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The map label for this gene is hmrR2 [H]

Identifier: 103488021

GI number: 103488021

Start: 2681659

End: 2682045

Strand: Reverse

Name: hmrR2 [H]

Synonym: Sala_2543

Alternate gene names: 103488021

Gene position: 2682045-2681659 (Counterclockwise)

Preceding gene: 103488022

Following gene: 103488020

Centisome position: 80.18

GC content: 59.69

Gene sequence:

>387_bases
ATGAATATCGGAGCAGCATCGGAAACGAGCGGGGTCTCGCAGCGGATGATCCGCCACTATGAGAAGATCGGCCTAATCCC
TTCGCCACCGCGACGCGAGAGCGGCTATCGGGATTATTCCGATGCAGATGTGCATCGCCTGCGATTCATCGCCAATGCCC
GCGACCTGGGTTTCCCGATCGAGGAGATCCGAAGCCTCCTCGATCTCTGGGCCGACCGCAACCGCGCGAGTTCCGAAGTC
AAGATACTTGCGGAAGCACGAGCCACCGAACTTGGGAAGAAGGCAGCGGCATTGCAGGCCATGCAGAGCACATTGCTGTC
CCTGGCCAAGCATTGCCACGGCGATGATCGGCCCGACTGCCCAATCATCGACCGGCTTCAGGAATGA

Upstream 100 bases:

>100_bases
TCTTCGGCATCCTGCTGTCGCCGATCCTTGCGGCGGCCGCCATGGCGTTGTCATCGGTGAGCGTGGTCATGAATGCGCTG
AGACTCAATCGGGTAACGCT

Downstream 100 bases:

>100_bases
TCTCCGAGCGGCCGCCCATGTGATCCATGGCCATTCGGAGGACGATGCACAACGCGCGTGCGCGAAGCTTCGCAAGACAT
GCAGACGAGCGGACAGTCAC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MNIGAASETSGVSQRMIRHYEKIGLIPSPPRRESGYRDYSDADVHRLRFIANARDLGFPIEEIRSLLDLWADRNRASSEV
KILAEARATELGKKAAALQAMQSTLLSLAKHCHGDDRPDCPIIDRLQE

Sequences:

>Translated_128_residues
MNIGAASETSGVSQRMIRHYEKIGLIPSPPRRESGYRDYSDADVHRLRFIANARDLGFPIEEIRSLLDLWADRNRASSEV
KILAEARATELGKKAAALQAMQSTLLSLAKHCHGDDRPDCPIIDRLQE
>Mature_128_residues
MNIGAASETSGVSQRMIRHYEKIGLIPSPPRRESGYRDYSDADVHRLRFIANARDLGFPIEEIRSLLDLWADRNRASSEV
KILAEARATELGKKAAALQAMQSTLLSLAKHCHGDDRPDCPIIDRLQE

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=126, Percent_Identity=38.8888888888889, Blast_Score=100, Evalue=4e-23,
Organism=Escherichia coli, GI1789687, Length=129, Percent_Identity=34.8837209302326, Blast_Score=78, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 14341; Mature: 14341

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGAASETSGVSQRMIRHYEKIGLIPSPPRRESGYRDYSDADVHRLRFIANARDLGFPI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
EEIRSLLDLWADRNRASSEVKILAEARATELGKKAAALQAMQSTLLSLAKHCHGDDRPDC
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PIIDRLQE
CHHHHHCC
>Mature Secondary Structure
MNIGAASETSGVSQRMIRHYEKIGLIPSPPRRESGYRDYSDADVHRLRFIANARDLGFPI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
EEIRSLLDLWADRNRASSEVKILAEARATELGKKAAALQAMQSTLLSLAKHCHGDDRPDC
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PIIDRLQE
CHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]