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The map label for this gene is hflX [H]

Identifier: 108761357

GI number: 108761357

Start: 1590937

End: 1592589

Strand: Reverse

Name: hflX [H]

Synonym: MXAN_1356

Alternate gene names: 108761357

Gene position: 1592589-1590937 (Counterclockwise)

Preceding gene: 108759652

Following gene: 108760088

Centisome position: 17.42

GC content: 68.97

Gene sequence:

>1653_bases
TTGAAGGAAATCTACGGCAACACCCTGGGCCTCAAGTCGAGCGAACAGCACCGGTTGCGCAACACCTTCCGCCGGCGCGT
CCCACCGCACGAAATCGTGTCGCCCGAGCTTGCCCGGCATCTCACCGAGCTGTCGCGTGAGCTGAACCGGCAGGTGGGTG
TGCTCGTCAACCGGAAGGGAGAAATCGAGCACGTCATCGTGGGCAACGCTCACAAGCTCGAGCTCCCGGACATCGGCCGC
GCCCGCGCGGGCCAGGTGCGTCTGCGTGGCCTCCGCCTGGTCCACACCCACTTGAAGGGCGAGCCGCTCACCAAGGACGA
CCTCACGGACCTCGCGCTGCTGCGCCTGGACTGCGTGGCGGCCGTTGGCGTGGGCCACGAAGGCCTGCCCGGCGTCCTGC
ACTACGCCTACCTCATCCCGGAGAACGGCTCCGGCGACTTCTGGCACGTCGAGACGCTGCCCTCCGTCCACGTGGCGCAG
CCGGACCTCATGGACACGCTGGGCGCGCTGGAGGAGGAGTTCAACCGCAAGGCGGCGTCGCGCAAGGTGGGCGGCCGTGA
GAAGGCCATCCTCGTGGCGGTGTGCCTGGACGGCAACCGCGCCCTGGCCGAGTCCAGCCTGGCGGAGCTGAAGGAGCTGG
CGCGCACCGCGGGCGTGGAGGTCATCGACTCCGTGCTCCAGGTGAAGCGCGAGGCGGACCCGCGCTACCTCATCGGCCGC
GGCAAGCTGGAGGAGCTCAACCTGCGCTCCATGCAGACCATGGTGGACCTGCTCATCTTCGACAAGGACCTCACCCCGTC
CCAGGGCCGCCACATCGGCGAGGCCACCAGCCTCAAGATCCTGGACCGCTCACAGCTCATCCTCGACATCTTCGCGCAGC
GCGCGCAGAGCGCCGAGGGCAAGCTCCAGGTGGAGCTGGCACAACTGAAGTACCGGCTGCCACGGCTGGTGCAGAGCGAC
GATTCGCTCAGCCGGCTCATGGGCGGCATTGGCGGACGAGGCCCAGGCGAGACGAAGCTGGAGATCGACCGCCGCCGCGT
GCGCGAGCGAATCACCCACCTGGAGAAGCGCATCGACGCGATTGGCCGGGAGCGCAGCGTGCGCCGGGCCCAGCGCAACC
GGCGCGAACTGCCCGTCATCTCCATTGTCGGCTACACCAACGCCGGCAAGTCCACGCTCCTCAACGCGATTACGAACGCA
GAGGTGCTGGCGGAGAACAAGCTGTTCGCCACGCTGGACCCCACCAGCCGGCGGCTGCGCTTCCCGCAGGAGCGGGAGGT
CATCATCACCGACACGGTGGGCTTCATCCGGGACCTGCCCAAGGACCTGGTCGCCGCCTTCCGCGCCACGCTGGAGGAGC
TGTACGACGCCAGCCTGCTGCTCCACGTCGTGGACGCGGCGGACCCCGCCCGCGACGAGCAGGTGGAGGCGGTGGAGAAC
ATCCTCGAGTCGCTCGACTTGATGGAGAAGCCGCGCCTCATGGTGTGGAACAAGGCGGACCTGCTTCCGCCGGACGAAGT
GGCGGCGCTGCTGCGCACGCGGGGCGGCGTGGCCATCAGCGCCGCGACCCGCGAGGGCCTGGCGACGCTGCTGGCCAAGG
CGGACACCACGCTGTTCGCCGAAGGCGCCACCGAGGCCATCGGCGCCATCTGA

Upstream 100 bases:

>100_bases
ATGGAAGACGCGCGCGTCCGGCGTGTTTTCCCCACAGCGGCAGTCATAAAGTCGTACGAAAAAGGTGGGGGCCCCAATGC
CTCCGCCAGGAGAGCACGGT

Downstream 100 bases:

>100_bases
GCCCGCGGTTGCCGCGCAGGCACGGCTCCCCGTAGAGTCGGGGGGCCGTGTCGACTCCATCGCTCACACCCCTGCTGCTG
GCCCAGGCTGACTACGCGAA

Product: putative GTP-binding protein HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MKEIYGNTLGLKSSEQHRLRNTFRRRVPPHEIVSPELARHLTELSRELNRQVGVLVNRKGEIEHVIVGNAHKLELPDIGR
ARAGQVRLRGLRLVHTHLKGEPLTKDDLTDLALLRLDCVAAVGVGHEGLPGVLHYAYLIPENGSGDFWHVETLPSVHVAQ
PDLMDTLGALEEEFNRKAASRKVGGREKAILVAVCLDGNRALAESSLAELKELARTAGVEVIDSVLQVKREADPRYLIGR
GKLEELNLRSMQTMVDLLIFDKDLTPSQGRHIGEATSLKILDRSQLILDIFAQRAQSAEGKLQVELAQLKYRLPRLVQSD
DSLSRLMGGIGGRGPGETKLEIDRRRVRERITHLEKRIDAIGRERSVRRAQRNRRELPVISIVGYTNAGKSTLLNAITNA
EVLAENKLFATLDPTSRRLRFPQEREVIITDTVGFIRDLPKDLVAAFRATLEELYDASLLLHVVDAADPARDEQVEAVEN
ILESLDLMEKPRLMVWNKADLLPPDEVAALLRTRGGVAISAATREGLATLLAKADTTLFAEGATEAIGAI

Sequences:

>Translated_550_residues
MKEIYGNTLGLKSSEQHRLRNTFRRRVPPHEIVSPELARHLTELSRELNRQVGVLVNRKGEIEHVIVGNAHKLELPDIGR
ARAGQVRLRGLRLVHTHLKGEPLTKDDLTDLALLRLDCVAAVGVGHEGLPGVLHYAYLIPENGSGDFWHVETLPSVHVAQ
PDLMDTLGALEEEFNRKAASRKVGGREKAILVAVCLDGNRALAESSLAELKELARTAGVEVIDSVLQVKREADPRYLIGR
GKLEELNLRSMQTMVDLLIFDKDLTPSQGRHIGEATSLKILDRSQLILDIFAQRAQSAEGKLQVELAQLKYRLPRLVQSD
DSLSRLMGGIGGRGPGETKLEIDRRRVRERITHLEKRIDAIGRERSVRRAQRNRRELPVISIVGYTNAGKSTLLNAITNA
EVLAENKLFATLDPTSRRLRFPQEREVIITDTVGFIRDLPKDLVAAFRATLEELYDASLLLHVVDAADPARDEQVEAVEN
ILESLDLMEKPRLMVWNKADLLPPDEVAALLRTRGGVAISAATREGLATLLAKADTTLFAEGATEAIGAI
>Mature_550_residues
MKEIYGNTLGLKSSEQHRLRNTFRRRVPPHEIVSPELARHLTELSRELNRQVGVLVNRKGEIEHVIVGNAHKLELPDIGR
ARAGQVRLRGLRLVHTHLKGEPLTKDDLTDLALLRLDCVAAVGVGHEGLPGVLHYAYLIPENGSGDFWHVETLPSVHVAQ
PDLMDTLGALEEEFNRKAASRKVGGREKAILVAVCLDGNRALAESSLAELKELARTAGVEVIDSVLQVKREADPRYLIGR
GKLEELNLRSMQTMVDLLIFDKDLTPSQGRHIGEATSLKILDRSQLILDIFAQRAQSAEGKLQVELAQLKYRLPRLVQSD
DSLSRLMGGIGGRGPGETKLEIDRRRVRERITHLEKRIDAIGRERSVRRAQRNRRELPVISIVGYTNAGKSTLLNAITNA
EVLAENKLFATLDPTSRRLRFPQEREVIITDTVGFIRDLPKDLVAAFRATLEELYDASLLLHVVDAADPARDEQVEAVEN
ILESLDLMEKPRLMVWNKADLLPPDEVAALLRTRGGVAISAATREGLATLLAKADTTLFAEGATEAIGAI

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=227, Percent_Identity=36.1233480176211, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI310133118, Length=237, Percent_Identity=35.4430379746835, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI310124269, Length=213, Percent_Identity=37.0892018779343, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI310124267, Length=213, Percent_Identity=37.0892018779343, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI310124171, Length=213, Percent_Identity=37.0892018779343, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI310124169, Length=213, Percent_Identity=37.0892018779343, Blast_Score=125, Evalue=9e-29,
Organism=Escherichia coli, GI1790615, Length=316, Percent_Identity=46.8354430379747, Blast_Score=278, Evalue=5e-76,
Organism=Caenorhabditis elegans, GI17561038, Length=338, Percent_Identity=29.2899408284024, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24650079, Length=316, Percent_Identity=33.5443037974684, Blast_Score=128, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 60968; Mature: 60968

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIYGNTLGLKSSEQHRLRNTFRRRVPPHEIVSPELARHLTELSRELNRQVGVLVNRKG
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHCEEECCCC
EIEHVIVGNAHKLELPDIGRARAGQVRLRGLRLVHTHLKGEPLTKDDLTDLALLRLDCVA
CEEEEEECCCEEECCCCCCCCCCCHHHHHHHHEEHHHCCCCCCCHHHHHHHHHHHHHHHH
AVGVGHEGLPGVLHYAYLIPENGSGDFWHVETLPSVHVAQPDLMDTLGALEEEFNRKAAS
HHCCCCCCCCHHEEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RKVGGREKAILVAVCLDGNRALAESSLAELKELARTAGVEVIDSVLQVKREADPRYLIGR
HCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
GKLEELNLRSMQTMVDLLIFDKDLTPSQGRHIGEATSLKILDRSQLILDIFAQRAQSAEG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCC
KLQVELAQLKYRLPRLVQSDDSLSRLMGGIGGRGPGETKLEIDRRRVRERITHLEKRIDA
CEEEHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGRERSVRRAQRNRRELPVISIVGYTNAGKSTLLNAITNAEVLAENKLFATLDPTSRRLR
HHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCHHHHCCCCEEEEECCCHHHCC
FPQEREVIITDTVGFIRDLPKDLVAAFRATLEELYDASLLLHVVDAADPARDEQVEAVEN
CCCCCCEEEECCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ILESLDLMEKPRLMVWNKADLLPPDEVAALLRTRGGVAISAATREGLATLLAKADTTLFA
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCEEE
EGATEAIGAI
CCCHHHHCCC
>Mature Secondary Structure
MKEIYGNTLGLKSSEQHRLRNTFRRRVPPHEIVSPELARHLTELSRELNRQVGVLVNRKG
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHCEEECCCC
EIEHVIVGNAHKLELPDIGRARAGQVRLRGLRLVHTHLKGEPLTKDDLTDLALLRLDCVA
CEEEEEECCCEEECCCCCCCCCCCHHHHHHHHEEHHHCCCCCCCHHHHHHHHHHHHHHHH
AVGVGHEGLPGVLHYAYLIPENGSGDFWHVETLPSVHVAQPDLMDTLGALEEEFNRKAAS
HHCCCCCCCCHHEEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RKVGGREKAILVAVCLDGNRALAESSLAELKELARTAGVEVIDSVLQVKREADPRYLIGR
HCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
GKLEELNLRSMQTMVDLLIFDKDLTPSQGRHIGEATSLKILDRSQLILDIFAQRAQSAEG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCC
KLQVELAQLKYRLPRLVQSDDSLSRLMGGIGGRGPGETKLEIDRRRVRERITHLEKRIDA
CEEEHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IGRERSVRRAQRNRRELPVISIVGYTNAGKSTLLNAITNAEVLAENKLFATLDPTSRRLR
HHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCHHHHCCCCEEEEECCCHHHCC
FPQEREVIITDTVGFIRDLPKDLVAAFRATLEELYDASLLLHVVDAADPARDEQVEAVEN
CCCCCCEEEECCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ILESLDLMEKPRLMVWNKADLLPPDEVAALLRTRGGVAISAATREGLATLLAKADTTLFA
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCEEE
EGATEAIGAI
CCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]