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The map label for this gene is clpB [H]

Identifier: 108759726

GI number: 108759726

Start: 6039087

End: 6041597

Strand: Direct

Name: clpB [H]

Synonym: MXAN_4825

Alternate gene names: 108759726

Gene position: 6039087-6041597 (Clockwise)

Preceding gene: 108759056

Following gene: 108760170

Centisome position: 66.07

GC content: 71.41

Gene sequence:

>2511_bases
ATGAGGCAGTCGTCCGCGAACGCGATGCCCGGAGGAGCGGCGCCGCGTCAGTGGGCGCGGCCAGCCACGTCATCCTGCGT
GGCCGCGAAGGTGTCACGACTGGGCGGCCCCACGACTCGACCGAACTCACGCACGTCGCGAGCGGACGCCGCCCCCGGGA
GGCGCTCGCATGGGCCGCGAGGGTGCTCCGGGAACCCAGCCAGGGACACGACTGACATGGAAAAGAACGTCCACCTCTTC
GTGCGCACCTATCCCGGGCTGGGCGTGGCGGCGCACGTCCTCACCCACCCGCACCTGGCGGCCTTCGCGCCGACGCTGCA
CGCCGCGAGGCTCGACATCGCTGCGGTGGTGGGGCGGCTCCTCAAGCGAGGAGAGCTCTGGGACGAGGAGACCCACTGGA
GCGATTTGCGCCAGCGGAAGACGACGCTGACGGTGCGCGCGCTCGAACACGGGAAGATGCTGTCCGTCCCCCTGCGCCTC
ACCGTGCTCACGCACGGGGTGAAGGCCCGCACCGCACGCAAGGGAGCACCAGCGCGCCAGTCCCTACGCGTGTGGGTGCC
CCGCGTGGACGTCAAGGGCACGCTGCACGATGCGGCGGACCTGGAGCCCTTCGTCGAGGAGATGGTCCGCCACGAGCTCT
ATCTCGCGTCGCTCGACCGGCTGCACTCTCTGGCCTACGTGGGCGAGGAGCAGGTAGAGACGCTGTCGGTGCCGGTCCGC
TTCCGGGACACGCCGCGTGCCCGTGCGCTCGATGCCGCGAAGCCGCAGCGGCGCCAGGCGCCACCACCGGGGCTCGCGGA
AGCCAGCCGGTGTCTCAATGAGGAAGCACGCGCGGGTTTGCTGGAGCGCGCCTGGGAACGGGACCTGGAGGTGTCCCGGC
TCGCGGAGGCCGTCACCTCGCGCACCCGTGCCAGCGTGCTCCTGGTAGGCCCGTCGTCCGTGGGCAAGACGGCCCTGGTT
CATGAACTCGTGCAACGCGCGGAGGCGGCCACCACGGGTTCGCCGCTTCACGGGTTGGAGGTCTTCAGCTCCTCCGGAGG
CCGCATCATGGCGGGCATGCGCTACCTGGGGCAGTGGCAGGAGCGCGTGAAGCACATGGTGGAGGCCCTGCGTGTTCGCC
AGGCCGTGCTGCACCTCGACAGCCTGTCGGAGCTGCTGTCCCTGGGTAGCGGCGACACGGGGCTGGATGTGGCGCGTCAG
TTGCTCCCCGCATTGGAAAGTGGCGAGGTCTCACTCGTCCTGGAGGCAACACCGGAGGACGTGGCCCGCGCGGAGCGGAC
CCACGCAGCGTTCCTGCAATCGCTCCGGCACATCGCCGTGGCGCCCCTTTCGGCCCAGGCCGCACGCAACGCGCTTCAGC
AGGCCTCGCATCGGGTGGGCCGCGCTCGCAAGGTGCGCTTCACGCCCGACGCGCTGGACCGCGCTGGCGAACTCACGGAG
CGCTTCGGCTCGGGCCCTTCGCCCGGAGGCGCGGTGTCCCTGCTGCGCGCCGCCAGCACGGAGCCCGGCGCGGCCGGAGA
AGTGAACGCCGCTTCGGTGACGCGCGCCTTCTGCACTCGGACGGGGTACCCGCTCGAACTGGTGGACTCCGCCATCCGGT
TGGACCCGGATGCCCTGCTCCGCCGCTTCCGCGAGCGCGTGGTGGGCCAGGACGAGGCCACCCTCCTCCTGCGCAATCTG
GTCGTCACGCTGAAAACAGGCCTGGCGGACCCCTCGCGTCCGCTGGGCGCCTTCCTGCTGCTGGGTCCCACCGGCGTGGG
CAAGACGGAGTCGGCGCTCGCGCTGGCGGAGTACCTGTTTGGCGACGTGGCCCGGCTGGCGCGCTTCGACATGGCGGAGT
ACGCCGCGCCAGGCAGCGCCACCCGGCTGGTGGGAGAAGCGGGAGGCCAACAAGGCAGCCTGGCGCGGCGCGTCCGCGAG
CAGCCCTTCGGCGTGGTGCTGCTGGACGAAATCGAGAAAGCGGACGCGGGCGTCCATGACCTGCTGTTGCAGGTGCTCGG
CGAAGGCCGGCTCACGGATGCCACCGGCCGCACCGTCAGCTTCCGCAACACCGTGGTGCTGCTCACCAGCAACCTGGGCG
CGGACAGCGCGGGGCGCTCGCTGGGTTTCGGGGAGCGCGGCCCCCTGGAGCGGGCGGCGCACTACCTGGGGGCCGCGGCG
GCCTTCTTCCGGCCGGAGTTGCTGAACCGGTTGGACCGGGTGGTGCCCTACCGCGCGCTCACGGAGGACGTCATTCAATC
ACTCGCCCGGCGCACGTTGGAGGCGGCCCTCTCTCGCGAGGGGCTCAGTCGCCGGGGCGTGAAGGTGACCTTCGACGAGG
ACGTGGTGAAGCACCTGGCGCGCACCGGCTTCGACGCACGCTATGGGGCCAGGCCTCTCAAGCGCGCCGTGGAGCAACAG
GTGGTCGCGCCCCTGGCGCGGTGGTTGGCGGCTCAGGCCACCAGCGCTCCGCCCCAGGTGGTGCTCCGCGTGGAAGCTGA
GGGGCGGATTGCGTTGAGCGGCCTCGAATGA

Upstream 100 bases:

>100_bases
GTCTATGGCGATGGGCCACGCCAGGTCCTGGTCCGGCTGGAGCACCTGTCCGAAGACGTCGGGAGTCTGGAAGACGTGCC
GCGCGTGATGGCCGCATGGG

Downstream 100 bases:

>100_bases
CCTCCGAGGCCGCCCAGGCCAGCGATGGACGCCGTGCGGCGCGAACTAGCCCTTGAAGTTCTGGGCCACGAAGTCCCAGT
TCACCAGGTGCGTCAGGAAC

Product: ClpA/B family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 836; Mature: 836

Protein sequence:

>836_residues
MRQSSANAMPGGAAPRQWARPATSSCVAAKVSRLGGPTTRPNSRTSRADAAPGRRSHGPRGCSGNPARDTTDMEKNVHLF
VRTYPGLGVAAHVLTHPHLAAFAPTLHAARLDIAAVVGRLLKRGELWDEETHWSDLRQRKTTLTVRALEHGKMLSVPLRL
TVLTHGVKARTARKGAPARQSLRVWVPRVDVKGTLHDAADLEPFVEEMVRHELYLASLDRLHSLAYVGEEQVETLSVPVR
FRDTPRARALDAAKPQRRQAPPPGLAEASRCLNEEARAGLLERAWERDLEVSRLAEAVTSRTRASVLLVGPSSVGKTALV
HELVQRAEAATTGSPLHGLEVFSSSGGRIMAGMRYLGQWQERVKHMVEALRVRQAVLHLDSLSELLSLGSGDTGLDVARQ
LLPALESGEVSLVLEATPEDVARAERTHAAFLQSLRHIAVAPLSAQAARNALQQASHRVGRARKVRFTPDALDRAGELTE
RFGSGPSPGGAVSLLRAASTEPGAAGEVNAASVTRAFCTRTGYPLELVDSAIRLDPDALLRRFRERVVGQDEATLLLRNL
VVTLKTGLADPSRPLGAFLLLGPTGVGKTESALALAEYLFGDVARLARFDMAEYAAPGSATRLVGEAGGQQGSLARRVRE
QPFGVVLLDEIEKADAGVHDLLLQVLGEGRLTDATGRTVSFRNTVVLLTSNLGADSAGRSLGFGERGPLERAAHYLGAAA
AFFRPELLNRLDRVVPYRALTEDVIQSLARRTLEAALSREGLSRRGVKVTFDEDVVKHLARTGFDARYGARPLKRAVEQQ
VVAPLARWLAAQATSAPPQVVLRVEAEGRIALSGLE

Sequences:

>Translated_836_residues
MRQSSANAMPGGAAPRQWARPATSSCVAAKVSRLGGPTTRPNSRTSRADAAPGRRSHGPRGCSGNPARDTTDMEKNVHLF
VRTYPGLGVAAHVLTHPHLAAFAPTLHAARLDIAAVVGRLLKRGELWDEETHWSDLRQRKTTLTVRALEHGKMLSVPLRL
TVLTHGVKARTARKGAPARQSLRVWVPRVDVKGTLHDAADLEPFVEEMVRHELYLASLDRLHSLAYVGEEQVETLSVPVR
FRDTPRARALDAAKPQRRQAPPPGLAEASRCLNEEARAGLLERAWERDLEVSRLAEAVTSRTRASVLLVGPSSVGKTALV
HELVQRAEAATTGSPLHGLEVFSSSGGRIMAGMRYLGQWQERVKHMVEALRVRQAVLHLDSLSELLSLGSGDTGLDVARQ
LLPALESGEVSLVLEATPEDVARAERTHAAFLQSLRHIAVAPLSAQAARNALQQASHRVGRARKVRFTPDALDRAGELTE
RFGSGPSPGGAVSLLRAASTEPGAAGEVNAASVTRAFCTRTGYPLELVDSAIRLDPDALLRRFRERVVGQDEATLLLRNL
VVTLKTGLADPSRPLGAFLLLGPTGVGKTESALALAEYLFGDVARLARFDMAEYAAPGSATRLVGEAGGQQGSLARRVRE
QPFGVVLLDEIEKADAGVHDLLLQVLGEGRLTDATGRTVSFRNTVVLLTSNLGADSAGRSLGFGERGPLERAAHYLGAAA
AFFRPELLNRLDRVVPYRALTEDVIQSLARRTLEAALSREGLSRRGVKVTFDEDVVKHLARTGFDARYGARPLKRAVEQQ
VVAPLARWLAAQATSAPPQVVLRVEAEGRIALSGLE
>Mature_836_residues
MRQSSANAMPGGAAPRQWARPATSSCVAAKVSRLGGPTTRPNSRTSRADAAPGRRSHGPRGCSGNPARDTTDMEKNVHLF
VRTYPGLGVAAHVLTHPHLAAFAPTLHAARLDIAAVVGRLLKRGELWDEETHWSDLRQRKTTLTVRALEHGKMLSVPLRL
TVLTHGVKARTARKGAPARQSLRVWVPRVDVKGTLHDAADLEPFVEEMVRHELYLASLDRLHSLAYVGEEQVETLSVPVR
FRDTPRARALDAAKPQRRQAPPPGLAEASRCLNEEARAGLLERAWERDLEVSRLAEAVTSRTRASVLLVGPSSVGKTALV
HELVQRAEAATTGSPLHGLEVFSSSGGRIMAGMRYLGQWQERVKHMVEALRVRQAVLHLDSLSELLSLGSGDTGLDVARQ
LLPALESGEVSLVLEATPEDVARAERTHAAFLQSLRHIAVAPLSAQAARNALQQASHRVGRARKVRFTPDALDRAGELTE
RFGSGPSPGGAVSLLRAASTEPGAAGEVNAASVTRAFCTRTGYPLELVDSAIRLDPDALLRRFRERVVGQDEATLLLRNL
VVTLKTGLADPSRPLGAFLLLGPTGVGKTESALALAEYLFGDVARLARFDMAEYAAPGSATRLVGEAGGQQGSLARRVRE
QPFGVVLLDEIEKADAGVHDLLLQVLGEGRLTDATGRTVSFRNTVVLLTSNLGADSAGRSLGFGERGPLERAAHYLGAAA
AFFRPELLNRLDRVVPYRALTEDVIQSLARRTLEAALSREGLSRRGVKVTFDEDVVKHLARTGFDARYGARPLKRAVEQQ
VVAPLARWLAAQATSAPPQVVLRVEAEGRIALSGLE

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=321, Percent_Identity=28.3489096573209, Blast_Score=125, Evalue=2e-28,
Organism=Escherichia coli, GI1788943, Length=431, Percent_Identity=36.6589327146172, Blast_Score=235, Evalue=8e-63,
Organism=Escherichia coli, GI1787109, Length=572, Percent_Identity=28.3216783216783, Blast_Score=209, Evalue=7e-55,
Organism=Saccharomyces cerevisiae, GI6320464, Length=413, Percent_Identity=32.9297820823245, Blast_Score=209, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6323002, Length=345, Percent_Identity=28.4057971014493, Blast_Score=150, Evalue=6e-37,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 90100; Mature: 90100

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQSSANAMPGGAAPRQWARPATSSCVAAKVSRLGGPTTRPNSRTSRADAAPGRRSHGPR
CCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
GCSGNPARDTTDMEKNVHLFVRTYPGLGVAAHVLTHPHLAAFAPTLHAARLDIAAVVGRL
CCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LKRGELWDEETHWSDLRQRKTTLTVRALEHGKMLSVPLRLTVLTHGVKARTARKGAPARQ
HHCCCCCCCHHHHHHHHHHHHHHEEEECCCCCEEECCCEEEHHHCCHHHHHHHCCCCCCC
SLRVWVPRVDVKGTLHDAADLEPFVEEMVRHELYLASLDRLHSLAYVGEEQVETLSVPVR
CCEEEEECCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCEE
FRDTPRARALDAAKPQRRQAPPPGLAEASRCLNEEARAGLLERAWERDLEVSRLAEAVTS
ECCCCCHHHHCCCCCHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHH
RTRASVLLVGPSSVGKTALVHELVQRAEAATTGSPLHGLEVFSSSGGRIMAGMRYLGQWQ
HHHCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHH
ERVKHMVEALRVRQAVLHLDSLSELLSLGSGDTGLDVARQLLPALESGEVSLVLEATPED
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHH
VARAERTHAAFLQSLRHIAVAPLSAQAARNALQQASHRVGRARKVRFTPDALDRAGELTE
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHH
RFGSGPSPGGAVSLLRAASTEPGAAGEVNAASVTRAFCTRTGYPLELVDSAIRLDPDALL
HHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHH
RRFRERVVGQDEATLLLRNLVVTLKTGLADPSRPLGAFLLLGPTGVGKTESALALAEYLF
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
GDVARLARFDMAEYAAPGSATRLVGEAGGQQGSLARRVREQPFGVVLLDEIEKADAGVHD
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCEEEHHHHHHHCCCHHH
LLLQVLGEGRLTDATGRTVSFRNTVVLLTSNLGADSAGRSLGFGERGPLERAAHYLGAAA
HHHHHHCCCCEECCCCCEEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AFFRPELLNRLDRVVPYRALTEDVIQSLARRTLEAALSREGLSRRGVKVTFDEDVVKHLA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEHHHHHHHHH
RTGFDARYGARPLKRAVEQQVVAPLARWLAAQATSAPPQVVLRVEAEGRIALSGLE
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCC
>Mature Secondary Structure
MRQSSANAMPGGAAPRQWARPATSSCVAAKVSRLGGPTTRPNSRTSRADAAPGRRSHGPR
CCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
GCSGNPARDTTDMEKNVHLFVRTYPGLGVAAHVLTHPHLAAFAPTLHAARLDIAAVVGRL
CCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LKRGELWDEETHWSDLRQRKTTLTVRALEHGKMLSVPLRLTVLTHGVKARTARKGAPARQ
HHCCCCCCCHHHHHHHHHHHHHHEEEECCCCCEEECCCEEEHHHCCHHHHHHHCCCCCCC
SLRVWVPRVDVKGTLHDAADLEPFVEEMVRHELYLASLDRLHSLAYVGEEQVETLSVPVR
CCEEEEECCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCEE
FRDTPRARALDAAKPQRRQAPPPGLAEASRCLNEEARAGLLERAWERDLEVSRLAEAVTS
ECCCCCHHHHCCCCCHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHH
RTRASVLLVGPSSVGKTALVHELVQRAEAATTGSPLHGLEVFSSSGGRIMAGMRYLGQWQ
HHHCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHH
ERVKHMVEALRVRQAVLHLDSLSELLSLGSGDTGLDVARQLLPALESGEVSLVLEATPED
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHH
VARAERTHAAFLQSLRHIAVAPLSAQAARNALQQASHRVGRARKVRFTPDALDRAGELTE
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHH
RFGSGPSPGGAVSLLRAASTEPGAAGEVNAASVTRAFCTRTGYPLELVDSAIRLDPDALL
HHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHH
RRFRERVVGQDEATLLLRNLVVTLKTGLADPSRPLGAFLLLGPTGVGKTESALALAEYLF
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
GDVARLARFDMAEYAAPGSATRLVGEAGGQQGSLARRVREQPFGVVLLDEIEKADAGVHD
HHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCEEEHHHHHHHCCCHHH
LLLQVLGEGRLTDATGRTVSFRNTVVLLTSNLGADSAGRSLGFGERGPLERAAHYLGAAA
HHHHHHCCCCEECCCCCEEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AFFRPELLNRLDRVVPYRALTEDVIQSLARRTLEAALSREGLSRRGVKVTFDEDVVKHLA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEHHHHHHHHH
RTGFDARYGARPLKRAVEQQVVAPLARWLAAQATSAPPQVVLRVEAEGRIALSGLE
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]