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The map label for this gene is bcd [H]

Identifier: 108763116

GI number: 108763116

Start: 4563644

End: 4564786

Strand: Reverse

Name: bcd [H]

Synonym: MXAN_3797

Alternate gene names: 108763116

Gene position: 4564786-4563644 (Counterclockwise)

Preceding gene: 108759837

Following gene: 108759786

Centisome position: 49.94

GC content: 66.32

Gene sequence:

>1143_bases
ATGAACTTCGAGTTGACCGACATCCAGCGTGAAATCCAGCGGATGACCCGCGAGTTCGCGGCCAAGGAGCTCATCCCCAA
CGCCCGCAAGTGGGACGAGCACCACGCCTGGCCGACCGACGCGGTGAAGAAGCTGGCCGAGCTGTCCCTGCTGGGCGTGG
CCGTTCCCGAGCAGAACGGCGGCGCCGGGCTCGACAACGTCTGTTACGCCATCGCCATGGAGGAGATCAGCCGCGGCTGT
GCCTCCACCGGCGTCATCATGAGCGTGAACAACTCGCTCTACTGCGATCCGATCATGAAGTACGGCACGGATGCGCAGAA
GGAGCAGTTCCTGGCGCCCTTCGCCCGGGGCGAGAAGCTGGGCTGCTTCGGCCTCACCGAGCCCGAGGCCGGCAGCGACG
CCGCCGCGCAGAAGACGGTCGCCGTGCGCAAGGGTGACGAGTACGTCATCAACGGCTCGAAGAACTGGATCACCAACGGC
CCCAAGGCCGACGCCATCGTCCTGATGACGATGACCAACAAGGAAGCGGGCCACAAGGGCATCACCGCGTTCATGGTCCC
CACGGACACGCCGGGGTTCATCCGCGCCGAGCCGGACAAGAAGATGGGCATCAGCGCCGCCTGGTCCTGCTCCATGTTCT
TTGAGGACATGCGCGTGCCGGCCAAGTACATGCTCGGCAAGGAAGGCGAGGGCTTCAAGATCGCCATGAGCACGCTGGAC
GGCGGCCGCATCGGCATCGCGTCGCAGGCGCTGGGCATCGCGCGCGCGGCGTACGAGGAGGCGGTGCGCTACTCCGGTGA
GCGCAAGTCCTTCGGCAAGCCCATCCGCGAGCACCAGGCCATCCAGTTCATGATCGCCGACATGGCCACGGAGATCGACG
CGGCCCGGCTGCTCGTGTGGCGGGCGGCCCTGCAGAAGGACAAGGGCGTGCGCCACAGCGCGGAGAGCGCCATGGCCAAG
CTGTACGCCAGCGAGATGGCCAGCCGCGTGGCGAACAAGGCCCTGCAGGTGCACGGCGGCATGGGCTACAGCAAGGAGAT
GGACGTGGAGCGCCACGTGCGCGACGCGCGCATCACCGAAATCTACGAGGGGACGAGCGAAATCCAGCGCATCGTCATCG
CCGCCAACCTGCTGAGGGAGTAA

Upstream 100 bases:

>100_bases
GCGACCGGACGGTGTCTCACCGGCACGCCACGGCGCGCTTCCGCGCACGCGCCGCGTCTTCGCTGTTCCAGAGGGAAGCC
CCTCATATTATGGAGGTTCC

Downstream 100 bases:

>100_bases
CCGTCATGACTCGAGCGCTTCTCTCCGCAGTCGTCCTGGCCTCGGCGGTGGCGCTCGCGCAGGGCGCCGCCCCCGCGAAG
GCGCCCACCGGCGGCAAGTC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNFELTDIQREIQRMTREFAAKELIPNARKWDEHHAWPTDAVKKLAELSLLGVAVPEQNGGAGLDNVCYAIAMEEISRGC
ASTGVIMSVNNSLYCDPIMKYGTDAQKEQFLAPFARGEKLGCFGLTEPEAGSDAAAQKTVAVRKGDEYVINGSKNWITNG
PKADAIVLMTMTNKEAGHKGITAFMVPTDTPGFIRAEPDKKMGISAAWSCSMFFEDMRVPAKYMLGKEGEGFKIAMSTLD
GGRIGIASQALGIARAAYEEAVRYSGERKSFGKPIREHQAIQFMIADMATEIDAARLLVWRAALQKDKGVRHSAESAMAK
LYASEMASRVANKALQVHGGMGYSKEMDVERHVRDARITEIYEGTSEIQRIVIAANLLRE

Sequences:

>Translated_380_residues
MNFELTDIQREIQRMTREFAAKELIPNARKWDEHHAWPTDAVKKLAELSLLGVAVPEQNGGAGLDNVCYAIAMEEISRGC
ASTGVIMSVNNSLYCDPIMKYGTDAQKEQFLAPFARGEKLGCFGLTEPEAGSDAAAQKTVAVRKGDEYVINGSKNWITNG
PKADAIVLMTMTNKEAGHKGITAFMVPTDTPGFIRAEPDKKMGISAAWSCSMFFEDMRVPAKYMLGKEGEGFKIAMSTLD
GGRIGIASQALGIARAAYEEAVRYSGERKSFGKPIREHQAIQFMIADMATEIDAARLLVWRAALQKDKGVRHSAESAMAK
LYASEMASRVANKALQVHGGMGYSKEMDVERHVRDARITEIYEGTSEIQRIVIAANLLRE
>Mature_380_residues
MNFELTDIQREIQRMTREFAAKELIPNARKWDEHHAWPTDAVKKLAELSLLGVAVPEQNGGAGLDNVCYAIAMEEISRGC
ASTGVIMSVNNSLYCDPIMKYGTDAQKEQFLAPFARGEKLGCFGLTEPEAGSDAAAQKTVAVRKGDEYVINGSKNWITNG
PKADAIVLMTMTNKEAGHKGITAFMVPTDTPGFIRAEPDKKMGISAAWSCSMFFEDMRVPAKYMLGKEGEGFKIAMSTLD
GGRIGIASQALGIARAAYEEAVRYSGERKSFGKPIREHQAIQFMIADMATEIDAARLLVWRAALQKDKGVRHSAESAMAK
LYASEMASRVANKALQVHGGMGYSKEMDVERHVRDARITEIYEGTSEIQRIVIAANLLRE

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=54.2328042328042, Blast_Score=413, Evalue=1e-115,
Organism=Homo sapiens, GI187960098, Length=378, Percent_Identity=40.4761904761905, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=40.4761904761905, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI7656849, Length=377, Percent_Identity=38.7267904509284, Blast_Score=272, Evalue=4e-73,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=38.0697050938338, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=35.3887399463807, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI226958414, Length=334, Percent_Identity=37.125748502994, Blast_Score=238, Evalue=9e-63,
Organism=Homo sapiens, GI4557235, Length=385, Percent_Identity=35.3246753246753, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=35.3246753246753, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI21361497, Length=356, Percent_Identity=35.6741573033708, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI4501857, Length=371, Percent_Identity=34.2318059299191, Blast_Score=211, Evalue=7e-55,
Organism=Homo sapiens, GI48976061, Length=393, Percent_Identity=32.0610687022901, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI211971008, Length=393, Percent_Identity=32.0610687022901, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI4503943, Length=374, Percent_Identity=28.8770053475936, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI7669494, Length=363, Percent_Identity=28.9256198347107, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI38505218, Length=353, Percent_Identity=30.3116147308782, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI87081958, Length=383, Percent_Identity=30.5483028720627, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1786223, Length=387, Percent_Identity=28.9405684754522, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI87082384, Length=267, Percent_Identity=28.8389513108614, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87081702, Length=357, Percent_Identity=24.3697478991597, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=40.7310704960835, Blast_Score=294, Evalue=4e-80,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=40.5759162303665, Blast_Score=293, Evalue=1e-79,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=39.3700787401575, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=36.9272237196765, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17538396, Length=382, Percent_Identity=34.5549738219895, Blast_Score=250, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI17506239, Length=370, Percent_Identity=36.4864864864865, Blast_Score=250, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=37.4005305039788, Blast_Score=250, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71990804, Length=291, Percent_Identity=40.2061855670103, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI71985184, Length=381, Percent_Identity=35.1706036745407, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17505929, Length=373, Percent_Identity=34.3163538873995, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17551932, Length=369, Percent_Identity=32.7913279132791, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17534353, Length=374, Percent_Identity=29.6791443850267, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI71985192, Length=328, Percent_Identity=32.9268292682927, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI71982178, Length=268, Percent_Identity=30.9701492537313, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=35.0649350649351, Blast_Score=157, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17531909, Length=237, Percent_Identity=33.7552742616034, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17562446, Length=329, Percent_Identity=31.0030395136778, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=33.5227272727273, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=54.2553191489362, Blast_Score=427, Evalue=1e-120,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=48.936170212766, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24660351, Length=381, Percent_Identity=40.4199475065617, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24666513, Length=370, Percent_Identity=38.6486486486486, Blast_Score=275, Evalue=3e-74,
Organism=Drosophila melanogaster, GI21355753, Length=382, Percent_Identity=36.9109947643979, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI281363737, Length=338, Percent_Identity=36.094674556213, Blast_Score=214, Evalue=6e-56,
Organism=Drosophila melanogaster, GI19920834, Length=379, Percent_Identity=30.0791556728232, Blast_Score=153, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41713; Mature: 41713

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFELTDIQREIQRMTREFAAKELIPNARKWDEHHAWPTDAVKKLAELSLLGVAVPEQNG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCCCC
GAGLDNVCYAIAMEEISRGCASTGVIMSVNNSLYCDPIMKYGTDAQKEQFLAPFARGEKL
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECHHHHCCCCHHHHHHHHHHHCCCCE
GCFGLTEPEAGSDAAAQKTVAVRKGDEYVINGSKNWITNGPKADAIVLMTMTNKEAGHKG
EEECCCCCCCCCCHHHHHEEEEECCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCC
ITAFMVPTDTPGFIRAEPDKKMGISAAWSCSMFFEDMRVPAKYMLGKEGEGFKIAMSTLD
CEEEEECCCCCCCEEECCCHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEEECC
GGRIGIASQALGIARAAYEEAVRYSGERKSFGKPIREHQAIQFMIADMATEIDAARLLVW
CCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RAALQKDKGVRHSAESAMAKLYASEMASRVANKALQVHGGMGYSKEMDVERHVRDARITE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
IYEGTSEIQRIVIAANLLRE
HHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFELTDIQREIQRMTREFAAKELIPNARKWDEHHAWPTDAVKKLAELSLLGVAVPEQNG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCCCC
GAGLDNVCYAIAMEEISRGCASTGVIMSVNNSLYCDPIMKYGTDAQKEQFLAPFARGEKL
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECHHHHCCCCHHHHHHHHHHHCCCCE
GCFGLTEPEAGSDAAAQKTVAVRKGDEYVINGSKNWITNGPKADAIVLMTMTNKEAGHKG
EEECCCCCCCCCCHHHHHEEEEECCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCCCCC
ITAFMVPTDTPGFIRAEPDKKMGISAAWSCSMFFEDMRVPAKYMLGKEGEGFKIAMSTLD
CEEEEECCCCCCCEEECCCHHCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEEECC
GGRIGIASQALGIARAAYEEAVRYSGERKSFGKPIREHQAIQFMIADMATEIDAARLLVW
CCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RAALQKDKGVRHSAESAMAKLYASEMASRVANKALQVHGGMGYSKEMDVERHVRDARITE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
IYEGTSEIQRIVIAANLLRE
HHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]