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The map label for this gene is fliP [C]

Identifier: 108758905

GI number: 108758905

Start: 7014802

End: 7015458

Strand: Reverse

Name: fliP [C]

Synonym: MXAN_5647

Alternate gene names: 108758905

Gene position: 7015458-7014802 (Counterclockwise)

Preceding gene: 108759924

Following gene: 108761227

Centisome position: 76.76

GC content: 66.21

Gene sequence:

>657_bases
ATGTCGTACGCGGGCAGCCCTCTGTCGATGATGGGCATGCTCGCGGTGATGTCGCTGCTGCCGTTCGCGGTGCTGATGCT
GACGAGCTTCTCGAAGATTGCCGTCGTATTGTCGCTGGCCCGCTCGGCCATGGGCACGCAGCAGGCGCCGCCTACCATCG
TGCTCACGGGCCTGGCGGCGGTGCTCACCGGGCACATCATGGCTCCGGTGATGGAGCGCATGTACGACGCCGGGCAGGTG
GCCTACGCGGAGGTGGCGTCGGGCTCCGGCGCGGAGATGCTCTCCGCCGCGAGCCGCGTGTCGGAGCCGCTGCGCGCCTT
CCTGATCAAGCACGGGAGCGCTGAGGAGCGCGCGCGCTTCGTGGACCTGGCGCGCGAGCTACGTCCGGTGGAGGAGATGG
ACGCGGTGCGGGAGACGGACCTCTTCATCGTCATTCCTGCCTTCGTCATCACCGAGTTGAAGGAAGCCTTCCAGATTGGC
TTCCTCGTCTTCCTCCCGTTCCTCGTGCTGGACATGGTGATTGCCAACGTGCTGCTCGCGCTGGGCATGCAGACGCTGTC
ACCCAGCCAGGTGAGTCTGCCCTTCAAGATTCTCCTCTTCGTCGCCGTGGATGGTTGGTCGCTGCTCGCGCGGGGCCTCA
TCCTCGGCTACCGGTGA

Upstream 100 bases:

>100_bases
CGATTCGGGGCCGGCGGGAGGGGCCATGAGCCACGGCTTGCTGGGAGTGCTCCTGCTGGTTCCCGCCGTGGCCGCCGCGG
CGGAGAACTCACTGGCGCGG

Downstream 100 bases:

>100_bases
CGCCATGACCCAGGACGTTTTCCTCACCCTGGGACGCGAGGCCCTGCTGTTGATGGTGATGGCGTCGCTGCCACCCATTG
GCGCGAGCCTGGTGGTGGGG

Product: type III secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSYAGSPLSMMGMLAVMSLLPFAVLMLTSFSKIAVVLSLARSAMGTQQAPPTIVLTGLAAVLTGHIMAPVMERMYDAGQV
AYAEVASGSGAEMLSAASRVSEPLRAFLIKHGSAEERARFVDLARELRPVEEMDAVRETDLFIVIPAFVITELKEAFQIG
FLVFLPFLVLDMVIANVLLALGMQTLSPSQVSLPFKILLFVAVDGWSLLARGLILGYR

Sequences:

>Translated_218_residues
MSYAGSPLSMMGMLAVMSLLPFAVLMLTSFSKIAVVLSLARSAMGTQQAPPTIVLTGLAAVLTGHIMAPVMERMYDAGQV
AYAEVASGSGAEMLSAASRVSEPLRAFLIKHGSAEERARFVDLARELRPVEEMDAVRETDLFIVIPAFVITELKEAFQIG
FLVFLPFLVLDMVIANVLLALGMQTLSPSQVSLPFKILLFVAVDGWSLLARGLILGYR
>Mature_217_residues
SYAGSPLSMMGMLAVMSLLPFAVLMLTSFSKIAVVLSLARSAMGTQQAPPTIVLTGLAAVLTGHIMAPVMERMYDAGQVA
YAEVASGSGAEMLSAASRVSEPLRAFLIKHGSAEERARFVDLARELRPVEEMDAVRETDLFIVIPAFVITELKEAFQIGF
LVFLPFLVLDMVIANVLLALGMQTLSPSQVSLPFKILLFVAVDGWSLLARGLILGYR

Specific function: Important for pathogenicity [H]

COG id: COG4790

COG function: function code U; Type III secretory pathway, component EscR

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliP/mopC/spaP family [H]

Homologues:

Organism=Escherichia coli, GI1788259, Length=208, Percent_Identity=42.3076923076923, Blast_Score=153, Evalue=1e-38,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005838
- InterPro:   IPR005773 [H]

Pfam domain/function: PF00813 FliP [H]

EC number: NA

Molecular weight: Translated: 23481; Mature: 23350

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS01060 FLIP_1 ; PS01061 FLIP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYAGSPLSMMGMLAVMSLLPFAVLMLTSFSKIAVVLSLARSAMGTQQAPPTIVLTGLAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VLTGHIMAPVMERMYDAGQVAYAEVASGSGAEMLSAASRVSEPLRAFLIKHGSAEERARF
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VDLARELRPVEEMDAVRETDLFIVIPAFVITELKEAFQIGFLVFLPFLVLDMVIANVLLA
HHHHHHHCCHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMQTLSPSQVSLPFKILLFVAVDGWSLLARGLILGYR
HHHHHCCCCHHCCHHHHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SYAGSPLSMMGMLAVMSLLPFAVLMLTSFSKIAVVLSLARSAMGTQQAPPTIVLTGLAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
VLTGHIMAPVMERMYDAGQVAYAEVASGSGAEMLSAASRVSEPLRAFLIKHGSAEERARF
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VDLARELRPVEEMDAVRETDLFIVIPAFVITELKEAFQIGFLVFLPFLVLDMVIANVLLA
HHHHHHHCCHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMQTLSPSQVSLPFKILLFVAVDGWSLLARGLILGYR
HHHHHCCCCHHCCHHHHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1312532 [H]