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The map label for this gene is rnr [H]

Identifier: 108760400

GI number: 108760400

Start: 31391

End: 33286

Strand: Direct

Name: rnr [H]

Synonym: MXAN_0024

Alternate gene names: 108760400

Gene position: 31391-33286 (Clockwise)

Preceding gene: 108758631

Following gene: 108760513

Centisome position: 0.34

GC content: 71.47

Gene sequence:

>1896_bases
ATGGATACTTCTGTTTCGCCCCGCACCGTCACCGGCCGTCTCGACGTCCACCCTCGAGGCTTCGGCTTCCTCACCGTTCA
GACGCCCGGCTCGCCCGAGGTGCTGTCGGCCTTCGTCCCTCCGCCCGACCTCAATCCGTACTTCGCCGGGGACGTCGTCA
CGGCCACGGTGACGGCGGGCGCGGATGGGCGCTGGTCGGCCAGCCAGTTGTCGTTGGTGGAGCGGCCTCGCACGCAGGTC
TACGGCGAGGTGGTGCTGCGCAAGGGCGTGACCCTGCTCCACGTGGACCGCGAGGTGGCCAACGCGGACTGGGTGCTCGA
CGCCGCGGGGACGCAGGTGCAGGCCGGTGACGCGGTGGTGGCGCGCATCGACGAAGGCAAGGTGGTGCTGCTCTACCGGG
TGGAGGAAGGGGAGGACCGCTCCCTGGAGCGCGTCATCGCCCGGCACGGGCTGCGAAAGGACTTCTCCGCGGAAGTCGTC
GAGGAAGCGCGGGGGGCGCGCGCGGTGCCGCATGCGGTGGGCGCGCGGAGGGACTTGCGGGACGTGCCCACGGTGACGGT
GGATGCGCCGTCCACGCGGGACATCGACGACGCGATTTCGGTGCTGCCGGCGGGGCCGGACGGGGCGCTGCGGCTTCTGG
TGTCCATCGCGGACGTGGGTGAGTACGTGAAGCAGGGCTCGGCGCTGGACGCCGAGGCACGTGAGCGGGCCACCAGCGTG
TACCTGGCGGGGCGCGTGCTGCCGATGTTGCCGGAAGCGTTGTCTTCGCACTGGCTGAGCCTGATGCCGGGCGAGGAGCG
GCTGTGCCTCACGGTAGAGCTGCGCATCGACCCGCAGGGCCGGGTGACGGCGGCGGACGTGTACGAGAGTGTCATCCGCT
CGTGGGCGCGGCTGAACTACGACGAGGTGGCCGCCTTCCTGGACCGGGGTGAGGTGTCGGCGCCCATGGAGCCGGTGCGC
GAGGTGATGCCGTGGTTCCGGCTGGCGGCGGCCCGGCTGGCGGTGGCGCGGGCCGCGCGAGGCGGCATGGAGTTCGCGCG
GGACGAGGCGCGCTTCACCTTCGACCAGGCGACGGGCGAGCTGTCCGGGCTGGTGAGTGAGAAGCCGACGTCGGCGCACG
CGATGATTGAGCGCTTCATGGTGGCGGCGAACGAGGCCATCGCCGGGTGGCTGCTGGCGCGCGGCCTGCCCGGGGTGTAC
CGCGTGCACGAGCAGCCGGACCCGTTGCGGGTGGCGGACCTGAATGCCTTCGCGGAGACGTCTGGTTTCGCGGCGGGCTT
CGGACGGGAGCTGACGCCGCTCGCGCTGGCGGCGTTCGACCGGCAGATCGCGGGCGCGGTGGCGGAGCCGGCGCTGCGTT
CGGTGCTGCGGCGCTCACTGGGCCCGTCGCGCTACACGGTGAAGCCGGGGCCGCACTTCGGCCTGGCAGCGCCGCTGTAC
CTGCACTTCACGTCACCGATTCGCCGGTACGCGGACCTGGCGGTGCACCGGACGTTGAAGGGGTACCTGCGTGGGCGCCG
GGACTTCGTGGATGAAGACCCGGGGATGGAGGCGCTCGCGGTGCACATCAACGCGAAGGCGCGCGCGTCGACGCGGGCGG
AGAACGACCGGCACCGCGAGTTGGAGGCGCGGTGGATGGCGGGGCACGTGGGCAAGCAGTTCCAGGCGCGTGTGACGCGG
GTGCGGCCCTTCGGCCTGGTGGTGCAGTTGGACGGCATGTTGGTGGAAGGTGTGGTGCCCGCGGATGCCCTGTCCGGAGG
CCCCTTCCGGCCGGACGCGCGCGAACTGTCCCTGGTGGGCAAGGAGCGGACCTTCACCGTGGGCATGCCGGTGACGGTGA
AGGTGACCTCCACCGACGAGCAGCTTGGACGCATTGAGCTGTCACTGGTCGAGTAA

Upstream 100 bases:

>100_bases
CGCAGGCCCTCCATGGGCCGTGCTCCCGGGGGCTGATATTTTCCCGCGCGAGCCCTGCTTTCCCAGGATGGGAGTGGGCT
AAACACGCGCCCAAGGTTCC

Downstream 100 bases:

>100_bases
CCGGCGCAGGTATGGGAGGGACGCCCGGATGAGCCTTCGTTGGGCCAAGGTTGCCATGTTGCTGACGGCCTGCGGCGGGG
CGGGCTATCGGTACGCTGGG

Product: 3'-5' exoribonuclease

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MDTSVSPRTVTGRLDVHPRGFGFLTVQTPGSPEVLSAFVPPPDLNPYFAGDVVTATVTAGADGRWSASQLSLVERPRTQV
YGEVVLRKGVTLLHVDREVANADWVLDAAGTQVQAGDAVVARIDEGKVVLLYRVEEGEDRSLERVIARHGLRKDFSAEVV
EEARGARAVPHAVGARRDLRDVPTVTVDAPSTRDIDDAISVLPAGPDGALRLLVSIADVGEYVKQGSALDAEARERATSV
YLAGRVLPMLPEALSSHWLSLMPGEERLCLTVELRIDPQGRVTAADVYESVIRSWARLNYDEVAAFLDRGEVSAPMEPVR
EVMPWFRLAAARLAVARAARGGMEFARDEARFTFDQATGELSGLVSEKPTSAHAMIERFMVAANEAIAGWLLARGLPGVY
RVHEQPDPLRVADLNAFAETSGFAAGFGRELTPLALAAFDRQIAGAVAEPALRSVLRRSLGPSRYTVKPGPHFGLAAPLY
LHFTSPIRRYADLAVHRTLKGYLRGRRDFVDEDPGMEALAVHINAKARASTRAENDRHRELEARWMAGHVGKQFQARVTR
VRPFGLVVQLDGMLVEGVVPADALSGGPFRPDARELSLVGKERTFTVGMPVTVKVTSTDEQLGRIELSLVE

Sequences:

>Translated_631_residues
MDTSVSPRTVTGRLDVHPRGFGFLTVQTPGSPEVLSAFVPPPDLNPYFAGDVVTATVTAGADGRWSASQLSLVERPRTQV
YGEVVLRKGVTLLHVDREVANADWVLDAAGTQVQAGDAVVARIDEGKVVLLYRVEEGEDRSLERVIARHGLRKDFSAEVV
EEARGARAVPHAVGARRDLRDVPTVTVDAPSTRDIDDAISVLPAGPDGALRLLVSIADVGEYVKQGSALDAEARERATSV
YLAGRVLPMLPEALSSHWLSLMPGEERLCLTVELRIDPQGRVTAADVYESVIRSWARLNYDEVAAFLDRGEVSAPMEPVR
EVMPWFRLAAARLAVARAARGGMEFARDEARFTFDQATGELSGLVSEKPTSAHAMIERFMVAANEAIAGWLLARGLPGVY
RVHEQPDPLRVADLNAFAETSGFAAGFGRELTPLALAAFDRQIAGAVAEPALRSVLRRSLGPSRYTVKPGPHFGLAAPLY
LHFTSPIRRYADLAVHRTLKGYLRGRRDFVDEDPGMEALAVHINAKARASTRAENDRHRELEARWMAGHVGKQFQARVTR
VRPFGLVVQLDGMLVEGVVPADALSGGPFRPDARELSLVGKERTFTVGMPVTVKVTSTDEQLGRIELSLVE
>Mature_631_residues
MDTSVSPRTVTGRLDVHPRGFGFLTVQTPGSPEVLSAFVPPPDLNPYFAGDVVTATVTAGADGRWSASQLSLVERPRTQV
YGEVVLRKGVTLLHVDREVANADWVLDAAGTQVQAGDAVVARIDEGKVVLLYRVEEGEDRSLERVIARHGLRKDFSAEVV
EEARGARAVPHAVGARRDLRDVPTVTVDAPSTRDIDDAISVLPAGPDGALRLLVSIADVGEYVKQGSALDAEARERATSV
YLAGRVLPMLPEALSSHWLSLMPGEERLCLTVELRIDPQGRVTAADVYESVIRSWARLNYDEVAAFLDRGEVSAPMEPVR
EVMPWFRLAAARLAVARAARGGMEFARDEARFTFDQATGELSGLVSEKPTSAHAMIERFMVAANEAIAGWLLARGLPGVY
RVHEQPDPLRVADLNAFAETSGFAAGFGRELTPLALAAFDRQIAGAVAEPALRSVLRRSLGPSRYTVKPGPHFGLAAPLY
LHFTSPIRRYADLAVHRTLKGYLRGRRDFVDEDPGMEALAVHINAKARASTRAENDRHRELEARWMAGHVGKQFQARVTR
VRPFGLVVQLDGMLVEGVVPADALSGGPFRPDARELSLVGKERTFTVGMPVTVKVTSTDEQLGRIELSLVE

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI134288890, Length=420, Percent_Identity=30.4761904761905, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI190014623, Length=484, Percent_Identity=27.4793388429752, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI190014625, Length=484, Percent_Identity=27.4793388429752, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI19115966, Length=408, Percent_Identity=27.9411764705882, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI219521928, Length=408, Percent_Identity=27.9411764705882, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI156105695, Length=377, Percent_Identity=27.0557029177719, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI156105693, Length=368, Percent_Identity=26.6304347826087, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI87082383, Length=651, Percent_Identity=29.8003072196621, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1787542, Length=634, Percent_Identity=28.391167192429, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI212645896, Length=488, Percent_Identity=29.0983606557377, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17553506, Length=457, Percent_Identity=27.7899343544858, Blast_Score=123, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324552, Length=440, Percent_Identity=27.2727272727273, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6323943, Length=450, Percent_Identity=22, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24649634, Length=339, Percent_Identity=33.0383480825959, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI19922976, Length=356, Percent_Identity=29.2134831460674, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24654597, Length=356, Percent_Identity=29.2134831460674, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24654592, Length=356, Percent_Identity=29.2134831460674, Blast_Score=146, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 68608; Mature: 68608

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSVSPRTVTGRLDVHPRGFGFLTVQTPGSPEVLSAFVPPPDLNPYFAGDVVTATVTAG
CCCCCCCCEEEEEEEECCCCEEEEEEECCCCHHHHEEECCCCCCCCCCCCCEEEEEEEEC
ADGRWSASQLSLVERPRTQVYGEVVLRKGVTLLHVDREVANADWVLDAAGTQVQAGDAVV
CCCCCCHHHHHHHHCCHHHHHHHHHHHCCCEEEEECHHHCCCCEEEECCCCEEECCCEEE
ARIDEGKVVLLYRVEEGEDRSLERVIARHGLRKDFSAEVVEEARGARAVPHAVGARRDLR
EEECCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHCCCCHHH
DVPTVTVDAPSTRDIDDAISVLPAGPDGALRLLVSIADVGEYVKQGSALDAEARERATSV
HCCEEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHE
YLAGRVLPMLPEALSSHWLSLMPGEERLCLTVELRIDPQGRVTAADVYESVIRSWARLNY
EECCCHHHHHHHHHHHHHEEECCCCCEEEEEEEEEECCCCCEEHHHHHHHHHHHHHHCCH
DEVAAFLDRGEVSAPMEPVREVMPWFRLAAARLAVARAARGGMEFARDEARFTFDQATGE
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEHHHCCH
LSGLVSEKPTSAHAMIERFMVAANEAIAGWLLARGLPGVYRVHEQPDPLRVADLNAFAET
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECHHHHHC
SGFAAGFGRELTPLALAAFDRQIAGAVAEPALRSVLRRSLGPSRYTVKPGPHFGLAAPLY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEE
LHFTSPIRRYADLAVHRTLKGYLRGRRDFVDEDPGMEALAVHINAKARASTRAENDRHRE
EEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHCCCCCHHHH
LEARWMAGHVGKQFQARVTRVRPFGLVVQLDGMLVEGVVPADALSGGPFRPDARELSLVG
HHHHHHHHHHCHHHHHHHHEECCEEEEEEECCEEEECCCCHHHCCCCCCCCCHHHHHEEC
KERTFTVGMPVTVKVTSTDEQLGRIELSLVE
CCEEEEECCCEEEEEECCHHHHCEEEEEEEC
>Mature Secondary Structure
MDTSVSPRTVTGRLDVHPRGFGFLTVQTPGSPEVLSAFVPPPDLNPYFAGDVVTATVTAG
CCCCCCCCEEEEEEEECCCCEEEEEEECCCCHHHHEEECCCCCCCCCCCCCEEEEEEEEC
ADGRWSASQLSLVERPRTQVYGEVVLRKGVTLLHVDREVANADWVLDAAGTQVQAGDAVV
CCCCCCHHHHHHHHCCHHHHHHHHHHHCCCEEEEECHHHCCCCEEEECCCCEEECCCEEE
ARIDEGKVVLLYRVEEGEDRSLERVIARHGLRKDFSAEVVEEARGARAVPHAVGARRDLR
EEECCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHHHCCCCHHH
DVPTVTVDAPSTRDIDDAISVLPAGPDGALRLLVSIADVGEYVKQGSALDAEARERATSV
HCCEEEECCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHE
YLAGRVLPMLPEALSSHWLSLMPGEERLCLTVELRIDPQGRVTAADVYESVIRSWARLNY
EECCCHHHHHHHHHHHHHEEECCCCCEEEEEEEEEECCCCCEEHHHHHHHHHHHHHHCCH
DEVAAFLDRGEVSAPMEPVREVMPWFRLAAARLAVARAARGGMEFARDEARFTFDQATGE
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEHHHCCH
LSGLVSEKPTSAHAMIERFMVAANEAIAGWLLARGLPGVYRVHEQPDPLRVADLNAFAET
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECHHHHHC
SGFAAGFGRELTPLALAAFDRQIAGAVAEPALRSVLRRSLGPSRYTVKPGPHFGLAAPLY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEE
LHFTSPIRRYADLAVHRTLKGYLRGRRDFVDEDPGMEALAVHINAKARASTRAENDRHRE
EEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHCCCCCHHHH
LEARWMAGHVGKQFQARVTRVRPFGLVVQLDGMLVEGVVPADALSGGPFRPDARELSLVG
HHHHHHHHHHCHHHHHHHHEECCEEEEEEECCEEEECCCCHHHCCCCCCCCCHHHHHEEC
KERTFTVGMPVTVKVTSTDEQLGRIELSLVE
CCEEEEECCCEEEEEECCHHHHCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]