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The map label for this gene is cysC

Identifier: 108757391

GI number: 108757391

Start: 4068053

End: 4068610

Strand: Direct

Name: cysC

Synonym: MXAN_3487

Alternate gene names: 108757391

Gene position: 4068053-4068610 (Clockwise)

Preceding gene: 108759439

Following gene: 108758985

Centisome position: 44.51

GC content: 70.07

Gene sequence:

>558_bases
ATGGGGCGTTCCGCGGGCTTCATACTCTGGCTGACAGGTCTGTCAGGTGCGGGCAAGAGCACCTTGTCCCGTGCACTGCG
TGCGCACCTGGCCTCGTCGATGCCCGTGGAGGTGCTGGACGGGGATGAGGTGCGCACCTGGCTGTCCCGCGGGCTGGGCT
TCACCCGCGAGGACCGCGAGGAGAACGTGCGCCGCATCGGTCATGTGGCCCGGCTGCTGGCGAAGCACGGGGTGGGCGTC
ATCGCCGCGGCCATTTCGCCCTATGCGAGCTCGCGCGCCGAGGTGCGCCGGCTGGCCGAGGAAGCGGGCATCCCCTTCGT
GGAAATCTATGTCCAGGCGCCTCTGGACGTGCTCATCGCCCGGGACGTGAAGGGGCTCTACAAGAAGGCGCTGGCCGGCG
AGCTGGCGCACTTCACCGGCGTGTCGGACCCCTATGAGGCGCCTGACGCGCCCGACGTCACCGTCCACTCGGATGTGGAC
ACCGTGGAGGCGGGCCTGTGGCGCGTCTTGGAGACGCTGCGAAAGCGGGGCCTGCTCGACGCCGCCGCGGCGGCGTGA

Upstream 100 bases:

>100_bases
AAGGCTCTGTCGCATGGCCACGGAAAACGGGTCAAGTCCCGGAGGCCGCGTGGCGTGTTAGCGTTTCGGGGACGCGCAGG
GGCGTCGTTCTGGAGTCACA

Downstream 100 bases:

>100_bases
AGCGCGTCCCCGAGGTGGCGGAACGTCCGCGCACCTCGGGGGAACGGAGGCGCGGACTCAAGCGAGGATGCGCTCCATCT
TCACGTAGGGGCGCTCGGCC

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MGRSAGFILWLTGLSGAGKSTLSRALRAHLASSMPVEVLDGDEVRTWLSRGLGFTREDREENVRRIGHVARLLAKHGVGV
IAAAISPYASSRAEVRRLAEEAGIPFVEIYVQAPLDVLIARDVKGLYKKALAGELAHFTGVSDPYEAPDAPDVTVHSDVD
TVEAGLWRVLETLRKRGLLDAAAAA

Sequences:

>Translated_185_residues
MGRSAGFILWLTGLSGAGKSTLSRALRAHLASSMPVEVLDGDEVRTWLSRGLGFTREDREENVRRIGHVARLLAKHGVGV
IAAAISPYASSRAEVRRLAEEAGIPFVEIYVQAPLDVLIARDVKGLYKKALAGELAHFTGVSDPYEAPDAPDVTVHSDVD
TVEAGLWRVLETLRKRGLLDAAAAA
>Mature_184_residues
GRSAGFILWLTGLSGAGKSTLSRALRAHLASSMPVEVLDGDEVRTWLSRGLGFTREDREENVRRIGHVARLLAKHGVGVI
AAAISPYASSRAEVRRLAEEAGIPFVEIYVQAPLDVLIARDVKGLYKKALAGELAHFTGVSDPYEAPDAPDVTVHSDVDT
VEAGLWRVLETLRKRGLLDAAAAA

Specific function: Catalyzes the synthesis of activated sulfate

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family

Homologues:

Organism=Homo sapiens, GI34447231, Length=175, Percent_Identity=48, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI62912492, Length=175, Percent_Identity=48, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI46094058, Length=180, Percent_Identity=47.7777777777778, Blast_Score=169, Evalue=1e-42,
Organism=Escherichia coli, GI1789107, Length=175, Percent_Identity=42.8571428571429, Blast_Score=134, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17542422, Length=183, Percent_Identity=42.0765027322404, Blast_Score=152, Evalue=7e-38,
Organism=Saccharomyces cerevisiae, GI6322852, Length=174, Percent_Identity=44.8275862068966, Blast_Score=150, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24667032, Length=175, Percent_Identity=45.7142857142857, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667028, Length=175, Percent_Identity=45.7142857142857, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667036, Length=175, Percent_Identity=45.7142857142857, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667040, Length=175, Percent_Identity=45.7142857142857, Blast_Score=161, Evalue=2e-40,
Organism=Drosophila melanogaster, GI116007838, Length=175, Percent_Identity=45.7142857142857, Blast_Score=161, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667044, Length=175, Percent_Identity=45.7142857142857, Blast_Score=161, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSC_MYXXD (Q1D6P1)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_631682.1
- ProteinModelPortal:   Q1D6P1
- SMR:   Q1D6P1
- STRING:   Q1D6P1
- GeneID:   4105361
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_3487
- TIGR:   MXAN_3487
- eggNOG:   COG0529
- HOGENOM:   HBG309946
- OMA:   ITITAFV
- PhylomeDB:   Q1D6P1
- ProtClustDB:   CLSK2778026
- BioCyc:   MXAN246197:MXAN_3487-MONOMER
- HAMAP:   MF_00065
- InterPro:   IPR002891
- TIGRFAMs:   TIGR00455

Pfam domain/function: PF01583 APS_kinase

EC number: =2.7.1.25

Molecular weight: Translated: 19866; Mature: 19735

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: ACT_SITE 86-86

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRSAGFILWLTGLSGAGKSTLSRALRAHLASSMPVEVLDGDEVRTWLSRGLGFTREDRE
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCHHHHH
ENVRRIGHVARLLAKHGVGVIAAAISPYASSRAEVRRLAEEAGIPFVEIYVQAPLDVLIA
HHHHHHHHHHHHHHHCCCHHHHHHHCHHHCHHHHHHHHHHHHCCCEEEEEECCCHHHHHH
RDVKGLYKKALAGELAHFTGVSDPYEAPDAPDVTVHSDVDTVEAGLWRVLETLRKRGLLD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCHH
AAAAA
HHHCC
>Mature Secondary Structure 
GRSAGFILWLTGLSGAGKSTLSRALRAHLASSMPVEVLDGDEVRTWLSRGLGFTREDRE
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHCCCCCHHHHH
ENVRRIGHVARLLAKHGVGVIAAAISPYASSRAEVRRLAEEAGIPFVEIYVQAPLDVLIA
HHHHHHHHHHHHHHHCCCHHHHHHHCHHHCHHHHHHHHHHHHCCCEEEEEECCCHHHHHH
RDVKGLYKKALAGELAHFTGVSDPYEAPDAPDVTVHSDVDTVEAGLWRVLETLRKRGLLD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCHH
AAAAA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA