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The map label for this gene is lgrD [H]

Identifier: 108759883

GI number: 108759883

Start: 5744578

End: 5747865

Strand: Direct

Name: lgrD [H]

Synonym: MXAN_4595

Alternate gene names: 108759883

Gene position: 5744578-5747865 (Clockwise)

Preceding gene: 108758230

Following gene: 108757828

Centisome position: 62.85

GC content: 68.04

Gene sequence:

>3288_bases
ATGTCACACCACGCCATCGAAGACATCTACCCGCTCTCGCCCCTGCAACAGGGGATGCTCTTCCACACCCTGTACGCTCC
CGAGGCAGGACAGTATTTCCTCCAGATTACGTGCACACTGGAGGGGCACGTGGAGCCGGCGCACTTCGAGGCAGCGTGGC
AGCACGTCCTCGATCAGCACCCAGCGCTGCGCACCTCGTTCACCTGGGAGGAGTTGGAGGAGCCCCTCCAGGTCGTCCAC
CGCGCCGTCTCCGTGCAGCTCACCCGGCGGGATTGGGGCCACCTCGCACCGAAGGCACAGCGTCGTGAGCTGACGGCCCT
CCTCGATGCGGATCGCCAGCGCGGGTTCGCGCTCGATCAGGCGCCGCTCATGCGGCTGCTCCTCATACGCACCGGCCCTC
GGACCCACACGTTCGTCTGGAGCTGTCATCACCTGCTGCTGGATGGCTGGTCACTCGGGCTGCTCCTCGAGGAGTGCCTC
GACGCGTACCACGCGCTCGTCCGGGGCGAGCGCCCTTCGCGCGGCGTCACGCGCCCCTATCGCGACTACATTGCCTGGCT
CCAACAGCAATCATCCGGGCAGGCGGAGCACTTCTGGCGCGAGCGGCTGGCAGGCTTCTCCTCACCCACGCCCCTGCCGG
TGGCGCGGGCCACGAAGGCCGAAGGCTCCTGGCATGGGCGCTCCTCACTCATTCTTTCCGAAGAGACCTCGGAGCAGCTC
CGCGCCCTCGCCCGGACGCACGCGCTGACGCCGAACACCTTCTTCCAAGGCATCTGGGCGCTGCTGCTCAGCCGCTATAG
CGGCCAGTCCGACGTCGTTTTTGGCACCACGGTGTCCGGACGGCCCGCCGACCTGCCTGGCGCGCAATCCATGGTGGGGA
TGTTCATCAACACCCAGCCCGTGCGGACGCGGGTCGATCCAGACGGCCTCGTCCTGCCATACCTCCAACAACTCCAGCGC
GAGCAGGCCGAGGCGCGCCAGTACGAGTACAGCTCGCTCGTGCAGATTCACGGCTGGAGCGAGGTGCCGCGCGGCCAGAA
CCTCTTCGAGACGCTGCTCGTCTTCGAGAGCTTCCCCTTCTCCCACGCCGAGACCTCGCCGGGCGGTGGCGCGACCGTCA
CGGACGTCGAGACCTACGACTTCACCAGCTACATCCTTCACATCGACGTTGTCCCCGGTCCTGCCTTCACCCTCCTGGCG
AGCTACGATCGCCGGCAGCTCGACGACGCGACGCTCGCGCGGCTGCTGACGCACTACGCGCGGCTGCTCGAGGAGCTGGC
CCATCACCCCGAGCGGCGCCTGGACGAACTCTCGATGCTGCCGGACGCCGAGCGCCGGCAGGTCCTGCTCGATTGGAACC
AGCAGCGGGCGGACTACCCGTTCAACAGCTCCATCCCCCAGCTCATCCAGGAGCAGGCCGCACGGACCCCGGACGCAATC
GCCGTGACCCACCGCGACGCCCAGCTCACCTACCGCGAGCTCAACGCCCGGTCCAACCAGCTGGCGCATCCGCTCATCGC
GGAAGGCGTGGGGTCAGACATCGTCGTCGCGCTGCTCGGCGATCGAGGGGTGGACTTCCTCGCCTCCATCGTCGGGATTC
TCAAGGCGGGAGGCGCCTACCTCCCGTTGGATCCGGACCACCCTGCCGAGCGGTTGGCGCAGATCCTCGGGCAGAGCCAG
ACCCCCATGGTGGTGGTGTCCCGAGAACGCCGCGCGCTGCTCGACGCGGCGCTGGCGCTCCTGCCCGCCGGTGCCCGGCC
ACGCGCGTTGGAGATCCCGGAGTTGCTGGAGCGCCAGGCCCCAGCGGACGATCCGCCTTGCCGCAGCCACGGGCGGAACC
TGGCGTATGTCATCTACACGTCCGGCTCCACGGGCGCCCCCAAGGGCGCCATGCTGGAGCACGCTGGGAAGATCAACCAC
ATCCGCGGCATGATTGATTTCCTGCGGCTGGGGCCAGCGGACGTGATGGCTCAAACGGCCTCACAGTGCTTTGACATCTC
GGTCTGGCAGTTCCTCGCCCCGTTGATGCTGGGAGCACGAGTCCAGATCCTCGACACCGAACTGACGCGGGATCCCGCCA
GCTTCCTGGCGGAGTTGGACCGGACAGGCATCACCGTCCTCGAGGTGGTTCCCGCGTTGCTGACGGCGATGCTTGAGCAG
CTCGAGCGGATGGACCCCGCGCGGTTGCCGATGCAGTCGCTCCACTGCCTCATTCCCACCGGCGAGGTGCTCCCGCCCGC
GCTTTGCAGACGGTGGCTGAAACTGTACCCGCGCGTGCCGCTGCTCAATGCCTACGGCCCGACGGAGACCTCGGACGACA
CGAACCTCTACACGGTGTCCCAGCCACCACCGGACGACGAGGAGCGCGTGCCGGTCGGCTACGCGCTGCCGAACCTGACG
ATGTACATCCTGGATCCGCGGCTGCGTCCCGTGCCTGTTGGGCTCGCTGGGGAGCTGTACATTGGCGGCATCGGGGTGGG
CCGCGGCTACCTGAACAACCCCGCGCGCACGGCCGCATCGTTCCTACCGGATCCGTTCTCCGCCCTCAGCGGAGCGCGCT
TCTACAAGACGGGCGACATCTGCCGCTATCGCCCCGACGGAAGCATCGAGTTCCTCGACCGGGCGGACTTCCAGGTGAAG
ATCCGTGGCTTCCGGGTGGAGCCAGGTGAGGTGGAGTCGGTGCTCGCCCGGCACCCAACGGTCAGGCAAGCCGTGGTGGT
GGCTCGCGAGTTGCCAACCCGCGGCAAACAACTGGTCGCCTATGTGGTACCGTACGAGGGGACCTGGCCCGGTGCTGCCG
GGGGCGGCCCCCGCGACGGCCACGAGGGCATCACAGTCCTCCGTGAGTTCCTCCAGGGACATCTGCCGCACTACATGATG
CCCTCGGTCTTCGTCGTGTTGCCCGCGTTGCCGCTGAACGCCAACGGGAAGGTGGACCGCAAGGCGTTGCCCATGCCGGA
CGCCGCCGCTGCCCAGGAAGAGCGTGCGCCCTCGCCCCCCCGCTCCGATGTGGAGGAGCGGCTCGTGGCGCTCTGGCAAG
AGGTGCTGTCGCGCCAGTCCATTGGCGTCGAGGATGACTTCTTCGAGCTCGGCGGTCACTCGCTGCTCGCTGTCCGCGCG
CACTCCCGGCTGCGGGAACTCTTCGGCATCGACCTGCCGCTGCGGACCCTGTTCGAGCTGACCACCGTGGCCCGGCTGGC
CGAGAAGATCGAGGCCCTCCGCTGGGCGACCTCGGGCCCTCCCAAGGACGAGCCGGAGGACGTCGAGCGCGAAGAGGTGG
AGTTGTGA

Upstream 100 bases:

>100_bases
ACGTGTCCCCTGGATTGAACTGCCATTGAAAGAACGGTACCTCTCACATTGCCGCCCTGCTCGCGGCGTCTCCCTCTCAA
CGAACCGGACGGGCTGACTG

Downstream 100 bases:

>100_bases
CAGTCCTCGAACTGGTCACAGAGCTGCGCCAGCGCGGCGTGAGGCTGTGGCTGGAGCAAGAGCAGCTCCGTTGCAGCGCG
CCCAAGGGCGTGCTCACCGA

Product: non-ribosomal peptide synthase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1095; Mature: 1094

Protein sequence:

>1095_residues
MSHHAIEDIYPLSPLQQGMLFHTLYAPEAGQYFLQITCTLEGHVEPAHFEAAWQHVLDQHPALRTSFTWEELEEPLQVVH
RAVSVQLTRRDWGHLAPKAQRRELTALLDADRQRGFALDQAPLMRLLLIRTGPRTHTFVWSCHHLLLDGWSLGLLLEECL
DAYHALVRGERPSRGVTRPYRDYIAWLQQQSSGQAEHFWRERLAGFSSPTPLPVARATKAEGSWHGRSSLILSEETSEQL
RALARTHALTPNTFFQGIWALLLSRYSGQSDVVFGTTVSGRPADLPGAQSMVGMFINTQPVRTRVDPDGLVLPYLQQLQR
EQAEARQYEYSSLVQIHGWSEVPRGQNLFETLLVFESFPFSHAETSPGGGATVTDVETYDFTSYILHIDVVPGPAFTLLA
SYDRRQLDDATLARLLTHYARLLEELAHHPERRLDELSMLPDAERRQVLLDWNQQRADYPFNSSIPQLIQEQAARTPDAI
AVTHRDAQLTYRELNARSNQLAHPLIAEGVGSDIVVALLGDRGVDFLASIVGILKAGGAYLPLDPDHPAERLAQILGQSQ
TPMVVVSRERRALLDAALALLPAGARPRALEIPELLERQAPADDPPCRSHGRNLAYVIYTSGSTGAPKGAMLEHAGKINH
IRGMIDFLRLGPADVMAQTASQCFDISVWQFLAPLMLGARVQILDTELTRDPASFLAELDRTGITVLEVVPALLTAMLEQ
LERMDPARLPMQSLHCLIPTGEVLPPALCRRWLKLYPRVPLLNAYGPTETSDDTNLYTVSQPPPDDEERVPVGYALPNLT
MYILDPRLRPVPVGLAGELYIGGIGVGRGYLNNPARTAASFLPDPFSALSGARFYKTGDICRYRPDGSIEFLDRADFQVK
IRGFRVEPGEVESVLARHPTVRQAVVVARELPTRGKQLVAYVVPYEGTWPGAAGGGPRDGHEGITVLREFLQGHLPHYMM
PSVFVVLPALPLNANGKVDRKALPMPDAAAAQEERAPSPPRSDVEERLVALWQEVLSRQSIGVEDDFFELGGHSLLAVRA
HSRLRELFGIDLPLRTLFELTTVARLAEKIEALRWATSGPPKDEPEDVEREEVEL

Sequences:

>Translated_1095_residues
MSHHAIEDIYPLSPLQQGMLFHTLYAPEAGQYFLQITCTLEGHVEPAHFEAAWQHVLDQHPALRTSFTWEELEEPLQVVH
RAVSVQLTRRDWGHLAPKAQRRELTALLDADRQRGFALDQAPLMRLLLIRTGPRTHTFVWSCHHLLLDGWSLGLLLEECL
DAYHALVRGERPSRGVTRPYRDYIAWLQQQSSGQAEHFWRERLAGFSSPTPLPVARATKAEGSWHGRSSLILSEETSEQL
RALARTHALTPNTFFQGIWALLLSRYSGQSDVVFGTTVSGRPADLPGAQSMVGMFINTQPVRTRVDPDGLVLPYLQQLQR
EQAEARQYEYSSLVQIHGWSEVPRGQNLFETLLVFESFPFSHAETSPGGGATVTDVETYDFTSYILHIDVVPGPAFTLLA
SYDRRQLDDATLARLLTHYARLLEELAHHPERRLDELSMLPDAERRQVLLDWNQQRADYPFNSSIPQLIQEQAARTPDAI
AVTHRDAQLTYRELNARSNQLAHPLIAEGVGSDIVVALLGDRGVDFLASIVGILKAGGAYLPLDPDHPAERLAQILGQSQ
TPMVVVSRERRALLDAALALLPAGARPRALEIPELLERQAPADDPPCRSHGRNLAYVIYTSGSTGAPKGAMLEHAGKINH
IRGMIDFLRLGPADVMAQTASQCFDISVWQFLAPLMLGARVQILDTELTRDPASFLAELDRTGITVLEVVPALLTAMLEQ
LERMDPARLPMQSLHCLIPTGEVLPPALCRRWLKLYPRVPLLNAYGPTETSDDTNLYTVSQPPPDDEERVPVGYALPNLT
MYILDPRLRPVPVGLAGELYIGGIGVGRGYLNNPARTAASFLPDPFSALSGARFYKTGDICRYRPDGSIEFLDRADFQVK
IRGFRVEPGEVESVLARHPTVRQAVVVARELPTRGKQLVAYVVPYEGTWPGAAGGGPRDGHEGITVLREFLQGHLPHYMM
PSVFVVLPALPLNANGKVDRKALPMPDAAAAQEERAPSPPRSDVEERLVALWQEVLSRQSIGVEDDFFELGGHSLLAVRA
HSRLRELFGIDLPLRTLFELTTVARLAEKIEALRWATSGPPKDEPEDVEREEVEL
>Mature_1094_residues
SHHAIEDIYPLSPLQQGMLFHTLYAPEAGQYFLQITCTLEGHVEPAHFEAAWQHVLDQHPALRTSFTWEELEEPLQVVHR
AVSVQLTRRDWGHLAPKAQRRELTALLDADRQRGFALDQAPLMRLLLIRTGPRTHTFVWSCHHLLLDGWSLGLLLEECLD
AYHALVRGERPSRGVTRPYRDYIAWLQQQSSGQAEHFWRERLAGFSSPTPLPVARATKAEGSWHGRSSLILSEETSEQLR
ALARTHALTPNTFFQGIWALLLSRYSGQSDVVFGTTVSGRPADLPGAQSMVGMFINTQPVRTRVDPDGLVLPYLQQLQRE
QAEARQYEYSSLVQIHGWSEVPRGQNLFETLLVFESFPFSHAETSPGGGATVTDVETYDFTSYILHIDVVPGPAFTLLAS
YDRRQLDDATLARLLTHYARLLEELAHHPERRLDELSMLPDAERRQVLLDWNQQRADYPFNSSIPQLIQEQAARTPDAIA
VTHRDAQLTYRELNARSNQLAHPLIAEGVGSDIVVALLGDRGVDFLASIVGILKAGGAYLPLDPDHPAERLAQILGQSQT
PMVVVSRERRALLDAALALLPAGARPRALEIPELLERQAPADDPPCRSHGRNLAYVIYTSGSTGAPKGAMLEHAGKINHI
RGMIDFLRLGPADVMAQTASQCFDISVWQFLAPLMLGARVQILDTELTRDPASFLAELDRTGITVLEVVPALLTAMLEQL
ERMDPARLPMQSLHCLIPTGEVLPPALCRRWLKLYPRVPLLNAYGPTETSDDTNLYTVSQPPPDDEERVPVGYALPNLTM
YILDPRLRPVPVGLAGELYIGGIGVGRGYLNNPARTAASFLPDPFSALSGARFYKTGDICRYRPDGSIEFLDRADFQVKI
RGFRVEPGEVESVLARHPTVRQAVVVARELPTRGKQLVAYVVPYEGTWPGAAGGGPRDGHEGITVLREFLQGHLPHYMMP
SVFVVLPALPLNANGKVDRKALPMPDAAAAQEERAPSPPRSDVEERLVALWQEVLSRQSIGVEDDFFELGGHSLLAVRAH
SRLRELFGIDLPLRTLFELTTVARLAEKIEALRWATSGPPKDEPEDVEREEVEL

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI38505220, Length=522, Percent_Identity=26.8199233716475, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI187761345, Length=545, Percent_Identity=25.8715596330275, Blast_Score=113, Evalue=1e-24,
Organism=Homo sapiens, GI187761343, Length=545, Percent_Identity=25.8715596330275, Blast_Score=113, Evalue=1e-24,
Organism=Homo sapiens, GI42544132, Length=543, Percent_Identity=23.9410681399632, Blast_Score=107, Evalue=6e-23,
Organism=Homo sapiens, GI45580730, Length=502, Percent_Identity=25.2988047808765, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI58082049, Length=607, Percent_Identity=23.3937397034596, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI156151445, Length=579, Percent_Identity=22.6252158894646, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI157311624, Length=607, Percent_Identity=23.0642504118616, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI157311622, Length=607, Percent_Identity=23.0642504118616, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI115511026, Length=524, Percent_Identity=22.9007633587786, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI122937307, Length=525, Percent_Identity=24.3809523809524, Blast_Score=75, Evalue=4e-13,
Organism=Escherichia coli, GI1786801, Length=1000, Percent_Identity=30.3, Blast_Score=327, Evalue=2e-90,
Organism=Escherichia coli, GI145693145, Length=556, Percent_Identity=26.4388489208633, Blast_Score=126, Evalue=6e-30,
Organism=Escherichia coli, GI1788107, Length=562, Percent_Identity=24.5551601423488, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI221142682, Length=531, Percent_Identity=24.8587570621469, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1786810, Length=531, Percent_Identity=23.728813559322, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1790505, Length=593, Percent_Identity=21.247892074199, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17556356, Length=606, Percent_Identity=25.9075907590759, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71994690, Length=370, Percent_Identity=25.9459459459459, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71994703, Length=373, Percent_Identity=26.5415549597855, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71994694, Length=370, Percent_Identity=25.9459459459459, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17557194, Length=589, Percent_Identity=23.5993208828523, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17538037, Length=561, Percent_Identity=23.8859180035651, Blast_Score=93, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17560140, Length=468, Percent_Identity=24.1452991452991, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17531443, Length=499, Percent_Identity=21.6432865731463, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560308, Length=571, Percent_Identity=22.7670753064799, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17559526, Length=323, Percent_Identity=26.0061919504644, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551278, Length=520, Percent_Identity=23.2692307692308, Blast_Score=77, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71983001, Length=544, Percent_Identity=23.5294117647059, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71982997, Length=544, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=896, Percent_Identity=24.8883928571429, Blast_Score=235, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6319699, Length=561, Percent_Identity=21.3903743315508, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24648676, Length=656, Percent_Identity=28.9634146341463, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24667955, Length=515, Percent_Identity=23.3009708737864, Blast_Score=84, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24667959, Length=515, Percent_Identity=23.3009708737864, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24581924, Length=382, Percent_Identity=22.5130890052356, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI62472339, Length=516, Percent_Identity=23.6434108527132, Blast_Score=82, Evalue=3e-15,
Organism=Drosophila melanogaster, GI18859661, Length=390, Percent_Identity=24.3589743589744, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24648257, Length=534, Percent_Identity=23.2209737827715, Blast_Score=79, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24656500, Length=434, Percent_Identity=22.8110599078341, Blast_Score=77, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 121839; Mature: 121708

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHHAIEDIYPLSPLQQGMLFHTLYAPEAGQYFLQITCTLEGHVEPAHFEAAWQHVLDQH
CCCCCCHHCCCCCHHHHCCEEEEEECCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCC
PALRTSFTWEELEEPLQVVHRAVSVQLTRRDWGHLAPKAQRRELTALLDADRQRGFALDQ
CCCCCCCCHHHHHHHHHHHHHHHHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCH
APLMRLLLIRTGPRTHTFVWSCHHLLLDGWSLGLLLEECLDAYHALVRGERPSRGVTRPY
HHHHHHHHHHCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
RDYIAWLQQQSSGQAEHFWRERLAGFSSPTPLPVARATKAEGSWHGRSSLILSEETSEQL
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHH
RALARTHALTPNTFFQGIWALLLSRYSGQSDVVFGTTVSGRPADLPGAQSMVGMFINTQP
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCC
VRTRVDPDGLVLPYLQQLQREQAEARQYEYSSLVQIHGWSEVPRGQNLFETLLVFESFPF
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHCCCC
SHAETSPGGGATVTDVETYDFTSYILHIDVVPGPAFTLLASYDRRQLDDATLARLLTHYA
CCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
RLLEELAHHPERRLDELSMLPDAERRQVLLDWNQQRADYPFNSSIPQLIQEQAARTPDAI
HHHHHHHHCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCEE
AVTHRDAQLTYRELNARSNQLAHPLIAEGVGSDIVVALLGDRGVDFLASIVGILKAGGAY
EEEECCHHHHHHHHCCCHHHHCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCC
LPLDPDHPAERLAQILGQSQTPMVVVSRERRALLDAALALLPAGARPRALEIPELLERQA
CCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCC
PADDPPCRSHGRNLAYVIYTSGSTGAPKGAMLEHAGKINHIRGMIDFLRLGPADVMAQTA
CCCCCCHHHCCCEEEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHH
SQCFDISVWQFLAPLMLGARVQILDTELTRDPASFLAELDRTGITVLEVVPALLTAMLEQ
HHHHHHHHHHHHHHHHHCCEEEEECCHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LERMDPARLPMQSLHCLIPTGEVLPPALCRRWLKLYPRVPLLNAYGPTETSDDTNLYTVS
HHHCCCCCCCHHHCEEECCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEECC
QPPPDDEERVPVGYALPNLTMYILDPRLRPVPVGLAGELYIGGIGVGRGYLNNPARTAAS
CCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHH
FLPDPFSALSGARFYKTGDICRYRPDGSIEFLDRADFQVKIRGFRVEPGEVESVLARHPT
HCCCCHHHHCCCCEEECCCEEEECCCCCEEEECCCCEEEEEEEEECCCHHHHHHHHCCCH
VRQAVVVARELPTRGKQLVAYVVPYEGTWPGAAGGGPRDGHEGITVLREFLQGHLPHYMM
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
PSVFVVLPALPLNANGKVDRKALPMPDAAAAQEERAPSPPRSDVEERLVALWQEVLSRQS
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
IGVEDDFFELGGHSLLAVRAHSRLRELFGIDLPLRTLFELTTVARLAEKIEALRWATSGP
CCCCCHHHHHCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PKDEPEDVEREEVEL
CCCCCCCCCHHHCCC
>Mature Secondary Structure 
SHHAIEDIYPLSPLQQGMLFHTLYAPEAGQYFLQITCTLEGHVEPAHFEAAWQHVLDQH
CCCCCHHCCCCCHHHHCCEEEEEECCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCC
PALRTSFTWEELEEPLQVVHRAVSVQLTRRDWGHLAPKAQRRELTALLDADRQRGFALDQ
CCCCCCCCHHHHHHHHHHHHHHHHHEEHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCH
APLMRLLLIRTGPRTHTFVWSCHHLLLDGWSLGLLLEECLDAYHALVRGERPSRGVTRPY
HHHHHHHHHHCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
RDYIAWLQQQSSGQAEHFWRERLAGFSSPTPLPVARATKAEGSWHGRSSLILSEETSEQL
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHH
RALARTHALTPNTFFQGIWALLLSRYSGQSDVVFGTTVSGRPADLPGAQSMVGMFINTQP
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCC
VRTRVDPDGLVLPYLQQLQREQAEARQYEYSSLVQIHGWSEVPRGQNLFETLLVFESFPF
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHCCCC
SHAETSPGGGATVTDVETYDFTSYILHIDVVPGPAFTLLASYDRRQLDDATLARLLTHYA
CCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
RLLEELAHHPERRLDELSMLPDAERRQVLLDWNQQRADYPFNSSIPQLIQEQAARTPDAI
HHHHHHHHCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCEE
AVTHRDAQLTYRELNARSNQLAHPLIAEGVGSDIVVALLGDRGVDFLASIVGILKAGGAY
EEEECCHHHHHHHHCCCHHHHCCHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCC
LPLDPDHPAERLAQILGQSQTPMVVVSRERRALLDAALALLPAGARPRALEIPELLERQA
CCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCC
PADDPPCRSHGRNLAYVIYTSGSTGAPKGAMLEHAGKINHIRGMIDFLRLGPADVMAQTA
CCCCCCHHHCCCEEEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHH
SQCFDISVWQFLAPLMLGARVQILDTELTRDPASFLAELDRTGITVLEVVPALLTAMLEQ
HHHHHHHHHHHHHHHHHCCEEEEECCHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LERMDPARLPMQSLHCLIPTGEVLPPALCRRWLKLYPRVPLLNAYGPTETSDDTNLYTVS
HHHCCCCCCCHHHCEEECCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEECC
QPPPDDEERVPVGYALPNLTMYILDPRLRPVPVGLAGELYIGGIGVGRGYLNNPARTAAS
CCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHH
FLPDPFSALSGARFYKTGDICRYRPDGSIEFLDRADFQVKIRGFRVEPGEVESVLARHPT
HCCCCHHHHCCCCEEECCCEEEECCCCCEEEECCCCEEEEEEEEECCCHHHHHHHHCCCH
VRQAVVVARELPTRGKQLVAYVVPYEGTWPGAAGGGPRDGHEGITVLREFLQGHLPHYMM
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
PSVFVVLPALPLNANGKVDRKALPMPDAAAAQEERAPSPPRSDVEERLVALWQEVLSRQS
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
IGVEDDFFELGGHSLLAVRAHSRLRELFGIDLPLRTLFELTTVARLAEKIEALRWATSGP
CCCCCHHHHHCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PKDEPEDVEREEVEL
CCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA