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The map label for this gene is murG [H]

Identifier: 108563519

GI number: 108563519

Start: 1148750

End: 1149811

Strand: Direct

Name: murG [H]

Synonym: HPAG1_1094

Alternate gene names: 108563519

Gene position: 1148750-1149811 (Clockwise)

Preceding gene: 108563518

Following gene: 108563520

Centisome position: 71.96

GC content: 41.34

Gene sequence:

>1062_bases
ATGAAATTCGCTCTTACAGGGGGAGGCACAGGGGGGCATCTCTCTATCGCTAAAGCCTTAGCCATAGAATTAGAAAAGCA
AGGCATAGAGGCTATTTATCTAGGTTCAACCTATGGGCAAGATAAAGAATGGTTTGAAAATAGCCCCCTATTTAGCGAAC
GCTATTTTTTCAACACGCAAGGCGTGGTCAATAAAAGTTTTTTTAAAAAAATAGGCTCTTTATTCTTGCAAGCTAAAGCC
GCTTTTAAGGCTAAAGAAATCCTAAAAAAACACCAGATCACGCACACCATTAGCGTGGGAGGGTTTAGCGCAGGGCCGGC
AAGTTTTGCAAGCTTACTCAATAAAATACCCCTTTATATCCATGAGCAAAATGCGATTAAAGGCTCTCTTAATCGCTACC
TTTCCCCTAAAGCTAAGGCGGTGTTTTCAAGCTATGCGTTTAAAGATAAGGGCCATCATGTTTTAACCTCCTATCCCGTG
CAAAACGCTTTTTTTGATTTTGCTAGGACTCGAACTGAAATCAAGCACATTTTATTTTTAGGCGGTTCGCAAGGGGCAAA
AGCGATCAATGAATTCGCTTTATTAAACGCTCCCAAACTCACCAAACAAGGGATTAAAATCACGCACATTTGCGGCCCCA
ATTCTTATGAACAAGTGCGTTTTTTTTACCAGGAATTGGGGCTGTTGGACAAGATAGAATTGTTCGCTTTCCACAATAAT
ATCACAGAAGTCATGCACAGGGCGGATTTGTGTGTGAGCCGAGCGGGTGCTAGCAGCGTGTGGGAATTGTGCGCCAATGG
CTTACCCACGATTTTTATCCCCTACCCTTTTGCGAGCAATAACCACCAGTATTACAATGTCTTAGAATTTGAAAAAGAAA
ACCTATGCTATGTTGCACCTCAAAATGAATTATTGCCTAAAAAACTCTTTGAAGTCATTAGAAAGCTCAACCAAAAAGAT
GATCAAGGCAATAAAAACCTAACCGCTATCAGCAACCAATTGCAGCAAAAAATCGCTAAAGACGGCGCAAAAACCATCAT
TGAAACGATTTTGAGCGCCTAA

Upstream 100 bases:

>100_bases
AAGTGGCGCTTTCTATGATGGATTATCCGGATTTTGGCTTTAGAGATCCTTTAAAAAGCTTTGTGGTTAAAGAAAGAGAA
CGAGCTTAAGGGTTTTTAGC

Downstream 100 bases:

>100_bases
AATAGCCCATTTTAATCAACAATTAAGCGACTAACCATTAAACTTAAGCGATAAATAAGATAAAATTTAGGATAGCTCAA
ATCTTTTAAAAAGAAAAGGA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQGVVNKSFFKKIGSLFLQAKA
AFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYIHEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGHHVLTSYPV
QNAFFDFARTRTEIKHILFLGGSQGAKAINEFALLNAPKLTKQGIKITHICGPNSYEQVRFFYQELGLLDKIELFAFHNN
ITEVMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVAPQNELLPKKLFEVIRKLNQKD
DQGNKNLTAISNQLQQKIAKDGAKTIIETILSA

Sequences:

>Translated_353_residues
MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQGVVNKSFFKKIGSLFLQAKA
AFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYIHEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGHHVLTSYPV
QNAFFDFARTRTEIKHILFLGGSQGAKAINEFALLNAPKLTKQGIKITHICGPNSYEQVRFFYQELGLLDKIELFAFHNN
ITEVMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVAPQNELLPKKLFEVIRKLNQKD
DQGNKNLTAISNQLQQKIAKDGAKTIIETILSA
>Mature_353_residues
MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQGVVNKSFFKKIGSLFLQAKA
AFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYIHEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGHHVLTSYPV
QNAFFDFARTRTEIKHILFLGGSQGAKAINEFALLNAPKLTKQGIKITHICGPNSYEQVRFFYQELGLLDKIELFAFHNN
ITEVMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVAPQNELLPKKLFEVIRKLNQKD
DQGNKNLTAISNQLQQKIAKDGAKTIIETILSA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=309, Percent_Identity=27.1844660194175, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 39426; Mature: 39426

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQ
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHCCCCCCCCCEEECCC
GVVNKSFFKKIGSLFLQAKAAFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCEEE
HEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGHHVLTSYPVQNAFFDFARTRTEIKHILFL
ECCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHEEEEE
GGSQGAKAINEFALLNAPKLTKQGIKITHICGPNSYEQVRFFYQELGLLDKIELFAFHNN
CCCCCHHHHHHHHHCCCCCHHHCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHH
ITEVMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVAP
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCEEEECC
QNELLPKKLFEVIRKLNQKDDQGNKNLTAISNQLQQKIAKDGAKTIIETILSA
CCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQ
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHCCCCCCCCCEEECCC
GVVNKSFFKKIGSLFLQAKAAFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCEEE
HEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGHHVLTSYPVQNAFFDFARTRTEIKHILFL
ECCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHEEEEE
GGSQGAKAINEFALLNAPKLTKQGIKITHICGPNSYEQVRFFYQELGLLDKIELFAFHNN
CCCCCHHHHHHHHHCCCCCHHHCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHH
ITEVMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVAP
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCEEEECC
QNELLPKKLFEVIRKLNQKDDQGNKNLTAISNQLQQKIAKDGAKTIIETILSA
CCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA