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The map label for this gene is sucC

Identifier: 108761542

GI number: 108761542

Start: 4126766

End: 4127926

Strand: Direct

Name: sucC

Synonym: MXAN_3541

Alternate gene names: 108761542

Gene position: 4126766-4127926 (Clockwise)

Preceding gene: 108757195

Following gene: 108762192

Centisome position: 45.15

GC content: 65.29

Gene sequence:

>1161_bases
ATGAAGATCCACGAGTACCAGGGCAAGGAAATCTTCCGGAAGTACGGCGTGCCCACGCCGAAGGGCATCCTCGCCGTTTC
CGCCAACGACGCGGAGGCCGCCGCGAAGGAGCTCGGCACTTCTGTGGTCGTCGTGAAGGCCCAGATCCACGCAGGTGGCC
GTGGCAAGGGCGGCGGCGTGAAGCTGGCCAAGAGCCCCGCGGAAGCCAAGGAGCTGGCCAAGCAGATGCTTGGCATGAAG
CTCAAGACCATCCAGACCGGGCCGGAAGGCCAGACGGTCCACAAGGTCTACATCGAAGAAGGTCTCGCCATTGGCCAGGA
GCTGTACCTGGGCGTGACGCTGGACCGCGCCACCAGCCGCATCACCTTCATGGCCTCCCGCGAGGGCGGCGTGGAGATTG
AAGAGGTGGCGGAGAAGCACCCGGAGAAGATCCTCCGCGAGTCGGTGGACCCGGCCGTGGGCTTCCAGGACTTCCAGGGC
CGCAAGCTGGCCTTCGGGCTGGGCCTGACGGGCCCCACGGTGAACAAGTTCACCCAATTCTGCTCGGCGCTGTACCGGAT
GTTCATGGACACGGACGCCTCGCTCGTGGAGATCAACCCGCTGGTCATCCTGAAGGATGGCGGCGTGGTGGCGCTCGACG
CGAAGGTGACCTTCGACGAGAACGCGCTCTACCGGCACAAGGACCTGCTGGAGTACCGCGACCTGGCCGAAGAGGAGCCC
CGTGAGATCCAGGCCAAGGAGTGGGATCTGGCCTACATCGCGCTGGATGGCAACATCGGCTGCATGGTGAACGGCGCCGG
CCTGGCGATGGCCACCATGGACACCATCAAGCTGGTGGGCGGCAGTCCGGCCAACTTCCTGGACGTGGGCGGCGGCGCCA
ACAAGGAGAAGGTCACCGCGGCCTTCAAGCTCATCCTGGCGGACCCGGCCGTGAAGGCGGTGCTGGTCAACATCTTTGGC
GGCATCATGAAGTGCGACGTCATCGCCGAGGGCATCATCGCCGCGGCGAAGGAGGTCCAGCTCAAGGTTCCGCTCGTGGT
GCGGCTGGAAGGCACCAACGTTGAGAAGGGCAAGGAGCTGCTGAGCAACTCCGGCCTCGCCATCACCCCGGCGGACAACC
TGCGTCAGGCGGCGGAGAAGGCCGTCGCTGCGGTGAAGTAA

Upstream 100 bases:

>100_bases
CGGGGTCAAACGGTCTTGCACTCCGTCCTTTTCTGCGCAATGAGGGCCCGGCGCTGACGCCTCTGTTCAGGCTGTCTCCC
TCGTCTCCACCGGAGCCTCG

Downstream 100 bases:

>100_bases
TCCCGCGCACTCTTTCCTGAAAGAACGCCATGGCCATCCTCGTCAACGAAAACACGAAGGTCCTCTGCCAGGGCATCACC
GGCTCGGCGGGCTCGTTCCA

Product: succinyl-CoA synthase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MKIHEYQGKEIFRKYGVPTPKGILAVSANDAEAAAKELGTSVVVVKAQIHAGGRGKGGGVKLAKSPAEAKELAKQMLGMK
LKTIQTGPEGQTVHKVYIEEGLAIGQELYLGVTLDRATSRITFMASREGGVEIEEVAEKHPEKILRESVDPAVGFQDFQG
RKLAFGLGLTGPTVNKFTQFCSALYRMFMDTDASLVEINPLVILKDGGVVALDAKVTFDENALYRHKDLLEYRDLAEEEP
REIQAKEWDLAYIALDGNIGCMVNGAGLAMATMDTIKLVGGSPANFLDVGGGANKEKVTAAFKLILADPAVKAVLVNIFG
GIMKCDVIAEGIIAAAKEVQLKVPLVVRLEGTNVEKGKELLSNSGLAITPADNLRQAAEKAVAAVK

Sequences:

>Translated_386_residues
MKIHEYQGKEIFRKYGVPTPKGILAVSANDAEAAAKELGTSVVVVKAQIHAGGRGKGGGVKLAKSPAEAKELAKQMLGMK
LKTIQTGPEGQTVHKVYIEEGLAIGQELYLGVTLDRATSRITFMASREGGVEIEEVAEKHPEKILRESVDPAVGFQDFQG
RKLAFGLGLTGPTVNKFTQFCSALYRMFMDTDASLVEINPLVILKDGGVVALDAKVTFDENALYRHKDLLEYRDLAEEEP
REIQAKEWDLAYIALDGNIGCMVNGAGLAMATMDTIKLVGGSPANFLDVGGGANKEKVTAAFKLILADPAVKAVLVNIFG
GIMKCDVIAEGIIAAAKEVQLKVPLVVRLEGTNVEKGKELLSNSGLAITPADNLRQAAEKAVAAVK
>Mature_386_residues
MKIHEYQGKEIFRKYGVPTPKGILAVSANDAEAAAKELGTSVVVVKAQIHAGGRGKGGGVKLAKSPAEAKELAKQMLGMK
LKTIQTGPEGQTVHKVYIEEGLAIGQELYLGVTLDRATSRITFMASREGGVEIEEVAEKHPEKILRESVDPAVGFQDFQG
RKLAFGLGLTGPTVNKFTQFCSALYRMFMDTDASLVEINPLVILKDGGVVALDAKVTFDENALYRHKDLLEYRDLAEEEP
REIQAKEWDLAYIALDGNIGCMVNGAGLAMATMDTIKLVGGSPANFLDVGGGANKEKVTAAFKLILADPAVKAVLVNIFG
GIMKCDVIAEGIIAAAKEVQLKVPLVVRLEGTNVEKGKELLSNSGLAITPADNLRQAAEKAVAAVK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=47.5578406169666, Blast_Score=359, Evalue=2e-99,
Organism=Homo sapiens, GI157779135, Length=381, Percent_Identity=49.0813648293963, Blast_Score=357, Evalue=1e-98,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=49.0358126721763, Blast_Score=338, Evalue=4e-93,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=54.6632124352332, Blast_Score=412, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=45.9390862944162, Blast_Score=341, Evalue=5e-94,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=46.6666666666667, Blast_Score=332, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=44.1326530612245, Blast_Score=343, Evalue=3e-95,
Organism=Drosophila melanogaster, GI161078106, Length=389, Percent_Identity=47.5578406169666, Blast_Score=346, Evalue=1e-95,
Organism=Drosophila melanogaster, GI24645208, Length=389, Percent_Identity=47.5578406169666, Blast_Score=346, Evalue=1e-95,
Organism=Drosophila melanogaster, GI281361397, Length=390, Percent_Identity=47.4358974358974, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI281361395, Length=390, Percent_Identity=47.4358974358974, Blast_Score=343, Evalue=1e-94,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=46.969696969697, Blast_Score=330, Evalue=7e-91,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_MYXXD (Q1D6I9)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_631734.1
- ProteinModelPortal:   Q1D6I9
- SMR:   Q1D6I9
- STRING:   Q1D6I9
- GeneID:   4101092
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_3541
- TIGR:   MXAN_3541
- eggNOG:   COG0045
- HOGENOM:   HBG315432
- OMA:   ITEVNIN
- PhylomeDB:   Q1D6I9
- BioCyc:   MXAN246197:MXAN_3541-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41188; Mature: 41188

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQGKEIFRKYGVPTPKGILAVSANDAEAAAKELGTSVVVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHCCCCCCCCEEEEECCCHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KLAKSPAEAKELAKQMLGMKLKTIQTGPEGQTVHKVYIEEGLAIGQELYLGVTLDRATSR
EEECCCHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEHHHHHCCCEEEEEEEEECCCCE
ITFMASREGGVEIEEVAEKHPEKILRESVDPAVGFQDFQGRKLAFGLGLTGPTVNKFTQF
EEEEECCCCCCCHHHHHHHCHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
CSALYRMFMDTDASLVEINPLVILKDGGVVALDAKVTFDENALYRHKDLLEYRDLAEEEP
HHHHHHHHHCCCCCEEEECCEEEEECCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCC
REIQAKEWDLAYIALDGNIGCMVNGAGLAMATMDTIKLVGGSPANFLDVGGGANKEKVTA
CCCCCCCCEEEEEEEECCEEEEEECCCEEEEEHHEEEEECCCCCCEEECCCCCCHHHHHH
AFKLILADPAVKAVLVNIFGGIMKCDVIAEGIIAAAKEVQLKVPLVVRLEGTNVEKGKEL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEEECCCCHHHHHH
LSNSGLAITPADNLRQAAEKAVAAVK
HHCCCEEEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIHEYQGKEIFRKYGVPTPKGILAVSANDAEAAAKELGTSVVVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHCCCCCCCCEEEEECCCHHHHHHHCCCEEEEEEEEEECCCCCCCCCE
KLAKSPAEAKELAKQMLGMKLKTIQTGPEGQTVHKVYIEEGLAIGQELYLGVTLDRATSR
EEECCCHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEHHHHHCCCEEEEEEEEECCCCE
ITFMASREGGVEIEEVAEKHPEKILRESVDPAVGFQDFQGRKLAFGLGLTGPTVNKFTQF
EEEEECCCCCCCHHHHHHHCHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
CSALYRMFMDTDASLVEINPLVILKDGGVVALDAKVTFDENALYRHKDLLEYRDLAEEEP
HHHHHHHHHCCCCCEEEECCEEEEECCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCC
REIQAKEWDLAYIALDGNIGCMVNGAGLAMATMDTIKLVGGSPANFLDVGGGANKEKVTA
CCCCCCCCEEEEEEEECCEEEEEECCCEEEEEHHEEEEECCCCCCEEECCCCCCHHHHHH
AFKLILADPAVKAVLVNIFGGIMKCDVIAEGIIAAAKEVQLKVPLVVRLEGTNVEKGKEL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEEECCCCHHHHHH
LSNSGLAITPADNLRQAAEKAVAAVK
HHCCCEEEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA