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The map label for this gene is nixA [H]

Identifier: 108562795

GI number: 108562795

Start: 382880

End: 383875

Strand: Direct

Name: nixA [H]

Synonym: HPAG1_0370

Alternate gene names: 108562795

Gene position: 382880-383875 (Clockwise)

Preceding gene: 108562794

Following gene: 108562797

Centisome position: 23.98

GC content: 41.57

Gene sequence:

>996_bases
GTGAAATTGTGGTTTCCTTATTTTTTAGCGATTGTGTTCTTGCATGCATTAGGTTTAGCGTTGCTCTTTATGGCCAATAA
CGCTTCGTTTTATGCGGCGGCTTCTATGGCTTACATGCTAGGGGCAAAGCATGCCTTTGATGCAGATCACATCGCTTGCA
TAGACAACACCATTAGAAAGCTCACCCAACAAGGCAAAAACGCCTATGGTGTGGGGTTTTACTTTTCTATGGGGCATTCA
AGCGTGGTGATTTTAATGACTATTATCAGCGCGTTTGCGATCGCTTGGGCCAAAGAGCATACGCCGATGCTAGAAGAAAT
AGGGGGGGTAGTGGGGACTTTAGTTTCTGGGCTTTTTTTGCTCATTATAGGGCTATTGAATGCGATTATTCTCTTGGATT
TATTAAAAATATTCAAAAAATCGCACTCTAATGAAAGCTTAAGCCAGCAACAAAATGAAGAGATTGAACGGCTTTTAACG
AGTAGGGGCTTGCTCAACCGCTTTTTTAAGCCTTTGTTTAATTTCGTTTCCAAGTCGTGGCATATTTATCCTATCGGGTT
TCTTTTTGGGTTGGGTTTTGATACCGCTAGTGAAATCGCGCTTTTGGCCCTCTCTAGCAGCGCGATTAAAGTGAGTGTGG
TGGGCATGCTTTCTTTACCCATTCTTTTTGCCGCTGGCATGAGCTTGTTTGACACATTAGATGGGGCGTTCATGCTCAAG
GCGTATGATTGGGCGTTCAAAACCCCTTTAAGAAAAATCTACTACAACATCTCCATCACCGCCTTAAGCGTGTTTATCGC
GCTTTTTATCGGGTTGATTGAGCTTTTTCAAGTGTTTAGCGAGAAACTCCATTTAAAATTTGAAAACCGCCTTCTAAACG
CCTTACAAAGCTTGGAATTTACAGACTTGGGCTATTACTTGGTGGGCTTATTTGTAATAGCGTTTTTAGGCTCATTCTTT
TTATGGAAAATCAAATTTTCTAAATTAGAGAGCTGA

Upstream 100 bases:

>100_bases
ATTTGCAGAAAATAATCAAAAACCAAATCCTAAAATTTTCTAATTTAACAAAATATATTACAATTATCCAAAAAATATTA
TTTTTACAAAAAGGTGCACT

Downstream 100 bases:

>100_bases
ATTTTAAGCCCTCAAATTATCGCTTAACAAATCTTTAAGGCTTTGATTTGAAAAACTTTGTTTTGGCATGAAGGCTTTAG
GGTTTGAAAGGCTTTCGCTC

Product: high affinity nickel transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKLWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNAYGVGFYFSMGHS
SVVILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFLLIIGLLNAIILLDLLKIFKKSHSNESLSQQQNEEIERLLT
SRGLLNRFFKPLFNFVSKSWHIYPIGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLK
AYDWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVFSEKLHLKFENRLLNALQSLEFTDLGYYLVGLFVIAFLGSFF
LWKIKFSKLES

Sequences:

>Translated_331_residues
MKLWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNAYGVGFYFSMGHS
SVVILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFLLIIGLLNAIILLDLLKIFKKSHSNESLSQQQNEEIERLLT
SRGLLNRFFKPLFNFVSKSWHIYPIGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLK
AYDWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVFSEKLHLKFENRLLNALQSLEFTDLGYYLVGLFVIAFLGSFF
LWKIKFSKLES
>Mature_331_residues
MKLWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNAYGVGFYFSMGHS
SVVILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFLLIIGLLNAIILLDLLKIFKKSHSNESLSQQQNEEIERLLT
SRGLLNRFFKPLFNFVSKSWHIYPIGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLK
AYDWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVFSEKLHLKFENRLLNALQSLEFTDLGYYLVGLFVIAFLGSFF
LWKIKFSKLES

Specific function: High-affinity nickel intake protein. Imports nickel ions in an energy-dependent fashion. Necessary for the expression of catalytically active urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 37008; Mature: 37008

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LTQQGKNAYGVGFYFSMGHSSVVILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFL
HHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LIIGLLNAIILLDLLKIFKKSHSNESLSQQQNEEIERLLTSRGLLNRFFKPLFNFVSKSW
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HIYPIGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLK
EEEEHHHHHHCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AYDWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVFSEKLHLKFENRLLNALQSLEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TDLGYYLVGLFVIAFLGSFFLWKIKFSKLES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LTQQGKNAYGVGFYFSMGHSSVVILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFL
HHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LIIGLLNAIILLDLLKIFKKSHSNESLSQQQNEEIERLLTSRGLLNRFFKPLFNFVSKSW
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HIYPIGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLK
EEEEHHHHHHCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AYDWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVFSEKLHLKFENRLLNALQSLEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TDLGYYLVGLFVIAFLGSFFLWKIKFSKLES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]