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The map label for this gene is cutS [H]

Identifier: 108797470

GI number: 108797470

Start: 545729

End: 546304

Strand: Direct

Name: cutS [H]

Synonym: Mmcs_0490

Alternate gene names: 108797470

Gene position: 545729-546304 (Clockwise)

Preceding gene: 108797469

Following gene: 108797471

Centisome position: 9.57

GC content: 67.88

Gene sequence:

>576_bases
ATGCAGGTGAGCATGACCGTCAACGGCGAGCAGGTGAGCGCCGATGTCGAACCGCGGATGCTGCTGGTGCACTTCCTGCG
AGACGAGTTGCGGCTCACCGGAACCCACTGGGGCTGTGATACCAGCAACTGCGGGACCTGCGTGGTGTCGCTCGACGGCG
AGCCCGTGAAGTCGTGCACGATGCTGGCCGTGATGGCCGACGGGCACGACGTCCGCACGGTGGAGGGCCTCGAGGTCGAC
GGAAAGCTCGACCCGGTTCAGGAGGGGTTCATGCAGTGCCACGGCCTGCAGTGCGGCTTCTGCACCCCGGGCATGATGAT
CACCGCCCGCGCCCTCCTGGACCGCAACCCCCACCCGACCGAACACGAGATCCGGGAGGCGATCTCCGGGCAGATCTGCC
GGTGCACGGGCTACACCACGATCGTGCGGTCGGTGCAGTGGGCCGCCGGGCACGCGCGGGGGCGGGACGTCGAATCAGGC
CCGTCCGCAACGGATTTCGCACCGCAGTCCCAGACCGACGACACCCTCGGCCCGGTGGCCGGTGACCATCTCATCGAGAC
AGGAAGCCCATCATGA

Upstream 100 bases:

>100_bases
ACATGCGGGGCAGCGCCGACTACAAGCGGCATCTCGCGTCCGAACTGACCGTCCGCAACCTACGCACCGCCGTGCGGCGC
GTCCGAGAAAGGGCCTGAGT

Downstream 100 bases:

>100_bases
CCGCGGTGGACGAACGCCCGGACGCGCAGGCGGACAACGACAGGAAACCGTGCGGTTACGGCCGGATGCTGCGCAAGGAG
GATCCGCGCTTCGTCCGCGG

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MQVSMTVNGEQVSADVEPRMLLVHFLRDELRLTGTHWGCDTSNCGTCVVSLDGEPVKSCTMLAVMADGHDVRTVEGLEVD
GKLDPVQEGFMQCHGLQCGFCTPGMMITARALLDRNPHPTEHEIREAISGQICRCTGYTTIVRSVQWAAGHARGRDVESG
PSATDFAPQSQTDDTLGPVAGDHLIETGSPS

Sequences:

>Translated_191_residues
MQVSMTVNGEQVSADVEPRMLLVHFLRDELRLTGTHWGCDTSNCGTCVVSLDGEPVKSCTMLAVMADGHDVRTVEGLEVD
GKLDPVQEGFMQCHGLQCGFCTPGMMITARALLDRNPHPTEHEIREAISGQICRCTGYTTIVRSVQWAAGHARGRDVESG
PSATDFAPQSQTDDTLGPVAGDHLIETGSPS
>Mature_191_residues
MQVSMTVNGEQVSADVEPRMLLVHFLRDELRLTGTHWGCDTSNCGTCVVSLDGEPVKSCTMLAVMADGHDVRTVEGLEVD
GKLDPVQEGFMQCHGLQCGFCTPGMMITARALLDRNPHPTEHEIREAISGQICRCTGYTTIVRSVQWAAGHARGRDVESG
PSATDFAPQSQTDDTLGPVAGDHLIETGSPS

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=148, Percent_Identity=39.8648648648649, Blast_Score=91, Evalue=4e-19,
Organism=Homo sapiens, GI91823271, Length=160, Percent_Identity=36.875, Blast_Score=84, Evalue=9e-17,
Organism=Escherichia coli, GI1786480, Length=168, Percent_Identity=36.3095238095238, Blast_Score=116, Evalue=8e-28,
Organism=Escherichia coli, GI1789232, Length=147, Percent_Identity=38.0952380952381, Blast_Score=105, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=42.9530201342282, Blast_Score=121, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=154, Percent_Identity=35.7142857142857, Blast_Score=107, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=154, Percent_Identity=35.0649350649351, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17737937, Length=152, Percent_Identity=38.1578947368421, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24647201, Length=156, Percent_Identity=32.6923076923077, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647199, Length=155, Percent_Identity=30.9677419354839, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647197, Length=162, Percent_Identity=31.4814814814815, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647195, Length=162, Percent_Identity=31.4814814814815, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24647193, Length=155, Percent_Identity=32.9032258064516, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 20525; Mature: 20525

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSMTVNGEQVSADVEPRMLLVHFLRDELRLTGTHWGCDTSNCGTCVVSLDGEPVKSCT
CEEEEEECCCEEECCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCCEE
MLAVMADGHDVRTVEGLEVDGKLDPVQEGFMQCHGLQCGFCTPGMMITARALLDRNPHPT
EEEEEECCCCEEEEECEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCC
EHEIREAISGQICRCTGYTTIVRSVQWAAGHARGRDVESGPSATDFAPQSQTDDTLGPVA
HHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GDHLIETGSPS
CCCEECCCCCC
>Mature Secondary Structure
MQVSMTVNGEQVSADVEPRMLLVHFLRDELRLTGTHWGCDTSNCGTCVVSLDGEPVKSCT
CEEEEEECCCEEECCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCCEE
MLAVMADGHDVRTVEGLEVDGKLDPVQEGFMQCHGLQCGFCTPGMMITARALLDRNPHPT
EEEEEECCCCEEEEECEEECCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCC
EHEIREAISGQICRCTGYTTIVRSVQWAAGHARGRDVESGPSATDFAPQSQTDDTLGPVA
HHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GDHLIETGSPS
CCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]