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The map label for this gene is sucD [H]

Identifier: 108762192

GI number: 108762192

Start: 4127956

End: 4128855

Strand: Direct

Name: sucD [H]

Synonym: MXAN_3542

Alternate gene names: 108762192

Gene position: 4127956-4128855 (Clockwise)

Preceding gene: 108761542

Following gene: 108761188

Centisome position: 45.16

GC content: 69.0

Gene sequence:

>900_bases
ATGGCCATCCTCGTCAACGAAAACACGAAGGTCCTCTGCCAGGGCATCACCGGCTCGGCGGGCTCGTTCCACGCGAAGCA
GATGCTCGAGTACGGCACGAAGCTCGTTGCCGGCGTGACTCCGGGCAAGGGCGGCACCACGTTCGAAGGCAAGGTCCCCG
TGTTCAACACGGTGGCCGAGGCGGTGAAGGAGACGGGCGCGAACACGTCCGTGGTCTTCGTGCCGCCCCCCTTCGCCGCT
GACTCCATCATGGAGGCTGCGGACGCGGGCGTGGCCCTCATCATCGTCATCACCGAGGGCATCCCGGTCAACGACATGGT
GCGCGCCAAGCGCTACCTGCAGGGCAAGCCGGGCATCCGGCTGGTCGGCCCCAACTGTCCGGGCGTCATCACCCCGGGCG
CGCTGTGCAAGATCGGCATCATGCCGGGCCACATCCACAAGCCGGGCCGCATCGGCGTGGTGTCCCGCTCCGGCACGCTG
ACCTACGAGGCCGTGCACCAGCTCACCCAGCTGGGCCTGGGCCAGTCCACCGCCGTGGGCATCGGCGGTGACCCGGTCAA
CGGCACGGACTTCGTGGACGTGCTGAAGCTCTTCAACGCGGACCCGGACACCGACGCCGTCATCATGATTGGCGAAATCG
GCGGTGACGCCGAGGAGCGCGGCGCCGAGTACGTGGCGCGCGAGTTCACCAAGCCCATCGCCGGGTTCATCGCGGGCCAG
TCCGCGCCCCCGGGCAAGCGCATGGGCCACGCCGGCGCCATCATCTCCGGCGGCAAGGGCACGGCGACCGAGAAGATCAA
GGCCATGGAGGCCGCGGGCATCCTGATGGCCGCCAGCCCCGCCGAGCTGGGCACCACCCTTCAGGAGGCCCTCAAGCGGG
GCGCTCCGAAGAAGCGCTAA

Upstream 100 bases:

>100_bases
CCGGCCTCGCCATCACCCCGGCGGACAACCTGCGTCAGGCGGCGGAGAAGGCCGTCGCTGCGGTGAAGTAATCCCGCGCA
CTCTTTCCTGAAAGAACGCC

Downstream 100 bases:

>100_bases
ACCCCAACGGAAACACGAGAAGGAGCCAGTCACATGGCTATCGAGCGTACGCTGTCCATCATCAAGCCGGACGGCCTGGA
GAAGGGCGTCATCGGGAAGA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MAILVNENTKVLCQGITGSAGSFHAKQMLEYGTKLVAGVTPGKGGTTFEGKVPVFNTVAEAVKETGANTSVVFVPPPFAA
DSIMEAADAGVALIIVITEGIPVNDMVRAKRYLQGKPGIRLVGPNCPGVITPGALCKIGIMPGHIHKPGRIGVVSRSGTL
TYEAVHQLTQLGLGQSTAVGIGGDPVNGTDFVDVLKLFNADPDTDAVIMIGEIGGDAEERGAEYVAREFTKPIAGFIAGQ
SAPPGKRMGHAGAIISGGKGTATEKIKAMEAAGILMAASPAELGTTLQEALKRGAPKKR

Sequences:

