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The map label for this gene is slyD [H]

Identifier: 109947177

GI number: 109947177

Start: 520582

End: 521136

Strand: Direct

Name: slyD [H]

Synonym: Hac_0590

Alternate gene names: 109947177

Gene position: 520582-521136 (Clockwise)

Preceding gene: 109947176

Following gene: 109947178

Centisome position: 33.5

GC content: 43.06

Gene sequence:

>555_bases
ATGCAAAACCATGATTTAGAACCAATCAAACAAGCCGCTTTGATTGAATATGAAGTGAGAGAACATGGCTCTAGCGAAGT
GCTAGACAGCAATATCGCTAAAGAGCCTTTAGAATTTATCATAGGTGCCCATCAAATTATAGCAGGGTTAGAAAAAGCGG
TATTGAAGGCTCAAATTGGCGAGTGGGAAGAGGTTGTTATTACCCCAGAGGAAGCTTATGGGGTTTATGAAAGCGGTTAT
TTGCAAGAAGTCCCTAGGGAGCAATTTGAAGGCATTGAATTGGAAAAAGGCATGAGCGTTTTTGGGCAAACTGAAGAGAA
TCAAACCATTCAAGCCACTATTAAAGACTTTAGCGGCACGCATGTGATGGTGGATTATAACCATCCTTTAGCCGGAAAAA
CTTTAGCGTTTCGTTTCAAGGTTTTAGGGTTTAGGGAAGTGAGCGAAGAAGAAATTTTAGCTTCACACCATGGTGGTGGG
GGAGGCTGTTGTGGCGGTCATGGTGCTCATAAGCATAAAGATGGGGGTTGTGGTTGCTCATGTTCGCATGGGTAA

Upstream 100 bases:

>100_bases
AATTACCATAAATTCTTAAACACTTTGCAGCGCTTGTATCCTTCAAGCGATCAAGCTAAAAAAGCCAAAAAAATTTTAGA
AAATAAGGAGAAAAGCATTC

Downstream 100 bases:

>100_bases
ATGGGGGAATGTTTAAAAAGGCAAGGTCATGAATAGTTCTAACCTCAAAAATTGGTTGTTCCCCACTATTTGCTTTTTTT
TATTTTGTTATATTTTAATT

Product: peptidyl-prolyl cis-trans isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MQNHDLEPIKQAALIEYEVREHGSSEVLDSNIAKEPLEFIIGAHQIIAGLEKAVLKAQIGEWEEVVITPEEAYGVYESGY
LQEVPREQFEGIELEKGMSVFGQTEENQTIQATIKDFSGTHVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGG
GGCCGGHGAHKHKDGGCGCSCSHG

Sequences:

>Translated_184_residues
MQNHDLEPIKQAALIEYEVREHGSSEVLDSNIAKEPLEFIIGAHQIIAGLEKAVLKAQIGEWEEVVITPEEAYGVYESGY
LQEVPREQFEGIELEKGMSVFGQTEENQTIQATIKDFSGTHVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGG
GGCCGGHGAHKHKDGGCGCSCSHG
>Mature_184_residues
MQNHDLEPIKQAALIEYEVREHGSSEVLDSNIAKEPLEFIIGAHQIIAGLEKAVLKAQIGEWEEVVITPEEAYGVYESGY
LQEVPREQFEGIELEKGMSVFGQTEENQTIQATIKDFSGTHVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGG
GGCCGGHGAHKHKDGGCGCSCSHG

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=139, Percent_Identity=33.0935251798561, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 20063; Mature: 20063

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNHDLEPIKQAALIEYEVREHGSSEVLDSNIAKEPLEFIIGAHQIIAGLEKAVLKAQIG
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EWEEVVITPEEAYGVYESGYLQEVPREQFEGIELEKGMSVFGQTEENQTIQATIKDFSGT
CCEEEEECCHHHCCCCCCCHHHHCCHHHHCCCCHHCCCHHHCCCCCCCEEEEEEECCCCC
HVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGGGGCCGGHGAHKHKDGGCGCS
EEEEECCCCCCCCCEEEEEEECCCHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
CSHG
CCCC
>Mature Secondary Structure
MQNHDLEPIKQAALIEYEVREHGSSEVLDSNIAKEPLEFIIGAHQIIAGLEKAVLKAQIG
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EWEEVVITPEEAYGVYESGYLQEVPREQFEGIELEKGMSVFGQTEENQTIQATIKDFSGT
CCEEEEECCHHHCCCCCCCHHHHCCHHHHCCCCHHCCCHHHCCCCCCCEEEEEEECCCCC
HVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGGGGCCGGHGAHKHKDGGCGCS
EEEEECCCCCCCCCEEEEEEECCCHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
CSHG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]