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The map label for this gene is atsA [H]

Identifier: 108763309

GI number: 108763309

Start: 3984598

End: 3986979

Strand: Direct

Name: atsA [H]

Synonym: MXAN_3428

Alternate gene names: 108763309

Gene position: 3984598-3986979 (Clockwise)

Preceding gene: 108761493

Following gene: 108760181

Centisome position: 43.6

GC content: 65.99

Gene sequence:

>2382_bases
ATGAAGACGTACCACGAAGGGGAGCGTTTCCCCGGCCGCATTGGCAGGACGTGGGAGGAGTCCGAGCCGGCCTTCCCCGT
GCCTCCCGAGGCGCCGAAGGGGGCGCCGAACATCCTGTACATCATCCTCGACGACGTCGGTTACGGGGCGTGTGACACGT
TCGGCGGCCTGGTCGAGACGCCGAACATCACGCGGCTCGCCGGCAACGGTCTCCGGTACACCAACTTCCACACGACGGCC
CTCTGCTCACCGACGCGCGCGTGCCTCTTGACGGGGCGCAACCACCACTCGGTTGGCATGGCCAACATCACCGAGCTCGC
AACCGGCTTCCCTGGCTACGACGCGCGCCAGAAGCCGGACAAGGCCGCCATTGGCGCGATGCTCCACCAGCACGGCTACG
CGTCGTTCGCGCTCGGCAAGTGGCACAACACGCCGTCGGAGGAGTCCGGCCCCTCGGGCCCGTTCGACCGGTGGCCCGAC
GGGCCGCTCTTCGGGTTCGACCGCTTCTACGGCTTCATGGGCGGTGACAACAACCAGTGGTACCCGAAGCTCTACGCGGG
GCGCGAGGCCATCGACCCTCCGCGCCTGCCGCAGGAGGGCTACCACCTGTCGGAGGACCTCGCCGACAAGACGGTCGATT
TCATCTCGAACCATGCGTCGTTGACGCCCGAGAAGCCGTGGCTCGCCTACCTCGCGTTCGGCGCCTGCCACGCTCCGCAC
CACGTCTGGCCAGAGTGGATTGAGAAGTACCGTGGCAAGTTCGACATGGGGTGGGACCGCTACCGCGAGCAGGTGCTGGC
GCGGCAGAAGCAGTTGGGCGTCATTCCGGCCAACGCCGCACTCGCGCCCATGCTCGAAGGCGTGCCCAGGTGGGATGATT
TGTCGGACGACCAGAAGCGGCTCTTCGCGCGGATGGCCGAGGTCTACGCCGCCTTCCTGTCGCACGCGGACGCGCAGATT
GGGCGCGTCGTCGAGTACTTGGAGCGGTCGGGCCAGCTCGACAACACGTTGCTCTTCGTGTTCATCGGCGACAACGGCTG
CTCCGGCGAAGGCACGAACTCGGGCCTCTTCAACGAGGGCGCGCTCGGCACGGAGCGCCCCGAGACGGTCGAGACTCTGG
AGGGGAACCTCCAGCGCATCGACAGGCTCGGGCAGCCGGGCTCCTATAACCACTTCCCGGTGGGGTGGGCACTGGCGATG
AATGCACCGTTCAAGCTCTGCAAGCAGTACACGCACTTCGGCGGGACGCGGAATCCCCTCGTGGTGCACTGGCCCAAGGG
CATCCAGGCCCGAGGTGAAATCAGGACGCAGTTCCACCACGTCATCGACATCGTCCCCACCATCCTGAAGGCCGCCAGGA
TTGAGGCGCCCGCCGTCGTCAACTCCGTCTCCCAGGCGCCGATGGAAGGCGTGCCGATGAATTACTCGTTCGACGACGCG
GACGCGCCCACTCATCACCCGACGCAATACTTCGAGATGCTGGGCAACCGCGCCATCGTCAACGGGAAGTGGAAGGCCGT
CACCTACCACGGTCGCAAGCCGTGGGAGAACCATGCGGCCTGGTCCTTCGACGAGGATCACTGGGAGGTCTACGACCTCG
AGAAAGACCCGACCGAGTGTCATGACCTCATGGCGCAGCGGGATTTGTCGAAGCAAGATGACCCGGCCGTGAAGCGGATG
ATTCATCTGGTCGGCCTGTGGTGGGCCGAGGCCGGCCGCTACAACGTGCTCCCGCTCGATGACCGGTTCCAGGAGCGCCT
GCTGGGGAGGGCCGAGCTGGCCAAGAAACGGACGCGGTTCACGTTCGGGCTGGGGGCGGTACGGATTCCCGAGGCCGCGG
CGCCCGACACGAAAAACCGCTCGTGGGCCATGACCGCCGAGATTGAAATCCCCGAGCAGGGCGCCGAAGGTCCCATCGTC
GTGATGGGCGGAGACACCGCCGGGTGGTCCCTCTACCTGAAAGGCGGCGTCCCCACGTTTTGCTACAACTTCGCCGCTGT
CGAATACACATACATCCGTGCGCAGCAGAAGATCGGTCCGGGCCGCCACACGCTCCGCTTCGAGTTCGAAATCCAGCCCG
AGCATCGAACCGACACGGGCAAGCCCGTCATTTACGGCGCCGGAGGCATGGGCCGCCTCGCGGTGGACGGCAAGTGGGTC
GCCGAGGGCAGGATTCCGCAGACGATGGCGTTCATGTACAGCCTCGACGAGACGTTCGACGTCGGCTGCGACAAGGGAGC
GCCCGTGACCGACGAGTATGAGCCGCTCGCGGCCTTTACGGGCAAGGTCGTCGAAGTCACCGTGGACTTGCACCCGGAGA
CAGCGTTGGAGCCAGCACGCCACACGGATGCTCAGGTCACCCAGGCGATGGCCCGGCAGTGA

