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The map label for this gene is yvoA [H]

Identifier: 108812396

GI number: 108812396

Start: 2523173

End: 2523970

Strand: Reverse

Name: yvoA [H]

Synonym: YPN_2235

Alternate gene names: 108812396

Gene position: 2523970-2523173 (Counterclockwise)

Preceding gene: 108812398

Following gene: 108812394

Centisome position: 55.66

GC content: 54.64

Gene sequence:

>798_bases
ATGCCGGGTGGAATGGGTGGAAAGGGTGTGGACAGAAAATTCATCGAGACACTGAAAACATACTGTGATGATGCTAACCG
GGGAGGGGGTCCGCTCTACCAGCGTCTGGAGAAAGGTTTCCGCGATCTGATCACCCGTGGTGAGCTAAAAGCCGGATACG
CGATTCCCAGCGAACGCGAACTTTCGGAACGCTTGAATCTGTCCAGAGTGACAGTCCGGCGTGCGTTAAGTGAACTGGCT
AACGCGCAGGTTATCGTGCAGCGTCGTGGAGCGAGAAGTACTGTGGCGGGAAGGGTTGAAAAGCCGCTGTCTTCGCTGAC
CAGCTTTAGTGAGGATATGATTTCACGTGGCTATGAGCCAGGCGCACGCTGGCTACAGAAAGAGCTTACTCACGCTTCTC
CCTCGGAAATTATTGCACTGAATCTGTCTCCAGGTGCTCTGGTGTGGCGTCTCAAGCGCCTGCGTACCGTAGATGAACAC
CCGATGGCAGTGGAGATCGCCGTGGTGCCGCAGATGTTTATTCCAGAGATGGATGAACTGAGGGATTCGCTTTATTCAGT
ACTGCAGTTGCACGGGTTTATGCCCGCCCGCGCGTTACAGCGTATTCGAGCAGAACCGCTGAGTCGCGATCACAGCCAAC
TGTTAGATATGCCTGCTCACAGCCCGGCGCTGCATGTTGAGCGCCATTGCTATCTGGAAGATGGCCGCCCGATTGAATAC
ACCCATACCTGGTATCGGGGCGACAGTTACGATTTTCTGGTTGAACTTCAGCGCGACATCACCCCCGGTCTGTCATGA

Upstream 100 bases:

>100_bases
CGGCTCAAACCAATTGCTGACCATACCAGATAATACCAGTTGCACGGAAAGGGTATCATCAACGCTATGCCAGATAGATA
ACATCAGGTAATCTCCCTAC

Downstream 100 bases:

>100_bases
ACCCGTCTTACTGATGCTGAGCTCCTTTGGCAACACTCAGTCATCCTGTATGTACCACCACCCAACATCGGGGTAACTGG
CAGGTTGAATCGCGCAGGAA

Product: GntR family putative transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MPGGMGGKGVDRKFIETLKTYCDDANRGGGPLYQRLEKGFRDLITRGELKAGYAIPSERELSERLNLSRVTVRRALSELA
NAQVIVQRRGARSTVAGRVEKPLSSLTSFSEDMISRGYEPGARWLQKELTHASPSEIIALNLSPGALVWRLKRLRTVDEH
PMAVEIAVVPQMFIPEMDELRDSLYSVLQLHGFMPARALQRIRAEPLSRDHSQLLDMPAHSPALHVERHCYLEDGRPIEY
THTWYRGDSYDFLVELQRDITPGLS

Sequences:

>Translated_265_residues
MPGGMGGKGVDRKFIETLKTYCDDANRGGGPLYQRLEKGFRDLITRGELKAGYAIPSERELSERLNLSRVTVRRALSELA
NAQVIVQRRGARSTVAGRVEKPLSSLTSFSEDMISRGYEPGARWLQKELTHASPSEIIALNLSPGALVWRLKRLRTVDEH
PMAVEIAVVPQMFIPEMDELRDSLYSVLQLHGFMPARALQRIRAEPLSRDHSQLLDMPAHSPALHVERHCYLEDGRPIEY
THTWYRGDSYDFLVELQRDITPGLS
>Mature_264_residues
PGGMGGKGVDRKFIETLKTYCDDANRGGGPLYQRLEKGFRDLITRGELKAGYAIPSERELSERLNLSRVTVRRALSELAN
AQVIVQRRGARSTVAGRVEKPLSSLTSFSEDMISRGYEPGARWLQKELTHASPSEIIALNLSPGALVWRLKRLRTVDEHP
MAVEIAVVPQMFIPEMDELRDSLYSVLQLHGFMPARALQRIRAEPLSRDHSQLLDMPAHSPALHVERHCYLEDGRPIEYT
HTWYRGDSYDFLVELQRDITPGLS

Specific function: Acts as a weak repressor of yflG expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788418, Length=225, Percent_Identity=28.4444444444444, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786950, Length=235, Percent_Identity=31.4893617021277, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI87082252, Length=234, Percent_Identity=23.0769230769231, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790540, Length=220, Percent_Identity=28.1818181818182, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 29978; Mature: 29847

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGGMGGKGVDRKFIETLKTYCDDANRGGGPLYQRLEKGFRDLITRGELKAGYAIPSERE
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
LSERLNLSRVTVRRALSELANAQVIVQRRGARSTVAGRVEKPLSSLTSFSEDMISRGYEP
HHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
GARWLQKELTHASPSEIIALNLSPGALVWRLKRLRTVDEHPMAVEIAVVPQMFIPEMDEL
HHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHCCCHHHH
RDSLYSVLQLHGFMPARALQRIRAEPLSRDHSQLLDMPAHSPALHVERHCYLEDGRPIEY
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEHHHEEEECCCCCEEE
THTWYRGDSYDFLVELQRDITPGLS
EEEEECCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PGGMGGKGVDRKFIETLKTYCDDANRGGGPLYQRLEKGFRDLITRGELKAGYAIPSERE
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
LSERLNLSRVTVRRALSELANAQVIVQRRGARSTVAGRVEKPLSSLTSFSEDMISRGYEP
HHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
GARWLQKELTHASPSEIIALNLSPGALVWRLKRLRTVDEHPMAVEIAVVPQMFIPEMDEL
HHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHCCCHHHH
RDSLYSVLQLHGFMPARALQRIRAEPLSRDHSQLLDMPAHSPALHVERHCYLEDGRPIEY
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCCCEEHHHEEEECCCCCEEE
THTWYRGDSYDFLVELQRDITPGLS
EEEEECCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]