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The map label for this gene is ppe4 [H]

Identifier: 108797354

GI number: 108797354

Start: 419811

End: 421388

Strand: Direct

Name: ppe4 [H]

Synonym: Mmcs_0374

Alternate gene names: 108797354

Gene position: 419811-421388 (Clockwise)

Preceding gene: 108797353

Following gene: 108797356

Centisome position: 7.36

GC content: 73.26

Gene sequence:

>1578_bases
ATGGTTCCCCCCATCTGGATGGCCCTGCCACCCGAGGTGCACTCGGCGCTGCTGTCCAGCGGCCCCGGCCCCGGGTCGCT
GCTGGCCGCCGCGGGGGCGTGGCAGTCGCTGAGCGCCGAATATGCCTCGGCCGCAGCGGAGTTGACCGGCATACTCGGCT
CGGTGCAGGCCGGGGCGTGGGAAGGGCCCAGCGCCGAGCAGTACGTCGCCGCACACACCCCGTACCTCGCCTGGCTGGCG
CAGGCGAGTGCGAACAGCGCGGCGACGGCGGCGCAACACGAGACTGCGGCCGCCGCGTACACCACGGCGCTGGCCACCAT
GCCGACGCTGGGTGAGCTGGCCGCCAACCACGCCACCCACGCGGTGCTGCTGGCGACGAACTTCCTCGGCATCAACACGA
TTCCGATCGCCGTCAACGAGGCCGACTACGTGCGGATGTGGATTCAGGCCGCCACCAGCATGAGCACGTATCAGGCCGTC
GCCGGTGCCGCGGTGGCCGCCGCCCCGACCACGGCGCCGGCGCCGTATCTGCTGGCGCCGGGTGTCGGCGAGGCGGGCCA
GGCGATGGCGTCGGTTCAGCAGCTCGGCGCGCAGGCCCAGGCGAGTGAATCCGGTTCGGCGCTCAACATCTCCGACTCCA
TCAACCAGCTGCTCGAGCAGTACCTGCAGAGCGCGCCCGGCGGTCAGGAGATCATCGACTTCCTGCGGGACCCCCTGGGG
AACCTGCAGACGCTCATCAACGACTTCATGACCAACCCGTCGGCCGCGCTGGTGACGTGGGGGCCGCTGCTGTCGGCCGT
GGCCTACCAGGTCTTCACCAACCTGGTCGGGTGGCCGACGTGGGCGATGATCTTCGCATCGCCGTTCCTGCTCGCGGCCC
TCATCCCGCTCGGCATCGCCGGGCTGGTGCTGATCATCGACGCACTCAAACCCGAACTGACCCAACCGCCCGCGGAACAG
ACCGAACCGGCGCCCGCACCGGCCCCACGGCCCGACCAGCAGGTGCTGCCGGTGGCGGGCGTTCCCGCACCCGGTGCGCC
CGCCACTCCCGGAACGGCGCCGGCGGGCAGTTCGGCCGCCGCCCCGGCCGCACCCGCCCCCGCCGCGGCGGCAGCCGCCC
CACTGGTGCCCTACGCGGTTCGCGGTGGCGACCCGGGTGAGGGGTTCACGCCCACGGTGCGCGACTCGACCGGGGCCAAG
GCACCCGCCGGTGACATCCCGGCCGCCGCCGCGGCGGCGGCCGCCGCCTCGGCCGCGGAACGGCGAAAGCGACGGCGCCG
CAAGATCACCGAGGTCAAGGGCCGCGGCTACGCCGACGTGTACATGGACTACGAAGACGACCCCGACGAGCCGCCGATCG
TGGAGCCGCGGGTGGCGGCGTCCTCACGCGGCGCGGGTGCGATGGGCTTCACCGGTACCGCACCGGGTGCCGCCGATGCG
CGGGCGACGGGGTTGACGACGCTGTCCCCGGATGCGTTCGGCACCGGGCCGGTCAGCCCCATGCTGCCCGGCACGTGGAA
CCCCGACAGCGAGCCCGACCAGCCCGCAGAGGGCCAGGAGGGAGGACCGCGCACCTGA

Upstream 100 bases:

>100_bases
GGAGCTCGGCAGATCCGGCGTCGGTGTCGGCCAGTCCGGCGCCAGCTACGCCGCAGGCGATGCGATGAACGCATCGGCAT
ACATGATCGCCCGCGGTTAG

Downstream 100 bases:

>100_bases
ACAGACAGTCAGTGCCCCAACATCTTTCCGCGATCCGAAAGGACTCTCAATGAAGAAGTCAAGCCGCGGCGGTGACCGGG
GGTGAATCAGGTTGCCAGGT

Product: PPE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MVPPIWMALPPEVHSALLSSGPGPGSLLAAAGAWQSLSAEYASAAAELTGILGSVQAGAWEGPSAEQYVAAHTPYLAWLA
QASANSAATAAQHETAAAAYTTALATMPTLGELAANHATHAVLLATNFLGINTIPIAVNEADYVRMWIQAATSMSTYQAV
AGAAVAAAPTTAPAPYLLAPGVGEAGQAMASVQQLGAQAQASESGSALNISDSINQLLEQYLQSAPGGQEIIDFLRDPLG
NLQTLINDFMTNPSAALVTWGPLLSAVAYQVFTNLVGWPTWAMIFASPFLLAALIPLGIAGLVLIIDALKPELTQPPAEQ
TEPAPAPAPRPDQQVLPVAGVPAPGAPATPGTAPAGSSAAAPAAPAPAAAAAAPLVPYAVRGGDPGEGFTPTVRDSTGAK
APAGDIPAAAAAAAAASAAERRKRRRRKITEVKGRGYADVYMDYEDDPDEPPIVEPRVAASSRGAGAMGFTGTAPGAADA
RATGLTTLSPDAFGTGPVSPMLPGTWNPDSEPDQPAEGQEGGPRT

Sequences:

>Translated_525_residues
MVPPIWMALPPEVHSALLSSGPGPGSLLAAAGAWQSLSAEYASAAAELTGILGSVQAGAWEGPSAEQYVAAHTPYLAWLA
QASANSAATAAQHETAAAAYTTALATMPTLGELAANHATHAVLLATNFLGINTIPIAVNEADYVRMWIQAATSMSTYQAV
AGAAVAAAPTTAPAPYLLAPGVGEAGQAMASVQQLGAQAQASESGSALNISDSINQLLEQYLQSAPGGQEIIDFLRDPLG
NLQTLINDFMTNPSAALVTWGPLLSAVAYQVFTNLVGWPTWAMIFASPFLLAALIPLGIAGLVLIIDALKPELTQPPAEQ
TEPAPAPAPRPDQQVLPVAGVPAPGAPATPGTAPAGSSAAAPAAPAPAAAAAAPLVPYAVRGGDPGEGFTPTVRDSTGAK
APAGDIPAAAAAAAAASAAERRKRRRRKITEVKGRGYADVYMDYEDDPDEPPIVEPRVAASSRGAGAMGFTGTAPGAADA
RATGLTTLSPDAFGTGPVSPMLPGTWNPDSEPDQPAEGQEGGPRT
>Mature_525_residues
MVPPIWMALPPEVHSALLSSGPGPGSLLAAAGAWQSLSAEYASAAAELTGILGSVQAGAWEGPSAEQYVAAHTPYLAWLA
QASANSAATAAQHETAAAAYTTALATMPTLGELAANHATHAVLLATNFLGINTIPIAVNEADYVRMWIQAATSMSTYQAV
AGAAVAAAPTTAPAPYLLAPGVGEAGQAMASVQQLGAQAQASESGSALNISDSINQLLEQYLQSAPGGQEIIDFLRDPLG
NLQTLINDFMTNPSAALVTWGPLLSAVAYQVFTNLVGWPTWAMIFASPFLLAALIPLGIAGLVLIIDALKPELTQPPAEQ
TEPAPAPAPRPDQQVLPVAGVPAPGAPATPGTAPAGSSAAAPAAPAPAAAAAAPLVPYAVRGGDPGEGFTPTVRDSTGAK
APAGDIPAAAAAAAAASAAERRKRRRRKITEVKGRGYADVYMDYEDDPDEPPIVEPRVAASSRGAGAMGFTGTAPGAADA
RATGLTTLSPDAFGTGPVSPMLPGTWNPDSEPDQPAEGQEGGPRT

Specific function: Unknown

COG id: COG5651

COG function: function code N; PPE-repeat proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000030 [H]

Pfam domain/function: PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 52833; Mature: 52833

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPPIWMALPPEVHSALLSSGPGPGSLLAAAGAWQSLSAEYASAAAELTGILGSVQAGAW
CCCCCCEECCHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
EGPSAEQYVAAHTPYLAWLAQASANSAATAAQHETAAAAYTTALATMPTLGELAANHATH
CCCCCCCHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
AVLLATNFLGINTIPIAVNEADYVRMWIQAATSMSTYQAVAGAAVAAAPTTAPAPYLLAP
EEEEEHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECC
GVGEAGQAMASVQQLGAQAQASESGSALNISDSINQLLEQYLQSAPGGQEIIDFLRDPLG
CCCHHHHHHHHHHHHCCHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHH
NLQTLINDFMTNPSAALVTWGPLLSAVAYQVFTNLVGWPTWAMIFASPFLLAALIPLGIA
HHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GLVLIIDALKPELTQPPAEQTEPAPAPAPRPDQQVLPVAGVPAPGAPATPGTAPAGSSAA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APAAPAPAAAAAAPLVPYAVRGGDPGEGFTPTVRDSTGAKAPAGDIPAAAAAAAAASAAE
CCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RRKRRRRKITEVKGRGYADVYMDYEDDPDEPPIVEPRVAASSRGAGAMGFTGTAPGAADA
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
RATGLTTLSPDAFGTGPVSPMLPGTWNPDSEPDQPAEGQEGGPRT
HHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVPPIWMALPPEVHSALLSSGPGPGSLLAAAGAWQSLSAEYASAAAELTGILGSVQAGAW
CCCCCCEECCHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
EGPSAEQYVAAHTPYLAWLAQASANSAATAAQHETAAAAYTTALATMPTLGELAANHATH
CCCCCCCHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
AVLLATNFLGINTIPIAVNEADYVRMWIQAATSMSTYQAVAGAAVAAAPTTAPAPYLLAP
EEEEEHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECC
GVGEAGQAMASVQQLGAQAQASESGSALNISDSINQLLEQYLQSAPGGQEIIDFLRDPLG
CCCHHHHHHHHHHHHCCHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHH
NLQTLINDFMTNPSAALVTWGPLLSAVAYQVFTNLVGWPTWAMIFASPFLLAALIPLGIA
HHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GLVLIIDALKPELTQPPAEQTEPAPAPAPRPDQQVLPVAGVPAPGAPATPGTAPAGSSAA
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APAAPAPAAAAAAPLVPYAVRGGDPGEGFTPTVRDSTGAKAPAGDIPAAAAAAAAASAAE
CCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RRKRRRRKITEVKGRGYADVYMDYEDDPDEPPIVEPRVAASSRGAGAMGFTGTAPGAADA
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
RATGLTTLSPDAFGTGPVSPMLPGTWNPDSEPDQPAEGQEGGPRT
HHCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]