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The map label for this gene is gluP [H]

Identifier: 108762819

GI number: 108762819

Start: 6943918

End: 6945444

Strand: Reverse

Name: gluP [H]

Synonym: MXAN_5590

Alternate gene names: 108762819

Gene position: 6945444-6943918 (Counterclockwise)

Preceding gene: 108763786

Following gene: 108757551

Centisome position: 75.99

GC content: 73.94

Gene sequence:

>1527_bases
ATGCGACTTGGGGGGGCGCCCTGGCTCACGTTGATCCTCGCCACCGTGCTGGTGGGTATCCACGGCGCGGCGCGAGCCGC
GGGGCCGGTGGGGCTGGACACCCTGCTGCGGTGGGGCGCGAAGGCGGGGCCTCTGGTGGTGGACGCGGGCCAGGTCTGGC
GGCTCGTCACCGCCCACTTCCTGCACCGGGACTTCCCCCACCTGGCGCTCAATGTCCTGGTGCTGTTGGCGGCGGGAAGC
GGCCTGGAGCGCCTGTGCCGACGCCGGGACTACGCAGCGCTGCTGGTGGCGGCGGGGCTGGCCACCATGGCGGGCTCGCT
CGGCAGCTCCGGGGGCGTGAGCGTGGGGGCTTCTGGGCTCGTGTATGCCTGTGTGGGTGCGCTGCTTGTCCTGGGCCGGC
GTCACCGGGCGAAGCTGCCGGCGCGGTGGATGTCCAGCGAGGCCGCGGTGCCCACGGTGCTCGTCTTCCTATGGATGGGG
TGGACGTCGGTAGGCGTGGACAACGCGGGGCACCTGGGCGGTTTGCTCGCGGGGCTGCTGGCCGGCGTCTTCCTGGAGCC
GCGCTGGCACCCGGACACGGGCTGGCTGCGCCCGGTGGGGATGGTGGTGGCGGCGGTGGTGGTGACGGGGGGCGTGGTTG
CGGAGCGCTCCGTCTGGCGCATGGAGCGGGATGACGGCTTTGGCCTCTCCGTGGCCCTGCCGCGCGACTGGCGGGGCGAC
GTGGACGGGCAGGGCCGGCGGGCCTTCTCCAACGGACTGCCGGGGCGTGGCCGCGCGACCTTCTCGGCGGAGGCCATCGA
GGCGGGGGAGCCAGGAGACGGCTCGGTCCAGGCGCGGCAGTTCCAGCAGGAGGTGCTGGTTCAGGGCGCTCCGAGCCCCG
AGGGGCGGACGCTGAAGGTGACGGAGCCGGTGGCGGCGCGCGTGGGCGGGCGGAGCGCGCAGCGGCTGCATGCGGAGTTG
GAGGGGCCAGGGGGGCCCACTCACCTGATGGCGCTCTTCGTGCCACGGGGGGAGTGGGTGTACCGGCTGGTGTTCACCTG
GCCCGCGGCGTACCCCGCCTATCGCGAGGTGGTGGACCGGATGGTGGCGGAGGTCCGCTTCGACGAGCCGTCCGTCCTAC
GCGAGGCGCGGGCTAGAGCGCTGCTCGTTCCGGGGGCGCCGGGACCGTTGCGCGCATTGGGCGGAGTGCTGCGCCGCCTG
GGCCTTCCCAAGGAAGCAGTGGCGCCGTTGAGCGAGTCCGTGCGGTTGGCGCCCGCTCATGTGGAGACGCGTGTCGAACT
GGCGCGCGCGTTCCTGGAGGCATCGCGCGTGGAGGAAGGGTGTCACGCCGCCGCGGAGGCGCGGGTGTACGGGCCTTGGG
ACACGGGCGCGTTGGAGGCGGGTGTGCGCTGTGAGCTGTCACGCGGCAACGTCGAGCGGGCCCTGGAGCGCCTGGTGGAA
GCGCGCCGGGTGGACCCTCAGGATGCCCGACTGCGCGCGGCGGAACTCGCGCTGCGGACGGTGCTGGAGGCTGCGCCGCA
TCGCTGA

Upstream 100 bases:

>100_bases
TTTCCCTGTACAAGCCATGTATCCCCCTCAAAAGACACGACTTTCTCCCGAGGAAGAGGGGCAGCCGAGGCTGTTGTCCA
TCGGTCAATCGGCCGGTGGA

Downstream 100 bases:

>100_bases
AACCCAGGTCGGAAAATGTAGGCGAAACTCCTGAGAATCGTCGCAGATAACCCCAATGTAGGCCGAAGGCACACGCAGAG
GGGGGACACCATGACGAGGA

Product: S54 family peptidase

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MRLGGAPWLTLILATVLVGIHGAARAAGPVGLDTLLRWGAKAGPLVVDAGQVWRLVTAHFLHRDFPHLALNVLVLLAAGS
GLERLCRRRDYAALLVAAGLATMAGSLGSSGGVSVGASGLVYACVGALLVLGRRHRAKLPARWMSSEAAVPTVLVFLWMG
WTSVGVDNAGHLGGLLAGLLAGVFLEPRWHPDTGWLRPVGMVVAAVVVTGGVVAERSVWRMERDDGFGLSVALPRDWRGD
VDGQGRRAFSNGLPGRGRATFSAEAIEAGEPGDGSVQARQFQQEVLVQGAPSPEGRTLKVTEPVAARVGGRSAQRLHAEL
EGPGGPTHLMALFVPRGEWVYRLVFTWPAAYPAYREVVDRMVAEVRFDEPSVLREARARALLVPGAPGPLRALGGVLRRL
GLPKEAVAPLSESVRLAPAHVETRVELARAFLEASRVEEGCHAAAEARVYGPWDTGALEAGVRCELSRGNVERALERLVE
ARRVDPQDARLRAAELALRTVLEAAPHR

Sequences:

>Translated_508_residues
MRLGGAPWLTLILATVLVGIHGAARAAGPVGLDTLLRWGAKAGPLVVDAGQVWRLVTAHFLHRDFPHLALNVLVLLAAGS
GLERLCRRRDYAALLVAAGLATMAGSLGSSGGVSVGASGLVYACVGALLVLGRRHRAKLPARWMSSEAAVPTVLVFLWMG
WTSVGVDNAGHLGGLLAGLLAGVFLEPRWHPDTGWLRPVGMVVAAVVVTGGVVAERSVWRMERDDGFGLSVALPRDWRGD
VDGQGRRAFSNGLPGRGRATFSAEAIEAGEPGDGSVQARQFQQEVLVQGAPSPEGRTLKVTEPVAARVGGRSAQRLHAEL
EGPGGPTHLMALFVPRGEWVYRLVFTWPAAYPAYREVVDRMVAEVRFDEPSVLREARARALLVPGAPGPLRALGGVLRRL
GLPKEAVAPLSESVRLAPAHVETRVELARAFLEASRVEEGCHAAAEARVYGPWDTGALEAGVRCELSRGNVERALERLVE
ARRVDPQDARLRAAELALRTVLEAAPHR
>Mature_508_residues
MRLGGAPWLTLILATVLVGIHGAARAAGPVGLDTLLRWGAKAGPLVVDAGQVWRLVTAHFLHRDFPHLALNVLVLLAAGS
GLERLCRRRDYAALLVAAGLATMAGSLGSSGGVSVGASGLVYACVGALLVLGRRHRAKLPARWMSSEAAVPTVLVFLWMG
WTSVGVDNAGHLGGLLAGLLAGVFLEPRWHPDTGWLRPVGMVVAAVVVTGGVVAERSVWRMERDDGFGLSVALPRDWRGD
VDGQGRRAFSNGLPGRGRATFSAEAIEAGEPGDGSVQARQFQQEVLVQGAPSPEGRTLKVTEPVAARVGGRSAQRLHAEL
EGPGGPTHLMALFVPRGEWVYRLVFTWPAAYPAYREVVDRMVAEVRFDEPSVLREARARALLVPGAPGPLRALGGVLRRL
GLPKEAVAPLSESVRLAPAHVETRVELARAFLEASRVEEGCHAAAEARVYGPWDTGALEAGVRCELSRGNVERALERLVE
ARRVDPQDARLRAAELALRTVLEAAPHR

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 54094; Mature: 54094

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGGAPWLTLILATVLVGIHGAARAAGPVGLDTLLRWGAKAGPLVVDAGQVWRLVTAHF
CCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCEEEECHHHHHHHHHHH
LHRDFPHLALNVLVLLAAGSGLERLCRRRDYAALLVAAGLATMAGSLGSSGGVSVGASGL
HHCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
VYACVGALLVLGRRHRAKLPARWMSSEAAVPTVLVFLWMGWTSVGVDNAGHLGGLLAGLL
HHHHHHHHHHHCCHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AGVFLEPRWHPDTGWLRPVGMVVAAVVVTGGVVAERSVWRMERDDGFGLSVALPRDWRGD
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCEEEEECCCCCCCC
VDGQGRRAFSNGLPGRGRATFSAEAIEAGEPGDGSVQARQFQQEVLVQGAPSPEGRTLKV
CCCCCCHHHHCCCCCCCCCEEEHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEE
TEPVAARVGGRSAQRLHAELEGPGGPTHLMALFVPRGEWVYRLVFTWPAAYPAYREVVDR
CCHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEEECCCCCCHHHHHHHHH
MVAEVRFDEPSVLREARARALLVPGAPGPLRALGGVLRRLGLPKEAVAPLSESVRLAPAH
HHHHHCCCCHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHCCCHHHHHCHHHCCEECHHH
VETRVELARAFLEASRVEEGCHAAAEARVYGPWDTGALEAGVRCELSRGNVERALERLVE
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHH
ARRVDPQDARLRAAELALRTVLEAAPHR
HHCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLGGAPWLTLILATVLVGIHGAARAAGPVGLDTLLRWGAKAGPLVVDAGQVWRLVTAHF
CCCCCCHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCEEEECHHHHHHHHHHH
LHRDFPHLALNVLVLLAAGSGLERLCRRRDYAALLVAAGLATMAGSLGSSGGVSVGASGL
HHCCCHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
VYACVGALLVLGRRHRAKLPARWMSSEAAVPTVLVFLWMGWTSVGVDNAGHLGGLLAGLL
HHHHHHHHHHHCCHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
AGVFLEPRWHPDTGWLRPVGMVVAAVVVTGGVVAERSVWRMERDDGFGLSVALPRDWRGD
HHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCEEEEECCCCCCCC
VDGQGRRAFSNGLPGRGRATFSAEAIEAGEPGDGSVQARQFQQEVLVQGAPSPEGRTLKV
CCCCCCHHHHCCCCCCCCCEEEHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEE
TEPVAARVGGRSAQRLHAELEGPGGPTHLMALFVPRGEWVYRLVFTWPAAYPAYREVVDR
CCHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEEECCCCCCHHHHHHHHH
MVAEVRFDEPSVLREARARALLVPGAPGPLRALGGVLRRLGLPKEAVAPLSESVRLAPAH
HHHHHCCCCHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHCCCHHHHHCHHHCCEECHHH
VETRVELARAFLEASRVEEGCHAAAEARVYGPWDTGALEAGVRCELSRGNVERALERLVE
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEECCCCHHHHHHHHHH
ARRVDPQDARLRAAELALRTVLEAAPHR
HHCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]