKTSSGGEAEAVVLWANKAYDIALLRVSDRSGLGMSRLACTVPSVGDEVIAKGNPI
CEEEEEECCCCCEEEEEEEECCCEEEEEEEECCCCCCCHHHHEEECCCCCCHHEECCCCC
NAEFITVWGRIADSVREAGPWKSVVITDIATVPGQSGGGVFDTQGRLIGITVGVMVAPVG
CCCEEEHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEECCCEEEEEEEEEEEECCC
FSASLVGVGYVVPGRVVCDLLARGA
CCEEEEEEEEECCHHHHHHHHHCCC
>Mature Secondary Structure
MRTLFVVVAFAAALLTACSFSRQPAMADSVVKIIVGAGHGSGVHIGDGYIISASHVVGTA
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEEEEECCCCCCEEECCCEEEECCHHCCCC
EKVELKTSSGGEAEAVVLWANKAYDIALLRVSDRSGLGMSRLACTVPSVGDEVIAKGNPI
CEEEEEECCCCCEEEEEEEECCCEEEEEEEECCCCCCCHHHHEEECCCCCCHHEECCCCC
NAEFITVWGRIADSVREAGPWKSVVITDIATVPGQSGGGVFDTQGRLIGITVGVMVAPVG
CCCEEEHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEECCCEEEEEEEEEEEECCC
FSASLVGVGYVVPGRVVCDLLARGA
CCEEEEEEEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]