| Definition | Helicobacter pylori HPAG1 chromosome, complete genome. |
|---|---|
| Accession | NC_008086 |
| Length | 1,596,366 |
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The map label for this gene is acnB [H]
Identifier: 108563189
GI number: 108563189
Start: 799898
End: 802459
Strand: Direct
Name: acnB [H]
Synonym: HPAG1_0764
Alternate gene names: 108563189
Gene position: 799898-802459 (Clockwise)
Preceding gene: 108563180
Following gene: 108563190
Centisome position: 50.11
GC content: 45.55
Gene sequence:
>2562_bases ATGATGAAAGATTTTTTAGAAGATTACAAAAAAAGCGTTTCAGAAAGAGAGAGCGAGGGTATCCCGCCACTCCCTTTAAA CGCTAAACAAGTGGAGTCTGTCGTTGAGATTTTAACAAAAGATCCCACAAACGCCGCTTTCGCTAAAGAATTACTCATTC ACAGAGTGAGCCCTGGGGTTGATGAAGGGGCGAAAGTGAAAGCGGAATTTTTAGCCAAATTGTCTCAAAAAAAACTAGAA TGCGCACACATTAGTGCTTTAGAAGCGACCACTCTTTTAGGCACGATGCTTGGGGGGTATAATGTAGAGCCTTTGATTAT GGGATTAGAAAGTCAAGACAAAAACATCGCTAAAGAGAGCGCAAAAGCGTTAAAAACCACTCTTTTAGTCTATGGATCGT TTGATAAAATCGCTGCAATGAGCCAAACTAACGCTTTGGCTAAAGAAGTGCTAGAGTCTTGGGCGAACGCCGAATGGTTT TTGAATAAAGAGCCTTTGAATGAATGCATTGAAGCGTGTGTGTTTAAGATTGATGGCGAAACCAATACCGATGATTTAAG CCCAGCGAGCGATGCTTTCACACGAAGCGATATTCCTTTACACGCCAAAGCCATGCTAAAAAACCGGATTGAAAATTACG AACAACGCATCAAAGCCATTAAAACTAAAGGCGTTCCTGTAGCGTATGTGGGCGATGTGGTCGGCACAGGAAGCTCTAGA AAAAGCGCGACGAACTCTATCATGTGGCATTTTGGTAAGGACATTCCTTTTGTGCCTAATAAAAGGAGTGGGGGCATTGT GATTGGGGGGGTGATCGCTCCGATTTTCTTTGCGACTTGTGAAGATAGCGGGGCGTTACCCATTGTGGCTGATGTTAAGG ACTTAAAAGAGGGCGATTTGATTAAAATCTATCCTTATAAAGGCGAAATCACGCTGAACGATAAAGTGGTTAGCACTTTT AAGCTAGAGCCTGAAACTTTGTTAGATGAAGTTAGGGCTTCTGGGCGTATCCCTTTAATCATTGGCAGGGGTTTGACGAA TAAAGCGCGTAAATTTTTAGGGCTAGGCGAATCGGAAGCGTTCAAAAAACCATCCGCTCCTAAAAGCGACGCTAAAGGCT ACACTTTAGCCCAAAAAATCGTAGGGCATGCTTGTGGGGTAAAAGGGATCTTGCCTGGTGCTTATTGTGAGCCAAAGGTT ACCACCGTGGGCAGTCAAGACACCACAGGGGCGATGACCAGAGATGAGGTTAAAGAATTAGCGAGTTTGAAATTTGATGC GCCTTTTGTGTTGCAGAGTTTTTGCCATACCGCCGCTTACCCAAAACCTAGCGATGTGAGTTTACATGCAACCTTGCCTA GCTTTATCACTCAAAGAGGGGGCGTGGCGTTGCATCCGGGCGATGGCGTGATCCATACATGGCTGAACCGCATGGGATTG CCTGACACTTTAGGCACAGGGGGGGATAGCCACACCCGTTTCCCTTTGGGCATTAGTTTCCCGGCAGGGAGTGGGCTAGT CGCTTTTGCAGCCGTTACAGGCACGATGCCATTGAACATGCCAGAATCCGTGTTAGTGCGTTTTAAAGGGGAAATGAATC CTGGGATCACCTTAAGGGATTTAGTGAATGCAATCCCTTATTATGCCATTAAAAAAGGGTTGCTCACGGTGGAGAAAAAG GGTAAAATCAATGTCTTTAACGGGCGTATTTTAGAAATTGAAGGCTTGCCTGATATTAAAATGGAGCAGGCTTTTGAACT AAGCGATGCGAGCGCTGAAAGGAGTGCGGCGGCTTGCGTGGTGCGTTTGAATAAAGAGCCGATGATTGAATACTTAAAAT CCAACATCAAGCTCATTGATGAGATGATTGCGAGCGGTTATGAAGATAAAGAGACTTTGAAAAAACGCAGAGATGCGATG CAAGCTTGGGTGGATAAGCCGGTATTGTTAGAGCCAGATAGTAACGCCCAATACGCCGCTGTCATTGAAATTGATGTGGC AGAAATCACTGAGCCTATTTTGGCATGCCCTAATGACCCTGATGATGTCGCCACTTTGAGCGAAGTTTTAGCGGATACGA CCGGCAAAAGACCGCACGCTATTGATGAAGTGTTTATTGGCTCTTGCATGACGAATATCGGGCATTTTAGAGCCTTTGGC GAAATCGTTAAAAACGCTCCTCCCAGTCAAGCACGCCTTTGGGTAGTGCCGCCCAGTAAAATGGACGAACAAGAGCTGAT TAATGAGGGCTATTATGCGATTTTTGGAGCTGCCGGGGCAAGGACTGAAGTCCCAGGCTGTAGCTTGTGCATGGGCAATC AAGCGAGGGTTAGGGATAATGCGGTCGTCTTTTCCACTTCCACACGGAATTTTGATAATCGCATGGGTAGAGGGGCTAAA GTGTATTTAGGCAGCGCGGAGCTTGGGGCGGCGTGCGCTTTACTAGGGAGAATCCCCACTAAAGAAGAATACATGAATTT AGTGAGCGAAAAGCTAGAGAGCCAAAAAGACAAGATCTATCGCTACATGAATTTTAACTTAATGGAGAATTTCAGGCTCT AG
Upstream 100 bases:
>100_bases AGCTAAAGTTTCTTACAACTTAACTAAAAGTAAAAAGAGTTTTGTTATCATGGGGCAAATGATTAGGGCATTAGCCAATA ATGCTATTTAAAAAGGAGAA
Downstream 100 bases:
>100_bases TTTTGTTTTCATTAAAAGGGAATGATCCCTTTTATTTGGCTATGGCTGAGTGTTGAGAGAGAATAAAAGAGGAAGCGGTG ATGAAAAAAGTCGTTGTGAG
Product: bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
Products: NA
Alternate protein names: Aconitase 2; 2-methylisocitrate dehydratase; Citrate hydro-lyase 2 [H]
Number of amino acids: Translated: 853; Mature: 853
Protein sequence:
>853_residues MMKDFLEDYKKSVSERESEGIPPLPLNAKQVESVVEILTKDPTNAAFAKELLIHRVSPGVDEGAKVKAEFLAKLSQKKLE CAHISALEATTLLGTMLGGYNVEPLIMGLESQDKNIAKESAKALKTTLLVYGSFDKIAAMSQTNALAKEVLESWANAEWF LNKEPLNECIEACVFKIDGETNTDDLSPASDAFTRSDIPLHAKAMLKNRIENYEQRIKAIKTKGVPVAYVGDVVGTGSSR KSATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVKDLKEGDLIKIYPYKGEITLNDKVVSTF KLEPETLLDEVRASGRIPLIIGRGLTNKARKFLGLGESEAFKKPSAPKSDAKGYTLAQKIVGHACGVKGILPGAYCEPKV TTVGSQDTTGAMTRDEVKELASLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPSFITQRGGVALHPGDGVIHTWLNRMGL PDTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLVRFKGEMNPGITLRDLVNAIPYYAIKKGLLTVEKK GKINVFNGRILEIEGLPDIKMEQAFELSDASAERSAAACVVRLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAM QAWVDKPVLLEPDSNAQYAAVIEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDEVFIGSCMTNIGHFRAFG EIVKNAPPSQARLWVVPPSKMDEQELINEGYYAIFGAAGARTEVPGCSLCMGNQARVRDNAVVFSTSTRNFDNRMGRGAK VYLGSAELGAACALLGRIPTKEEYMNLVSEKLESQKDKIYRYMNFNLMENFRL
Sequences:
>Translated_853_residues MMKDFLEDYKKSVSERESEGIPPLPLNAKQVESVVEILTKDPTNAAFAKELLIHRVSPGVDEGAKVKAEFLAKLSQKKLE CAHISALEATTLLGTMLGGYNVEPLIMGLESQDKNIAKESAKALKTTLLVYGSFDKIAAMSQTNALAKEVLESWANAEWF LNKEPLNECIEACVFKIDGETNTDDLSPASDAFTRSDIPLHAKAMLKNRIENYEQRIKAIKTKGVPVAYVGDVVGTGSSR KSATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVKDLKEGDLIKIYPYKGEITLNDKVVSTF KLEPETLLDEVRASGRIPLIIGRGLTNKARKFLGLGESEAFKKPSAPKSDAKGYTLAQKIVGHACGVKGILPGAYCEPKV TTVGSQDTTGAMTRDEVKELASLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPSFITQRGGVALHPGDGVIHTWLNRMGL PDTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLVRFKGEMNPGITLRDLVNAIPYYAIKKGLLTVEKK GKINVFNGRILEIEGLPDIKMEQAFELSDASAERSAAACVVRLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAM QAWVDKPVLLEPDSNAQYAAVIEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDEVFIGSCMTNIGHFRAFG EIVKNAPPSQARLWVVPPSKMDEQELINEGYYAIFGAAGARTEVPGCSLCMGNQARVRDNAVVFSTSTRNFDNRMGRGAK VYLGSAELGAACALLGRIPTKEEYMNLVSEKLESQKDKIYRYMNFNLMENFRL >Mature_853_residues MMKDFLEDYKKSVSERESEGIPPLPLNAKQVESVVEILTKDPTNAAFAKELLIHRVSPGVDEGAKVKAEFLAKLSQKKLE CAHISALEATTLLGTMLGGYNVEPLIMGLESQDKNIAKESAKALKTTLLVYGSFDKIAAMSQTNALAKEVLESWANAEWF LNKEPLNECIEACVFKIDGETNTDDLSPASDAFTRSDIPLHAKAMLKNRIENYEQRIKAIKTKGVPVAYVGDVVGTGSSR KSATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVKDLKEGDLIKIYPYKGEITLNDKVVSTF KLEPETLLDEVRASGRIPLIIGRGLTNKARKFLGLGESEAFKKPSAPKSDAKGYTLAQKIVGHACGVKGILPGAYCEPKV TTVGSQDTTGAMTRDEVKELASLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPSFITQRGGVALHPGDGVIHTWLNRMGL PDTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLVRFKGEMNPGITLRDLVNAIPYYAIKKGLLTVEKK GKINVFNGRILEIEGLPDIKMEQAFELSDASAERSAAACVVRLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAM QAWVDKPVLLEPDSNAQYAAVIEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDEVFIGSCMTNIGHFRAFG EIVKNAPPSQARLWVVPPSKMDEQELINEGYYAIFGAAGARTEVPGCSLCMGNQARVRDNAVVFSTSTRNFDNRMGRGAK VYLGSAELGAACALLGRIPTKEEYMNLVSEKLESQKDKIYRYMNFNLMENFRL
Specific function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate as well as the dehydration of 2-methylisocitrate to cis-2-methylaconitate [H]
COG id: COG1049
COG function: function code C; Aconitase B
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aconitase/IPM isomerase family [H]
Homologues:
Organism=Escherichia coli, GI2367097, Length=864, Percent_Identity=60.6481481481482, Blast_Score=1018, Evalue=0.0, Organism=Escherichia coli, GI1786259, Length=377, Percent_Identity=28.3819628647215, Blast_Score=96, Evalue=1e-20, Organism=Saccharomyces cerevisiae, GI6321429, Length=371, Percent_Identity=26.6846361185984, Blast_Score=69, Evalue=3e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015931 - InterPro: IPR015937 - InterPro: IPR001030 - InterPro: IPR015928 - InterPro: IPR015932 - InterPro: IPR018136 - InterPro: IPR004406 - InterPro: IPR015930 - InterPro: IPR015933 - InterPro: IPR015929 [H]
Pfam domain/function: PF00330 Aconitase; PF06434 Aconitase_2_N; PF11791 Aconitase_B_N [H]
EC number: =4.2.1.3; =4.2.1.99 [H]
Molecular weight: Translated: 92870; Mature: 92870
Theoretical pI: Translated: 6.28; Mature: 6.28
Prosite motif: PS00450 ACONITASE_1 ; PS01244 ACONITASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMKDFLEDYKKSVSERESEGIPPLPLNAKQVESVVEILTKDPTNAAFAKELLIHRVSPGV CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC DEGAKVKAEFLAKLSQKKLECAHISALEATTLLGTMLGGYNVEPLIMGLESQDKNIAKES CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHH AKALKTTLLVYGSFDKIAAMSQTNALAKEVLESWANAEWFLNKEPLNECIEACVFKIDGE HHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHEEEECCC TNTDDLSPASDAFTRSDIPLHAKAMLKNRIENYEQRIKAIKTKGVPVAYVGDVVGTGSSR CCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHCCCCCC KSATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVKDLKEGDL CHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCEEEECHHHCCCCCE IKIYPYKGEITLNDKVVSTFKLEPETLLDEVRASGRIPLIIGRGLTNKARKFLGLGESEA EEEEECCCEEEECCCEEEEEECCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCHHH FKKPSAPKSDAKGYTLAQKIVGHACGVKGILPGAYCEPKVTTVGSQDTTGAMTRDEVKEL CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHH ASLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPSFITQRGGVALHPGDGVIHTWLNRMGL HHCCCCCHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHCCCEEECCCCCHHHHHHHHCCC PDTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLVRFKGEMNPGITLRD CCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHEEECCCCCCCEEHHH LVNAIPYYAIKKGLLTVEKKGKINVFNGRILEIEGLPDIKMEQAFELSDASAERSAAACV HHHHHHHHHHHHCCEEEECCCEEEEECCEEEEECCCCCCCHHHHHCCCCCCHHHHHEEEE VRLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAMQAWVDKPVLLEPDSNAQYAA EEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEE VIEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDEVFIGSCMTNIGHFRAFG EEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH EIVKNAPPSQARLWVVPPSKMDEQELINEGYYAIFGAAGARTEVPGCSLCMGNQARVRDN HHHHCCCCCCCEEEEECCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCEECCCCCEECCC AVVFSTSTRNFDNRMGRGAKVYLGSAELGAACALLGRIPTKEEYMNLVSEKLESQKDKIY EEEEEECCCCHHHHCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH RYMNFNLMENFRL HHHCCCHHHHCCC >Mature Secondary Structure MMKDFLEDYKKSVSERESEGIPPLPLNAKQVESVVEILTKDPTNAAFAKELLIHRVSPGV CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC DEGAKVKAEFLAKLSQKKLECAHISALEATTLLGTMLGGYNVEPLIMGLESQDKNIAKES CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHH AKALKTTLLVYGSFDKIAAMSQTNALAKEVLESWANAEWFLNKEPLNECIEACVFKIDGE HHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHEEEECCC TNTDDLSPASDAFTRSDIPLHAKAMLKNRIENYEQRIKAIKTKGVPVAYVGDVVGTGSSR CCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHCCCCCC KSATNSIMWHFGKDIPFVPNKRSGGIVIGGVIAPIFFATCEDSGALPIVADVKDLKEGDL CHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCEEEECHHHCCCCCE IKIYPYKGEITLNDKVVSTFKLEPETLLDEVRASGRIPLIIGRGLTNKARKFLGLGESEA EEEEECCCEEEECCCEEEEEECCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCHHH FKKPSAPKSDAKGYTLAQKIVGHACGVKGILPGAYCEPKVTTVGSQDTTGAMTRDEVKEL CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHH ASLKFDAPFVLQSFCHTAAYPKPSDVSLHATLPSFITQRGGVALHPGDGVIHTWLNRMGL HHCCCCCHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHCCCEEECCCCCHHHHHHHHCCC PDTLGTGGDSHTRFPLGISFPAGSGLVAFAAVTGTMPLNMPESVLVRFKGEMNPGITLRD CCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHEEECCCCCCCEEHHH LVNAIPYYAIKKGLLTVEKKGKINVFNGRILEIEGLPDIKMEQAFELSDASAERSAAACV HHHHHHHHHHHHCCEEEECCCEEEEECCEEEEECCCCCCCHHHHHCCCCCCHHHHHEEEE VRLNKEPMIEYLKSNIKLIDEMIASGYEDKETLKKRRDAMQAWVDKPVLLEPDSNAQYAA EEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEE VIEIDVAEITEPILACPNDPDDVATLSEVLADTTGKRPHAIDEVFIGSCMTNIGHFRAFG EEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH EIVKNAPPSQARLWVVPPSKMDEQELINEGYYAIFGAAGARTEVPGCSLCMGNQARVRDN HHHHCCCCCCCEEEEECCCCCCHHHHHHCCCEEEEECCCCCCCCCCCCEECCCCCEECCC AVVFSTSTRNFDNRMGRGAKVYLGSAELGAACALLGRIPTKEEYMNLVSEKLESQKDKIY EEEEEECCCCHHHHCCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH RYMNFNLMENFRL HHHCCCHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9923682 [H]