Upstream 100 bases:

>100_bases
GGAGAGGGGGAGGCCCGACATGGCGCGGAAGAGTGGCAAGGGGAAGACGTCCGAGGAGCAGCAGGGCGGCGACGGGCAGT
CGGCGGCGGTCTCCGGTGGA

Downstream 100 bases:

>100_bases
GGGAGGGCTTCTCACCCTGGAGGCAGGACGCGAAATCGCGGACATCGCTACGTGACAGCAACTGTCGTCGCGCGGTCATG
TGGCTCGCTACGTAATCGCA

Product: sulfatase family protein

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 793; Mature: 793

Protein sequence:

>793_residues
MKTYHEGERFPGRIGRTWEESEPAFPVPPEAPKGAPNILYIILDDVGYGACDTFGGLVETPNITRLAGNGLRYTNFHTTA
LCSPTRACLLTGRNHHSVGMANITELATGFPGYDARQKPDKAAIGAMLHQHGYASFALGKWHNTPSEESGPSGPFDRWPD
GPLFGFDRFYGFMGGDNNQWYPKLYAGREAIDPPRLPQEGYHLSEDLADKTVDFISNHASLTPEKPWLAYLAFGACHAPH
HVWPEWIEKYRGKFDMGWDRYREQVLARQKQLGVIPANAALAPMLEGVPRWDDLSDDQKRLFARMAEVYAAFLSHADAQI
GRVVEYLERSGQLDNTLLFVFIGDNGCSGEGTNSGLFNEGALGTERPETVETLEGNLQRIDRLGQPGSYNHFPVGWALAM
NAPFKLCKQYTHFGGTRNPLVVHWPKGIQARGEIRTQFHHVIDIVPTILKAARIEAPAVVNSVSQAPMEGVPMNYSFDDA
DAPTHHPTQYFEMLGNRAIVNGKWKAVTYHGRKPWENHAAWSFDEDHWEVYDLEKDPTECHDLMAQRDLSKQDDPAVKRM
IHLVGLWWAEAGRYNVLPLDDRFQERLLGRAELAKKRTRFTFGLGAVRIPEAAAPDTKNRSWAMTAEIEIPEQGAEGPIV
VMGGDTAGWSLYLKGGVPTFCYNFAAVEYTYIRAQQKIGPGRHTLRFEFEIQPEHRTDTGKPVIYGAGGMGRLAVDGKWV
AEGRIPQTMAFMYSLDETFDVGCDKGAPVTDEYEPLAAFTGKVVEVTVDLHPETALEPARHTDAQVTQAMARQ

Sequences:

>Translated_793_residues
MKTYHEGERFPGRIGRTWEESEPAFPVPPEAPKGAPNILYIILDDVGYGACDTFGGLVETPNITRLAGNGLRYTNFHTTA
LCSPTRACLLTGRNHHSVGMANITELATGFPGYDARQKPDKAAIGAMLHQHGYASFALGKWHNTPSEESGPSGPFDRWPD
GPLFGFDRFYGFMGGDNNQWYPKLYAGREAIDPPRLPQEGYHLSEDLADKTVDFISNHASLTPEKPWLAYLAFGACHAPH
HVWPEWIEKYRGKFDMGWDRYREQVLARQKQLGVIPANAALAPMLEGVPRWDDLSDDQKRLFARMAEVYAAFLSHADAQI
GRVVEYLERSGQLDNTLLFVFIGDNGCSGEGTNSGLFNEGALGTERPETVETLEGNLQRIDRLGQPGSYNHFPVGWALAM
NAPFKLCKQYTHFGGTRNPLVVHWPKGIQARGEIRTQFHHVIDIVPTILKAARIEAPAVVNSVSQAPMEGVPMNYSFDDA
DAPTHHPTQYFEMLGNRAIVNGKWKAVTYHGRKPWENHAAWSFDEDHWEVYDLEKDPTECHDLMAQRDLSKQDDPAVKRM
IHLVGLWWAEAGRYNVLPLDDRFQERLLGRAELAKKRTRFTFGLGAVRIPEAAAPDTKNRSWAMTAEIEIPEQGAEGPIV
VMGGDTAGWSLYLKGGVPTFCYNFAAVEYTYIRAQQKIGPGRHTLRFEFEIQPEHRTDTGKPVIYGAGGMGRLAVDGKWV
AEGRIPQTMAFMYSLDETFDVGCDKGAPVTDEYEPLAAFTGKVVEVTVDLHPETALEPARHTDAQVTQAMARQ
>Mature_793_residues
MKTYHEGERFPGRIGRTWEESEPAFPVPPEAPKGAPNILYIILDDVGYGACDTFGGLVETPNITRLAGNGLRYTNFHTTA
LCSPTRACLLTGRNHHSVGMANITELATGFPGYDARQKPDKAAIGAMLHQHGYASFALGKWHNTPSEESGPSGPFDRWPD
GPLFGFDRFYGFMGGDNNQWYPKLYAGREAIDPPRLPQEGYHLSEDLADKTVDFISNHASLTPEKPWLAYLAFGACHAPH
HVWPEWIEKYRGKFDMGWDRYREQVLARQKQLGVIPANAALAPMLEGVPRWDDLSDDQKRLFARMAEVYAAFLSHADAQI
GRVVEYLERSGQLDNTLLFVFIGDNGCSGEGTNSGLFNEGALGTERPETVETLEGNLQRIDRLGQPGSYNHFPVGWALAM
NAPFKLCKQYTHFGGTRNPLVVHWPKGIQARGEIRTQFHHVIDIVPTILKAARIEAPAVVNSVSQAPMEGVPMNYSFDDA
DAPTHHPTQYFEMLGNRAIVNGKWKAVTYHGRKPWENHAAWSFDEDHWEVYDLEKDPTECHDLMAQRDLSKQDDPAVKRM
IHLVGLWWAEAGRYNVLPLDDRFQERLLGRAELAKKRTRFTFGLGAVRIPEAAAPDTKNRSWAMTAEIEIPEQGAEGPIV
VMGGDTAGWSLYLKGGVPTFCYNFAAVEYTYIRAQQKIGPGRHTLRFEFEIQPEHRTDTGKPVIYGAGGMGRLAVDGKWV
AEGRIPQTMAFMYSLDETFDVGCDKGAPVTDEYEPLAAFTGKVVEVTVDLHPETALEPARHTDAQVTQAMARQ

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI38569405, Length=554, Percent_Identity=23.826714801444, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI38569407, Length=335, Percent_Identity=23.8805970149254, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI146229331, Length=528, Percent_Identity=23.6742424242424, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI146229329, Length=528, Percent_Identity=23.6742424242424, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI6005990, Length=528, Percent_Identity=23.6742424242424, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI146229324, Length=528, Percent_Identity=23.6742424242424, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI59797060, Length=269, Percent_Identity=25.6505576208178, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI4503899, Length=225, Percent_Identity=31.1111111111111, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI71852586, Length=158, Percent_Identity=35.4430379746835, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI71852584, Length=151, Percent_Identity=35.7615894039735, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI157266309, Length=154, Percent_Identity=33.7662337662338, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI109389362, Length=250, Percent_Identity=24.4, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI31742482, Length=150, Percent_Identity=34, Blast_Score=71, Evalue=5e-12,
Organism=Escherichia coli, GI87081924, Length=472, Percent_Identity=22.6694915254237, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790233, Length=502, Percent_Identity=22.7091633466135, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115533416, Length=571, Percent_Identity=22.5919439579685, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559078, Length=232, Percent_Identity=26.2931034482759, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281363223, Length=494, Percent_Identity=22.8744939271255, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281366397, Length=336, Percent_Identity=25.5952380952381, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281366395, Length=336, Percent_Identity=25.5952380952381, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24666163, Length=336, Percent_Identity=25.5952380952381, Blast_Score=86, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 88497; Mature: 88497

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00334 MYB_2 ; PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYHEGERFPGRIGRTWEESEPAFPVPPEAPKGAPNILYIILDDVGYGACDTFGGLVET
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHCCCCCCC
PNITRLAGNGLRYTNFHTTALCSPTRACLLTGRNHHSVGMANITELATGFPGYDARQKPD
CCEEEECCCCEEEECCCCCEECCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCC
KAAIGAMLHQHGYASFALGKWHNTPSEESGPSGPFDRWPDGPLFGFDRFYGFMGGDNNQW
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCC
YPKLYAGREAIDPPRLPQEGYHLSEDLADKTVDFISNHASLTPEKPWLAYLAFGACHAPH
CCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCC
HVWPEWIEKYRGKFDMGWDRYREQVLARQKQLGVIPANAALAPMLEGVPRWDDLSDDQKR
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHH
LFARMAEVYAAFLSHADAQIGRVVEYLERSGQLDNTLLFVFIGDNGCSGEGTNSGLFNEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
ALGTERPETVETLEGNLQRIDRLGQPGSYNHFPVGWALAMNAPFKLCKQYTHFGGTRNPL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCE
VVHWPKGIQARGEIRTQFHHVIDIVPTILKAARIEAPAVVNSVSQAPMEGVPMNYSFDDA
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCC
DAPTHHPTQYFEMLGNRAIVNGKWKAVTYHGRKPWENHAAWSFDEDHWEVYDLEKDPTEC
CCCCCCHHHHHHHHCCEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCHHHH
HDLMAQRDLSKQDDPAVKRMIHLVGLWWAEAGRYNVLPLDDRFQERLLGRAELAKKRTRF
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHE
TFGLGAVRIPEAAAPDTKNRSWAMTAEIEIPEQGAEGPIVVMGGDTAGWSLYLKGGVPTF
EECCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCCCEEEEEECCCCHH
CYNFAAVEYTYIRAQQKIGPGRHTLRFEFEIQPEHRTDTGKPVIYGAGGMGRLAVDGKWV
HHHHHHEEEEEEEHHHHCCCCCEEEEEEEEECCCCCCCCCCEEEEECCCCCEEEECCEEE
AEGRIPQTMAFMYSLDETFDVGCDKGAPVTDEYEPLAAFTGKVVEVTVDLHPETALEPAR
ECCCCCHHHHHHHHCCCHHCCCCCCCCCCCCCCCHHHHHCCCEEEEEEEECCCHHCCCCC
HTDAQVTQAMARQ
CCHHHHHHHHHCC
>Mature Secondary Structure
MKTYHEGERFPGRIGRTWEESEPAFPVPPEAPKGAPNILYIILDDVGYGACDTFGGLVET
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHCCCCCCC
PNITRLAGNGLRYTNFHTTALCSPTRACLLTGRNHHSVGMANITELATGFPGYDARQKPD
CCEEEECCCCEEEECCCCCEECCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCC
KAAIGAMLHQHGYASFALGKWHNTPSEESGPSGPFDRWPDGPLFGFDRFYGFMGGDNNQW
HHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCC
YPKLYAGREAIDPPRLPQEGYHLSEDLADKTVDFISNHASLTPEKPWLAYLAFGACHAPH
CCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCC
HVWPEWIEKYRGKFDMGWDRYREQVLARQKQLGVIPANAALAPMLEGVPRWDDLSDDQKR
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHH
LFARMAEVYAAFLSHADAQIGRVVEYLERSGQLDNTLLFVFIGDNGCSGEGTNSGLFNEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
ALGTERPETVETLEGNLQRIDRLGQPGSYNHFPVGWALAMNAPFKLCKQYTHFGGTRNPL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCE
VVHWPKGIQARGEIRTQFHHVIDIVPTILKAARIEAPAVVNSVSQAPMEGVPMNYSFDDA
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCC
DAPTHHPTQYFEMLGNRAIVNGKWKAVTYHGRKPWENHAAWSFDEDHWEVYDLEKDPTEC
CCCCCCHHHHHHHHCCEEEECCEEEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCHHHH
HDLMAQRDLSKQDDPAVKRMIHLVGLWWAEAGRYNVLPLDDRFQERLLGRAELAKKRTRF
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHE
TFGLGAVRIPEAAAPDTKNRSWAMTAEIEIPEQGAEGPIVVMGGDTAGWSLYLKGGVPTF
EECCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCCCEEEEEECCCCHH
CYNFAAVEYTYIRAQQKIGPGRHTLRFEFEIQPEHRTDTGKPVIYGAGGMGRLAVDGKWV
HHHHHHEEEEEEEHHHHCCCCCEEEEEEEEECCCCCCCCCCEEEEECCCCCEEEECCEEE
AEGRIPQTMAFMYSLDETFDVGCDKGAPVTDEYEPLAAFTGKVVEVTVDLHPETALEPAR
ECCCCCHHHHHHHHCCCHHCCCCCCCCCCCCCCCHHHHHCCCEEEEEEEECCCHHCCCCC
HTDAQVTQAMARQ
CCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]