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The map label for this gene is modB [H]

Identifier: 108562876

GI number: 108562876

Start: 463274

End: 463948

Strand: Direct

Name: modB [H]

Synonym: HPAG1_0451

Alternate gene names: 108562876

Gene position: 463274-463948 (Clockwise)

Preceding gene: 108562875

Following gene: 108562877

Centisome position: 29.02

GC content: 36.59

Gene sequence:

>675_bases
ATGGATCATGAGTTTTTGATTACCATGCGTTTGAGCTTTTCTTTAGCTTTGATTACCACCCTTATTTTACTCCCTATAGG
GATTTTTTTAGGCTATTTTTTAAGCCTTAAACGCAATCTTTTAACGAGCTTAACAGAAACGCTTGTGTATATGCCTTTAG
TTTTACCCCCAAGCGTGCTAGGGTTTTATCTTCTTTTAATCTTTTCGCCTTCTTCTTTTTTGGGAGCGTTTTTACAAGAT
GTATTAAATGTGAAACTTGTTTTTAGTTTTCAAGGGCTTATTTTAGGGAGTGTGATTTTTTCTTTACCCTTTATGGTAAT
CCCTATTAAAAGCGCGTTAATTTCCTTGCCTGCTTCTTTAAAAGAAGCCAGTTATAGTTTGGGTAAGGGGGAATATTACA
CCCTTTTTTTTGTCCTACTCCCTAACATCAAACCCAGTTTATTGATGGCTATCATCACAACTTTTACGCACACTATAGGT
GAATTTGGCGTGGTGATGATGCTTGGGGGTGATATATTAGGGGAAACAAGAGTGGCCAGCATTGCGATTTTTAACGAAAC
TGAAGCGCTCAATTACCCTAAAGCCCACCAATACGCCTTAACGCTCACGCTTATCAGTTTTAGTCTCTTATTTGTTACCC
TATTTTTGAATAAAAAACAAAGTTCGTTTTTATGA

Upstream 100 bases:

>100_bases
AGCCAAAGTCTTTAAAGATTTTTTATTCAGCCCTAAAGCCAGAGCTATTTTTAAAGAATATGGCTATATTGTGGATTAAA
ACGCATAAAAAAGGCGAACA

Downstream 100 bases:

>100_bases
TAAAAGCGCGGTTTAAAAAACGCCTTTTAGGATCTAGGGGCGCGTTTGATTTGAATATAGACTTAGAAATTAAAAAAGCA
GAAGTTGTCGCTTTATTAGG

Product: molybdenum ABC transporter ModB

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MDHEFLITMRLSFSLALITTLILLPIGIFLGYFLSLKRNLLTSLTETLVYMPLVLPPSVLGFYLLLIFSPSSFLGAFLQD
VLNVKLVFSFQGLILGSVIFSLPFMVIPIKSALISLPASLKEASYSLGKGEYYTLFFVLLPNIKPSLLMAIITTFTHTIG
EFGVVMMLGGDILGETRVASIAIFNETEALNYPKAHQYALTLTLISFSLLFVTLFLNKKQSSFL

Sequences:

>Translated_224_residues
MDHEFLITMRLSFSLALITTLILLPIGIFLGYFLSLKRNLLTSLTETLVYMPLVLPPSVLGFYLLLIFSPSSFLGAFLQD
VLNVKLVFSFQGLILGSVIFSLPFMVIPIKSALISLPASLKEASYSLGKGEYYTLFFVLLPNIKPSLLMAIITTFTHTIG
EFGVVMMLGGDILGETRVASIAIFNETEALNYPKAHQYALTLTLISFSLLFVTLFLNKKQSSFL
>Mature_224_residues
MDHEFLITMRLSFSLALITTLILLPIGIFLGYFLSLKRNLLTSLTETLVYMPLVLPPSVLGFYLLLIFSPSSFLGAFLQD
VLNVKLVFSFQGLILGSVIFSLPFMVIPIKSALISLPASLKEASYSLGKGEYYTLFFVLLPNIKPSLLMAIITTFTHTIG
EFGVVMMLGGDILGETRVASIAIFNETEALNYPKAHQYALTLTLISFSLLFVTLFLNKKQSSFL

Specific function: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4149

COG function: function code P; ABC-type molybdate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=197, Percent_Identity=28.9340101522843, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1786980, Length=217, Percent_Identity=29.4930875576037, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082099, Length=179, Percent_Identity=31.8435754189944, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011867 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24824; Mature: 24824

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHEFLITMRLSFSLALITTLILLPIGIFLGYFLSLKRNLLTSLTETLVYMPLVLPPSVL
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GFYLLLIFSPSSFLGAFLQDVLNVKLVFSFQGLILGSVIFSLPFMVIPIKSALISLPASL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
KEASYSLGKGEYYTLFFVLLPNIKPSLLMAIITTFTHTIGEFGVVMMLGGDILGETRVAS
HHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHEE
IAIFNETEALNYPKAHQYALTLTLISFSLLFVTLFLNKKQSSFL
EEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MDHEFLITMRLSFSLALITTLILLPIGIFLGYFLSLKRNLLTSLTETLVYMPLVLPPSVL
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GFYLLLIFSPSSFLGAFLQDVLNVKLVFSFQGLILGSVIFSLPFMVIPIKSALISLPASL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
KEASYSLGKGEYYTLFFVLLPNIKPSLLMAIITTFTHTIGEFGVVMMLGGDILGETRVAS
HHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHEE
IAIFNETEALNYPKAHQYALTLTLISFSLLFVTLFLNKKQSSFL
EEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8491722 [H]