Click here to switch to the map view.

The map label for this gene is nagB [H]

Identifier: 108811276

GI number: 108811276

Start: 1278413

End: 1279213

Strand: Reverse

Name: nagB [H]

Synonym: YPN_1113

Alternate gene names: 108811276

Gene position: 1279213-1278413 (Counterclockwise)

Preceding gene: 108811283

Following gene: 108811275

Centisome position: 28.21

GC content: 47.07

Gene sequence:

>801_bases
ATGAGACTTATCCCACTGAGAAATACTGCCGAAGTTGGTAAATGGGCCGCTCGCCATATAGTGAATCGCATCAATGCGTT
TAAACCCACTGCCGAACGTCCGTTTATTCTGGGCCTGCCAACAGGCGGCACACCAATGGAGGCATATAAGTATTTGATTG
CGATGCATAAAGCGGGCGAGGTCAGCTTCAAGCATGTGGTGACATTTAACATGGATGAGTACGTTGGCTTGCCGAAAGAA
CATCCAGAAAGCTACTACACCTTCATGCACACTAATTTCTTTGATCACGTTGATATCCCGGCTGAAAACATCAATCTGTT
AAATGGTAACGCAGCGGATATCGATGCAGAATGCCGCCGTTATGAAGAAAAAATTAAGTCTTACGGTAAAATTCACCTGT
TCATGGGCGGCGTAGGGGTAGATGGCCATATCGCCTTTAATGAACCAGCGTCTTCTCTGGCATCACGTACCCGCATCAAA
ACCCTGACACAAGAAACCCGCATAGCGAACTCCCGTTTCTTTGGGGGTGATGCAAATCTCGTGCCTAAATATGCATTGAC
GGTTGGGGTGGGGACGTTGCTTGATGCAGAGGAAGTGATGATTCTGGTGACCGGCCATGGTAAAGCACAAGCTTTGCAAG
CCGCCGTTGAAGGGAGCATCAACCACATGTGGACTATCAGTTGCCTGCAACTTCATGCCAAAGCCATCATGGTGTGCGAT
GAACCTTCCACGATGGAACTGAAAGTCAAAACCGTGAAATATTTCCGCGAATTAGAAGCTGAAAACGTAAAAGATCTTTA
A

Upstream 100 bases:

>100_bases
CAGAATCTGAGTTACGCTTAGCTGGATGATTCAAACCGCGTTAAGCATAGCCACTTTTAGCAATCAAAATAGCCACTATT
AGCAATCAAAGAGGTGCACG

Downstream 100 bases:

>100_bases
TGACTATTAGGGGGCTCAGATGTACGCTTTAACTCACGGCCGTATTTATACCAGCCATGAAGTACTGGATAATCATGCTG
TTGTCGTTGCTGATGGATTG

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MRLIPLRNTAEVGKWAARHIVNRINAFKPTAERPFILGLPTGGTPMEAYKYLIAMHKAGEVSFKHVVTFNMDEYVGLPKE
HPESYYTFMHTNFFDHVDIPAENINLLNGNAADIDAECRRYEEKIKSYGKIHLFMGGVGVDGHIAFNEPASSLASRTRIK
TLTQETRIANSRFFGGDANLVPKYALTVGVGTLLDAEEVMILVTGHGKAQALQAAVEGSINHMWTISCLQLHAKAIMVCD
EPSTMELKVKTVKYFRELEAENVKDL

Sequences:

>Translated_266_residues
MRLIPLRNTAEVGKWAARHIVNRINAFKPTAERPFILGLPTGGTPMEAYKYLIAMHKAGEVSFKHVVTFNMDEYVGLPKE
HPESYYTFMHTNFFDHVDIPAENINLLNGNAADIDAECRRYEEKIKSYGKIHLFMGGVGVDGHIAFNEPASSLASRTRIK
TLTQETRIANSRFFGGDANLVPKYALTVGVGTLLDAEEVMILVTGHGKAQALQAAVEGSINHMWTISCLQLHAKAIMVCD
EPSTMELKVKTVKYFRELEAENVKDL
>Mature_266_residues
MRLIPLRNTAEVGKWAARHIVNRINAFKPTAERPFILGLPTGGTPMEAYKYLIAMHKAGEVSFKHVVTFNMDEYVGLPKE
HPESYYTFMHTNFFDHVDIPAENINLLNGNAADIDAECRRYEEKIKSYGKIHLFMGGVGVDGHIAFNEPASSLASRTRIK
TLTQETRIANSRFFGGDANLVPKYALTVGVGTLLDAEEVMILVTGHGKAQALQAAVEGSINHMWTISCLQLHAKAIMVCD
EPSTMELKVKTVKYFRELEAENVKDL

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=258, Percent_Identity=59.6899224806201, Blast_Score=329, Evalue=1e-90,
Organism=Homo sapiens, GI19923881, Length=258, Percent_Identity=59.6899224806201, Blast_Score=326, Evalue=1e-89,
Organism=Escherichia coli, GI1786893, Length=266, Percent_Identity=85.7142857142857, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI48994958, Length=240, Percent_Identity=28.75, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789530, Length=234, Percent_Identity=26.4957264957265, Blast_Score=84, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17554876, Length=258, Percent_Identity=56.5891472868217, Blast_Score=296, Evalue=6e-81,
Organism=Drosophila melanogaster, GI24581960, Length=256, Percent_Identity=59.375, Blast_Score=337, Evalue=4e-93,
Organism=Drosophila melanogaster, GI19920764, Length=256, Percent_Identity=59.375, Blast_Score=337, Evalue=4e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 29668; Mature: 29668

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIPLRNTAEVGKWAARHIVNRINAFKPTAERPFILGLPTGGTPMEAYKYLIAMHKAGE
CEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCC
VSFKHVVTFNMDEYVGLPKEHPESYYTFMHTNFFDHVDIPAENINLLNGNAADIDAECRR
CEEEEEEEECHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHH
YEEKIKSYGKIHLFMGGVGVDGHIAFNEPASSLASRTRIKTLTQETRIANSRFFGGDANL
HHHHHHCCCEEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
VPKYALTVGVGTLLDAEEVMILVTGHGKAQALQAAVEGSINHMWTISCLQLHAKAIMVCD
CCHHHHEECHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEHHHHHHHCEEEEEEC
EPSTMELKVKTVKYFRELEAENVKDL
CCCCEEEEHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRLIPLRNTAEVGKWAARHIVNRINAFKPTAERPFILGLPTGGTPMEAYKYLIAMHKAGE
CEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCC
VSFKHVVTFNMDEYVGLPKEHPESYYTFMHTNFFDHVDIPAENINLLNGNAADIDAECRR
CEEEEEEEECHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHH
YEEKIKSYGKIHLFMGGVGVDGHIAFNEPASSLASRTRIKTLTQETRIANSRFFGGDANL
HHHHHHCCCEEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
VPKYALTVGVGTLLDAEEVMILVTGHGKAQALQAAVEGSINHMWTISCLQLHAKAIMVCD
CCHHHHEECHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEHHHHHHHCEEEEEEC
EPSTMELKVKTVKYFRELEAENVKDL
CCCCEEEEHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA