Click here to switch to the map view.

The map label for this gene is spoT [H]

Identifier: 108761833

GI number: 108761833

Start: 1602568

End: 1602990

Strand: Reverse

Name: spoT [H]

Synonym: MXAN_1364

Alternate gene names: 108761833

Gene position: 1602990-1602568 (Counterclockwise)

Preceding gene: 108763155

Following gene: 108759652

Centisome position: 17.54

GC content: 71.87

Gene sequence:

>423_bases
ATGCCCGCACTCGAAGACGCCATCGCGCTCGCGGTGGCCGCGCATCAGGGCCAGCGAGACAAGGCCGGCCAGACGTACAT
CCTCCACCCGCTGCGGGTGATGATGCGGCTGGACACGGACGAAGAGCGCACCGTGGCCATCCTCCACGACGTGGTGGAGG
ACACGCCCTACACGCTCGAGCGCCTGCGCGAGCTGGGCTACGCGGAAAACGTCCTGGGCGCGCTGGACGCGCTCACCCGC
CGCCAGGACGAGACGTACGAGGCCTTCATCGAACGGCTGCGCCCGCTGGCGCTCGCCCGCCGCGTGAAGCTGGCGGACCT
TGAGGACAACATGGACGTGCGGCGGCTGGCAGCGGTGACGCCCAAGGACGCCGAGCGCCTGGCCCGCTACCGCGCCGCCT
GGGCCCGCCTGCGCGAGCCCTAG

Upstream 100 bases:

>100_bases
CGCCTGCCGCCACGAGAACGCGGCCAGTTGCCTGCCGTGATGACGTGAAGGCCGCCCTCCCCGCTCGCCTGGGGAGGGCG
TCTGGCGTTAGAAGACGGGC

Downstream 100 bases:

>100_bases
AAGACACGACGGCCCGGAGCGCCACGGGGGCGACTCCGGGCCGTAGTGCTACCAGCGCCCGCCGAGGAAAGCAGGGTGCC
GGTTCCTTCCTCTCCGCGCT

Product: hypothetical protein

Products: NA

Alternate protein names: Penta-phosphate guanosine-3'-pyrophosphohydrolase; (ppGpp)ase [H]

Number of amino acids: Translated: 140; Mature: 139

Protein sequence:

>140_residues
MPALEDAIALAVAAHQGQRDKAGQTYILHPLRVMMRLDTDEERTVAILHDVVEDTPYTLERLRELGYAENVLGALDALTR
RQDETYEAFIERLRPLALARRVKLADLEDNMDVRRLAAVTPKDAERLARYRAAWARLREP

Sequences:

>Translated_140_residues
MPALEDAIALAVAAHQGQRDKAGQTYILHPLRVMMRLDTDEERTVAILHDVVEDTPYTLERLRELGYAENVLGALDALTR
RQDETYEAFIERLRPLALARRVKLADLEDNMDVRRLAAVTPKDAERLARYRAAWARLREP
>Mature_139_residues
PALEDAIALAVAAHQGQRDKAGQTYILHPLRVMMRLDTDEERTVAILHDVVEDTPYTLERLRELGYAENVLGALDALTRR
QDETYEAFIERLRPLALARRVKLADLEDNMDVRRLAAVTPKDAERLARYRAAWARLREP

Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the degradation of ppGpp into G

COG id: COG0317

COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR003607
- InterPro:   IPR007685
- InterPro:   IPR004811
- InterPro:   IPR004095
- InterPro:   IPR012676 [H]

Pfam domain/function: PF04607 RelA_SpoT; PF02824 TGS [H]

EC number: =3.1.7.2 [H]

Molecular weight: Translated: 16048; Mature: 15916

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALEDAIALAVAAHQGQRDKAGQTYILHPLRVMMRLDTDEERTVAILHDVVEDTPYTLE
CCCHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHH
RLRELGYAENVLGALDALTRRQDETYEAFIERLRPLALARRVKLADLEDNMDVRRLAAVT
HHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
PKDAERLARYRAAWARLREP
CHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PALEDAIALAVAAHQGQRDKAGQTYILHPLRVMMRLDTDEERTVAILHDVVEDTPYTLE
CCHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHH
RLRELGYAENVLGALDALTRRQDETYEAFIERLRPLALARRVKLADLEDNMDVRRLAAVT
HHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
PKDAERLARYRAAWARLREP
CHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]