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The map label for this gene is frr [H]

Identifier: 108563625

GI number: 108563625

Start: 1263982

End: 1264539

Strand: Direct

Name: frr [H]

Synonym: HPAG1_1200

Alternate gene names: 108563625

Gene position: 1263982-1264539 (Clockwise)

Preceding gene: 108563624

Following gene: 108563626

Centisome position: 79.18

GC content: 40.32

Gene sequence:

>558_bases
ATGTTACAAGCCATTTATAACGAAACCAAAGATCTAATGCAAAAAAGTGTTCAAGCTTTAAACAGGGATTTTTCCACTCT
AAGGAGCGCGAAAGTTTCAGTCAATATTTTAGATCACATCAAAGTGGATTATTACGGCACGCCCACCGCATTAAATCAAG
TCGGATCCGTGATGAGCTTGGATGCGACCACTCTTCAAATCAGCCCATGGGAAAAAAACCTGCTCAAGGAAATTGAAAGA
TCCATTCAAGAAGCCAATATTGGCGTCAATCCTAATAACGACGGCGAAACGATCAAGCTTTTTTTCCCGCCCATGACAAC
CGAGCAAAGGAAACTCATCGCAAAAGACGCCAAAGCGATGGGCGAAAAGGCCAAAGTGGCTGTAAGGAATATCCGCCAAG
ACGCTAACAACAAGGTAAAAAAATTAGAAAAAGACAAAGAAATCAGCGAAGATGAAAGCAAAAAAGCCCAAGAACAGATC
CAAAAAATCACCGATGAAGCCATTAAAAAAATTGATGAAAGCGTGAAAAACAAAGAAGACGCGATTTTAAAGGTCTAA

Upstream 100 bases:

>100_bases
AAACCAAAGAGAGTGCAAAAACGCCCCCAACCACCCACCAAAAGCCTAAAACGCATGCGACAACCAACGCCCATACCAAC
CAAAAAAAGGATGAAAAATA

Downstream 100 bases:

>100_bases
AGCATGGATATTAAGGCATGTTATCAAAACGCTCAAGCGCTATTAGAGGGGCATTTCTTGCTCAGCAGCGGGTTTCATTC
CAATTATTATTTGCAATCCG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLQAIYNETKDLMQKSVQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSLDATTLQISPWEKNLLKEIER
SIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNIRQDANNKVKKLEKDKEISEDESKKAQEQI
QKITDEAIKKIDESVKNKEDAILKV

Sequences:

>Translated_185_residues
MLQAIYNETKDLMQKSVQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSLDATTLQISPWEKNLLKEIER
SIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNIRQDANNKVKKLEKDKEISEDESKKAQEQI
QKITDEAIKKIDESVKNKEDAILKV
>Mature_185_residues
MLQAIYNETKDLMQKSVQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSLDATTLQISPWEKNLLKEIER
SIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNIRQDANNKVKKLEKDKEISEDESKKAQEQI
QKITDEAIKKIDESVKNKEDAILKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=41.8478260869565, Blast_Score=160, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24661488, Length=172, Percent_Identity=25.5813953488372, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20915; Mature: 20915

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQAIYNETKDLMQKSVQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHEEECCCCCCHHHHHHCHHHCC
DATTLQISPWEKNLLKEIERSIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAM
CCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
GEKAKVAVRNIRQDANNKVKKLEKDKEISEDESKKAQEQIQKITDEAIKKIDESVKNKED
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AILKV
CEECC
>Mature Secondary Structure
MLQAIYNETKDLMQKSVQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHEEECCCCCCHHHHHHCHHHCC
DATTLQISPWEKNLLKEIERSIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAM
CCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
GEKAKVAVRNIRQDANNKVKKLEKDKEISEDESKKAQEQIQKITDEAIKKIDESVKNKED
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AILKV
CEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA