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The map label for this gene is nupX [H]

Identifier: 103488174

GI number: 103488174

Start: 2837488

End: 2838753

Strand: Reverse

Name: nupX [H]

Synonym: Sala_2697

Alternate gene names: 103488174

Gene position: 2838753-2837488 (Counterclockwise)

Preceding gene: 103488175

Following gene: 103488173

Centisome position: 84.86

GC content: 66.98

Gene sequence:

>1266_bases
ATGGCGTGGCTCGCAAACCTGCAGGGACTGGTCGGCCTGACGGCCATCCTGCTGCTGGCCTGGCTTCTCTCCGAGGATCG
CCGCGCCCGGCCGGGCTGGCGCTGGATCGGCGGCGCGCTGCTGCTCCAGCTTGCCATCGCTTTCACAGTGACGCGCATCC
CCTTTGTCTGGACCCTTGTCGGTTTTGCCAACGGCGCGGTCACGGCGATCGAGAAAGCGACGCTTGTCGGGTCGAGCTAC
ATGTTCGGCTATACCGGCGGCGCCCCGATCCCGTTCCTGCTCAAGCCCGGCGCCGAGCCGCCGGTCGTGATCGCCTTTCA
GATACTGCCGCTGATCATCGTCTTTTCAGCGATCTCGGCGTTGCTCTGGCACTGGGGTGTGCTGCGCGCGCTGGTTCGCG
GGCTGTCGTGGGCGCTACGCAGGACGCTTGGAGTCAGCGGGGTCGTCGGCCTCGGCGGCGGCGCGACGATCTTCCTCGGC
GTTGTCGAATCGCCGCTCGTGCTGCGCGCCTGGTTCGACCGGATGAGCCGCGCCGAACTGTTCATGATCATGGTGATGAT
CATGGCGACGATCTCGGGCGCGATCCTGATTCTCTATGCCACCACGCTCGCGAAGACGGTGCCGAACGCGGTCGGCCACA
TGATCGTTGCGTCACTCATTTCGCTTCCGGCAGGAGTGCTGGTCGCGCGGATCATCGTGCCGGGCGACGGTTCGCCGGGC
GCCGATGCCGCCGAACCCGACCTTGCCTATGAAAGCAGCATGGATGCGGTGGTCCGCGGCACCATGGAGGGCGTCCAGCT
CGTCCTCGCGGTGATCGGGATCATCATTGTCGTCTTCGCGCTCGTCAATCTCGCCGACCAGCTGCTTGCGCTGCTGCCGC
CGGCCAATGGGGCGCCGCTGACGCTCCAGCGGCTGTTCGGCTGGCTGTTCGCGCCGCTGATGTGGGCGATCGGCATTCCC
TGGGAGCAGGCGCCCGCTGCGGGCGGGCTGATGGGGACGAAGGCGATCCTCAACGAATATGTGGCGTACCTCGGCCTTGC
CGCGATGCCCGCCGGGACGCTCGATCCGCGCAGCCTGCTGATCACGACCTATGCTTTGAGCGGGGTCGCCAATCTTGCGA
GCGTCGGCCTTCTCGTCTCGACGATCGCGACGCTGGCGCCGAAGCGCCGCCGCGATGTCGCGGAGCTCGGGATGAAGAGC
TGGATCGCGGGCAACATGGCGTCGGCGATGACCGGGGCGGTCATCGGTCTCGTGACCTGGGCCTAG

Upstream 100 bases:

>100_bases
GCAGTTCGGTGGCGGGGCGCCCTTCGTGCAGCGCAATGCCGGGCCGCCGCGCCAGTTCCAGTTCGGCGCGGCATGGAAGT
TTTAGGGGAGACATAGGCGG

Downstream 100 bases:

>100_bases
AGCGATGTTCGATGCCCGACTTCGCCCTCTGATCGACCCGCCGCTCAATGCAGCGGGGCGCCGGCTCGCCGCTTGGGGCA
TCGGCGCCGATGCCGTGACG

Product: Na+ dependent nucleoside transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MAWLANLQGLVGLTAILLLAWLLSEDRRARPGWRWIGGALLLQLAIAFTVTRIPFVWTLVGFANGAVTAIEKATLVGSSY
MFGYTGGAPIPFLLKPGAEPPVVIAFQILPLIIVFSAISALLWHWGVLRALVRGLSWALRRTLGVSGVVGLGGGATIFLG
VVESPLVLRAWFDRMSRAELFMIMVMIMATISGAILILYATTLAKTVPNAVGHMIVASLISLPAGVLVARIIVPGDGSPG
ADAAEPDLAYESSMDAVVRGTMEGVQLVLAVIGIIIVVFALVNLADQLLALLPPANGAPLTLQRLFGWLFAPLMWAIGIP
WEQAPAAGGLMGTKAILNEYVAYLGLAAMPAGTLDPRSLLITTYALSGVANLASVGLLVSTIATLAPKRRRDVAELGMKS
WIAGNMASAMTGAVIGLVTWA

Sequences:

>Translated_421_residues
MAWLANLQGLVGLTAILLLAWLLSEDRRARPGWRWIGGALLLQLAIAFTVTRIPFVWTLVGFANGAVTAIEKATLVGSSY
MFGYTGGAPIPFLLKPGAEPPVVIAFQILPLIIVFSAISALLWHWGVLRALVRGLSWALRRTLGVSGVVGLGGGATIFLG
VVESPLVLRAWFDRMSRAELFMIMVMIMATISGAILILYATTLAKTVPNAVGHMIVASLISLPAGVLVARIIVPGDGSPG
ADAAEPDLAYESSMDAVVRGTMEGVQLVLAVIGIIIVVFALVNLADQLLALLPPANGAPLTLQRLFGWLFAPLMWAIGIP
WEQAPAAGGLMGTKAILNEYVAYLGLAAMPAGTLDPRSLLITTYALSGVANLASVGLLVSTIATLAPKRRRDVAELGMKS
WIAGNMASAMTGAVIGLVTWA
>Mature_420_residues
AWLANLQGLVGLTAILLLAWLLSEDRRARPGWRWIGGALLLQLAIAFTVTRIPFVWTLVGFANGAVTAIEKATLVGSSYM
FGYTGGAPIPFLLKPGAEPPVVIAFQILPLIIVFSAISALLWHWGVLRALVRGLSWALRRTLGVSGVVGLGGGATIFLGV
VESPLVLRAWFDRMSRAELFMIMVMIMATISGAILILYATTLAKTVPNAVGHMIVASLISLPAGVLVARIIVPGDGSPGA
DAAEPDLAYESSMDAVVRGTMEGVQLVLAVIGIIIVVFALVNLADQLLALLPPANGAPLTLQRLFGWLFAPLMWAIGIPW
EQAPAAGGLMGTKAILNEYVAYLGLAAMPAGTLDPRSLLITTYALSGVANLASVGLLVSTIATLAPKRRRDVAELGMKSW
IAGNMASAMTGAVIGLVTWA

Specific function: Nucleoside transporter [H]

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI11545853, Length=336, Percent_Identity=27.3809523809524, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI227116277, Length=430, Percent_Identity=25.5813953488372, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI42542381, Length=437, Percent_Identity=23.7986270022883, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1788485, Length=424, Percent_Identity=30.6603773584906, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1788488, Length=420, Percent_Identity=31.1904761904762, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1788737, Length=423, Percent_Identity=22.4586288416076, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71991794, Length=420, Percent_Identity=26.9047619047619, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17560276, Length=401, Percent_Identity=27.431421446384, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25146537, Length=221, Percent_Identity=25.7918552036199, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45552517, Length=430, Percent_Identity=28.1395348837209, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI19921868, Length=430, Percent_Identity=28.1395348837209, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI45552519, Length=430, Percent_Identity=28.1395348837209, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI281360430, Length=415, Percent_Identity=25.5421686746988, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 44204; Mature: 44073

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWLANLQGLVGLTAILLLAWLLSEDRRARPGWRWIGGALLLQLAIAFTVTRIPFVWTLV
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFANGAVTAIEKATLVGSSYMFGYTGGAPIPFLLKPGAEPPVVIAFQILPLIIVFSAISA
HHCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHH
LLWHWGVLRALVRGLSWALRRTLGVSGVVGLGGGATIFLGVVESPLVLRAWFDRMSRAEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
FMIMVMIMATISGAILILYATTLAKTVPNAVGHMIVASLISLPAGVLVARIIVPGDGSPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCC
ADAAEPDLAYESSMDAVVRGTMEGVQLVLAVIGIIIVVFALVNLADQLLALLPPANGAPL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
TLQRLFGWLFAPLMWAIGIPWEQAPAAGGLMGTKAILNEYVAYLGLAAMPAGTLDPRSLL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ITTYALSGVANLASVGLLVSTIATLAPKRRRDVAELGMKSWIAGNMASAMTGAVIGLVTW
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
A
C
>Mature Secondary Structure 
AWLANLQGLVGLTAILLLAWLLSEDRRARPGWRWIGGALLLQLAIAFTVTRIPFVWTLV
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFANGAVTAIEKATLVGSSYMFGYTGGAPIPFLLKPGAEPPVVIAFQILPLIIVFSAISA
HHCCCHHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHH
LLWHWGVLRALVRGLSWALRRTLGVSGVVGLGGGATIFLGVVESPLVLRAWFDRMSRAEL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
FMIMVMIMATISGAILILYATTLAKTVPNAVGHMIVASLISLPAGVLVARIIVPGDGSPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEECCCCCCC
ADAAEPDLAYESSMDAVVRGTMEGVQLVLAVIGIIIVVFALVNLADQLLALLPPANGAPL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
TLQRLFGWLFAPLMWAIGIPWEQAPAAGGLMGTKAILNEYVAYLGLAAMPAGTLDPRSLL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ITTYALSGVANLASVGLLVSTIATLAPKRRRDVAELGMKSWIAGNMASAMTGAVIGLVTW
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]