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The map label for this gene is gpmA

Identifier: 103488306

GI number: 103488306

Start: 2985157

End: 2985843

Strand: Reverse

Name: gpmA

Synonym: Sala_2829

Alternate gene names: 103488306

Gene position: 2985843-2985157 (Counterclockwise)

Preceding gene: 103488308

Following gene: 103488303

Centisome position: 89.26

GC content: 64.63

Gene sequence:

>687_bases
ATGCCCCAGCTCATCCTCATCCGTCATGGCCAGTCGCAGTGGAATCTCGAAAACCGCTTCACCGGCTGGTGGGATGTCGA
TGTCACCGAAAAGGGTGCGGCCGAAGCCTGGGCGGCGGGCGAACTGATGAAGGCGAAGGGCGTCGCGCCCGACACCTGTT
TCACCTCCGTCCAGACGCGCGCGATCAAGACATTGAACCTCGCGCTCGAGGCAATGGGCCGCCTGTGGCTGCCGGTGACG
AAGGACTGGCGGCTCAACGAACGCCACTATGGCGGGCTCACCGGGCTCGACAAGGCCGAGACCGCGGCCAAGCATGGTGA
CGAGCAGGTCAGGATATGGCGCCGCAGCTTCGACATCCCGCCGCCGCCGCTCGAAGCCGGGTCGCAATGGGATCTGTCCG
CCGACCCGCGTTACGCCGGCATCGCGATTCCGTCGACCGAAAGCCTGAAGGACACGATCGCGCGCGTGCTTCCCTATTAT
GAAGCCGCGATCGCGCCGCAGCTTGCCGCGGGCAGAACGGTGCTGATCTCGGCGCACGGCAACAGCCTGCGCGCGCTCGT
CAAGCATCTGTCGGGCATTTCGGACGCCGACATCACCGGCCTCGAAATCCCGACCGGCCAGCCGATCGTTTATGAAATCA
ACGACGATCTGAGCGCGCGCGAGCGCTATTATCTCAGCGAGCGGTAA

Upstream 100 bases:

>100_bases
GCCAATCTGGTAGCCGCTGAAACCATTTCAAGAGGGGCGTTGGCCTTTACGGAAAAGCCGCGCTAAAGGGCGGCGAAACC
GTTTGTCCAAAGGATCCGAC

Downstream 100 bases:

>100_bases
GTCCCGTCAATCGCGCAGCAGCTCGTTGATTCCCGTCTTGGCGCGCGTCTGCGCGTCGACGCGCTTGACGATCACCGCAC
AGTAAAGCGACGGGCCGGGC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MPQLILIRHGQSQWNLENRFTGWWDVDVTEKGAAEAWAAGELMKAKGVAPDTCFTSVQTRAIKTLNLALEAMGRLWLPVT
KDWRLNERHYGGLTGLDKAETAAKHGDEQVRIWRRSFDIPPPPLEAGSQWDLSADPRYAGIAIPSTESLKDTIARVLPYY
EAAIAPQLAAGRTVLISAHGNSLRALVKHLSGISDADITGLEIPTGQPIVYEINDDLSARERYYLSER

Sequences:

>Translated_228_residues
MPQLILIRHGQSQWNLENRFTGWWDVDVTEKGAAEAWAAGELMKAKGVAPDTCFTSVQTRAIKTLNLALEAMGRLWLPVT
KDWRLNERHYGGLTGLDKAETAAKHGDEQVRIWRRSFDIPPPPLEAGSQWDLSADPRYAGIAIPSTESLKDTIARVLPYY
EAAIAPQLAAGRTVLISAHGNSLRALVKHLSGISDADITGLEIPTGQPIVYEINDDLSARERYYLSER
>Mature_227_residues
PQLILIRHGQSQWNLENRFTGWWDVDVTEKGAAEAWAAGELMKAKGVAPDTCFTSVQTRAIKTLNLALEAMGRLWLPVTK
DWRLNERHYGGLTGLDKAETAAKHGDEQVRIWRRSFDIPPPPLEAGSQWDLSADPRYAGIAIPSTESLKDTIARVLPYYE
AAIAPQLAAGRTVLISAHGNSLRALVKHLSGISDADITGLEIPTGQPIVYEINDDLSARERYYLSER

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=221, Percent_Identity=56.1085972850679, Blast_Score=263, Evalue=7e-71,
Organism=Homo sapiens, GI4505753, Length=221, Percent_Identity=57.0135746606335, Blast_Score=251, Evalue=4e-67,
Organism=Homo sapiens, GI71274132, Length=221, Percent_Identity=53.8461538461538, Blast_Score=236, Evalue=1e-62,
Organism=Homo sapiens, GI4502445, Length=224, Percent_Identity=47.7678571428571, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI40353764, Length=224, Percent_Identity=47.7678571428571, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=59.0062111801242, Blast_Score=185, Evalue=4e-47,
Organism=Escherichia coli, GI1786970, Length=226, Percent_Identity=53.9823008849557, Blast_Score=253, Evalue=8e-69,
Organism=Saccharomyces cerevisiae, GI6322697, Length=229, Percent_Identity=55.4585152838428, Blast_Score=264, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6324516, Length=275, Percent_Identity=29.4545454545455, Blast_Score=125, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6320183, Length=280, Percent_Identity=30.3571428571429, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24646216, Length=221, Percent_Identity=52.0361990950226, Blast_Score=237, Evalue=6e-63,
Organism=Drosophila melanogaster, GI85725270, Length=222, Percent_Identity=51.8018018018018, Blast_Score=221, Evalue=3e-58,
Organism=Drosophila melanogaster, GI85725272, Length=222, Percent_Identity=51.8018018018018, Blast_Score=221, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24650981, Length=222, Percent_Identity=51.8018018018018, Blast_Score=221, Evalue=3e-58,
Organism=Drosophila melanogaster, GI28571815, Length=219, Percent_Identity=36.0730593607306, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28571817, Length=219, Percent_Identity=36.0730593607306, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24648979, Length=219, Percent_Identity=36.0730593607306, Blast_Score=152, Evalue=2e-37,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_SPHAL (Q1GP88)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_617867.1
- ProteinModelPortal:   Q1GP88
- SMR:   Q1GP88
- GeneID:   4080410
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_2829
- NMPDR:   fig|317655.9.peg.2694
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- ProtClustDB:   PRK14115
- BioCyc:   SALA317655:SALA_2829-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 25288; Mature: 25157

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 9-9 ACT_SITE 179-179

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQLILIRHGQSQWNLENRFTGWWDVDVTEKGAAEAWAAGELMKAKGVAPDTCFTSVQTR
CCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
AIKTLNLALEAMGRLWLPVTKDWRLNERHYGGLTGLDKAETAAKHGDEQVRIWRRSFDIP
HHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHEEHHHHHCCCC
PPPLEAGSQWDLSADPRYAGIAIPSTESLKDTIARVLPYYEAAIAPQLAAGRTVLISAHG
CCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHCCCCEEEEEECC
NSLRALVKHLSGISDADITGLEIPTGQPIVYEINDDLSARERYYLSER
CHHHHHHHHHCCCCCCCCCEEECCCCCEEEEEECCCCCHHHHEECCCC
>Mature Secondary Structure 
PQLILIRHGQSQWNLENRFTGWWDVDVTEKGAAEAWAAGELMKAKGVAPDTCFTSVQTR
CCEEEEECCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
AIKTLNLALEAMGRLWLPVTKDWRLNERHYGGLTGLDKAETAAKHGDEQVRIWRRSFDIP
HHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHEEHHHHHCCCC
PPPLEAGSQWDLSADPRYAGIAIPSTESLKDTIARVLPYYEAAIAPQLAAGRTVLISAHG
CCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHCCCCEEEEEECC
NSLRALVKHLSGISDADITGLEIPTGQPIVYEINDDLSARERYYLSER
CHHHHHHHHHCCCCCCCCCEEECCCCCEEEEEECCCCCHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA