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The map label for this gene is pkn1 [H]

Identifier: 108757085

GI number: 108757085

Start: 4371214

End: 4372218

Strand: Reverse

Name: pkn1 [H]

Synonym: MXAN_3662

Alternate gene names: 108757085

Gene position: 4372218-4371214 (Counterclockwise)

Preceding gene: 108762745

Following gene: 108759706

Centisome position: 47.84

GC content: 68.86

Gene sequence:

>1005_bases
ATGAGCATCGACGTCATCGACGAAGTCCCGGCCCAGGGCGGCCGGCCCCTCGAGGACGGCGCGGGGCAGGAAGCCCGCTC
GCTGCCGGGCATGGTCTACATCCCCGGTGGGACGTTCTGGATGGGCTCGGACCATCACTATCCGGAGGAGCGGCCGACGC
ACCAGGTGACGGTGACGGACTTCTGGATGGACAGCCAACTGGTGACGAACGCGGACTTCGCGCGCTTCGTGGAGGCCACC
GGCTACGTCACCGTGGCCGAGCGCCCCTTGAACCCCGACGACTTTCCCGGCGCGAATCCAGCGCTGCTCGTCCCGGGCTC
GCTCGTCTTCAAGAAGACGCTCGCTCGCGTGGACCTGCGCGACCTGACGCAGTGGTGGTTCTATACGGCGGGCGCCTGCT
GGAAGTACCCCGAAGGCGCGGGCAGCACCTGGCAGGGGCGCGAACAATACCCGGTGGTTCACGTCTGCTTCGAGGACGCG
CTCGCCTATGCGCTCTGGGCGGGCAAGACGCTGCCCACCGAGGCGGAATGGGAGTACGCCGCGCGCGGAGGCCTGGACCG
GAAGGTCTACGTCTGGGGCGACGAGTTCGCGCCGGGTGGCAAGCTGATGGCCAACACCTGGCAGGGGGAGTTCCCCTGGC
AGAACCTGAACACGGATGGCTTCGAGGGCACGTCCCCGGTGGGCAACTTCCCACCGAACGCCTACGGCCTCTTCGACATG
GCCGGCAACGTGTGGGAGTGGACCTCGGACTGGTACCAGGAGCGGCACGAGGGGAATGGCGGAAAGCCCTGCTGCATCCC
CGTCAATCCACGGGGACCGGCCACGTCGGATCGCAGCCTGGACCCGTGCCTGCCGAAGGTGAAGATTCCCCGGCGCGTCC
TCAAGGGCGGCAGCCACCTGTGCGCGCCGAACTACTGCCTGCGCTACCGCCCGGCGGCGCGCTCACCGCAGGCCGTGGAC
AGCGGCACGTCGCACATCGGGTTCCGCTGCGTCGTCCGCCCCTGA

Upstream 100 bases:

>100_bases
CTACCCCTGAGGGCCGGATTGTTCCGTGCCGCGTGGCCCCCCACGTTTGCTACCGGGGCACGGCGCGCCCCTCCGTTCTC
GCAGGGAAGGAGGCACGCAC

Downstream 100 bases:

>100_bases
GCCGCAAGCTGGCATTTCCAGAGAAGGTCTTGCGACGTTGTCGCGGCGCTTCCACTCGCCGCGACTCCATCCCTATCGTG
TCACCCGCCTCCAACGACAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSIDVIDEVPAQGGRPLEDGAGQEARSLPGMVYIPGGTFWMGSDHHYPEERPTHQVTVTDFWMDSQLVTNADFARFVEAT
GYVTVAERPLNPDDFPGANPALLVPGSLVFKKTLARVDLRDLTQWWFYTAGACWKYPEGAGSTWQGREQYPVVHVCFEDA
LAYALWAGKTLPTEAEWEYAARGGLDRKVYVWGDEFAPGGKLMANTWQGEFPWQNLNTDGFEGTSPVGNFPPNAYGLFDM
AGNVWEWTSDWYQERHEGNGGKPCCIPVNPRGPATSDRSLDPCLPKVKIPRRVLKGGSHLCAPNYCLRYRPAARSPQAVD
SGTSHIGFRCVVRP

Sequences:

>Translated_334_residues
MSIDVIDEVPAQGGRPLEDGAGQEARSLPGMVYIPGGTFWMGSDHHYPEERPTHQVTVTDFWMDSQLVTNADFARFVEAT
GYVTVAERPLNPDDFPGANPALLVPGSLVFKKTLARVDLRDLTQWWFYTAGACWKYPEGAGSTWQGREQYPVVHVCFEDA
LAYALWAGKTLPTEAEWEYAARGGLDRKVYVWGDEFAPGGKLMANTWQGEFPWQNLNTDGFEGTSPVGNFPPNAYGLFDM
AGNVWEWTSDWYQERHEGNGGKPCCIPVNPRGPATSDRSLDPCLPKVKIPRRVLKGGSHLCAPNYCLRYRPAARSPQAVD
SGTSHIGFRCVVRP
>Mature_333_residues
SIDVIDEVPAQGGRPLEDGAGQEARSLPGMVYIPGGTFWMGSDHHYPEERPTHQVTVTDFWMDSQLVTNADFARFVEATG
YVTVAERPLNPDDFPGANPALLVPGSLVFKKTLARVDLRDLTQWWFYTAGACWKYPEGAGSTWQGREQYPVVHVCFEDAL
AYALWAGKTLPTEAEWEYAARGGLDRKVYVWGDEFAPGGKLMANTWQGEFPWQNLNTDGFEGTSPVGNFPPNAYGLFDMA
GNVWEWTSDWYQERHEGNGGKPCCIPVNPRGPATSDRSLDPCLPKVKIPRRVLKGGSHLCAPNYCLRYRPAARSPQAVDS
GTSHIGFRCVVRP

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=320, Percent_Identity=41.5625, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI257470975, Length=315, Percent_Identity=40.9523809523809, Blast_Score=228, Evalue=7e-60,
Organism=Homo sapiens, GI257470977, Length=320, Percent_Identity=38.75, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI194248088, Length=315, Percent_Identity=35.5555555555556, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI194248087, Length=309, Percent_Identity=34.9514563106796, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI226437577, Length=235, Percent_Identity=37.0212765957447, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI194248090, Length=217, Percent_Identity=40.0921658986175, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI20130397, Length=331, Percent_Identity=39.8791540785499, Blast_Score=217, Evalue=8e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 37077; Mature: 36946

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDVIDEVPAQGGRPLEDGAGQEARSLPGMVYIPGGTFWMGSDHHYPEERPTHQVTVTD
CCCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEECCCEEEECCCCCCCCCCCCCEEEEEE
FWMDSQLVTNADFARFVEATGYVTVAERPLNPDDFPGANPALLVPGSLVFKKTLARVDLR
EECCCHHHCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCHH
DLTQWWFYTAGACWKYPEGAGSTWQGREQYPVVHVCFEDALAYALWAGKTLPTEAEWEYA
HHHHHHHHHCCCEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCHHH
ARGGLDRKVYVWGDEFAPGGKLMANTWQGEFPWQNLNTDGFEGTSPVGNFPPNAYGLFDM
HCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHC
AGNVWEWTSDWYQERHEGNGGKPCCIPVNPRGPATSDRSLDPCLPKVKIPRRVLKGGSHL
CCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCE
CAPNYCLRYRPAARSPQAVDSGTSHIGFRCVVRP
ECCCCEEEECCCCCCCCHHCCCCCCCEEEEEECC
>Mature Secondary Structure 
SIDVIDEVPAQGGRPLEDGAGQEARSLPGMVYIPGGTFWMGSDHHYPEERPTHQVTVTD
CCCCCCCCCCCCCCCCCCCCCCHHHHCCCEEEECCCEEEECCCCCCCCCCCCCEEEEEE
FWMDSQLVTNADFARFVEATGYVTVAERPLNPDDFPGANPALLVPGSLVFKKTLARVDLR
EECCCHHHCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCHH
DLTQWWFYTAGACWKYPEGAGSTWQGREQYPVVHVCFEDALAYALWAGKTLPTEAEWEYA
HHHHHHHHHCCCEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCHHH
ARGGLDRKVYVWGDEFAPGGKLMANTWQGEFPWQNLNTDGFEGTSPVGNFPPNAYGLFDM
HCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHC
AGNVWEWTSDWYQERHEGNGGKPCCIPVNPRGPATSDRSLDPCLPKVKIPRRVLKGGSHL
CCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCE
CAPNYCLRYRPAARSPQAVDSGTSHIGFRCVVRP
ECCCCEEEECCCCCCCCHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]