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The map label for this gene is kshA [H]

Identifier: 108797276

GI number: 108797276

Start: 333574

End: 334710

Strand: Direct

Name: kshA [H]

Synonym: Mmcs_0296

Alternate gene names: 108797276

Gene position: 333574-334710 (Clockwise)

Preceding gene: 108797275

Following gene: 108797277

Centisome position: 5.85

GC content: 64.73

Gene sequence:

>1137_bases
ATGACGTCCGACATCGACGAGGTTCGGCAGATCGAGGCCGACGCGGCACCGACCCGGTTCGCCCGCGGGTGGCACTGTTT
GGGGTTGACGCGTGATTTCGGCGACGGTAAACCGCACACCGTCAACGCCTTCGGCCAGAAGCTCGTCGTGTTCCGCAGCG
GCGACGGCAGGATCAACGTGCTCGACGGCTACTGCCGTCACATGGGCGGTGACCTGAGCCAGGGCGAGGTCAAGGGCAAC
GAGATCGCCTGCCCGTTCCACGATTGGCGCTGGGGCGGCGACGGCCGCTGCAAGCAGGTCCCGTACAGCAAGCGGGCGCC
GCGGCTGGCCCGCACCGCGACGTGGACCACGCTGGAACAGGACGGCATGCTGTTCGTCTGGAACGACCCGGAGCGCAAAC
CGCCGCCCGACGACGTGACGATCCCCCGGATCGAGGGCGCCACCAGCGACGAGTGGACCGACTGGCACTGGTACACCACG
GTGGTCGACACCAACTGCCGTGAGGTCATCGACAACGTCGTCGACATGGCGCACTTCTTCTACATCCACGGCTCGCTGCC
CACGCACTTCAAGAACATCTTCGAAGGCCACGTCGCCACCCAGTACATGAACAGCGCGGGACGCGCCGACCTCCAGCCCC
CGGAGGGACCGCGGATGCTGGGCACCACCTCCGTCGCCTCCTACCACGGGCCCTCGTTCATGATCGACGACCTGACGTAC
CACTACGAAGAGGCCGATCACCACACCGTGCTGATCAACTGCCACTATCCGATCGACGCGAATTCCTTTGTGCTGCAATA
CGGCATCATCGTCAAGAAATCCGAGGCGCTGCCCGACGACCTGGCGGTGCAGACCGCCGTCTCGCTGGGCGACTTCGTCA
AGATGGGTTTCGAACAGGACGTCGAGATCTGGAAGAACAAGGCCCGCATCGACAATCCCCTCCTGTGCGAGGAGGACGGG
CCGGTGTATCAATTGCGGCGCTGGTACGAGCAGTTCTACGTCGACATCGCCGACGTCACCCCCGATATGGTCGACCGATT
CGAGTACGAGGTCGACACCACCCGCCCGCGGGAGGAGTGGATGAAGATCGTCGAGGCCAACATCAGCGCACGGGCGTCGG
CGACGAGCGCGGGATGA

Upstream 100 bases:

>100_bases
CCGACTGTTGACGGCCGGTGTCGCGGGGCAGCGGTCCGACCTGTCCTGATGAGCGGAACATTCGCCCCCTGGCGCCACCG
CCCGGCGGTAGAACTGTCAC

Downstream 100 bases:

>100_bases
GCGTCCGGCCCGACAACCGGCTCGACGACGCCCCCATGGTGCCGGTCGCGTGCCGGGCCTGCGGCGCGAAAGTGCTCGCC
CGCAAGAGCAGTTGGCAACA

Product: Rieske (2Fe-2S) domain-containing protein

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTSDIDEVRQIEADAAPTRFARGWHCLGLTRDFGDGKPHTVNAFGQKLVVFRSGDGRINVLDGYCRHMGGDLSQGEVKGN
EIACPFHDWRWGGDGRCKQVPYSKRAPRLARTATWTTLEQDGMLFVWNDPERKPPPDDVTIPRIEGATSDEWTDWHWYTT
VVDTNCREVIDNVVDMAHFFYIHGSLPTHFKNIFEGHVATQYMNSAGRADLQPPEGPRMLGTTSVASYHGPSFMIDDLTY
HYEEADHHTVLINCHYPIDANSFVLQYGIIVKKSEALPDDLAVQTAVSLGDFVKMGFEQDVEIWKNKARIDNPLLCEEDG
PVYQLRRWYEQFYVDIADVTPDMVDRFEYEVDTTRPREEWMKIVEANISARASATSAG

Sequences:

>Translated_378_residues
MTSDIDEVRQIEADAAPTRFARGWHCLGLTRDFGDGKPHTVNAFGQKLVVFRSGDGRINVLDGYCRHMGGDLSQGEVKGN
EIACPFHDWRWGGDGRCKQVPYSKRAPRLARTATWTTLEQDGMLFVWNDPERKPPPDDVTIPRIEGATSDEWTDWHWYTT
VVDTNCREVIDNVVDMAHFFYIHGSLPTHFKNIFEGHVATQYMNSAGRADLQPPEGPRMLGTTSVASYHGPSFMIDDLTY
HYEEADHHTVLINCHYPIDANSFVLQYGIIVKKSEALPDDLAVQTAVSLGDFVKMGFEQDVEIWKNKARIDNPLLCEEDG
PVYQLRRWYEQFYVDIADVTPDMVDRFEYEVDTTRPREEWMKIVEANISARASATSAG
>Mature_377_residues
TSDIDEVRQIEADAAPTRFARGWHCLGLTRDFGDGKPHTVNAFGQKLVVFRSGDGRINVLDGYCRHMGGDLSQGEVKGNE
IACPFHDWRWGGDGRCKQVPYSKRAPRLARTATWTTLEQDGMLFVWNDPERKPPPDDVTIPRIEGATSDEWTDWHWYTTV
VDTNCREVIDNVVDMAHFFYIHGSLPTHFKNIFEGHVATQYMNSAGRADLQPPEGPRMLGTTSVASYHGPSFMIDDLTYH
YEEADHHTVLINCHYPIDANSFVLQYGIIVKKSEALPDDLAVQTAVSLGDFVKMGFEQDVEIWKNKARIDNPLLCEEDGP
VYQLRRWYEQFYVDIADVTPDMVDRFEYEVDTTRPREEWMKIVEANISARASATSAG

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71983709, Length=341, Percent_Identity=28.4457478005865, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI161085896, Length=353, Percent_Identity=25.4957507082153, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017941 [H]

Pfam domain/function: PF00355 Rieske [H]

EC number: 1.14.1.- [C]

Molecular weight: Translated: 42987; Mature: 42856

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDIDEVRQIEADAAPTRFARGWHCLGLTRDFGDGKPHTVNAFGQKLVVFRSGDGRINV
CCCCHHHHHHHHCCCCCHHHHCCEEEEEEECCCCCCCCEEEECCCCEEEEEECCCCEEEE
LDGYCRHMGGDLSQGEVKGNEIACPFHDWRWGGDGRCKQVPYSKRAPRLARTATWTTLEQ
ECHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEEEECC
DGMLFVWNDPERKPPPDDVTIPRIEGATSDEWTDWHWYTTVVDTNCREVIDNVVDMAHFF
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHEE
YIHGSLPTHFKNIFEGHVATQYMNSAGRADLQPPEGPRMLGTTSVASYHGPSFMIDDLTY
EEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHCCCCCCEEECCCEE
HYEEADHHTVLINCHYPIDANSFVLQYGIIVKKSEALPDDLAVQTAVSLGDFVKMGFEQD
EEECCCCCEEEEEEECCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHH
VEIWKNKARIDNPLLCEEDGPVYQLRRWYEQFYVDIADVTPDMVDRFEYEVDTTRPREEW
HHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCCHHHH
MKIVEANISARASATSAG
HHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TSDIDEVRQIEADAAPTRFARGWHCLGLTRDFGDGKPHTVNAFGQKLVVFRSGDGRINV
CCCHHHHHHHHCCCCCHHHHCCEEEEEEECCCCCCCCEEEECCCCEEEEEECCCCEEEE
LDGYCRHMGGDLSQGEVKGNEIACPFHDWRWGGDGRCKQVPYSKRAPRLARTATWTTLEQ
ECHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEEEEECC
DGMLFVWNDPERKPPPDDVTIPRIEGATSDEWTDWHWYTTVVDTNCREVIDNVVDMAHFF
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHEE
YIHGSLPTHFKNIFEGHVATQYMNSAGRADLQPPEGPRMLGTTSVASYHGPSFMIDDLTY
EEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHCCCCCCEEECCCEE
HYEEADHHTVLINCHYPIDANSFVLQYGIIVKKSEALPDDLAVQTAVSLGDFVKMGFEQD
EEECCCCCEEEEEEECCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHH
VEIWKNKARIDNPLLCEEDGPVYQLRRWYEQFYVDIADVTPDMVDRFEYEVDTTRPREEW
HHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCCCHHHH
MKIVEANISARASATSAG
HHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA