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The map label for this gene is ptrB [H]

Identifier: 108812504

GI number: 108812504

Start: 2624396

End: 2626447

Strand: Reverse

Name: ptrB [H]

Synonym: YPN_2343

Alternate gene names: 108812504

Gene position: 2626447-2624396 (Counterclockwise)

Preceding gene: 108812505

Following gene: 108812503

Centisome position: 57.92

GC content: 46.54

Gene sequence:

>2052_bases
ATGATGACTCCCCCAAAAGCAGATAAACGCCCTTATCCGATGACGCGACACGGTGATACGCGTGTGGATGACTATTACTG
GCTACGTGATGATGAACGTACAGATGCTGATGTACTGAATTATTTGCAAGCTGAAAATGCTTTCACGGCGGCGGTGCTTA
AGCCACAACAACAGTTGCGTGAAACCTTGTATCAGGAAATGGTTGGCCGTATTCCTCCACAAGAGGAGTCAGTGCCGTAT
GTTCGCAACGGCTACCGTTATCAAACCCGTTTTGAGCCGGGTAACGAGTACGCTATCTATGTTCGGCAACCCGTCAGTAC
AGACAGCGACTGGGAAACGCTATTGGATGGTAATCAGCGTGCCGAGGGCCATGAGTTTTATACCTTAGGCGGTTTAGATG
TCAGTCCTGATAACCAGTTACTGGCGGTGGCAGAAGATTATCTATCACGTCGCCAATATGACATCAGGATAAAAAACCTA
TCCAGTGGGGGCTGGCACGATGAAGTTATCAGTAATACGTCAGGCGGATTTGAGTGGGCAAATGATTCAAAAACGCTGTA
TTACGTACGAAAACATGAAAAAACGTTATTGCCTTATCAAGTGTATCGGCATGTGGTGGGTACTGATCCTGAGCAAGATA
AATTAATTTATCAGGAATCAGACGACACTTTTTATGTCAGCTTGGAAAAAACCACGTCTGAACGTTTTATTCTGATTCAC
CTTAGCAGCACGACGACGTCTGAGATTTTGTTGCTGGATGCTGATCTGCCTGAGCCGGTACCGCAGGTTTTTGCGCCACG
CCGTAAAGACCATGAATATGGTGTAGACCACTATAAACAGCACTTCTATATTCGCTCCAATAAAGAGGGGAAGAATTTCG
GGCTCTATAAAATTGAAGACAGCCAAGGGTGCAGTGACTTTGCCGATGAGTCTCAATGGGCGTTACTGATTGCACCAAGA
ACGGACGTTATGCTGGAAGGATTCAGTTTATTCCGCGATTGGCTGGTGGTCGAAGAACGCAGTGAAGGGTTGACGCACCT
ACGGCAAATCCATTGGTCTACTGGAGAAGAAAAATCCATCACTTTTGATGATCCAACCTACGTAACGTGGCTTGCTTACA
ATCCAGAACCAGAAACGGCACTGTTGCGCTATGGTTACTCCTCAATGACCACGCCAAGCTCCATGTTTGAGATTAATATG
GACAGTGGTGAGCGCCAGTTACTAAAGCAACAGGAAGTAAAGGATTTCACCCCTGAAAAGTATCGCAGTGAACGTATTTG
GGTTACCGCATCTGATGGTGTGAAAATACCGGTTTCGTTGGTTTATCATCGCGACTACTTTGTTTCTGGTAGCAATCCAT
TATTGGTGTATGCCTATGGTTCGTACGGTAGCAGTATGGATCCCGTCTTCAGCAGTAGCCGTTTGAGCTTATTGGATCGC
GGTTTTGTGTTTGCTCTGGCACACATTCGTGGGGGCGGAGAACTGGGGCAGCAATGGTATGAAGATGGCAAATTACTCAA
CAAATTAAATACCTTCAGCGACTTTACTGATGTAACGAAAGCCTTAGTGAACGAAGGATATGGGGATGCTCAGCGCGTTT
TTGCGATGGGAGGCAGTGCCGGAGGCTTGCTGATGGGCGTCATCGTCAATCAGGCCCCTGAATTATATAAGGCGGTTGTG
GCACAGGTTCCCTTTGTTGATGTGGTCACGACCATGCTGGATGAGTCGATTCCACTCACGACAGGTGAATACGATGAGTG
GGGCAACCCTAACGATAAGGTCTATTACGATTATATTAAGCAATATAGCCCTTACGATCAGGTTAAAGCGCAGGATTACC
CGCACATGCTGGTAACGACTGGGCTGCATGATTCTCAAGTCCAGTATTGGGAACCCGCTAAATGGGTCGCTAAACTGCGT
GAAATGAAGACTGATGACCACCAATTACTGCTTTACACCGATATGGACTCGGGCCATGGCGGTAAATCAGGTCGCTTCAA
AGCTTATGAAGATATTGCTTTGGAGTATGCATTTATTCTGTCGTTGATTTAA

