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The map label for this gene is cinA [C]

Identifier: 108757479

GI number: 108757479

Start: 3996591

End: 3997331

Strand: Direct

Name: cinA [C]

Synonym: MXAN_3437

Alternate gene names: 108757479

Gene position: 3996591-3997331 (Clockwise)

Preceding gene: 108758469

Following gene: 108762992

Centisome position: 43.73

GC content: 69.77

Gene sequence:

>741_bases
ATGGAGCGGACCGGCGCAGCGGCAGTCATCATCGGCAACGAGGTCTTGACGGCGAAGGTCCATGACCTGAACGGGCCGCA
CCTCATCAAGCGCCTGCGCGAGGTGGGCATCCCGCTGCACTCGGTGGAGACGGTCCTCGACGACGTGGACGCCATCGTGG
ACGCGGTGGCCCGGGCCCGGCGCAAGGCGCGGTACGTCTTCACCAGCGGCGGCATCGGCCCCACCCATGACGACGTCACC
GTGCGCGCGGTGGCCCTGGCCATGGGACGGAACGTGGTTCGGCTGCAGGAGATGCTGGACCTCATCATGTCCCGTGCCAC
CGAGGAGCGGCCGGTGACGGCGGAAGGGCTGCGGCTCGCCGATGCCCCAGAGGGCGCCGTGCTGCTTCCCCAGGCCGACA
TGTGGTTCCCCGTCCTCACGGTGGATGACATCTTCCTGCTGCCCGGTGTGCCGCAGTTGTTCAGGATGCAGTTGGAGACC
GTGCTCGCGCGGCTGAGCGGGTCGCCCGTGGCCGTGAGCTGCCTCTACCTCCGGCTGGGCGAAAGCGACATCGCCGCCGT
GCTGGACCGCGTGGCGCTCGACATGCCGCACGTAGCCATCGGCTCCTACCCGGAGTTCGACACGGACAAGGACTACCGGG
TGAAGGTGACGGTGGAGTCCGCCCAGCGCGGGCCCGTGGATGACGCCCTGACGCGCATCCTCACGGGCCTGCCGGAAGGC
GCGGTGGTGCGGCGGGAGTAG

Upstream 100 bases:

>100_bases
CGGGCCACTTCTCCGCGAAGAACGTCCGCTGGCTGGAGTCGGTGGGGGTCGAGCCGTACATCACCATCTCCGGCCGGATT
CGACTAGAATCCCACCCCTT

Downstream 100 bases:

>100_bases
GGCTCCCGCCGCGTTCCGAAAGCGCCTACAGCCCCAGTCCCAGCCGCTGGCGCAGCCGGAAGAAGTCGTCCGTGAAGGTC
CACGCCAGAATCGTGCGCAG

Product: molybdopterin-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MERTGAAAVIIGNEVLTAKVHDLNGPHLIKRLREVGIPLHSVETVLDDVDAIVDAVARARRKARYVFTSGGIGPTHDDVT
VRAVALAMGRNVVRLQEMLDLIMSRATEERPVTAEGLRLADAPEGAVLLPQADMWFPVLTVDDIFLLPGVPQLFRMQLET
VLARLSGSPVAVSCLYLRLGESDIAAVLDRVALDMPHVAIGSYPEFDTDKDYRVKVTVESAQRGPVDDALTRILTGLPEG
AVVRRE

Sequences:

>Translated_246_residues
MERTGAAAVIIGNEVLTAKVHDLNGPHLIKRLREVGIPLHSVETVLDDVDAIVDAVARARRKARYVFTSGGIGPTHDDVT
VRAVALAMGRNVVRLQEMLDLIMSRATEERPVTAEGLRLADAPEGAVLLPQADMWFPVLTVDDIFLLPGVPQLFRMQLET
VLARLSGSPVAVSCLYLRLGESDIAAVLDRVALDMPHVAIGSYPEFDTDKDYRVKVTVESAQRGPVDDALTRILTGLPEG
AVVRRE
>Mature_246_residues
MERTGAAAVIIGNEVLTAKVHDLNGPHLIKRLREVGIPLHSVETVLDDVDAIVDAVARARRKARYVFTSGGIGPTHDDVT
VRAVALAMGRNVVRLQEMLDLIMSRATEERPVTAEGLRLADAPEGAVLLPQADMWFPVLTVDDIFLLPGVPQLFRMQLET
VLARLSGSPVAVSCLYLRLGESDIAAVLDRVALDMPHVAIGSYPEFDTDKDYRVKVTVESAQRGPVDDALTRILTGLPEG
AVVRRE

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family [H]

Homologues:

Organism=Homo sapiens, GI41872403, Length=244, Percent_Identity=30.327868852459, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI296434309, Length=244, Percent_Identity=30.327868852459, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI41872389, Length=244, Percent_Identity=30.327868852459, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI296434312, Length=232, Percent_Identity=29.7413793103448, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1788583, Length=203, Percent_Identity=30.5418719211823, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71993966, Length=258, Percent_Identity=26.7441860465116, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71993974, Length=258, Percent_Identity=26.7441860465116, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323832, Length=266, Percent_Identity=28.9473684210526, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR001453
- InterPro:   IPR023055 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 26745; Mature: 26745

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTGAAAVIIGNEVLTAKVHDLNGPHLIKRLREVGIPLHSVETVLDDVDAIVDAVARAR
CCCCCCEEEEECCEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RKARYVFTSGGIGPTHDDVTVRAVALAMGRNVVRLQEMLDLIMSRATEERPVTAEGLRLA
HHHEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
DAPEGAVLLPQADMWFPVLTVDDIFLLPGVPQLFRMQLETVLARLSGSPVAVSCLYLRLG
CCCCCCEEECCCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEHCC
ESDIAAVLDRVALDMPHVAIGSYPEFDTDKDYRVKVTVESAQRGPVDDALTRILTGLPEG
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCC
AVVRRE
CEEECC
>Mature Secondary Structure
MERTGAAAVIIGNEVLTAKVHDLNGPHLIKRLREVGIPLHSVETVLDDVDAIVDAVARAR
CCCCCCEEEEECCEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RKARYVFTSGGIGPTHDDVTVRAVALAMGRNVVRLQEMLDLIMSRATEERPVTAEGLRLA
HHHEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
DAPEGAVLLPQADMWFPVLTVDDIFLLPGVPQLFRMQLETVLARLSGSPVAVSCLYLRLG
CCCCCCEEECCCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEHCC
ESDIAAVLDRVALDMPHVAIGSYPEFDTDKDYRVKVTVESAQRGPVDDALTRILTGLPEG
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCC
AVVRRE
CEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]