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The map label for this gene is tqsA [H]

Identifier: 108812209

GI number: 108812209

Start: 2311959

End: 2313017

Strand: Reverse

Name: tqsA [H]

Synonym: YPN_2047

Alternate gene names: 108812209

Gene position: 2313017-2311959 (Counterclockwise)

Preceding gene: 108812210

Following gene: 108812206

Centisome position: 51.01

GC content: 46.08

Gene sequence:

>1059_bases
ATGACAACACCTGTGGTGAGTAACCAAGGGCTACGATTAGTGGCGATGCTGGCAATGCTGGTGGTCATCATGGCCGGTAT
TAAAGCGGCATCACCAATTGTCGTCCCCTTCCTGTTGGCTATTTTTCTCGCGATCGTGCTGAATCCCTTAGTCAAATTGC
TTGAGAGGATAAAAATCCCACGGACACTGGCGGTTATTTTACTCGTAACCATTATTATTTTACTGATGGTGCTGCTGTTT
GGCCGCTTAGGCTCTTCACTCAATGAGTTCGCACGCTCATTACCGCAATATCGCGGCATGATGCTGGAGAAAATGCGCGA
TCTGCAAGAATTTGCCCTGCATTTTAATATTGAATTCTCAGTAGATGACATCATGAAGTATGTCGATCCGAGCATGGCGA
TGAACTTTGTCACCCGTCTACTCAGCCACCTGTCTGGTGCCATGACCAGCACGTTCTTATTACTGATGACCGTGGTCTTC
ATGTTGTTTGAAGTAGAACGGATGCCGTATAAAGTGCAATTGATGTTTGATAATCCCGAAAAAGGGAATGCTATCCTCAA
ACGAGCACTAAATGGTGTCACCCATTATCTGGTGATCAAAACGATTATTAGCATTGCCACGGGGATTGTCATTTGGCTGT
TCTTGGCAGCTATGGGCGTTAGATTCGCCTTCCTTTGGGGGTTATTGGCGTTTGTACTGAATTATATTCCCAACATTGGG
TCGGTGCTGGCTGCTATCCCACCCATCATTCAGGCACTGTTATTTAACGGTTTTGCTGATGCTTTTGCGGTAACCGGCGG
TTATATTTTGATTAACTTGATAGGGGGCAATATTATCGACCCGCGTATGATGGGCCGTGGGCTGGGTTTATCGACGTTGG
TCGTCTTCTTATCATTAATTTTCTGGGGCTGGCTATTGGGCCCAGTCGGTATGTTGCTCTCGGTGCCTTTAACTATTATT
GCTAAAATTGTCCTTGAGCTAACCCCTGCGGGTTATAGATTTGCCGTTTTATTGAGTGATGGTAAACCCGCTAAGGTTGA
AGAAGAGCAAGCGCTCTGA

Upstream 100 bases:

>100_bases
GACTTAAAATTAGGCTTTAGTTGACGTTGTCGGTTACTTTATCCGCTGGCGTCTCTTTTTTCCGTCTTGAGCAGTGGCGG
TTCGAATACAAGGATTGATA

Downstream 100 bases:

>100_bases
TATCACGGTGGTTAGAAAACCCTCAGGGCCACTGGTTAATTGGCCTACGGCCCTGAGGAACCGAAAATGGGGTAAGGGAG
CCGTGATTAAGAAGAATGAT

Product: putative transport protein

Products: NA

Alternate protein names: Transport of quorum-sensing signal protein [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MTTPVVSNQGLRLVAMLAMLVVIMAGIKAASPIVVPFLLAIFLAIVLNPLVKLLERIKIPRTLAVILLVTIIILLMVLLF
GRLGSSLNEFARSLPQYRGMMLEKMRDLQEFALHFNIEFSVDDIMKYVDPSMAMNFVTRLLSHLSGAMTSTFLLLMTVVF
MLFEVERMPYKVQLMFDNPEKGNAILKRALNGVTHYLVIKTIISIATGIVIWLFLAAMGVRFAFLWGLLAFVLNYIPNIG
SVLAAIPPIIQALLFNGFADAFAVTGGYILINLIGGNIIDPRMMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTII
AKIVLELTPAGYRFAVLLSDGKPAKVEEEQAL

Sequences:

>Translated_352_residues
MTTPVVSNQGLRLVAMLAMLVVIMAGIKAASPIVVPFLLAIFLAIVLNPLVKLLERIKIPRTLAVILLVTIIILLMVLLF
GRLGSSLNEFARSLPQYRGMMLEKMRDLQEFALHFNIEFSVDDIMKYVDPSMAMNFVTRLLSHLSGAMTSTFLLLMTVVF
MLFEVERMPYKVQLMFDNPEKGNAILKRALNGVTHYLVIKTIISIATGIVIWLFLAAMGVRFAFLWGLLAFVLNYIPNIG
SVLAAIPPIIQALLFNGFADAFAVTGGYILINLIGGNIIDPRMMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTII
AKIVLELTPAGYRFAVLLSDGKPAKVEEEQAL
>Mature_351_residues
TTPVVSNQGLRLVAMLAMLVVIMAGIKAASPIVVPFLLAIFLAIVLNPLVKLLERIKIPRTLAVILLVTIIILLMVLLFG
RLGSSLNEFARSLPQYRGMMLEKMRDLQEFALHFNIEFSVDDIMKYVDPSMAMNFVTRLLSHLSGAMTSTFLLLMTVVFM
LFEVERMPYKVQLMFDNPEKGNAILKRALNGVTHYLVIKTIISIATGIVIWLFLAAMGVRFAFLWGLLAFVLNYIPNIGS
VLAAIPPIIQALLFNGFADAFAVTGGYILINLIGGNIIDPRMMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIA
KIVLELTPAGYRFAVLLSDGKPAKVEEEQAL

Specific function: Controls the transport of the quorum-sensing signal AI-2 either by enhancing its secretion or inhibiting its uptake and consequently represses biofilm formation and motility and affects the global gene expression in biofilms [H]

COG id: COG0628

COG function: function code R; Predicted permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0118 (perM) family [H]

Homologues:

Organism=Escherichia coli, GI1787885, Length=340, Percent_Identity=60, Blast_Score=376, Evalue=1e-105,
Organism=Escherichia coli, GI87082271, Length=345, Percent_Identity=48.1159420289855, Blast_Score=328, Evalue=3e-91,
Organism=Escherichia coli, GI1788838, Length=342, Percent_Identity=28.3625730994152, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002549 [H]

Pfam domain/function: PF01594 UPF0118 [H]

EC number: NA

Molecular weight: Translated: 38767; Mature: 38636

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPVVSNQGLRLVAMLAMLVVIMAGIKAASPIVVPFLLAIFLAIVLNPLVKLLERIKIP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RTLAVILLVTIIILLMVLLFGRLGSSLNEFARSLPQYRGMMLEKMRDLQEFALHFNIEFS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEC
VDDIMKYVDPSMAMNFVTRLLSHLSGAMTSTFLLLMTVVFMLFEVERMPYKVQLMFDNPE
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
KGNAILKRALNGVTHYLVIKTIISIATGIVIWLFLAAMGVRFAFLWGLLAFVLNYIPNIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
SVLAAIPPIIQALLFNGFADAFAVTGGYILINLIGGNIIDPRMMGRGLGLSTLVVFLSLI
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCCCHHHHHCCCCHHHHHHHHHHH
FWGWLLGPVGMLLSVPLTIIAKIVLELTPAGYRFAVLLSDGKPAKVEEEQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHCCC
>Mature Secondary Structure 
TTPVVSNQGLRLVAMLAMLVVIMAGIKAASPIVVPFLLAIFLAIVLNPLVKLLERIKIP
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RTLAVILLVTIIILLMVLLFGRLGSSLNEFARSLPQYRGMMLEKMRDLQEFALHFNIEFS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEC
VDDIMKYVDPSMAMNFVTRLLSHLSGAMTSTFLLLMTVVFMLFEVERMPYKVQLMFDNPE
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
KGNAILKRALNGVTHYLVIKTIISIATGIVIWLFLAAMGVRFAFLWGLLAFVLNYIPNIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
SVLAAIPPIIQALLFNGFADAFAVTGGYILINLIGGNIIDPRMMGRGLGLSTLVVFLSLI
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCCCHHHHHCCCCHHHHHHHHHHH
FWGWLLGPVGMLLSVPLTIIAKIVLELTPAGYRFAVLLSDGKPAKVEEEQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]