Upstream 100 bases:

>100_bases
TTAAATGCCCTTGTTTATCAGCAAACTATATGTTTTTCTTTGCATCAACAGGTAATCGTACCACTCTCGTGATAACGCAC
ATAGATGGATAACCTAATCA

Downstream 100 bases:

>100_bases
TGCAATGATGTCTTTATACCCAAAATAATGCGGCGCGTTGCAGGAAGGCGGTAACTGAGTAGGTCCCCAGGAGCTTAATT
TATTTTAAGATCAACGACCC

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MMTPPKADKRPYPMTRHGDTRVDDYYWLRDDERTDADVLNYLQAENAFTAAVLKPQQQLRETLYQEMVGRIPPQEESVPY
VRNGYRYQTRFEPGNEYAIYVRQPVSTDSDWETLLDGNQRAEGHEFYTLGGLDVSPDNQLLAVAEDYLSRRQYDIRIKNL
SSGGWHDEVISNTSGGFEWANDSKTLYYVRKHEKTLLPYQVYRHVVGTDPEQDKLIYQESDDTFYVSLEKTTSERFILIH
LSSTTTSEILLLDADLPEPVPQVFAPRRKDHEYGVDHYKQHFYIRSNKEGKNFGLYKIEDSQGCSDFADESQWALLIAPR
TDVMLEGFSLFRDWLVVEERSEGLTHLRQIHWSTGEEKSITFDDPTYVTWLAYNPEPETALLRYGYSSMTTPSSMFEINM
DSGERQLLKQQEVKDFTPEKYRSERIWVTASDGVKIPVSLVYHRDYFVSGSNPLLVYAYGSYGSSMDPVFSSSRLSLLDR
GFVFALAHIRGGGELGQQWYEDGKLLNKLNTFSDFTDVTKALVNEGYGDAQRVFAMGGSAGGLLMGVIVNQAPELYKAVV
AQVPFVDVVTTMLDESIPLTTGEYDEWGNPNDKVYYDYIKQYSPYDQVKAQDYPHMLVTTGLHDSQVQYWEPAKWVAKLR
EMKTDDHQLLLYTDMDSGHGGKSGRFKAYEDIALEYAFILSLI

Sequences:

