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The map label for this gene is 108762698

Identifier: 108762698

GI number: 108762698

Start: 5485659

End: 5486918

Strand: Direct

Name: 108762698

Synonym: MXAN_4435

Alternate gene names: NA

Gene position: 5485659-5486918 (Clockwise)

Preceding gene: 108763845

Following gene: 108757677

Centisome position: 60.02

GC content: 69.92

Gene sequence:

>1260_bases
ATGAACACCTCCGCCACGGAGTTCGACATCATCGCCTGGGGGGCCACCGGCTTCACCGGGCGACTGGTCGCCGAATATCT
CGCCAGGACCCAGGACAGCCACCGCGCACGGTGGGCCCTGGCGGGACGCGACCTCGACAAGCTGGAGAAGGTCCGGCAGG
GGCTGGCGGCGATTGCGCCCTCCTTCGCGGAGCTACCGCTGCTCGTCGCGGATGCACGCGACGCCGCGTCGCTGGATGCC
CTGGTCCCTCGCACCCGCGTGGTCTGCACCACGGTGGGCCCCTACGCACGTTACGGCAGCGAGCTCGTCGCGGCGTGTGT
TCGGGCCGGCGTCAGCTACTGCGACCTGACGGGTGAAGTGCAGTGGATGCGGCGGATGATTGACGCCCACCACGAGCAGG
CGCGGCAGAGCGGCGCACGCATCGTCCACACCTGTGGCTTCGACTCGATTCCGTCGGACCTGGGCGTGTTGATGATGCAG
GAGCACATGCGGGAGCACCATGGCGGGCACCTGGAAGCAGTCCGCCTCTACATGGGTCCCATGCGCGGAGGCGCTAGCGG
TGGCACGGCCGCGAGCATGGTGCAGGCGATGGAAGAAGCATCAACGGACCGCTCGGTGCGGCGAATCATGGCCCACCCGC
ATGCGCTGGACCCCGTCCCAGGCCGCTGGCGACCCGAGTCCAAGGACGCGCTGGGCGTCCACTACAGCCAGGAACTGGGC
CAGTGGACCGGCCCGTTCCTCATGGCGACCGTGAACACGCGCGTCGTCCGACGCAGCAATGCGCTGCTCGGTCACCCGTG
GGGAGAGCACTTCCGGTACGCGGAGGTCGCCAGCTATGGCGCCGGGCCCAAGGGCCTGCTGCGCGCCACGGGCGTCACCG
CGGGCCTGGGAGGCGTCGTCGCCGCGATGCAGGTGAAGCCCCTACGCACGCTGCTGGAGAAGAAGGTACTGCCCGCGCCG
GGTGAAGGCCCGTCTCTGGAAGCCCGGGAGAAAGGCTTCTTCGTCGCGCAGCTTCGTGGCGAAGGCACCTCCCCCCGCAC
GGGCAAGCAGGTGCGGCTGAAGGGCAAGGTGGCGGCGCAGGGAGACCCGGGCTACGCGGCCACGTCGCGGATGCTCGCCG
AGTCCGCGCTGTGCCTCGCCTTCGACGACACTCCGACCACGGGCGGCGTGCTCACGCCGGCCTCCGCCATGGGCATGCGA
CTGGTGGAGCGGCTGCGCCGTGCGGGCATGACGTTCGAAGTGGAGGAGCTGTCCACCTGA

Upstream 100 bases:

>100_bases
GCCCGAAGAGGAGTAACCGGGGTAGCAATCTCCGCGGCGTGAACACTCGTTTCACGCCGCGGTTGCGGTGCCTTCGGGGC
GCGACCAGACTCCCGCGCCC

Downstream 100 bases:

>100_bases
GCCATTCCGCCGCGAGCGCGCGATGTCCTACGCGCTCTTGCGGCGCCGCATCATCGCCTCGTACGAGCGGCCCACGCTCT
GCGAGAGGATGAGCAGCTCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNTSATEFDIIAWGATGFTGRLVAEYLARTQDSHRARWALAGRDLDKLEKVRQGLAAIAPSFAELPLLVADARDAASLDA
LVPRTRVVCTTVGPYARYGSELVAACVRAGVSYCDLTGEVQWMRRMIDAHHEQARQSGARIVHTCGFDSIPSDLGVLMMQ
EHMREHHGGHLEAVRLYMGPMRGGASGGTAASMVQAMEEASTDRSVRRIMAHPHALDPVPGRWRPESKDALGVHYSQELG
QWTGPFLMATVNTRVVRRSNALLGHPWGEHFRYAEVASYGAGPKGLLRATGVTAGLGGVVAAMQVKPLRTLLEKKVLPAP
GEGPSLEAREKGFFVAQLRGEGTSPRTGKQVRLKGKVAAQGDPGYAATSRMLAESALCLAFDDTPTTGGVLTPASAMGMR
LVERLRRAGMTFEVEELST

Sequences:

>Translated_419_residues
MNTSATEFDIIAWGATGFTGRLVAEYLARTQDSHRARWALAGRDLDKLEKVRQGLAAIAPSFAELPLLVADARDAASLDA
LVPRTRVVCTTVGPYARYGSELVAACVRAGVSYCDLTGEVQWMRRMIDAHHEQARQSGARIVHTCGFDSIPSDLGVLMMQ
EHMREHHGGHLEAVRLYMGPMRGGASGGTAASMVQAMEEASTDRSVRRIMAHPHALDPVPGRWRPESKDALGVHYSQELG
QWTGPFLMATVNTRVVRRSNALLGHPWGEHFRYAEVASYGAGPKGLLRATGVTAGLGGVVAAMQVKPLRTLLEKKVLPAP
GEGPSLEAREKGFFVAQLRGEGTSPRTGKQVRLKGKVAAQGDPGYAATSRMLAESALCLAFDDTPTTGGVLTPASAMGMR
LVERLRRAGMTFEVEELST
>Mature_419_residues
MNTSATEFDIIAWGATGFTGRLVAEYLARTQDSHRARWALAGRDLDKLEKVRQGLAAIAPSFAELPLLVADARDAASLDA
LVPRTRVVCTTVGPYARYGSELVAACVRAGVSYCDLTGEVQWMRRMIDAHHEQARQSGARIVHTCGFDSIPSDLGVLMMQ
EHMREHHGGHLEAVRLYMGPMRGGASGGTAASMVQAMEEASTDRSVRRIMAHPHALDPVPGRWRPESKDALGVHYSQELG
QWTGPFLMATVNTRVVRRSNALLGHPWGEHFRYAEVASYGAGPKGLLRATGVTAGLGGVVAAMQVKPLRTLLEKKVLPAP
GEGPSLEAREKGFFVAQLRGEGTSPRTGKQVRLKGKVAAQGDPGYAATSRMLAESALCLAFDDTPTTGGVLTPASAMGMR
LVERLRRAGMTFEVEELST

Specific function: Unknown

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=447, Percent_Identity=30.8724832214765, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17560066, Length=446, Percent_Identity=27.1300448430493, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI32567112, Length=240, Percent_Identity=32.5, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71991033, Length=441, Percent_Identity=26.984126984127, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24644140, Length=452, Percent_Identity=29.2035398230088, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24644142, Length=452, Percent_Identity=29.2035398230088, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21356081, Length=452, Percent_Identity=29.2035398230088, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24646278, Length=445, Percent_Identity=28.314606741573, Blast_Score=135, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 45110; Mature: 45110

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSATEFDIIAWGATGFTGRLVAEYLARTQDSHRARWALAGRDLDKLEKVRQGLAAIAP
CCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHEEEECCCCHHHHHHHHHHHHHHCC
SFAELPLLVADARDAASLDALVPRTRVVCTTVGPYARYGSELVAACVRAGVSYCDLTGEV
CHHHCCEEEECCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEECCCCHH
QWMRRMIDAHHEQARQSGARIVHTCGFDSIPSDLGVLMMQEHMREHHGGHLEAVRLYMGP
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHCC
MRGGASGGTAASMVQAMEEASTDRSVRRIMAHPHALDPVPGRWRPESKDALGVHYSQELG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHC
QWTGPFLMATVNTRVVRRSNALLGHPWGEHFRYAEVASYGAGPKGLLRATGVTAGLGGVV
CCCCCEEEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHH
AAMQVKPLRTLLEKKVLPAPGEGPSLEAREKGFFVAQLRGEGTSPRTGKQVRLKGKVAAQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCEEEEEEECCCCCCCCCCEEEEEEEEEEC
GDPGYAATSRMLAESALCLAFDDTPTTGGVLTPASAMGMRLVERLRRAGMTFEVEELST
CCCCHHHHHHHHHHCCEEEEECCCCCCCCEECCHHHHHHHHHHHHHHCCCEEEHHCCCC
>Mature Secondary Structure
MNTSATEFDIIAWGATGFTGRLVAEYLARTQDSHRARWALAGRDLDKLEKVRQGLAAIAP
CCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHEEEECCCCHHHHHHHHHHHHHHCC
SFAELPLLVADARDAASLDALVPRTRVVCTTVGPYARYGSELVAACVRAGVSYCDLTGEV
CHHHCCEEEECCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCEECCCCHH
QWMRRMIDAHHEQARQSGARIVHTCGFDSIPSDLGVLMMQEHMREHHGGHLEAVRLYMGP
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHCC
MRGGASGGTAASMVQAMEEASTDRSVRRIMAHPHALDPVPGRWRPESKDALGVHYSQELG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHC
QWTGPFLMATVNTRVVRRSNALLGHPWGEHFRYAEVASYGAGPKGLLRATGVTAGLGGVV
CCCCCEEEEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHH
AAMQVKPLRTLLEKKVLPAPGEGPSLEAREKGFFVAQLRGEGTSPRTGKQVRLKGKVAAQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCEEEEEEECCCCCCCCCCEEEEEEEEEEC
GDPGYAATSRMLAESALCLAFDDTPTTGGVLTPASAMGMRLVERLRRAGMTFEVEELST
CCCCHHHHHHHHHHCCEEEEECCCCCCCCEECCHHHHHHHHHHHHHHCCCEEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]