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The map label for this gene is yoaE [H]

Identifier: 108812525

GI number: 108812525

Start: 2646084

End: 2647460

Strand: Reverse

Name: yoaE [H]

Synonym: YPN_2364

Alternate gene names: 108812525

Gene position: 2647460-2646084 (Counterclockwise)

Preceding gene: 108812531

Following gene: 108812523

Centisome position: 58.38

GC content: 52.07

Gene sequence:

>1377_bases
ATGCGTTTGGGGCTGTTGTCGGTCATTTCATGGATGGTCACGCTTACGACACCGCTGTTCAGCGTCGGTGCGTTTAATTT
CGCTGGGCGAGATTTGATTTTGCTGGTGGGGGGGTTGTTCCTGCTGTTTAAAGCCACCACCGAGCTACATGAACGGTTAG
AAGGTAATCAGCACAATGATGGGGCGAACCGGGGCTATGCCAGCTTCTGGGCGGTCGTGGTCCAAATTGTCATCCTGGAT
GCGGTCTTCTCCCTGGATGCAGTGATTACGGCGGTAGGGATGGTCAACGACTTGCCTATCATGATGACAGCCGTGGTGAT
TGCCATGGGGGTCATGTTACTGGCCTCGAAATCCCTGACCCGATTTGTGAACGAGCACCCAACGGTGGTCGTGCTATGTC
TGAGCTTCCTGTTGATGATCGGCTTGAGTTTGATTGCCGAAGGTTTTGGCTTCCACATTCCGAAAGGTTACCTGTATGCC
GCGATTGGCTTCTCAATCTTGATTGAGTTGTTTAACCAGATTGCGCGTCGTAACTTCATCAAACATGAATCGCGTTTACC
AAGACGTCAACGTACAGCAGAAGCGATCATCCGTCTGATGGGTGGGCGTCAGCAGCAGGAACAACAGAGTGGTGACCCTC
AACAGGCAGTACCAACAGAAGCCTTTGCTGAAGAAGAACGCTATATGATCAGCGGGGTATTAACGCTGGCCTCGCGATCA
TTACGCAGCGTAATGACGCCGCGTACCGAAATTTCTTGGGTTGATTGCAACCGTTCACAAGCCGAAATTCGCGAGCAGTT
GTTAGATACCCCACACAGTTTGTTCCCTGTTTGCCGCGACTCTTTGGATCAAATCATTGGTGTGGTTCGCGCTAAAGACC
TGCTGGTGGCGATTGAGCGGGGTGAGTCTATTTGTGATTTTGCCGCGACAACCCCGCCAATCGTGGTGCCTGATACCATG
GATGTGATTAATCTGTTGGGGGTATTGCGCAAAGCCAAGGGCCGCCTGGTGGTGGTGAATGACGAGTTCGGCGTGGTGCA
GGGTCTGGTAACACCGCTGGATGTCCTGGAAGCGATTGCCGGTGAATTCCCTGATGAAGATGAAACGCCAGATATTATTG
CCGATGGTGATGGTTGGTTGGTGAAAGGGGGGGCAGATCTGCACTCGTTGGAACAGGCGCTGGATTGCCAGACACTGGTT
AGCCCAACCGCTGATTATGCCTCGTTAGCCGGTTTACTGTTGTCTCATTCGGGCCATATGCCAACGGCAGGGGATGTGAT
TGAGCTGCATAACCTGCGCTTCCAGATTATGGACGTCTCAGATTACCGTATTGAGCTGGTGCGCATTACCAAGCTGAGTA
ATGAGTTGGAAGAGTAA

Upstream 100 bases:

>100_bases
TTCTTATTTTCGGAGTCTGACATGGAACTTTTAATGGACCCCTCAATTTGGGCAGGGTTGCTTACACTGGTGGTATTAGA
GATTGTTCTGGGCATTGATC

Downstream 100 bases:

>100_bases
GCAGAGAGTGGAACCTCAGGGGCGCTTCGGCTCCCCTGAGGTTATTGACAACGTACCCGCGACGGAGGTAACAGACAGAA
CGCAAAGACGCCGTAAACCC

Product: membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MRLGLLSVISWMVTLTTPLFSVGAFNFAGRDLILLVGGLFLLFKATTELHERLEGNQHNDGANRGYASFWAVVVQIVILD
AVFSLDAVITAVGMVNDLPIMMTAVVIAMGVMLLASKSLTRFVNEHPTVVVLCLSFLLMIGLSLIAEGFGFHIPKGYLYA
AIGFSILIELFNQIARRNFIKHESRLPRRQRTAEAIIRLMGGRQQQEQQSGDPQQAVPTEAFAEEERYMISGVLTLASRS
LRSVMTPRTEISWVDCNRSQAEIREQLLDTPHSLFPVCRDSLDQIIGVVRAKDLLVAIERGESICDFAATTPPIVVPDTM
DVINLLGVLRKAKGRLVVVNDEFGVVQGLVTPLDVLEAIAGEFPDEDETPDIIADGDGWLVKGGADLHSLEQALDCQTLV
SPTADYASLAGLLLSHSGHMPTAGDVIELHNLRFQIMDVSDYRIELVRITKLSNELEE

Sequences:

>Translated_458_residues
MRLGLLSVISWMVTLTTPLFSVGAFNFAGRDLILLVGGLFLLFKATTELHERLEGNQHNDGANRGYASFWAVVVQIVILD
AVFSLDAVITAVGMVNDLPIMMTAVVIAMGVMLLASKSLTRFVNEHPTVVVLCLSFLLMIGLSLIAEGFGFHIPKGYLYA
AIGFSILIELFNQIARRNFIKHESRLPRRQRTAEAIIRLMGGRQQQEQQSGDPQQAVPTEAFAEEERYMISGVLTLASRS
LRSVMTPRTEISWVDCNRSQAEIREQLLDTPHSLFPVCRDSLDQIIGVVRAKDLLVAIERGESICDFAATTPPIVVPDTM
DVINLLGVLRKAKGRLVVVNDEFGVVQGLVTPLDVLEAIAGEFPDEDETPDIIADGDGWLVKGGADLHSLEQALDCQTLV
SPTADYASLAGLLLSHSGHMPTAGDVIELHNLRFQIMDVSDYRIELVRITKLSNELEE
>Mature_458_residues
MRLGLLSVISWMVTLTTPLFSVGAFNFAGRDLILLVGGLFLLFKATTELHERLEGNQHNDGANRGYASFWAVVVQIVILD
AVFSLDAVITAVGMVNDLPIMMTAVVIAMGVMLLASKSLTRFVNEHPTVVVLCLSFLLMIGLSLIAEGFGFHIPKGYLYA
AIGFSILIELFNQIARRNFIKHESRLPRRQRTAEAIIRLMGGRQQQEQQSGDPQQAVPTEAFAEEERYMISGVLTLASRS
LRSVMTPRTEISWVDCNRSQAEIREQLLDTPHSLFPVCRDSLDQIIGVVRAKDLLVAIERGESICDFAATTPPIVVPDTM
DVINLLGVLRKAKGRLVVVNDEFGVVQGLVTPLDVLEAIAGEFPDEDETPDIIADGDGWLVKGGADLHSLEQALDCQTLV
SPTADYASLAGLLLSHSGHMPTAGDVIELHNLRFQIMDVSDYRIELVRITKLSNELEE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Escherichia coli, GI1788119, Length=454, Percent_Identity=71.3656387665198, Blast_Score=645, Evalue=0.0,
Organism=Escherichia coli, GI87082033, Length=462, Percent_Identity=45.2380952380952, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1789197, Length=178, Percent_Identity=50.561797752809, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1790664, Length=235, Percent_Identity=26.3829787234043, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1786879, Length=226, Percent_Identity=29.2035398230088, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI145693175, Length=231, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 50334; Mature: 50334

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHCCCEEEEEECCCCEEEEHHHHHHHHHHCC
>Mature Secondary Structure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CCCCCHHHHCCCEEEEEECCCCEEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]