>Translated_683_residues
MMTPPKADKRPYPMTRHGDTRVDDYYWLRDDERTDADVLNYLQAENAFTAAVLKPQQQLRETLYQEMVGRIPPQEESVPY
VRNGYRYQTRFEPGNEYAIYVRQPVSTDSDWETLLDGNQRAEGHEFYTLGGLDVSPDNQLLAVAEDYLSRRQYDIRIKNL
SSGGWHDEVISNTSGGFEWANDSKTLYYVRKHEKTLLPYQVYRHVVGTDPEQDKLIYQESDDTFYVSLEKTTSERFILIH
LSSTTTSEILLLDADLPEPVPQVFAPRRKDHEYGVDHYKQHFYIRSNKEGKNFGLYKIEDSQGCSDFADESQWALLIAPR
TDVMLEGFSLFRDWLVVEERSEGLTHLRQIHWSTGEEKSITFDDPTYVTWLAYNPEPETALLRYGYSSMTTPSSMFEINM
DSGERQLLKQQEVKDFTPEKYRSERIWVTASDGVKIPVSLVYHRDYFVSGSNPLLVYAYGSYGSSMDPVFSSSRLSLLDR
GFVFALAHIRGGGELGQQWYEDGKLLNKLNTFSDFTDVTKALVNEGYGDAQRVFAMGGSAGGLLMGVIVNQAPELYKAVV
AQVPFVDVVTTMLDESIPLTTGEYDEWGNPNDKVYYDYIKQYSPYDQVKAQDYPHMLVTTGLHDSQVQYWEPAKWVAKLR
EMKTDDHQLLLYTDMDSGHGGKSGRFKAYEDIALEYAFILSLI
>Mature_683_residues
MMTPPKADKRPYPMTRHGDTRVDDYYWLRDDERTDADVLNYLQAENAFTAAVLKPQQQLRETLYQEMVGRIPPQEESVPY
VRNGYRYQTRFEPGNEYAIYVRQPVSTDSDWETLLDGNQRAEGHEFYTLGGLDVSPDNQLLAVAEDYLSRRQYDIRIKNL
SSGGWHDEVISNTSGGFEWANDSKTLYYVRKHEKTLLPYQVYRHVVGTDPEQDKLIYQESDDTFYVSLEKTTSERFILIH
LSSTTTSEILLLDADLPEPVPQVFAPRRKDHEYGVDHYKQHFYIRSNKEGKNFGLYKIEDSQGCSDFADESQWALLIAPR
TDVMLEGFSLFRDWLVVEERSEGLTHLRQIHWSTGEEKSITFDDPTYVTWLAYNPEPETALLRYGYSSMTTPSSMFEINM
DSGERQLLKQQEVKDFTPEKYRSERIWVTASDGVKIPVSLVYHRDYFVSGSNPLLVYAYGSYGSSMDPVFSSSRLSLLDR
GFVFALAHIRGGGELGQQWYEDGKLLNKLNTFSDFTDVTKALVNEGYGDAQRVFAMGGSAGGLLMGVIVNQAPELYKAVV
AQVPFVDVVTTMLDESIPLTTGEYDEWGNPNDKVYYDYIKQYSPYDQVKAQDYPHMLVTTGLHDSQVQYWEPAKWVAKLR
EMKTDDHQLLLYTDMDSGHGGKSGRFKAYEDIALEYAFILSLI

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172438, Length=518, Percent_Identity=28.5714285714286, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI284172431, Length=518, Percent_Identity=28.5714285714286, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI284172420, Length=518, Percent_Identity=28.5714285714286, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI284172413, Length=518, Percent_Identity=28.5714285714286, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI70778815, Length=518, Percent_Identity=28.5714285714286, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI41349456, Length=708, Percent_Identity=25.1412429378531, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI108860686, Length=240, Percent_Identity=36.6666666666667, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI108860692, Length=214, Percent_Identity=38.785046728972, Blast_Score=156, Evalue=5e-38,
Organism=Escherichia coli, GI1788150, Length=680, Percent_Identity=63.8235294117647, Blast_Score=928, Evalue=0.0,
Organism=Drosophila melanogaster, GI24583414, Length=727, Percent_Identity=24.7592847317744, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI221510989, Length=693, Percent_Identity=23.953823953824, Blast_Score=159, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78500; Mature: 78500

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTPPKADKRPYPMTRHGDTRVDDYYWLRDDERTDADVLNYLQAENAFTAAVLKPQQQLR
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEHCCCHHHHH
ETLYQEMVGRIPPQEESVPYVRNGYRYQTRFEPGNEYAIYVRQPVSTDSDWETLLDGNQR
HHHHHHHHHCCCCCCCCCCHHHCCEEEEEEECCCCCEEEEEECCCCCCCCHHHHHCCCCC
AEGHEFYTLGGLDVSPDNQLLAVAEDYLSRRQYDIRIKNLSSGGWHDEVISNTSGGFEWA
CCCCEEEEECCEEECCCCCEEHHHHHHHCCCEEEEEEEECCCCCCCHHHHCCCCCCCEEC
NDSKTLYYVRKHEKTLLPYQVYRHVVGTDPEQDKLIYQESDDTFYVSLEKTTSERFILIH
CCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCEEEEECCCEEEEEEEECCCCEEEEEE
LSSTTTSEILLLDADLPEPVPQVFAPRRKDHEYGVDHYKQHFYIRSNKEGKNFGLYKIED
ECCCCCCEEEEEECCCCCCCHHHHCCCCCCCCCCCCHHHEEEEEEECCCCCCCCEEEEEC
SQGCSDFADESQWALLIAPRTDVMLEGFSLFRDWLVVEERSEGLTHLRQIHWSTGEEKSI
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHEECHHHHHHHHHHHHCCCCCCCEE
TFDDPTYVTWLAYNPEPETALLRYGYSSMTTPSSMFEINMDSGERQLLKQQEVKDFTPEK
EECCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCHH
YRSERIWVTASDGVKIPVSLVYHRDYFVSGSNPLLVYAYGSYGSSMDPVFSSSRLSLLDR
HCCCEEEEEECCCCEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHHHC
GFVFALAHIRGGGELGQQWYEDGKLLNKLNTFSDFTDVTKALVNEGYGDAQRVFAMGGSA
CCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEECCCC
GGLLMGVIVNQAPELYKAVVAQVPFVDVVTTMLDESIPLTTGEYDEWGNPNDKVYYDYIK
CCHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHH
QYSPYDQVKAQDYPHMLVTTGLHDSQVQYWEPAKWVAKLREMKTDDHQLLLYTDMDSGHG
CCCCHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCC
GKSGRFKAYEDIALEYAFILSLI
CCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMTPPKADKRPYPMTRHGDTRVDDYYWLRDDERTDADVLNYLQAENAFTAAVLKPQQQLR
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEHCCCHHHHH
ETLYQEMVGRIPPQEESVPYVRNGYRYQTRFEPGNEYAIYVRQPVSTDSDWETLLDGNQR
HHHHHHHHHCCCCCCCCCCHHHCCEEEEEEECCCCCEEEEEECCCCCCCCHHHHHCCCCC
AEGHEFYTLGGLDVSPDNQLLAVAEDYLSRRQYDIRIKNLSSGGWHDEVISNTSGGFEWA
CCCCEEEEECCEEECCCCCEEHHHHHHHCCCEEEEEEEECCCCCCCHHHHCCCCCCCEEC
NDSKTLYYVRKHEKTLLPYQVYRHVVGTDPEQDKLIYQESDDTFYVSLEKTTSERFILIH
CCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCEEEEECCCEEEEEEEECCCCEEEEEE
LSSTTTSEILLLDADLPEPVPQVFAPRRKDHEYGVDHYKQHFYIRSNKEGKNFGLYKIED
ECCCCCCEEEEEECCCCCCCHHHHCCCCCCCCCCCCHHHEEEEEEECCCCCCCCEEEEEC
SQGCSDFADESQWALLIAPRTDVMLEGFSLFRDWLVVEERSEGLTHLRQIHWSTGEEKSI
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHEECHHHHHHHHHHHHCCCCCCCEE
TFDDPTYVTWLAYNPEPETALLRYGYSSMTTPSSMFEINMDSGERQLLKQQEVKDFTPEK
EECCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCHH
YRSERIWVTASDGVKIPVSLVYHRDYFVSGSNPLLVYAYGSYGSSMDPVFSSSRLSLLDR
HCCCEEEEEECCCCEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCCCHHHHHHC
GFVFALAHIRGGGELGQQWYEDGKLLNKLNTFSDFTDVTKALVNEGYGDAQRVFAMGGSA
CCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEECCCC
GGLLMGVIVNQAPELYKAVVAQVPFVDVVTTMLDESIPLTTGEYDEWGNPNDKVYYDYIK
CCHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEHHHHH
QYSPYDQVKAQDYPHMLVTTGLHDSQVQYWEPAKWVAKLREMKTDDHQLLLYTDMDSGHG
CCCCHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCC
GKSGRFKAYEDIALEYAFILSLI
CCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]