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The map label for this gene is lnt [H]

Identifier: 108811265

GI number: 108811265

Start: 1264410

End: 1265996

Strand: Reverse

Name: lnt [H]

Synonym: YPN_1101

Alternate gene names: 108811265

Gene position: 1265996-1264410 (Counterclockwise)

Preceding gene: 108811266

Following gene: 108811264

Centisome position: 27.92

GC content: 50.85

Gene sequence:

>1587_bases
ATGATGCTCCGCAACCTAAACTGGAAGAATAAATTCTTGATGTCTATTGCTCTATTCCTCCAACGCCAGTGGGTTCGCGC
CCTACTGGCGCTATTTTTTGGTGCCTGTGGCACGCTTGCTTACTCGCCGTTTGATCATTGGCCTGCCGCCATTGTTTCAC
TATTCGGTTTGCTCAGTCTGACGTTGAACCGCACCACCAAACAAGCCACCTTCATTGGTTTTTGTTGGGGGATGGGGCTA
TTTGGCAGTGGCATCAACTGGGTGTATGTCAGCATCTCCGAATTTGGGGGTATGCCAACGGCAATCAATATCGTCCTCGT
CATCTTGCTAGCAGCATATTTATCACTCTACACCATGCTATTCGCCGGTTTATTAGCCCGCCTGTGCCCTAAGGCTACCT
GGTGGCGGCTCGCGATTGCGGCCCCGGTACTCTGGCAATTAACTGAATTCCTACGTGGCTGGGTATTAACGGGTTTCCCG
TGGTTACAATTCGGCTACAGCCAAATTAACGGCCCTCTGCGAGGGATAGCTCCCCTCCTCGGTGTTGATGGCATCACATT
TATCTTGATGGCTATCAGTGGCTTGCTGGTCTACGCCTGCTATCAACGTCGTATTGTCGCAGCAATTATCGCGCTGGCCT
TACTGCTGCTGCCCTGGCCACTGCGCCAAATACAGTGGTTCACACCAGAGCCTGAAAGAGCAGTCAATATCGCCATGGTA
CAAGGCAATATTGCTCAGTCAATGAAGTGGGATCCCAAAGCCCTGATCACCACATTGCAAATTTATCTTGATGAAACCCG
GCCATTTATGGGCAAAGCCCCCATTATTATCTGGCCAGAATCAGCTATTCCCGATATTGAAACCGATCAGAACACCTTCC
TGACAATGATAGATGGCCTGATGCGGGCAAATCATAGCAGCCTGATCACCGGCATTGTAGATGCCAAGCGGCAACCCGAG
GGGCAAGGGTATCAATTCTTTAACAGCATCATTGTGTTAGGCGATAAAGATACCTATCAATACCCGACCCGCAACCGTTA
TAGCAAACATCACTTGGTGCCCTTCGGTGAGTACGTACCGCTCGAGTCCCTACTGCGCCCGCTGGCTCCGTTATTTAATT
TACCCATGTCTTCATTTAACCGGGGTGATTATGTTCAACCCCCACTCACTATCGCTGGATTTAACCTCACGGCGGCTATT
TGTTATGAAATCGTCTTGGGCCAGCAAGTACGGGATAACTTCCGCCCTGAAACAGATTTTCTACTGACTATCTCCAATGA
TGCCTGGTTTGGTCACTCCATTGGGCCGTGGCAACATTTCCAAATGGCACGTATGCGCGCACTGGAGCTGGGCCGCCCGC
TACTGCGCAGCACCAATAATGGCATTACTGCCGCTATTGGCCCAAGTGGTGAAATTCTGGCGCAGATCCCACAGTTCACT
CAACAGGTTCTAGAGGTCAAGGTCACCCCAACCACCGGTATCACGCCATATGCCCGTTTTGGCTCATGGCCAATGTGGAT
TATTACTCTGGTTTTGGGCGCCTTTACCCTGTACTGCGCAATCCGGGGGCGCTCTGATAAGCACTAA

Upstream 100 bases:

>100_bases
TTACCTGCCCGTGGTGAAACGATTGAAATTGAAGGTTACTTATTTAAAGTTGCCATGGCAGATAGTCGACGTATCATTCA
GGTTCATGTAAAAATCCCGG

Downstream 100 bases:

>100_bases
TTTATGATCAGTACTAATTGATGATAAGCCTTGGTCAACTTGCCATAAACATTGGCTAACCTGTTATAAAAACGGGCTAA
TTTGCTATAAGCATCGATAG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MMLRNLNWKNKFLMSIALFLQRQWVRALLALFFGACGTLAYSPFDHWPAAIVSLFGLLSLTLNRTTKQATFIGFCWGMGL
FGSGINWVYVSISEFGGMPTAINIVLVILLAAYLSLYTMLFAGLLARLCPKATWWRLAIAAPVLWQLTEFLRGWVLTGFP
WLQFGYSQINGPLRGIAPLLGVDGITFILMAISGLLVYACYQRRIVAAIIALALLLLPWPLRQIQWFTPEPERAVNIAMV
QGNIAQSMKWDPKALITTLQIYLDETRPFMGKAPIIIWPESAIPDIETDQNTFLTMIDGLMRANHSSLITGIVDAKRQPE
GQGYQFFNSIIVLGDKDTYQYPTRNRYSKHHLVPFGEYVPLESLLRPLAPLFNLPMSSFNRGDYVQPPLTIAGFNLTAAI
CYEIVLGQQVRDNFRPETDFLLTISNDAWFGHSIGPWQHFQMARMRALELGRPLLRSTNNGITAAIGPSGEILAQIPQFT
QQVLEVKVTPTTGITPYARFGSWPMWIITLVLGAFTLYCAIRGRSDKH

Sequences:

>Translated_528_residues
MMLRNLNWKNKFLMSIALFLQRQWVRALLALFFGACGTLAYSPFDHWPAAIVSLFGLLSLTLNRTTKQATFIGFCWGMGL
FGSGINWVYVSISEFGGMPTAINIVLVILLAAYLSLYTMLFAGLLARLCPKATWWRLAIAAPVLWQLTEFLRGWVLTGFP
WLQFGYSQINGPLRGIAPLLGVDGITFILMAISGLLVYACYQRRIVAAIIALALLLLPWPLRQIQWFTPEPERAVNIAMV
QGNIAQSMKWDPKALITTLQIYLDETRPFMGKAPIIIWPESAIPDIETDQNTFLTMIDGLMRANHSSLITGIVDAKRQPE
GQGYQFFNSIIVLGDKDTYQYPTRNRYSKHHLVPFGEYVPLESLLRPLAPLFNLPMSSFNRGDYVQPPLTIAGFNLTAAI
CYEIVLGQQVRDNFRPETDFLLTISNDAWFGHSIGPWQHFQMARMRALELGRPLLRSTNNGITAAIGPSGEILAQIPQFT
QQVLEVKVTPTTGITPYARFGSWPMWIITLVLGAFTLYCAIRGRSDKH
>Mature_528_residues
MMLRNLNWKNKFLMSIALFLQRQWVRALLALFFGACGTLAYSPFDHWPAAIVSLFGLLSLTLNRTTKQATFIGFCWGMGL
FGSGINWVYVSISEFGGMPTAINIVLVILLAAYLSLYTMLFAGLLARLCPKATWWRLAIAAPVLWQLTEFLRGWVLTGFP
WLQFGYSQINGPLRGIAPLLGVDGITFILMAISGLLVYACYQRRIVAAIIALALLLLPWPLRQIQWFTPEPERAVNIAMV
QGNIAQSMKWDPKALITTLQIYLDETRPFMGKAPIIIWPESAIPDIETDQNTFLTMIDGLMRANHSSLITGIVDAKRQPE
GQGYQFFNSIIVLGDKDTYQYPTRNRYSKHHLVPFGEYVPLESLLRPLAPLFNLPMSSFNRGDYVQPPLTIAGFNLTAAI
CYEIVLGQQVRDNFRPETDFLLTISNDAWFGHSIGPWQHFQMARMRALELGRPLLRSTNNGITAAIGPSGEILAQIPQFT
QQVLEVKVTPTTGITPYARFGSWPMWIITLVLGAFTLYCAIRGRSDKH

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=511, Percent_Identity=65.1663405088063, Blast_Score=700, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 59363; Mature: 59363

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLRNLNWKNKFLMSIALFLQRQWVRALLALFFGACGTLAYSPFDHWPAAIVSLFGLLSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TLNRTTKQATFIGFCWGMGLFGSGINWVYVSISEFGGMPTAINIVLVILLAAYLSLYTML
HHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FAGLLARLCPKATWWRLAIAAPVLWQLTEFLRGWVLTGFPWLQFGYSQINGPLRGIAPLL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHH
GVDGITFILMAISGLLVYACYQRRIVAAIIALALLLLPWPLRQIQWFTPEPERAVNIAMV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCEECCCCCCCCEEEEEE
QGNIAQSMKWDPKALITTLQIYLDETRPFMGKAPIIIWPESAIPDIETDQNTFLTMIDGL
ECCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHH
MRANHSSLITGIVDAKRQPEGQGYQFFNSIIVLGDKDTYQYPTRNRYSKHHLVPFGEYVP
HHCCCHHHHHHHHHHCCCCCCCCCEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
LESLLRPLAPLFNLPMSSFNRGDYVQPPLTIAGFNLTAAICYEIVLGQQVRDNFRPETDF
HHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCE
LLTISNDAWFGHSIGPWQHFQMARMRALELGRPLLRSTNNGITAAIGPSGEILAQIPQFT
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECCCHHHHHHHHHHH
QQVLEVKVTPTTGITPYARFGSWPMWIITLVLGAFTLYCAIRGRSDKH
HHHHEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMLRNLNWKNKFLMSIALFLQRQWVRALLALFFGACGTLAYSPFDHWPAAIVSLFGLLSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TLNRTTKQATFIGFCWGMGLFGSGINWVYVSISEFGGMPTAINIVLVILLAAYLSLYTML
HHCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FAGLLARLCPKATWWRLAIAAPVLWQLTEFLRGWVLTGFPWLQFGYSQINGPLRGIAPLL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHH
GVDGITFILMAISGLLVYACYQRRIVAAIIALALLLLPWPLRQIQWFTPEPERAVNIAMV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCEECCCCCCCCEEEEEE
QGNIAQSMKWDPKALITTLQIYLDETRPFMGKAPIIIWPESAIPDIETDQNTFLTMIDGL
ECCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHH
MRANHSSLITGIVDAKRQPEGQGYQFFNSIIVLGDKDTYQYPTRNRYSKHHLVPFGEYVP
HHCCCHHHHHHHHHHCCCCCCCCCEEECCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
LESLLRPLAPLFNLPMSSFNRGDYVQPPLTIAGFNLTAAICYEIVLGQQVRDNFRPETDF
HHHHHHHHHHHHHCCHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCE
LLTISNDAWFGHSIGPWQHFQMARMRALELGRPLLRSTNNGITAAIGPSGEILAQIPQFT
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECCCHHHHHHHHHHH
QQVLEVKVTPTTGITPYARFGSWPMWIITLVLGAFTLYCAIRGRSDKH
HHHHEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]