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The map label for this gene is cutL [H]

Identifier: 108797471

GI number: 108797471

Start: 546301

End: 548691

Strand: Direct

Name: cutL [H]

Synonym: Mmcs_0491

Alternate gene names: 108797471

Gene position: 546301-548691 (Clockwise)

Preceding gene: 108797470

Following gene: 108797472

Centisome position: 9.58

GC content: 67.75

Gene sequence:

>2391_bases
ATGACCGCGGTGGACGAACGCCCGGACGCGCAGGCGGACAACGACAGGAAACCGTGCGGTTACGGCCGGATGCTGCGCAA
GGAGGATCCGCGCTTCGTCCGCGGCCGGGGCAACTACGTCGACGACGTCACGCTGCCCGGCATGCTGCACCTGGCGATCC
TGCGCTCACCGTATGCCCATGCGCGGATCGCGAACATCGACATCTCGGCCGCGGAGGCGCATCCGAAGGTCAAGGCGGTC
GTCACCGGCGCCGACCTGGCGGAGAAGGGCCTGGCCTGGATGCCGACCCTGTCCAACGACGTGCAGGCCGTCCTCGCCAC
CGACAAGGTGCGATTCCAGGGGCAGGAGGTGGCATTCGTCGTCGCCGAGGACCGGTATTCGGCTCGTGACGGTGTCGAGT
TGATCGACGTCGACTATGAGCCTCTCGACCCGGTCATCGACGTCCGCCGGGCACTGGATCCCGACGCGGCGGTGATCCGC
ACCGACCTCGACGGTAAGACCGACAACCACTGCTTCGACTGGGAGACCGGCGACGCCGCCGCCACCGACGCGGCGTTCGC
CAAGGCCGACGTCGTGGTCAAACAGGAGATGGTCTATCCGCGTGTGCATCCCGCGCCGATGGAGACCTGCGGCGCGGTCG
CCGACCTCGACCCGGTCAGCGGCAAGCTCACCCTGTGGTCGACCACGCAGGCGCCGCACGCACACCGCACCCTCTACGCC
CTGGTGGCCGGGCTGCCCGAACACAAGATCCGGGTCATCTCACCGGACATCGGCGGCGGCTTCGGCAACAAGGTGCCGAT
CTATCCGGGATACGTCTGCGCCATCGTGGGTTCGCTGCTGCTGGGTAAGCCGGTCAAGTGGATGGAGGACCGCAGCGAGA
ACCTGACCTCGACCGGATTCGCCCGGGACTACATCATGGTCGGCGAGATCGCCGCCACGTCCGACGGCAAGATCCTGGCC
GTCCGCTCCAACGTGCTGGCCGACCACGGTGCATTCAACGGCGTTGCGGCGCCGACGAAGTACCCCGCGGGCTTCTTCGG
GGTGTTCACCGGCAGCTACGACCTCGAGGCCGCGTACTGCCACATGACCGCGGTCTACACCAACAAGGCGCCCGGCGGCG
TGGCCTACGCGTGTTCGTTCCGGATCACCGAGGCGGTGTACTTCGTCGAGCGGTTGGTGGACTGTCTGGCCTACGAGATG
AAGATGGACCCGGCCGACCTGCGGCTGCGGAACCTGCTGAAACCCGACCAGTTCCCGTACCACTCGAAAACCGGCTGGAC
CTACGACTCCGGCGACTACGAGACCACCATGCGCAAGGCCATGGACATGATCGGCTACGAGCAGTTGCGCGCCGAGCAGG
CCGCCAAGCGGGAGCGCGGTGAGCTGATGGGGATCGGCATGGCGTTCTTCACCGAGGCCGTCGGCGCCGGACCGCGCAAG
GACATGGACATTCTGGGACTCGGCATGGCCGACGGCTGTGAACTGCGGGTGCATCCCACCGGCAAGGCCGTGGTCCGGTT
GTCGGTGCAGACCCAGGGGCAGGGCCACGAAACCACCTTCGCGCAGATCGTCGCCGAGGAGTTGGGGATCCCACCCGACG
ACATCGACGTGGTGCACGGCGACACCGACCAGACGCCGTTCGGGCTGGGCACCTACGGCAGCCGTTCGACCCCCGTATCC
GGTGCCGCGGCCGCGTTGGTCGCGCGCAAGGTGCGGGACAAGGCCAAGATCATCGCCTCGGGGATGTTGGAGGCGTCAGT
CGCCGACCTCGAATGGGACAAGGGCGCCTTCCACGTCAAGGGTGACCCGGCGGCGTCGGTCACCATCCAGGACATCGCGA
TGCGCGCGCACGGCGCCGGTGACCTCCCGGAGGGCATCGAGGGCGGCCTGGACGCCCAGATCTGTTACAACCCCGAGAAT
CTCACCTATCCGTACGGCGCCTACTTCTGCGTGGTCGACGTCGATCCGGGCACCGCGGTGGTCAAGGTCCGGCGGTTCCT
CGCGGTCGACGACTGTGGCACGCGGATCAACCCGATGATCATCGAGGGTCAGGTGCACGGCGGCATCGTCGACGGGATCG
GGATGGCGCTGATGGAGATGATCGCGTTCGACGAGGAAGGCAACTGCCTCGGCGGGTCGCTGATGGACTATCTGATCCCC
ACCGCGCTCGAGGTGCCGGAGCTGGAGACCGGTCATACCGTCACGCCGTCCCCGCACCACCCGATCGGCGCCAAGGGCAT
CGGGGAGTCCGCCACCGTCGGCTCACCCCCCGCGGTGGTGAACGCCGTCGTCGATGCGTTGGCGCCGTTCGGAATCCGGC
ACGCCGACTTGCCGCTGACCCCCTCCCGGGTGTGGGAGGCCATGCAGGGCCGGCCCACCCCGCCGATCTGA

Upstream 100 bases:

>100_bases
AATCAGGCCCGTCCGCAACGGATTTCGCACCGCAGTCCCAGACCGACGACACCCTCGGCCCGGTGGCCGGTGACCATCTC
ATCGAGACAGGAAGCCCATC

Downstream 100 bases:

>100_bases
TCATGAGGTCCGCCGACACCATGCACGACCGCGCGCAGCAACTGCTGCAGACGCGCATCCCGTTCGTCCGCGCCACCGTG
GTGCGGGCCCAGCAGCCGAC

Product: carbon monoxide dehydrogenase, large subunit apoprotein

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 796; Mature: 795

Protein sequence:

>796_residues
MTAVDERPDAQADNDRKPCGYGRMLRKEDPRFVRGRGNYVDDVTLPGMLHLAILRSPYAHARIANIDISAAEAHPKVKAV
VTGADLAEKGLAWMPTLSNDVQAVLATDKVRFQGQEVAFVVAEDRYSARDGVELIDVDYEPLDPVIDVRRALDPDAAVIR
TDLDGKTDNHCFDWETGDAAATDAAFAKADVVVKQEMVYPRVHPAPMETCGAVADLDPVSGKLTLWSTTQAPHAHRTLYA
LVAGLPEHKIRVISPDIGGGFGNKVPIYPGYVCAIVGSLLLGKPVKWMEDRSENLTSTGFARDYIMVGEIAATSDGKILA
VRSNVLADHGAFNGVAAPTKYPAGFFGVFTGSYDLEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAYEM
KMDPADLRLRNLLKPDQFPYHSKTGWTYDSGDYETTMRKAMDMIGYEQLRAEQAAKRERGELMGIGMAFFTEAVGAGPRK
DMDILGLGMADGCELRVHPTGKAVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIDVVHGDTDQTPFGLGTYGSRSTPVS
GAAAALVARKVRDKAKIIASGMLEASVADLEWDKGAFHVKGDPAASVTIQDIAMRAHGAGDLPEGIEGGLDAQICYNPEN
LTYPYGAYFCVVDVDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMIAFDEEGNCLGGSLMDYLIP
TALEVPELETGHTVTPSPHHPIGAKGIGESATVGSPPAVVNAVVDALAPFGIRHADLPLTPSRVWEAMQGRPTPPI

Sequences:

>Translated_796_residues
MTAVDERPDAQADNDRKPCGYGRMLRKEDPRFVRGRGNYVDDVTLPGMLHLAILRSPYAHARIANIDISAAEAHPKVKAV
VTGADLAEKGLAWMPTLSNDVQAVLATDKVRFQGQEVAFVVAEDRYSARDGVELIDVDYEPLDPVIDVRRALDPDAAVIR
TDLDGKTDNHCFDWETGDAAATDAAFAKADVVVKQEMVYPRVHPAPMETCGAVADLDPVSGKLTLWSTTQAPHAHRTLYA
LVAGLPEHKIRVISPDIGGGFGNKVPIYPGYVCAIVGSLLLGKPVKWMEDRSENLTSTGFARDYIMVGEIAATSDGKILA
VRSNVLADHGAFNGVAAPTKYPAGFFGVFTGSYDLEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAYEM
KMDPADLRLRNLLKPDQFPYHSKTGWTYDSGDYETTMRKAMDMIGYEQLRAEQAAKRERGELMGIGMAFFTEAVGAGPRK
DMDILGLGMADGCELRVHPTGKAVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIDVVHGDTDQTPFGLGTYGSRSTPVS
GAAAALVARKVRDKAKIIASGMLEASVADLEWDKGAFHVKGDPAASVTIQDIAMRAHGAGDLPEGIEGGLDAQICYNPEN
LTYPYGAYFCVVDVDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMIAFDEEGNCLGGSLMDYLIP
TALEVPELETGHTVTPSPHHPIGAKGIGESATVGSPPAVVNAVVDALAPFGIRHADLPLTPSRVWEAMQGRPTPPI
>Mature_795_residues
TAVDERPDAQADNDRKPCGYGRMLRKEDPRFVRGRGNYVDDVTLPGMLHLAILRSPYAHARIANIDISAAEAHPKVKAVV
TGADLAEKGLAWMPTLSNDVQAVLATDKVRFQGQEVAFVVAEDRYSARDGVELIDVDYEPLDPVIDVRRALDPDAAVIRT
DLDGKTDNHCFDWETGDAAATDAAFAKADVVVKQEMVYPRVHPAPMETCGAVADLDPVSGKLTLWSTTQAPHAHRTLYAL
VAGLPEHKIRVISPDIGGGFGNKVPIYPGYVCAIVGSLLLGKPVKWMEDRSENLTSTGFARDYIMVGEIAATSDGKILAV
RSNVLADHGAFNGVAAPTKYPAGFFGVFTGSYDLEAAYCHMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAYEMK
MDPADLRLRNLLKPDQFPYHSKTGWTYDSGDYETTMRKAMDMIGYEQLRAEQAAKRERGELMGIGMAFFTEAVGAGPRKD
MDILGLGMADGCELRVHPTGKAVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIDVVHGDTDQTPFGLGTYGSRSTPVSG
AAAALVARKVRDKAKIIASGMLEASVADLEWDKGAFHVKGDPAASVTIQDIAMRAHGAGDLPEGIEGGLDAQICYNPENL
TYPYGAYFCVVDVDPGTAVVKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMIAFDEEGNCLGGSLMDYLIPT
ALEVPELETGHTVTPSPHHPIGAKGIGESATVGSPPAVVNAVVDALAPFGIRHADLPLTPSRVWEAMQGRPTPPI

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=789, Percent_Identity=23.9543726235741, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI91823271, Length=794, Percent_Identity=21.9143576826196, Blast_Score=109, Evalue=1e-23,
Organism=Escherichia coli, GI1789230, Length=771, Percent_Identity=30.7392996108949, Blast_Score=259, Evalue=5e-70,
Organism=Escherichia coli, GI1789246, Length=805, Percent_Identity=27.7018633540373, Blast_Score=230, Evalue=3e-61,
Organism=Escherichia coli, GI1786478, Length=746, Percent_Identity=25.4691689008043, Blast_Score=129, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17540638, Length=792, Percent_Identity=22.7272727272727, Blast_Score=132, Evalue=9e-31,
Organism=Drosophila melanogaster, GI17737937, Length=755, Percent_Identity=23.9735099337748, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24647193, Length=766, Percent_Identity=22.1932114882507, Blast_Score=86, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 85486; Mature: 85355

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVDERPDAQADNDRKPCGYGRMLRKEDPRFVRGRGNYVDDVTLPGMLHLAILRSPYAH
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCHH
ARIANIDISAAEAHPKVKAVVTGADLAEKGLAWMPTLSNDVQAVLATDKVRFQGQEVAFV
EEEEEEEEECCCCCCCEEEEEECCHHHHCCCEECCCCCCCCEEEEEECCEEECCCEEEEE
VAEDRYSARDGVELIDVDYEPLDPVIDVRRALDPDAAVIRTDLDGKTDNHCFDWETGDAA
EECCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCCCCC
ATDAAFAKADVVVKQEMVYPRVHPAPMETCGAVADLDPVSGKLTLWSTTQAPHAHRTLYA
HHHHHHHHHHHEEHHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
LVAGLPEHKIRVISPDIGGGFGNKVPIYPGYVCAIVGSLLLGKPVKWMEDRSENLTSTGF
HHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCC
ARDYIMVGEIAATSDGKILAVRSNVLADHGAFNGVAAPTKYPAGFFGVFTGSYDLEAAYC
CCCEEEEEEEEECCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEE
HMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAYEMKMDPADLRLRNLLKPDQFPY
EEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
HSKTGWTYDSGDYETTMRKAMDMIGYEQLRAEQAAKRERGELMGIGMAFFTEAVGAGPRK
CCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCC
DMDILGLGMADGCELRVHPTGKAVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIDVVHG
CCEEEEECCCCCCEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEC
DTDQTPFGLGTYGSRSTPVSGAAAALVARKVRDKAKIIASGMLEASVADLEWDKGAFHVK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
GDPAASVTIQDIAMRAHGAGDLPEGIEGGLDAQICYNPENLTYPYGAYFCVVDVDPGTAV
CCCCCEEEHHHHHHHHCCCCCCCHHHCCCCCCEEEECCCCCCCCCCEEEEEEECCCCHHH
VKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMIAFDEEGNCLGGSLMDYLIP
HHHHHHHEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
TALEVPELETGHTVTPSPHHPIGAKGIGESATVGSPPAVVNAVVDALAPFGIRHADLPLT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
PSRVWEAMQGRPTPPI
HHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TAVDERPDAQADNDRKPCGYGRMLRKEDPRFVRGRGNYVDDVTLPGMLHLAILRSPYAH
CCCCCCCCCCCCCCCCCCCCCCHHCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCHH
ARIANIDISAAEAHPKVKAVVTGADLAEKGLAWMPTLSNDVQAVLATDKVRFQGQEVAFV
EEEEEEEEECCCCCCCEEEEEECCHHHHCCCEECCCCCCCCEEEEEECCEEECCCEEEEE
VAEDRYSARDGVELIDVDYEPLDPVIDVRRALDPDAAVIRTDLDGKTDNHCFDWETGDAA
EECCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCCCCC
ATDAAFAKADVVVKQEMVYPRVHPAPMETCGAVADLDPVSGKLTLWSTTQAPHAHRTLYA
HHHHHHHHHHHEEHHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
LVAGLPEHKIRVISPDIGGGFGNKVPIYPGYVCAIVGSLLLGKPVKWMEDRSENLTSTGF
HHHCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCC
ARDYIMVGEIAATSDGKILAVRSNVLADHGAFNGVAAPTKYPAGFFGVFTGSYDLEAAYC
CCCEEEEEEEEECCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEE
HMTAVYTNKAPGGVAYACSFRITEAVYFVERLVDCLAYEMKMDPADLRLRNLLKPDQFPY
EEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
HSKTGWTYDSGDYETTMRKAMDMIGYEQLRAEQAAKRERGELMGIGMAFFTEAVGAGPRK
CCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCC
DMDILGLGMADGCELRVHPTGKAVVRLSVQTQGQGHETTFAQIVAEELGIPPDDIDVVHG
CCEEEEECCCCCCEEEEECCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEC
DTDQTPFGLGTYGSRSTPVSGAAAALVARKVRDKAKIIASGMLEASVADLEWDKGAFHVK
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
GDPAASVTIQDIAMRAHGAGDLPEGIEGGLDAQICYNPENLTYPYGAYFCVVDVDPGTAV
CCCCCEEEHHHHHHHHCCCCCCCHHHCCCCCCEEEECCCCCCCCCCEEEEEEECCCCHHH
VKVRRFLAVDDCGTRINPMIIEGQVHGGIVDGIGMALMEMIAFDEEGNCLGGSLMDYLIP
HHHHHHHEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
TALEVPELETGHTVTPSPHHPIGAKGIGESATVGSPPAVVNAVVDALAPFGIRHADLPLT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
PSRVWEAMQGRPTPPI
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]