>Translated_299_residues
MAILVNENTKVLCQGITGSAGSFHAKQMLEYGTKLVAGVTPGKGGTTFEGKVPVFNTVAEAVKETGANTSVVFVPPPFAA
DSIMEAADAGVALIIVITEGIPVNDMVRAKRYLQGKPGIRLVGPNCPGVITPGALCKIGIMPGHIHKPGRIGVVSRSGTL
TYEAVHQLTQLGLGQSTAVGIGGDPVNGTDFVDVLKLFNADPDTDAVIMIGEIGGDAEERGAEYVAREFTKPIAGFIAGQ
SAPPGKRMGHAGAIISGGKGTATEKIKAMEAAGILMAASPAELGTTLQEALKRGAPKKR
>Mature_298_residues
AILVNENTKVLCQGITGSAGSFHAKQMLEYGTKLVAGVTPGKGGTTFEGKVPVFNTVAEAVKETGANTSVVFVPPPFAAD
SIMEAADAGVALIIVITEGIPVNDMVRAKRYLQGKPGIRLVGPNCPGVITPGALCKIGIMPGHIHKPGRIGVVSRSGTLT
YEAVHQLTQLGLGQSTAVGIGGDPVNGTDFVDVLKLFNADPDTDAVIMIGEIGGDAEERGAEYVAREFTKPIAGFIAGQS
APPGKRMGHAGAIISGGKGTATEKIKAMEAAGILMAASPAELGTTLQEALKRGAPKKR

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=295, Percent_Identity=61.6949152542373, Blast_Score=320, Evalue=7e-88,
Organism=Homo sapiens, GI38569423, Length=255, Percent_Identity=30.1960784313725, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI38569421, Length=255, Percent_Identity=30.1960784313725, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI1786949, Length=292, Percent_Identity=63.3561643835616, Blast_Score=376, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17553126, Length=293, Percent_Identity=57.679180887372, Blast_Score=318, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17550194, Length=291, Percent_Identity=58.0756013745705, Blast_Score=318, Evalue=3e-87,
Organism=Caenorhabditis elegans, GI17557344, Length=255, Percent_Identity=28.2352941176471, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551266, Length=252, Percent_Identity=27.3809523809524, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324716, Length=298, Percent_Identity=47.6510067114094, Blast_Score=264, Evalue=1e-71,
Organism=Drosophila melanogaster, GI21356559, Length=293, Percent_Identity=55.6313993174061, Blast_Score=331, Evalue=4e-91,
Organism=Drosophila melanogaster, GI28574296, Length=293, Percent_Identity=59.0443686006826, Blast_Score=314, Evalue=4e-86,
Organism=Drosophila melanogaster, GI281363477, Length=252, Percent_Identity=28.968253968254, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI281363475, Length=252, Percent_Identity=28.968253968254, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI281363473, Length=252, Percent_Identity=28.968253968254, Blast_Score=94, Evalue=8e-20,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30622; Mature: 30491

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVNENTKVLCQGITGSAGSFHAKQMLEYGTKLVAGVTPGKGGTTFEGKVPVFNTVAE
CEEEEECCCEEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCCCCEECCCCCHHHHHHH
AVKETGANTSVVFVPPPFAADSIMEAADAGVALIIVITEGIPVNDMVRAKRYLQGKPGIR
HHHHCCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEE
LVGPNCPGVITPGALCKIGIMPGHIHKPGRIGVVSRSGTLTYEAVHQLTQLGLGQSTAVG
EECCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEE
IGGDPVNGTDFVDVLKLFNADPDTDAVIMIGEIGGDAEERGAEYVAREFTKPIAGFIAGQ
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
SAPPGKRMGHAGAIISGGKGTATEKIKAMEAAGILMAASPAELGTTLQEALKRGAPKKR
CCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AILVNENTKVLCQGITGSAGSFHAKQMLEYGTKLVAGVTPGKGGTTFEGKVPVFNTVAE
EEEEECCCEEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCCCCEECCCCCHHHHHHH
AVKETGANTSVVFVPPPFAADSIMEAADAGVALIIVITEGIPVNDMVRAKRYLQGKPGIR
HHHHCCCCCEEEEECCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEE
LVGPNCPGVITPGALCKIGIMPGHIHKPGRIGVVSRSGTLTYEAVHQLTQLGLGQSTAVG
EECCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEE
IGGDPVNGTDFVDVLKLFNADPDTDAVIMIGEIGGDAEERGAEYVAREFTKPIAGFIAGQ
CCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
SAPPGKRMGHAGAIISGGKGTATEKIKAMEAAGILMAASPAELGTTLQEALKRGAPKKR
CCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA