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The map label for this gene is grsB [H]

Identifier: 108761156

GI number: 108761156

Start: 1511191

End: 1517517

Strand: Reverse

Name: grsB [H]

Synonym: MXAN_1291

Alternate gene names: 108761156

Gene position: 1517517-1511191 (Counterclockwise)

Preceding gene: 108762941

Following gene: 108760159

Centisome position: 16.6

GC content: 69.7

Gene sequence:

>6327_bases
TTGGGACCGCGCCGCCGCGTTGCTCTGAGCTTCGTTCGCGCCATGCCCCATTCCATCGCCAGCACCGTCCCGGAGGCAGG
TCCACCGCTGGACGTCGTCGAACTCTTCGTCCGGCAGGCATCACGCACCCCACATCGGGTCGCGATATCGACGGGAACCG
TCCAGCTCACCTATCAAGAGCTCGAGCGGCGCGCGCGGTCCCTGCACGCGCGGCTCGGGTTGCTCGGGGCAGTCCCCCAG
ACGCCGGTGGGCGTCTTCGCCGAGCGCACTCCCGAGGCGCTGGTAGCGGCGCTCGCCGTGCTCATGGCCGGCTGCGTCTA
CGTCCCCATCGATCCGGCATACCCCACCGAGCGCATCGACTACATGCTCCAGGACAGTGGCGCGCCGCTCGTTCTCGGGC
CCCACACGCACCGCGACACCAGGAACCTCGCCGCGCGATTCCTCGCACTCGACGAGGAGAACGCGCCCCCCACCTCACTT
CCAGAAGCCCGCCAGGCGCCACCCCATCCTGAGTCACTCGCCTACATCATCTACACGTCGGGCTCCACGGGACTCCCCAA
GGGGGTGATGGTCGAGCACGGCGGGTTGCTCAACCTCGTCCTGGACCACGTCGCAGCGTTCGATGTCGTCCCCGAGGACC
GGGTCCTGCTCGTCACGTCGCCGTCCTTCGACGCGTCGATGTTCCAGCTGTTCATCACCTGGGCGACAGGCGCCACCCTG
CTCCTCCCCCCGGAGCACGTTGTCGCAGACCCCGATGCGATGGTCGGCTGGCTCAACGAACACCGGGCCACGCTCCTGTC
CATGCCTCCCGCGTATTTGCATGCACTGGGCCGGCGGCCCATTCCTTCGGTGCGCCTGGTCAACACCGGAGGTGACGCCC
CCATCGAGGAGGATGCCCTCCACTACGCACGGACGTGTCGCTATGTCAGTACGTACGGGCCCACCGAGACGACCATCTGC
TCGGCCTATCACGAGGTCCACGCAGACGCGTCATTCCCAGAAGGCATCCCCCTGGGGCGTCCTGTCCGAAACGCCTCGAT
GTTCGTCCTCGATGAGGCGGGAGGCATCTGCCCACCGGGCCAGCTCGGAGAGCTCTGCATCGCCGGCCAGGGCGTCTCAC
GTGGCTATCACGCCCGCCCCGAGCTCACGGCGCAGAAGTTCGTTCCCCACCCGTACCACCCCGGCGCGCGGGCATACCGC
ACGGGCGACCTCGGCTATCAGCGGTCAGACGGCGTCTTCTTCTTCCGTGGGCGCGTGGACCGGCAGGTCAAGATTCGGGG
TTATCGAGTGGAGCCCGAGGAGGTCGAGTCGCGGCTCCAGGCGCTCGAAGGCGTCGAGCGTGCCGTGGTGCTGCCCGTGG
GCGCCAATGCCAGCTCGCGGAGGCTCGTCGCCCATGTGGTGGGACGTCCAGGGTTGGAGCCCGTGGCGCTCCGGCGCATG
CTGGCTCGTGAGACGCCGGCGTACATGCTCCCCAGCCGGATTCACGTGCTGGATGCGTTTCCCCGGACGCCCAACGGAAA
GATTGACCTTGCACGCCTGCAAGTGCTCGAGCCCCGAAGGTCCGCCTCCCATGGCGAGCCACGAACACCCGAGGAGGAAC
ACCTGTGCGCGCTGCTCGAGGAAATCCTCGGGGTCAGCGTGGAGGCCGACCAGGGCTTCTTCGAGGTGGGCGGCGACAGC
CTGAGCGCGGCCCGGTTCATCGTCGAGGCACGCGCGCGGCACCGCTACATGCTGCCGATACAGGCCTTGCTGCAAGGGGC
CACGCTTCGAGCGCTCGCGCGAGCGCTGGTCACTGCGCCACAGGCACCCGCTCCGGAGGTGGCACGACTGCCAGAGGCGC
CTGGATATCCCGCCTCGGACGCGCAGCGCCGGCTGTGGCTGGTGCACGAGGTAAATGGTGGCTCGGCGGCCTACAACCTC
GTCCATGCGTGGTGGGTGGACGGAGAACTGGACGTCGCCCTGCTCCGCCGCGCCCTCGATCGGCTCATCCAGCGGCACGA
AGCCCTGAGGACACGCTTCGACCTCAGGGACGGCGTACTGGTGCAATGCATCGAGCAGGAAGCTCGCGTCGACTGGCTGG
AGCCCCAGGGGACGCCGGCCCCGGAGCTGTTCCTGGAGGCAGAGGCCGCCCACGCATTCTCTCTTCGCACAGGTCCGTTG
GTCCGGGCCGCGGTCCTGGCCGTGGCCCCCCAAAGATGGCTCTTCACCCTCAACATCCACCACATCGTCTGTGATGGCTG
GTCGATGGGTGTCATCACCCGGGAACTGGAGCACACGTATCGGGCACTGCGCGGCGGCGCCTCGCCTCCCGTCGTCCCGC
TCCCCCTCCAGCTCCGCGACTTCACCGCGTGGCAGCGGCAACGCGTGGAGGGCCCCGCTGGACGCGATGCCGCGCACTAC
TGGCGCGCCCGACTGGCGGAGGAAGGGGGCTCGCCCCCGCTGGACCTGCCGCTGGACCGGCCCCGGCCCGCGCGCCCCAC
GCAGGCAGGGCGCGTACACCAGGTGCGCGTGCCCCCCGAGCAACTGCGCGCCCTGGAGAACCTGGCCCAGCGCACCCGGA
CGACCTTGTTCGTGGCGCTCACCGCCCTGGTCAAGCTGCTGCTGTACCGGGAGACACGGCAGAGTGACATCTCCCTCGGG
GCCCCGCTGGCCGAGCGAGACCACCTGGACCTGGCGGAGCAGGTCGGGTTCTACGTCAACACCATCGTCCTGAGGACCCG
GCTCGACGGACGGGAATCCTTCGTTCAACTCCTCGAGCGCGTCCGGCAGGGCAGCACCATGGCGCAGCACCATGGCCTCC
TCCCCTTCGACCGGGTGGTCGAGGCGTCCGGGTTGCCTCGTGAGCCATCCCGCTCCCCCCTCTTTGACGTGATGATTGCG
CTCCAGCAGGAGGAGCATCGCGCCCTGCGCCTGGCGGGGACCACCTGCACCCGCGTGGAGATTCCCCACCACACGAGCAA
GTTCGACCTCAGCTTCGACTTCGTCCGGACCGGCGAAGCGCTGGTCATGGAGCTCGAATACGCCACGGATCTATTCGACG
CGGACCGCATCGAGCGACTCGCGCAGCGCCAGCTCCAGCTCCTGGGCGAGGTCCTCTGCAAACCGGATGCACCCCTGGAC
GCGCTGCAGCCCCTGCCTCCGGCGGAGCAGACCTTCATCCTCGAGATGTTCGGGGGGCGCCGCCTTCCCACGCCCGCTCC
CGACGGCCTGCTCGCCGGCTTCCGTCACGCCGTCGCGAAGGACGGAGGCCGCCCCGCGTTGCTCTGCGGCTCCAGGCGGC
TCACCTACACGCAGGTCGCGGACGAGGCGCACAGGCTCGCGGAGGAGCTCGGCGCCCGGCTCGCGAAGGCCGGCTGGCCC
GAGCGGCCCGTCGCGGTGATGCTGGAGCGCTCGGAAGCCTTCTTCGTCGTTGTCCTGGGCATCCTCGAGCTGGGCCAGGC
ATACCTTCCCATCGACCCCGGACTCCCGCCGGACCGAATCCGACTGCTCCTGCGTGACAGCAGCTGCGCGGTGTTCGTCA
CGCGAGCCTCGCTGCTCGCCGGCCCTTGCCCCGAAGGCATCGAGCTCGTCGACCTGGATACGCAGGGCCCCGTCGCGCCA
CCCGGGCGGCGAGAGGAGCGGCCTCCGCGAGGAGCCAGTCCGCTGGCCTATTGCATCTACACCTCGGGCTCCACGGGGCA
GCCCAAGGCCGTCGGTGTGACGCGGGACAACTTGAGCAACGCCGTGGCGGTGTGGCGCCAGGACTACGGGCTCGTTCGCC
CTGTCGTCCTGCAGTTGGCGAACTTCGCCTTCGACGTGTCGGTGGGGGACCTCGGACGCTCCCTGCTCATCGGCGGCACG
CTGGTCATCGCCACGGACGAGGAACGCGTGAGTCCCGAGCGCATCCTGTCGCTCATCGAACGCCACCGGGTGACGTTCCT
CGAGACAACCCCCGTGGTGGCGAATGCCATCCGGGTGCACCTCGAAGTCATGGACCAGCCGCCCCCTCCGCTGGACCTTC
TGGTGGTGGGCTCGGACACCTGGCGGATGGGAGACCTGCGCGCCCTGCGCCGTCGCCTCCACGCCAGCACGCGGCTGGTC
AACAGCTACGGGACGACAGAGACCACGATTGACAGCAGCTTCTTCGAGCTCGACGCCACGGCTTCGGGAAGCCCCATGAG
CGACGACGCCATGGCCCCCATCGGACGCCCGATGACGCACGTGGAGTTCCTCGTCGTCGACCCCGCGGGCCGGATGCTGG
GCATCGGGACACCGGGCGAGCTGTGCATCGCGGGGCCGTCGGTGTCCCTGGGGTACCTCGGCCGGCCGGACCTCACGGCG
GAACGCTTCGTCCCGCACCCGCGCCACCCAGGTGAGCGCATGTACAGGACAGGAGACCTGGGCGTCCTCCGGGGAGACGG
CAACGTCGCCCTGCTCGGACGCGCGGACCAGCAAGTCAAGGTCCGGGGCTACCGGGTCGAGCTGGGAGAGATAGAGCGCG
TGCTCCTCCAGCACCCGGACGTCCACGCGGGGGTCGTCCTGTTGCTGGGCAGCGGAGCCCAAGCCACCCTGGTGGGCTGC
GTCATCGGCGTGCCCGAAGAGGCGCTGGCGGGACTCGAGTCCTGGCTGGCGGCACGGTTGCCACACTACATGGTGCCCAC
GCAGTGGCTGGCGCAGGAGTCCTTCCCGGCCAGCGCCAATGGCAAGGTGGACCGGCGCGCGCTCCAGGCGGCTGCTGCGC
ATGCGCGGCGCGCGCGTCAGGCGCAGGTGATGCCGAGCACTCCGCTTCAGCAGGTCCTGCTCGAAGGCTGGCGCGAAGTC
CTGCCGCAAGTGCGGAGCCTGAGTGTCACGGACTCCTTCTTCAGCCTGGGGGGCGACTCCATCCAGGCCATCCAGCTCGT
GCTGGCGCTCCGCCGCCGCGGACTGGAGCTCAGCGCCGCGGAGCTGTTCCGCCACCCCACCATCGAGAGCTGCGGCGCCT
ACCTCGAGACCAGGCAAGGCCAGCCGGCGCGGGCGCTCGACCTGGCGGCGTCCGAGGTCGACGCGGTGGTGCGCCAGCGG
CTGCTGCGCCCGGGAGACCAGGAACTCTACCCGGCCACGGCGGTGCAGGTCCTCATGCTCGAGGCCCATGCGCACCACCG
CCCCGTGGACGCCGTCTACCTCGGTTACACCGTCTGGGAGTTCGAAGACGAACGGCTGGAGCTGGCCATCCTGCGCGAGG
CCCTGCTGCGCCAGCTCTCGCGCCACGGCGCGCTCCGCACGACCTTCACGCGCGACACCGATGGCCGGTGGTACCAGCGG
GTCCGGCCCGTAGCGGCGGTGGAGCTCGCGGAGCTCGACCTGTCGGACCGGCCTCGCTCCGCCCAGGACGCCGACCTCGA
CGAGCGCGCCCAGAGGGAGCTGGCGCGGGACATTCTCGCCGACGTCGATGCTCCCGCCTGCCGGATTCTCCTGGTGAGAC
GCGGACCAGGGGCTTGCGCGCTGCTCATGACGACGCACCACGCCGTGGATGACGGCTGGGGATTGACGGCCTTCGAGAAT
GCCCTGCTCCAGGACTACGCGGCGCTGCGCCGCGGCGTGGCGCTTCCCGTCCCGCCACCGCTTCCAACGGGACGCCAGCT
CGTCGCGCTGGAGGCAGAGCGGCTGCGCGACGAGCGCGCACGCGCGTATTGGGCAGACATCCTCCAGCGGCTGCCACCTC
CGCCCTACGCCACCCGCGCTCCCGTCCCTCCGTCCCGCTCCCGCTTCGAGGGCTTCTCGCTCACCGTCCCCCCAGCCACG
CAAGCGCGGGCGGCGCAGAGGGCGCAAGACGCGGGAAGCTCCCTCAAGGCGCTCTACCTGTCCGCGCTGCTCCACGCACT
CGCCGAGGAGGCGCGCACCGACACGTCGAGCGCCTGGGTGGTGATGAACGGACGCTCGGAACGCCTCGATGCCGCGTTGG
ACGCGGTAGGCCTCTTCTGGAGCCTCGTCCCCGTCATCGGAAGCAACGTGGGCACTCCGCGGACACGCCTCAAGGCGATG
GATGAACAGCTCCGTCAAGCGGAGCTGCACGGCGCATGGTTCTTCCCGGACCTCTTTGGGGACTGCCTGGGCGCGGGCTT
CCCCGTCTGCTTCAACTTCACGCACTTCTGGAACGAACAGCCCTCCCCTGAGGGGGTCCGCGTGGCCGCGCGGCACATGC
ACAACGTGTGGCACTTCCCTTTGACTGTCACGCTCTCGCTGAACTCCACATCCGGCACCGCGACGCTCCACGTCATGCAT
GACGCCACGTCGCTGTCCCGGCCCCATATCGACGCGCTCCTGGAGCGGGTGCTCCAGGCTCTCGCCGACCGGGAGTCCTC
GCCATGA

Upstream 100 bases:

>100_bases
TGATGGACGACTGCATCGCCAACAAGCTCCTGAGCGCCAATGAACGGGCGATGACGGATGCCCAGAAGTTCTCGGAGGCG
CTGGGCATCGACAACATCCA

Downstream 100 bases:

>100_bases
AGGTGATACGCGCCCTCCTCTCCTCGGATGCCGTCACGGCCCACATCCGGCAGGCCTATTCCCTGGCGGAACCCATCCAG
GCGCAGCTCCTGGCCACCGG

Product: non-ribosomal peptide synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Gramicidin S synthase II; ATP-dependent proline adenylase; ProA; Proline activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 2108; Mature: 2107

Protein sequence:

>2108_residues
MGPRRRVALSFVRAMPHSIASTVPEAGPPLDVVELFVRQASRTPHRVAISTGTVQLTYQELERRARSLHARLGLLGAVPQ
TPVGVFAERTPEALVAALAVLMAGCVYVPIDPAYPTERIDYMLQDSGAPLVLGPHTHRDTRNLAARFLALDEENAPPTSL
PEARQAPPHPESLAYIIYTSGSTGLPKGVMVEHGGLLNLVLDHVAAFDVVPEDRVLLVTSPSFDASMFQLFITWATGATL
LLPPEHVVADPDAMVGWLNEHRATLLSMPPAYLHALGRRPIPSVRLVNTGGDAPIEEDALHYARTCRYVSTYGPTETTIC
SAYHEVHADASFPEGIPLGRPVRNASMFVLDEAGGICPPGQLGELCIAGQGVSRGYHARPELTAQKFVPHPYHPGARAYR
TGDLGYQRSDGVFFFRGRVDRQVKIRGYRVEPEEVESRLQALEGVERAVVLPVGANASSRRLVAHVVGRPGLEPVALRRM
LARETPAYMLPSRIHVLDAFPRTPNGKIDLARLQVLEPRRSASHGEPRTPEEEHLCALLEEILGVSVEADQGFFEVGGDS
LSAARFIVEARARHRYMLPIQALLQGATLRALARALVTAPQAPAPEVARLPEAPGYPASDAQRRLWLVHEVNGGSAAYNL
VHAWWVDGELDVALLRRALDRLIQRHEALRTRFDLRDGVLVQCIEQEARVDWLEPQGTPAPELFLEAEAAHAFSLRTGPL
VRAAVLAVAPQRWLFTLNIHHIVCDGWSMGVITRELEHTYRALRGGASPPVVPLPLQLRDFTAWQRQRVEGPAGRDAAHY
WRARLAEEGGSPPLDLPLDRPRPARPTQAGRVHQVRVPPEQLRALENLAQRTRTTLFVALTALVKLLLYRETRQSDISLG
APLAERDHLDLAEQVGFYVNTIVLRTRLDGRESFVQLLERVRQGSTMAQHHGLLPFDRVVEASGLPREPSRSPLFDVMIA
LQQEEHRALRLAGTTCTRVEIPHHTSKFDLSFDFVRTGEALVMELEYATDLFDADRIERLAQRQLQLLGEVLCKPDAPLD
ALQPLPPAEQTFILEMFGGRRLPTPAPDGLLAGFRHAVAKDGGRPALLCGSRRLTYTQVADEAHRLAEELGARLAKAGWP
ERPVAVMLERSEAFFVVVLGILELGQAYLPIDPGLPPDRIRLLLRDSSCAVFVTRASLLAGPCPEGIELVDLDTQGPVAP
PGRREERPPRGASPLAYCIYTSGSTGQPKAVGVTRDNLSNAVAVWRQDYGLVRPVVLQLANFAFDVSVGDLGRSLLIGGT
LVIATDEERVSPERILSLIERHRVTFLETTPVVANAIRVHLEVMDQPPPPLDLLVVGSDTWRMGDLRALRRRLHASTRLV
NSYGTTETTIDSSFFELDATASGSPMSDDAMAPIGRPMTHVEFLVVDPAGRMLGIGTPGELCIAGPSVSLGYLGRPDLTA
ERFVPHPRHPGERMYRTGDLGVLRGDGNVALLGRADQQVKVRGYRVELGEIERVLLQHPDVHAGVVLLLGSGAQATLVGC
VIGVPEEALAGLESWLAARLPHYMVPTQWLAQESFPASANGKVDRRALQAAAAHARRARQAQVMPSTPLQQVLLEGWREV
LPQVRSLSVTDSFFSLGGDSIQAIQLVLALRRRGLELSAAELFRHPTIESCGAYLETRQGQPARALDLAASEVDAVVRQR
LLRPGDQELYPATAVQVLMLEAHAHHRPVDAVYLGYTVWEFEDERLELAILREALLRQLSRHGALRTTFTRDTDGRWYQR
VRPVAAVELAELDLSDRPRSAQDADLDERAQRELARDILADVDAPACRILLVRRGPGACALLMTTHHAVDDGWGLTAFEN
ALLQDYAALRRGVALPVPPPLPTGRQLVALEAERLRDERARAYWADILQRLPPPPYATRAPVPPSRSRFEGFSLTVPPAT
QARAAQRAQDAGSSLKALYLSALLHALAEEARTDTSSAWVVMNGRSERLDAALDAVGLFWSLVPVIGSNVGTPRTRLKAM
DEQLRQAELHGAWFFPDLFGDCLGAGFPVCFNFTHFWNEQPSPEGVRVAARHMHNVWHFPLTVTLSLNSTSGTATLHVMH
DATSLSRPHIDALLERVLQALADRESSP

Sequences:

>Translated_2108_residues
MGPRRRVALSFVRAMPHSIASTVPEAGPPLDVVELFVRQASRTPHRVAISTGTVQLTYQELERRARSLHARLGLLGAVPQ
TPVGVFAERTPEALVAALAVLMAGCVYVPIDPAYPTERIDYMLQDSGAPLVLGPHTHRDTRNLAARFLALDEENAPPTSL
PEARQAPPHPESLAYIIYTSGSTGLPKGVMVEHGGLLNLVLDHVAAFDVVPEDRVLLVTSPSFDASMFQLFITWATGATL
LLPPEHVVADPDAMVGWLNEHRATLLSMPPAYLHALGRRPIPSVRLVNTGGDAPIEEDALHYARTCRYVSTYGPTETTIC
SAYHEVHADASFPEGIPLGRPVRNASMFVLDEAGGICPPGQLGELCIAGQGVSRGYHARPELTAQKFVPHPYHPGARAYR
TGDLGYQRSDGVFFFRGRVDRQVKIRGYRVEPEEVESRLQALEGVERAVVLPVGANASSRRLVAHVVGRPGLEPVALRRM
LARETPAYMLPSRIHVLDAFPRTPNGKIDLARLQVLEPRRSASHGEPRTPEEEHLCALLEEILGVSVEADQGFFEVGGDS
LSAARFIVEARARHRYMLPIQALLQGATLRALARALVTAPQAPAPEVARLPEAPGYPASDAQRRLWLVHEVNGGSAAYNL
VHAWWVDGELDVALLRRALDRLIQRHEALRTRFDLRDGVLVQCIEQEARVDWLEPQGTPAPELFLEAEAAHAFSLRTGPL
VRAAVLAVAPQRWLFTLNIHHIVCDGWSMGVITRELEHTYRALRGGASPPVVPLPLQLRDFTAWQRQRVEGPAGRDAAHY
WRARLAEEGGSPPLDLPLDRPRPARPTQAGRVHQVRVPPEQLRALENLAQRTRTTLFVALTALVKLLLYRETRQSDISLG
APLAERDHLDLAEQVGFYVNTIVLRTRLDGRESFVQLLERVRQGSTMAQHHGLLPFDRVVEASGLPREPSRSPLFDVMIA
LQQEEHRALRLAGTTCTRVEIPHHTSKFDLSFDFVRTGEALVMELEYATDLFDADRIERLAQRQLQLLGEVLCKPDAPLD
ALQPLPPAEQTFILEMFGGRRLPTPAPDGLLAGFRHAVAKDGGRPALLCGSRRLTYTQVADEAHRLAEELGARLAKAGWP
ERPVAVMLERSEAFFVVVLGILELGQAYLPIDPGLPPDRIRLLLRDSSCAVFVTRASLLAGPCPEGIELVDLDTQGPVAP
PGRREERPPRGASPLAYCIYTSGSTGQPKAVGVTRDNLSNAVAVWRQDYGLVRPVVLQLANFAFDVSVGDLGRSLLIGGT
LVIATDEERVSPERILSLIERHRVTFLETTPVVANAIRVHLEVMDQPPPPLDLLVVGSDTWRMGDLRALRRRLHASTRLV
NSYGTTETTIDSSFFELDATASGSPMSDDAMAPIGRPMTHVEFLVVDPAGRMLGIGTPGELCIAGPSVSLGYLGRPDLTA
ERFVPHPRHPGERMYRTGDLGVLRGDGNVALLGRADQQVKVRGYRVELGEIERVLLQHPDVHAGVVLLLGSGAQATLVGC
VIGVPEEALAGLESWLAARLPHYMVPTQWLAQESFPASANGKVDRRALQAAAAHARRARQAQVMPSTPLQQVLLEGWREV
LPQVRSLSVTDSFFSLGGDSIQAIQLVLALRRRGLELSAAELFRHPTIESCGAYLETRQGQPARALDLAASEVDAVVRQR
LLRPGDQELYPATAVQVLMLEAHAHHRPVDAVYLGYTVWEFEDERLELAILREALLRQLSRHGALRTTFTRDTDGRWYQR
VRPVAAVELAELDLSDRPRSAQDADLDERAQRELARDILADVDAPACRILLVRRGPGACALLMTTHHAVDDGWGLTAFEN
ALLQDYAALRRGVALPVPPPLPTGRQLVALEAERLRDERARAYWADILQRLPPPPYATRAPVPPSRSRFEGFSLTVPPAT
QARAAQRAQDAGSSLKALYLSALLHALAEEARTDTSSAWVVMNGRSERLDAALDAVGLFWSLVPVIGSNVGTPRTRLKAM
DEQLRQAELHGAWFFPDLFGDCLGAGFPVCFNFTHFWNEQPSPEGVRVAARHMHNVWHFPLTVTLSLNSTSGTATLHVMH
DATSLSRPHIDALLERVLQALADRESSP
>Mature_2107_residues
GPRRRVALSFVRAMPHSIASTVPEAGPPLDVVELFVRQASRTPHRVAISTGTVQLTYQELERRARSLHARLGLLGAVPQT
PVGVFAERTPEALVAALAVLMAGCVYVPIDPAYPTERIDYMLQDSGAPLVLGPHTHRDTRNLAARFLALDEENAPPTSLP
EARQAPPHPESLAYIIYTSGSTGLPKGVMVEHGGLLNLVLDHVAAFDVVPEDRVLLVTSPSFDASMFQLFITWATGATLL
LPPEHVVADPDAMVGWLNEHRATLLSMPPAYLHALGRRPIPSVRLVNTGGDAPIEEDALHYARTCRYVSTYGPTETTICS
AYHEVHADASFPEGIPLGRPVRNASMFVLDEAGGICPPGQLGELCIAGQGVSRGYHARPELTAQKFVPHPYHPGARAYRT
GDLGYQRSDGVFFFRGRVDRQVKIRGYRVEPEEVESRLQALEGVERAVVLPVGANASSRRLVAHVVGRPGLEPVALRRML
ARETPAYMLPSRIHVLDAFPRTPNGKIDLARLQVLEPRRSASHGEPRTPEEEHLCALLEEILGVSVEADQGFFEVGGDSL
SAARFIVEARARHRYMLPIQALLQGATLRALARALVTAPQAPAPEVARLPEAPGYPASDAQRRLWLVHEVNGGSAAYNLV
HAWWVDGELDVALLRRALDRLIQRHEALRTRFDLRDGVLVQCIEQEARVDWLEPQGTPAPELFLEAEAAHAFSLRTGPLV
RAAVLAVAPQRWLFTLNIHHIVCDGWSMGVITRELEHTYRALRGGASPPVVPLPLQLRDFTAWQRQRVEGPAGRDAAHYW
RARLAEEGGSPPLDLPLDRPRPARPTQAGRVHQVRVPPEQLRALENLAQRTRTTLFVALTALVKLLLYRETRQSDISLGA
PLAERDHLDLAEQVGFYVNTIVLRTRLDGRESFVQLLERVRQGSTMAQHHGLLPFDRVVEASGLPREPSRSPLFDVMIAL
QQEEHRALRLAGTTCTRVEIPHHTSKFDLSFDFVRTGEALVMELEYATDLFDADRIERLAQRQLQLLGEVLCKPDAPLDA
LQPLPPAEQTFILEMFGGRRLPTPAPDGLLAGFRHAVAKDGGRPALLCGSRRLTYTQVADEAHRLAEELGARLAKAGWPE
RPVAVMLERSEAFFVVVLGILELGQAYLPIDPGLPPDRIRLLLRDSSCAVFVTRASLLAGPCPEGIELVDLDTQGPVAPP
GRREERPPRGASPLAYCIYTSGSTGQPKAVGVTRDNLSNAVAVWRQDYGLVRPVVLQLANFAFDVSVGDLGRSLLIGGTL
VIATDEERVSPERILSLIERHRVTFLETTPVVANAIRVHLEVMDQPPPPLDLLVVGSDTWRMGDLRALRRRLHASTRLVN
SYGTTETTIDSSFFELDATASGSPMSDDAMAPIGRPMTHVEFLVVDPAGRMLGIGTPGELCIAGPSVSLGYLGRPDLTAE
RFVPHPRHPGERMYRTGDLGVLRGDGNVALLGRADQQVKVRGYRVELGEIERVLLQHPDVHAGVVLLLGSGAQATLVGCV
IGVPEEALAGLESWLAARLPHYMVPTQWLAQESFPASANGKVDRRALQAAAAHARRARQAQVMPSTPLQQVLLEGWREVL
PQVRSLSVTDSFFSLGGDSIQAIQLVLALRRRGLELSAAELFRHPTIESCGAYLETRQGQPARALDLAASEVDAVVRQRL
LRPGDQELYPATAVQVLMLEAHAHHRPVDAVYLGYTVWEFEDERLELAILREALLRQLSRHGALRTTFTRDTDGRWYQRV
RPVAAVELAELDLSDRPRSAQDADLDERAQRELARDILADVDAPACRILLVRRGPGACALLMTTHHAVDDGWGLTAFENA
LLQDYAALRRGVALPVPPPLPTGRQLVALEAERLRDERARAYWADILQRLPPPPYATRAPVPPSRSRFEGFSLTVPPATQ
ARAAQRAQDAGSSLKALYLSALLHALAEEARTDTSSAWVVMNGRSERLDAALDAVGLFWSLVPVIGSNVGTPRTRLKAMD
EQLRQAELHGAWFFPDLFGDCLGAGFPVCFNFTHFWNEQPSPEGVRVAARHMHNVWHFPLTVTLSLNSTSGTATLHVMHD
ATSLSRPHIDALLERVLQALADRESSP

Specific function: This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Val, Orn and Leu. Activation sites for these AA consist of individual domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=424, Percent_Identity=25.7075471698113, Blast_Score=114, Evalue=1e-24,
Organism=Homo sapiens, GI38505220, Length=511, Percent_Identity=23.4833659491194, Blast_Score=92, Evalue=5e-18,
Organism=Homo sapiens, GI42544132, Length=458, Percent_Identity=23.7991266375546, Blast_Score=87, Evalue=2e-16,
Organism=Homo sapiens, GI156151445, Length=379, Percent_Identity=23.7467018469657, Blast_Score=86, Evalue=3e-16,
Organism=Homo sapiens, GI122937307, Length=361, Percent_Identity=26.0387811634349, Blast_Score=77, Evalue=2e-13,
Organism=Homo sapiens, GI115511026, Length=474, Percent_Identity=23.2067510548523, Blast_Score=70, Evalue=3e-11,
Organism=Escherichia coli, GI1786801, Length=1073, Percent_Identity=27.3066169617894, Blast_Score=241, Evalue=5e-64,
Organism=Escherichia coli, GI145693145, Length=460, Percent_Identity=26.5217391304348, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1788107, Length=539, Percent_Identity=23.5621521335807, Blast_Score=97, Evalue=9e-21,
Organism=Escherichia coli, GI1790505, Length=524, Percent_Identity=25.5725190839695, Blast_Score=88, Evalue=5e-18,
Organism=Escherichia coli, GI1786810, Length=561, Percent_Identity=24.2424242424242, Blast_Score=81, Evalue=6e-16,
Organism=Escherichia coli, GI221142682, Length=505, Percent_Identity=23.7623762376238, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17550940, Length=1160, Percent_Identity=21.2931034482759, Blast_Score=139, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17556356, Length=589, Percent_Identity=25.2971137521222, Blast_Score=130, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17531443, Length=454, Percent_Identity=25.1101321585903, Blast_Score=97, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17559526, Length=366, Percent_Identity=23.4972677595628, Blast_Score=93, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560308, Length=527, Percent_Identity=23.9089184060721, Blast_Score=91, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32564420, Length=433, Percent_Identity=23.3256351039261, Blast_Score=87, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI32564422, Length=433, Percent_Identity=23.3256351039261, Blast_Score=87, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560140, Length=498, Percent_Identity=23.2931726907631, Blast_Score=79, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538037, Length=542, Percent_Identity=23.2472324723247, Blast_Score=77, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17558820, Length=448, Percent_Identity=22.7678571428571, Blast_Score=72, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994703, Length=375, Percent_Identity=22.9333333333333, Blast_Score=71, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994694, Length=375, Percent_Identity=22.9333333333333, Blast_Score=71, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71994690, Length=375, Percent_Identity=22.9333333333333, Blast_Score=71, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=906, Percent_Identity=24.0618101545254, Blast_Score=184, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6319699, Length=515, Percent_Identity=22.1359223300971, Blast_Score=96, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6323182, Length=540, Percent_Identity=24.0740740740741, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24648676, Length=589, Percent_Identity=27.3344651952462, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24581924, Length=518, Percent_Identity=23.7451737451737, Blast_Score=97, Evalue=9e-20,
Organism=Drosophila melanogaster, GI21355181, Length=475, Percent_Identity=24, Blast_Score=92, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24648260, Length=534, Percent_Identity=23.0337078651685, Blast_Score=85, Evalue=7e-16,
Organism=Drosophila melanogaster, GI18859661, Length=469, Percent_Identity=24.3070362473348, Blast_Score=84, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356441, Length=534, Percent_Identity=22.4719101123595, Blast_Score=82, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24656500, Length=525, Percent_Identity=24.1904761904762, Blast_Score=81, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24648257, Length=419, Percent_Identity=26.7303102625298, Blast_Score=79, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21358303, Length=496, Percent_Identity=21.3709677419355, Blast_Score=77, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 231576; Mature: 231445

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPRRRVALSFVRAMPHSIASTVPEAGPPLDVVELFVRQASRTPHRVAISTGTVQLTYQE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCEEEEEHHH
LERRARSLHARLGLLGAVPQTPVGVFAERTPEALVAALAVLMAGCVYVPIDPAYPTERID
HHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHCEEEEECCCCCCHHHHH
YMLQDSGAPLVLGPHTHRDTRNLAARFLALDEENAPPTSLPEARQAPPHPESLAYIIYTS
HHEECCCCCEEECCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
GSTGLPKGVMVEHGGLLNLVLDHVAAFDVVPEDRVLLVTSPSFDASMFQLFITWATGATL
CCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEE
LLPPEHVVADPDAMVGWLNEHRATLLSMPPAYLHALGRRPIPSVRLVNTGGDAPIEEDAL
EECCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCCCHHHHH
HYARTCRYVSTYGPTETTICSAYHEVHADASFPEGIPLGRPVRNASMFVLDEAGGICPPG
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
QLGELCIAGQGVSRGYHARPELTAQKFVPHPYHPGARAYRTGDLGYQRSDGVFFFRGRVD
CCCCEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEECCCCCCCCCCCEEEEECCCC
RQVKIRGYRVEPEEVESRLQALEGVERAVVLPVGANASSRRLVAHVVGRPGLEPVALRRM
CEEEEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCCCCCCHHHHHHH
LARETPAYMLPSRIHVLDAFPRTPNGKIDLARLQVLEPRRSASHGEPRTPEEEHLCALLE
HHHCCCCHHCCCCEEEEECCCCCCCCCEEEEHHEEECCHHCCCCCCCCCCCHHHHHHHHH
EILGVSVEADQGFFEVGGDSLSAARFIVEARARHRYMLPIQALLQGATLRALARALVTAP
HHHCCEEECCCCCEEECCCCHHHHHHHHHHHHCCEEECCHHHHHCCHHHHHHHHHHHCCC
QAPAPEVARLPEAPGYPASDAQRRLWLVHEVNGGSAAYNLVHAWWVDGELDVALLRRALD
CCCCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHEEEEEEEEECCCCCHHHHHHHHH
RLIQRHEALRTRFDLRDGVLVQCIEQEARVDWLEPQGTPAPELFLEAEAAHAFSLRTGPL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECCCCCCCHHHEEEHHHHHEEECCCCHH
VRAAVLAVAPQRWLFTLNIHHIVCDGWSMGVITRELEHTYRALRGGASPPVVPLPLQLRD
HHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHH
FTAWQRQRVEGPAGRDAAHYWRARLAEEGGSPPLDLPLDRPRPARPTQAGRVHQVRVPPE
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHH
QLRALENLAQRTRTTLFVALTALVKLLLYRETRQSDISLGAPLAERDHLDLAEQVGFYVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
TIVLRTRLDGRESFVQLLERVRQGSTMAQHHGLLPFDRVVEASGLPREPSRSPLFDVMIA
HEEEEECCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHH
LQQEEHRALRLAGTTCTRVEIPHHTSKFDLSFDFVRTGEALVMELEYATDLFDADRIERL
HHHHHCCEEEEECCEEEEEECCCCCCEECEEEEEEECCCEEEEEEHHHHHHCCHHHHHHH
AQRQLQLLGEVLCKPDAPLDALQPLPPAEQTFILEMFGGRRLPTPAPDGLLAGFRHAVAK
HHHHHHHHHHHHCCCCCCHHHHCCCCCCHHEEEEEHHCCCCCCCCCCCHHHHHHHHHHHC
DGGRPALLCGSRRLTYTQVADEAHRLAEELGARLAKAGWPERPVAVMLERSEAFFVVVLG
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHH
ILELGQAYLPIDPGLPPDRIRLLLRDSSCAVFVTRASLLAGPCPEGIELVDLDTQGPVAP
HHHHCCEEECCCCCCCHHHEEEEEECCCCEEEEEEHHHHCCCCCCCCEEEEECCCCCCCC
PGRREERPPRGASPLAYCIYTSGSTGQPKAVGVTRDNLSNAVAVWRQDYGLVRPVVLQLA
CCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHH
NFAFDVSVGDLGRSLLIGGTLVIATDEERVSPERILSLIERHRVTFLETTPVVANAIRVH
HHHEEEEHHHCCCEEEECCEEEEECCHHHCCHHHHHHHHHHHCEEEEECCHHHHHHHHEE
LEVMDQPPPPLDLLVVGSDTWRMGDLRALRRRLHASTRLVNSYGTTETTIDSSFFELDAT
EEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEECC
ASGSPMSDDAMAPIGRPMTHVEFLVVDPAGRMLGIGTPGELCIAGPSVSLGYLGRPDLTA
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCEEEECCCCCCCCCCCCCCCH
ERFVPHPRHPGERMYRTGDLGVLRGDGNVALLGRADQQVKVRGYRVELGEIERVLLQHPD
HHCCCCCCCCHHHHEECCCEEEEECCCCEEEEECCCCEEEEEEEEEEHHHHHHHHHCCCC
VHAGVVLLLGSGAQATLVGCVIGVPEEALAGLESWLAARLPHYMVPTQWLAQESFPASAN
CCCCEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCC
GKVDRRALQAAAAHARRARQAQVMPSTPLQQVLLEGWREVLPQVRSLSVTDSFFSLGGDS
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCH
IQAIQLVLALRRRGLELSAAELFRHPTIESCGAYLETRQGQPARALDLAASEVDAVVRQR
HHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LLRPGDQELYPATAVQVLMLEAHAHHRPVDAVYLGYTVWEFEDERLELAILREALLRQLS
HCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHH
RHGALRTTFTRDTDGRWYQRVRPVAAVELAELDLSDRPRSAQDADLDERAQRELARDILA
HCCCEEEEEECCCCCHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
DVDAPACRILLVRRGPGACALLMTTHHAVDDGWGLTAFENALLQDYAALRRGVALPVPPP
CCCCCCEEEEEEECCCCCEEEEEEECHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
LPTGRQLVALEAERLRDERARAYWADILQRLPPPPYATRAPVPPSRSRFEGFSLTVPPAT
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCH
QARAAQRAQDAGSSLKALYLSALLHALAEEARTDTSSAWVVMNGRSERLDAALDAVGLFW
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHH
SLVPVIGSNVGTPRTRLKAMDEQLRQAELHGAWFFPDLFGDCLGAGFPVCFNFTHFWNEQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHCCCCHHEECHHHHHCCC
PSPEGVRVAARHMHNVWHFPLTVTLSLNSTSGTATLHVMHDATSLSRPHIDALLERVLQA
CCCCHHHHHHHHHHHEEEEEEEEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHH
LADRESSP
HHCCCCCC
>Mature Secondary Structure 
GPRRRVALSFVRAMPHSIASTVPEAGPPLDVVELFVRQASRTPHRVAISTGTVQLTYQE
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCEEEEEHHH
LERRARSLHARLGLLGAVPQTPVGVFAERTPEALVAALAVLMAGCVYVPIDPAYPTERID
HHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHCEEEEECCCCCCHHHHH
YMLQDSGAPLVLGPHTHRDTRNLAARFLALDEENAPPTSLPEARQAPPHPESLAYIIYTS
HHEECCCCCEEECCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
GSTGLPKGVMVEHGGLLNLVLDHVAAFDVVPEDRVLLVTSPSFDASMFQLFITWATGATL
CCCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEE
LLPPEHVVADPDAMVGWLNEHRATLLSMPPAYLHALGRRPIPSVRLVNTGGDAPIEEDAL
EECCHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCCCHHHHH
HYARTCRYVSTYGPTETTICSAYHEVHADASFPEGIPLGRPVRNASMFVLDEAGGICPPG
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
QLGELCIAGQGVSRGYHARPELTAQKFVPHPYHPGARAYRTGDLGYQRSDGVFFFRGRVD
CCCCEEEECCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEECCCCCCCCCCCEEEEECCCC
RQVKIRGYRVEPEEVESRLQALEGVERAVVLPVGANASSRRLVAHVVGRPGLEPVALRRM
CEEEEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHCCCCCCHHHHHHH
LARETPAYMLPSRIHVLDAFPRTPNGKIDLARLQVLEPRRSASHGEPRTPEEEHLCALLE
HHHCCCCHHCCCCEEEEECCCCCCCCCEEEEHHEEECCHHCCCCCCCCCCCHHHHHHHHH
EILGVSVEADQGFFEVGGDSLSAARFIVEARARHRYMLPIQALLQGATLRALARALVTAP
HHHCCEEECCCCCEEECCCCHHHHHHHHHHHHCCEEECCHHHHHCCHHHHHHHHHHHCCC
QAPAPEVARLPEAPGYPASDAQRRLWLVHEVNGGSAAYNLVHAWWVDGELDVALLRRALD
CCCCCHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHEEEEEEEEECCCCCHHHHHHHHH
RLIQRHEALRTRFDLRDGVLVQCIEQEARVDWLEPQGTPAPELFLEAEAAHAFSLRTGPL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEECCCCCCCHHHEEEHHHHHEEECCCCHH
VRAAVLAVAPQRWLFTLNIHHIVCDGWSMGVITRELEHTYRALRGGASPPVVPLPLQLRD
HHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHH
FTAWQRQRVEGPAGRDAAHYWRARLAEEGGSPPLDLPLDRPRPARPTQAGRVHQVRVPPE
HHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHH
QLRALENLAQRTRTTLFVALTALVKLLLYRETRQSDISLGAPLAERDHLDLAEQVGFYVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
TIVLRTRLDGRESFVQLLERVRQGSTMAQHHGLLPFDRVVEASGLPREPSRSPLFDVMIA
HEEEEECCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHH
LQQEEHRALRLAGTTCTRVEIPHHTSKFDLSFDFVRTGEALVMELEYATDLFDADRIERL
HHHHHCCEEEEECCEEEEEECCCCCCEECEEEEEEECCCEEEEEEHHHHHHCCHHHHHHH
AQRQLQLLGEVLCKPDAPLDALQPLPPAEQTFILEMFGGRRLPTPAPDGLLAGFRHAVAK
HHHHHHHHHHHHCCCCCCHHHHCCCCCCHHEEEEEHHCCCCCCCCCCCHHHHHHHHHHHC
DGGRPALLCGSRRLTYTQVADEAHRLAEELGARLAKAGWPERPVAVMLERSEAFFVVVLG
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHH
ILELGQAYLPIDPGLPPDRIRLLLRDSSCAVFVTRASLLAGPCPEGIELVDLDTQGPVAP
HHHHCCEEECCCCCCCHHHEEEEEECCCCEEEEEEHHHHCCCCCCCCEEEEECCCCCCCC
PGRREERPPRGASPLAYCIYTSGSTGQPKAVGVTRDNLSNAVAVWRQDYGLVRPVVLQLA
CCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHH
NFAFDVSVGDLGRSLLIGGTLVIATDEERVSPERILSLIERHRVTFLETTPVVANAIRVH
HHHEEEEHHHCCCEEEECCEEEEECCHHHCCHHHHHHHHHHHCEEEEECCHHHHHHHHEE
LEVMDQPPPPLDLLVVGSDTWRMGDLRALRRRLHASTRLVNSYGTTETTIDSSFFELDAT
EEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEECC
ASGSPMSDDAMAPIGRPMTHVEFLVVDPAGRMLGIGTPGELCIAGPSVSLGYLGRPDLTA
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCEEEECCCCCCCCCCCCCCCH
ERFVPHPRHPGERMYRTGDLGVLRGDGNVALLGRADQQVKVRGYRVELGEIERVLLQHPD
HHCCCCCCCCHHHHEECCCEEEEECCCCEEEEECCCCEEEEEEEEEEHHHHHHHHHCCCC
VHAGVVLLLGSGAQATLVGCVIGVPEEALAGLESWLAARLPHYMVPTQWLAQESFPASAN
CCCCEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCC
GKVDRRALQAAAAHARRARQAQVMPSTPLQQVLLEGWREVLPQVRSLSVTDSFFSLGGDS
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCH
IQAIQLVLALRRRGLELSAAELFRHPTIESCGAYLETRQGQPARALDLAASEVDAVVRQR
HHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
LLRPGDQELYPATAVQVLMLEAHAHHRPVDAVYLGYTVWEFEDERLELAILREALLRQLS
HCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHH
RHGALRTTFTRDTDGRWYQRVRPVAAVELAELDLSDRPRSAQDADLDERAQRELARDILA
HCCCEEEEEECCCCCHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
DVDAPACRILLVRRGPGACALLMTTHHAVDDGWGLTAFENALLQDYAALRRGVALPVPPP
CCCCCCEEEEEEECCCCCEEEEEEECHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
LPTGRQLVALEAERLRDERARAYWADILQRLPPPPYATRAPVPPSRSRFEGFSLTVPPAT
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCH
QARAAQRAQDAGSSLKALYLSALLHALAEEARTDTSSAWVVMNGRSERLDAALDAVGLFW
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHH
SLVPVIGSNVGTPRTRLKAMDEQLRQAELHGAWFFPDLFGDCLGAGFPVCFNFTHFWNEQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHCCCCHHEECHHHHHCCC
PSPEGVRVAARHMHNVWHFPLTVTLSLNSTSGTATLHVMHDATSLSRPHIDALLERVLQA
CCCCHHHHHHHHHHHEEEEEEEEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHH
LADRESSP
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1560782; 2477357 [H]