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The map label for this gene is dcuA [H]

Identifier: 109947493

GI number: 109947493

Start: 826296

End: 827624

Strand: Reverse

Name: dcuA [H]

Synonym: Hac_0947

Alternate gene names: 109947493

Gene position: 827624-826296 (Counterclockwise)

Preceding gene: 109947495

Following gene: 109947492

Centisome position: 53.26

GC content: 43.49

Gene sequence:

>1329_bases
ATGGATACCTTTTTTCAAATTATCGTGTTACTTTTTTCGCTTTTTTTAGGGGCAAGGCTAGGGGGTTTGGGGGTGGGCTA
TGTGGGGGGCTTGGGAGTGTTTGTTTTGTGCTTGTTTTTAGGGCTAAATCCGGGCAAAATCCCCTTTGATGTGATTTTAA
TCATCATGGCAGTCATTAGCGCTATTAGCGCGATGCAAAAGGCTGGAGGGTTAGATTATTTAGTCAAAATCGCTGAAAGA
ATTTTAAGAAAACACCCCAAGCAAATCAACTATTTAGCGCCTAGCGTGGCGTATTTTTTAACGATACTAGCGGGCACTGG
GCATACGGTTTTTTCTTTGATCCCAGTGATTGTAGAGGTGAGTCAAAGCCAAAACATCAAACCCAAAGTGCCGTTGAGTT
TAGCGGTCGTCTCTAGTCAGGTGGGCATTACTGCAAGCCCAGTGAGCGCGGCGGTGGTGTTTATGAGTGGTATTTTAGAG
CCTTTGGGGGCAAATTACTTAACTCTTTTAATGATCTGGATCCCTACGACTTTTTTAGCATGCATGTTCACGGCGTTTAT
TATGGGTTTTACCAATTTAAAGTTAGACAGCGATCCCAACTATTTAGAGCGCTTGAAAATGGGCAAAATTTCGCCTCCTA
AAATCAAAGAAGAAAAAGAAGTTTCAAAAAACGCGAAATTATCGTTATGGATTTTTATTGGTGGGGTTGTGGCGATCGTT
TTTTATGCGAGTGCGATTTCTAAAAATATCGCTTTAATTAGCCCGGTGATTTTAGGAAGAGATCAAGCGATCGTGTCTTT
CATGCTAAGCGTGGCGGCTTTAATTGCGATTTTTTGTAAAATCAATGCCAATGAAATCGCCCATTCAAGCGTGTTTAAAT
CCGGCATGCAAGCGTGCGTGTGCGTGCTGGGAGTGGCGTGGTTAGGCGATACTTTTGTGAGCAATCATTTAAATGAAATC
GAGCGCTACGCTTCTTTTTTGATCGCAGATTATCCGTTTTTATTGGCTGTGGCGCTCTTTTTTGCTTCTATGCTTTTGTA
TTCGCAAGCTGCCACTTCTAAAGCGCTCATCCCAAGCGTGATCATAGCTTTAGGCATTGGTGCTAATCACACGGAGCATT
TGTATATTATCGTGGCTTCTTTTGCAAGCGTTTCAGCGCTATTTGTGTTACCCACTTACCCCACTTTGCTAGGAGCGATC
GCTATGGATAACACCGGCACCACCAAAATGGGCCGTTATGTGTTTGATCATGCGTTTTTGATCCCTGGGGTTTTAGTCGT
GGCTTTGAGCGTGGCGTTAGGGTTTGTTGTCGCACCGTTGGTTTTGTAG

Upstream 100 bases:

>100_bases
TAAATTTCAAAAACATTCTCATTATAGACCACCTTTTGAAATTTAAAAGATTTTGTAGTATAGTAAAACATCGTTAAAAT
AAATTTAAAAAGGGTTAATG

Downstream 100 bases:

>100_bases
TTTTTATTATGATTTTTATAATTTAATATTTTATAAAAACTCCAAAAAACTTTTTTTGAAACGCAAAAATATTATTTTGC
TTGAAAATTCAATAAATTTA

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MDTFFQIIVLLFSLFLGARLGGLGVGYVGGLGVFVLCLFLGLNPGKIPFDVILIIMAVISAISAMQKAGGLDYLVKIAER
ILRKHPKQINYLAPSVAYFLTILAGTGHTVFSLIPVIVEVSQSQNIKPKVPLSLAVVSSQVGITASPVSAAVVFMSGILE
PLGANYLTLLMIWIPTTFLACMFTAFIMGFTNLKLDSDPNYLERLKMGKISPPKIKEEKEVSKNAKLSLWIFIGGVVAIV
FYASAISKNIALISPVILGRDQAIVSFMLSVAALIAIFCKINANEIAHSSVFKSGMQACVCVLGVAWLGDTFVSNHLNEI
ERYASFLIADYPFLLAVALFFASMLLYSQAATSKALIPSVIIALGIGANHTEHLYIIVASFASVSALFVLPTYPTLLGAI
AMDNTGTTKMGRYVFDHAFLIPGVLVVALSVALGFVVAPLVL

Sequences:

>Translated_442_residues
MDTFFQIIVLLFSLFLGARLGGLGVGYVGGLGVFVLCLFLGLNPGKIPFDVILIIMAVISAISAMQKAGGLDYLVKIAER
ILRKHPKQINYLAPSVAYFLTILAGTGHTVFSLIPVIVEVSQSQNIKPKVPLSLAVVSSQVGITASPVSAAVVFMSGILE
PLGANYLTLLMIWIPTTFLACMFTAFIMGFTNLKLDSDPNYLERLKMGKISPPKIKEEKEVSKNAKLSLWIFIGGVVAIV
FYASAISKNIALISPVILGRDQAIVSFMLSVAALIAIFCKINANEIAHSSVFKSGMQACVCVLGVAWLGDTFVSNHLNEI
ERYASFLIADYPFLLAVALFFASMLLYSQAATSKALIPSVIIALGIGANHTEHLYIIVASFASVSALFVLPTYPTLLGAI
AMDNTGTTKMGRYVFDHAFLIPGVLVVALSVALGFVVAPLVL
>Mature_442_residues
MDTFFQIIVLLFSLFLGARLGGLGVGYVGGLGVFVLCLFLGLNPGKIPFDVILIIMAVISAISAMQKAGGLDYLVKIAER
ILRKHPKQINYLAPSVAYFLTILAGTGHTVFSLIPVIVEVSQSQNIKPKVPLSLAVVSSQVGITASPVSAAVVFMSGILE
PLGANYLTLLMIWIPTTFLACMFTAFIMGFTNLKLDSDPNYLERLKMGKISPPKIKEEKEVSKNAKLSLWIFIGGVVAIV
FYASAISKNIALISPVILGRDQAIVSFMLSVAALIAIFCKINANEIAHSSVFKSGMQACVCVLGVAWLGDTFVSNHLNEI
ERYASFLIADYPFLLAVALFFASMLLYSQAATSKALIPSVIIALGIGANHTEHLYIIVASFASVSALFVLPTYPTLLGAI
AMDNTGTTKMGRYVFDHAFLIPGVLVVALSVALGFVVAPLVL

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=440, Percent_Identity=52.5, Blast_Score=407, Evalue=1e-114,
Organism=Escherichia coli, GI1790565, Length=418, Percent_Identity=36.1244019138756, Blast_Score=236, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 47290; Mature: 47290

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]