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The map label for this gene is mdmB [H]

Identifier: 108797202

GI number: 108797202

Start: 243802

End: 244980

Strand: Direct

Name: mdmB [H]

Synonym: Mmcs_0222

Alternate gene names: 108797202

Gene position: 243802-244980 (Clockwise)

Preceding gene: 108797199

Following gene: 108797205

Centisome position: 4.27

GC content: 71.5

Gene sequence:

>1179_bases
GTGACGAGCAGCGAGGAGATCGGCGGGACGCGGTCGTTCCTGCCCGCCGTCGAGGGCATGCGCGCCTGCGCGGCCATCGG
CGTCGTCGTCACCCACGTCGCCTTCCAGACCGGGCACACCAGCGGGGCGGACGGCCGGTTCTTCGGACGGTTCGATCTGG
CGGTCGCGGTGTTCTTCGCGCTCTCGGGGTTCCTGCTGTGGCGCGGGCACGCCGCCGCGGCGCGGGGACTGCGAACCGCC
CCGCCGACCGCCCACTACCTCCGCTCACGCATCGTCCGCATCATGCCGGGTTATCTGGTCGCGGTCGTGATCATCCTGTC
GCTGTTCCCGGACACCAAACCGGACCTCACGGTGTGGCTGGCCAACCTGAGCCTCACCCAGATCTACGTCCCGCTCACCC
TGACCGCGGGGCTGACCCAGATGTGGAGCCTGTCGGTCGAGGTCAGTTTCTATCTCGTGTTGCCGCTGCTGGCGCTGTCG
GTGCGACGGGTGCCGGTCCGGGCGCGGATCCCGGTCATCGTCGGCGCCGCGGTGGCGAGCCTGTTCTGGGTCTACATCCC
GTCGGACCCCGACTCCGGGCACAACCTCTGGAACTGGCCGCCGGCCTTCTTCTCCTGGTTCGCCGCGGGCATGGTGCTGG
CGGAACTGACCGTCACGCAGGTCGGGTGGGCCCACCGGCTGGCGCGCCGACGCATCCTGATGGCGGCGATCGTGGTGGCG
GCCTTCGCGGTCGCCGCCTCACCGCTGGCCGGCCGTGAGGGCCTGCAACCCGGCACCATCGGCCAGGTCATCCTCAAGAC
GGCGATGGGCGCGGTGGTGGCCGGGGCGCTGCTGGCGCCGCTGGTGCTCGACCGGCCGGACACCCCGCACCGGATCCTGG
GCAGCCGGGTGATGGTGACGCTGGGGCGCTGGTCCTACGGGCTGTTCATCTGGCACCTCGCGGCGCTGGCGATGGTCTTC
CCGATGGTGGGGGAGTTCGCGTTCAACGGGCACATGCCGTCGGTGCTGGCGCTGACCCTGCTGTTCGGCTTCGCGCTCGC
CGCGGTGAGCTACGCGTGCGTGGAGAGCCCGGCCCGGGAGGCGCTGCGCCGCTGGGAGTTCCGACGGGCCACGCCGACGC
ACAGGGCGCCGCCGCTGGACAGTTCGGTCACGGACGTGCCCGAGCCGATCTCGCGATGA

Upstream 100 bases:

>100_bases
AAAACCCGTTTGACCCTAACAGCAGACATTAAGGCGGGAACTTACTACGAGACCTCCACCGCGCCCGGCTCAGCCCTGTC
ACGCTGGCACACTGGTCGCC

Downstream 100 bases:

>100_bases
CCTCGGCGCGGACGGCGGAGCGACGGGCCTTACCCGCGTCGTCGCGCAGCGGATGTTCGCTGAACTCGACGGTGCGCGGC
ACCTTGTAGCCGGCCAGGCG

Product: acyltransferase 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTSSEEIGGTRSFLPAVEGMRACAAIGVVVTHVAFQTGHTSGADGRFFGRFDLAVAVFFALSGFLLWRGHAAAARGLRTA
PPTAHYLRSRIVRIMPGYLVAVVIILSLFPDTKPDLTVWLANLSLTQIYVPLTLTAGLTQMWSLSVEVSFYLVLPLLALS
VRRVPVRARIPVIVGAAVASLFWVYIPSDPDSGHNLWNWPPAFFSWFAAGMVLAELTVTQVGWAHRLARRRILMAAIVVA
AFAVAASPLAGREGLQPGTIGQVILKTAMGAVVAGALLAPLVLDRPDTPHRILGSRVMVTLGRWSYGLFIWHLAALAMVF
PMVGEFAFNGHMPSVLALTLLFGFALAAVSYACVESPAREALRRWEFRRATPTHRAPPLDSSVTDVPEPISR

Sequences:

>Translated_392_residues
MTSSEEIGGTRSFLPAVEGMRACAAIGVVVTHVAFQTGHTSGADGRFFGRFDLAVAVFFALSGFLLWRGHAAAARGLRTA
PPTAHYLRSRIVRIMPGYLVAVVIILSLFPDTKPDLTVWLANLSLTQIYVPLTLTAGLTQMWSLSVEVSFYLVLPLLALS
VRRVPVRARIPVIVGAAVASLFWVYIPSDPDSGHNLWNWPPAFFSWFAAGMVLAELTVTQVGWAHRLARRRILMAAIVVA
AFAVAASPLAGREGLQPGTIGQVILKTAMGAVVAGALLAPLVLDRPDTPHRILGSRVMVTLGRWSYGLFIWHLAALAMVF
PMVGEFAFNGHMPSVLALTLLFGFALAAVSYACVESPAREALRRWEFRRATPTHRAPPLDSSVTDVPEPISR
>Mature_391_residues
TSSEEIGGTRSFLPAVEGMRACAAIGVVVTHVAFQTGHTSGADGRFFGRFDLAVAVFFALSGFLLWRGHAAAARGLRTAP
PTAHYLRSRIVRIMPGYLVAVVIILSLFPDTKPDLTVWLANLSLTQIYVPLTLTAGLTQMWSLSVEVSFYLVLPLLALSV
RRVPVRARIPVIVGAAVASLFWVYIPSDPDSGHNLWNWPPAFFSWFAAGMVLAELTVTQVGWAHRLARRRILMAAIVVAA
FAVAASPLAGREGLQPGTIGQVILKTAMGAVVAGALLAPLVLDRPDTPHRILGSRVMVTLGRWSYGLFIWHLAALAMVFP
MVGEFAFNGHMPSVLALTLLFGFALAAVSYACVESPAREALRRWEFRRATPTHRAPPLDSSVTDVPEPISR

Specific function: Catalyzes the acylation of the mycaminose sugar during midecamycin biosynthesis [H]

COG id: COG1835

COG function: function code I; Predicted acyltransferases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002656 [H]

Pfam domain/function: PF01757 Acyl_transf_3 [H]

EC number: NA

Molecular weight: Translated: 42413; Mature: 42282

Theoretical pI: Translated: 10.93; Mature: 10.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSEEIGGTRSFLPAVEGMRACAAIGVVVTHVAFQTGHTSGADGRFFGRFDLAVAVFFA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHH
LSGFLLWRGHAAAARGLRTAPPTAHYLRSRIVRIMPGYLVAVVIILSLFPDTKPDLTVWL
HHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
ANLSLTQIYVPLTLTAGLTQMWSLSVEVSFYLVLPLLALSVRRVPVRARIPVIVGAAVAS
ECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LFWVYIPSDPDSGHNLWNWPPAFFSWFAAGMVLAELTVTQVGWAHRLARRRILMAAIVVA
HEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFAVAASPLAGREGLQPGTIGQVILKTAMGAVVAGALLAPLVLDRPDTPHRILGSRVMVT
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHEEE
LGRWSYGLFIWHLAALAMVFPMVGEFAFNGHMPSVLALTLLFGFALAAVSYACVESPARE
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ALRRWEFRRATPTHRAPPLDSSVTDVPEPISR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TSSEEIGGTRSFLPAVEGMRACAAIGVVVTHVAFQTGHTSGADGRFFGRFDLAVAVFFA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHH
LSGFLLWRGHAAAARGLRTAPPTAHYLRSRIVRIMPGYLVAVVIILSLFPDTKPDLTVWL
HHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
ANLSLTQIYVPLTLTAGLTQMWSLSVEVSFYLVLPLLALSVRRVPVRARIPVIVGAAVAS
ECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
LFWVYIPSDPDSGHNLWNWPPAFFSWFAAGMVLAELTVTQVGWAHRLARRRILMAAIVVA
HEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFAVAASPLAGREGLQPGTIGQVILKTAMGAVVAGALLAPLVLDRPDTPHRILGSRVMVT
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHEEE
LGRWSYGLFIWHLAALAMVFPMVGEFAFNGHMPSVLALTLLFGFALAAVSYACVESPARE
ECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ALRRWEFRRATPTHRAPPLDSSVTDVPEPISR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]