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The map label for this gene is galE [C]

Identifier: 108760627

GI number: 108760627

Start: 4085587

End: 4086531

Strand: Direct

Name: galE [C]

Synonym: MXAN_3507

Alternate gene names: 108760627

Gene position: 4085587-4086531 (Clockwise)

Preceding gene: 108757676

Following gene: 108761403

Centisome position: 44.7

GC content: 69.21

Gene sequence:

>945_bases
GTGAAGGTCCTGGTGACAGGTGGCGCGGGCTTCATTGGCTCGCATGTGTGCGATGAGTTCCTGCGCGGTGGTCACGACGT
CATCGCGTTGGATGACCTGTCCGGCGGCAAGCGGGAGAACCTGGACCCGCGTGTGCGCCTGGCGGTCCACGACATCCGCA
GCCGCGAGGCGTCGGAGCTCATCAAGTCCGAGAAGCCCGACGTGCTCTGCCACCTGGCGGCGCAGATGGACGTGCGCCGC
AGCGTGGACGACCCGAGCTTCGACGCGGACGTGAACATCCGCGGCATGCTCAACCTGCTGGAGGCCGCCCGCGTCTCCGG
GGTGAAGAAGGTCATCTTCAGCTCCACCGGCGGCGCCATCTACGGCGAGCAGGACGTGTTCCCCGCGCCGGAGAGTCACC
CCACGCGGCCCATTTCTCCGTACGGTGTCTCCAAGGCGTCCGGTGAGCTGTACCTGGGCTACTACCGGGCGCAGTACGGC
CTGCCCTACGTGGCCCTCCGCTACGCCAACGTCTACGGCCCGCGGCAGAACCCGCACGGTGAGGCGGGTGTGGTGGCCAT
CTTCAGCCAGCGGCTGATCGCCGGTCAGGGCTGCACCATCTTCGGCGAGGGCAAGCAGACCCGCGACTTCGTCTTTGGTC
CGGACGTGGCGCGCGCCAACCGGCTCGCCTTCGAGAACGACTACGTGGGCGCCATCAACATCGGCACGGGCGTGGAGACG
GACATCAACCGCCTCTACGCGCTGCTGGCCGAGGCGGCGGGCTCCAGCGTCTCCGTCGCCCACGCGCCCGGCAAGCCGGG
GGAGCAGATGCGCTCCTGCGTGGACAACGCGCTGGCCAGGAAGGTGCTTGGCTGGGAGCCGAGCGTCGACGTGCGCGAGG
GCCTGCGCCGCACGCTTGAGTACTTCCGTCAGAAGGCCGGCGCGCCCGCTCGCGCGCACGGCTGA

Upstream 100 bases:

>100_bases
TCGGGAGACCATTGCGTGGTTCCGAGAGGTTGCCGGCACGAAGCCCCCGGCATAGTTTGCCGGCGCGAAGATCCTGCATG
GCCTGCAGGCGGGAGGTTGC

Downstream 100 bases:

>100_bases
GCGGCGTCCAGCGCCCCCGCTGGCGGTCGAGGCGGGGGAGGGCGGTACCCCTTCCCACGGACGTACCCGGGCCGGCCCTG
AGGGCCGGGGACCGGGCGTG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKVLVTGGAGFIGSHVCDEFLRGGHDVIALDDLSGGKRENLDPRVRLAVHDIRSREASELIKSEKPDVLCHLAAQMDVRR
SVDDPSFDADVNIRGMLNLLEAARVSGVKKVIFSSTGGAIYGEQDVFPAPESHPTRPISPYGVSKASGELYLGYYRAQYG
LPYVALRYANVYGPRQNPHGEAGVVAIFSQRLIAGQGCTIFGEGKQTRDFVFGPDVARANRLAFENDYVGAINIGTGVET
DINRLYALLAEAAGSSVSVAHAPGKPGEQMRSCVDNALARKVLGWEPSVDVREGLRRTLEYFRQKAGAPARAHG

Sequences:

>Translated_314_residues
MKVLVTGGAGFIGSHVCDEFLRGGHDVIALDDLSGGKRENLDPRVRLAVHDIRSREASELIKSEKPDVLCHLAAQMDVRR
SVDDPSFDADVNIRGMLNLLEAARVSGVKKVIFSSTGGAIYGEQDVFPAPESHPTRPISPYGVSKASGELYLGYYRAQYG
LPYVALRYANVYGPRQNPHGEAGVVAIFSQRLIAGQGCTIFGEGKQTRDFVFGPDVARANRLAFENDYVGAINIGTGVET
DINRLYALLAEAAGSSVSVAHAPGKPGEQMRSCVDNALARKVLGWEPSVDVREGLRRTLEYFRQKAGAPARAHG
>Mature_314_residues
MKVLVTGGAGFIGSHVCDEFLRGGHDVIALDDLSGGKRENLDPRVRLAVHDIRSREASELIKSEKPDVLCHLAAQMDVRR
SVDDPSFDADVNIRGMLNLLEAARVSGVKKVIFSSTGGAIYGEQDVFPAPESHPTRPISPYGVSKASGELYLGYYRAQYG
LPYVALRYANVYGPRQNPHGEAGVVAIFSQRLIAGQGCTIFGEGKQTRDFVFGPDVARANRLAFENDYVGAINIGTGVET
DINRLYALLAEAAGSSVSVAHAPGKPGEQMRSCVDNALARKVLGWEPSVDVREGLRRTLEYFRQKAGAPARAHG

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI7657641, Length=326, Percent_Identity=33.4355828220859, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI42516563, Length=309, Percent_Identity=26.8608414239482, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI56237023, Length=344, Percent_Identity=27.3255813953488, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI56118217, Length=344, Percent_Identity=27.3255813953488, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI189083684, Length=344, Percent_Identity=27.3255813953488, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI4504031, Length=250, Percent_Identity=26.4, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1786974, Length=338, Percent_Identity=31.9526627218935, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=30.8383233532934, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=29.4117647058824, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788366, Length=340, Percent_Identity=25.5882352941176, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788365, Length=327, Percent_Identity=25.0764525993884, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790049, Length=243, Percent_Identity=30.4526748971193, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=313, Percent_Identity=26.8370607028754, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17568069, Length=338, Percent_Identity=29.585798816568, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI115532424, Length=320, Percent_Identity=27.5, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71982035, Length=330, Percent_Identity=28.4848484848485, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319493, Length=335, Percent_Identity=25.6716417910448, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321437, Length=355, Percent_Identity=25.6338028169014, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21356223, Length=314, Percent_Identity=28.9808917197452, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19923002, Length=339, Percent_Identity=28.3185840707965, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 33898; Mature: 33898

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVTGGAGFIGSHVCDEFLRGGHDVIALDDLSGGKRENLDPRVRLAVHDIRSREASEL
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHEEHHHHHHHHHHHHHH
IKSEKPDVLCHLAAQMDVRRSVDDPSFDADVNIRGMLNLLEAARVSGVKKVIFSSTGGAI
HHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCE
YGEQDVFPAPESHPTRPISPYGVSKASGELYLGYYRAQYGLPYVALRYANVYGPRQNPHG
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHCCCCEEEEEEHHHCCCCCCCCC
EAGVVAIFSQRLIAGQGCTIFGEGKQTRDFVFGPDVARANRLAFENDYVGAINIGTGVET
CCHHHHHHHHHHHCCCCCEEEECCCCCCCEEECCCHHHHHHHEECCCCEEEEECCCCCCH
DINRLYALLAEAAGSSVSVAHAPGKPGEQMRSCVDNALARKVLGWEPSVDVREGLRRTLE
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
YFRQKAGAPARAHG
HHHHHCCCCCCCCC
>Mature Secondary Structure
MKVLVTGGAGFIGSHVCDEFLRGGHDVIALDDLSGGKRENLDPRVRLAVHDIRSREASEL
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHEEHHHHHHHHHHHHHH
IKSEKPDVLCHLAAQMDVRRSVDDPSFDADVNIRGMLNLLEAARVSGVKKVIFSSTGGAI
HHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCE
YGEQDVFPAPESHPTRPISPYGVSKASGELYLGYYRAQYGLPYVALRYANVYGPRQNPHG
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHCCCCEEEEEEHHHCCCCCCCCC
EAGVVAIFSQRLIAGQGCTIFGEGKQTRDFVFGPDVARANRLAFENDYVGAINIGTGVET
CCHHHHHHHHHHHCCCCCEEEECCCCCCCEEECCCHHHHHHHEECCCCEEEEECCCCCCH
DINRLYALLAEAAGSSVSVAHAPGKPGEQMRSCVDNALARKVLGWEPSVDVREGLRRTLE
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
YFRQKAGAPARAHG
HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]