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The map label for this gene is nadA [H]

Identifier: 103485960

GI number: 103485960

Start: 480514

End: 481503

Strand: Direct

Name: nadA [H]

Synonym: Sala_0467

Alternate gene names: 103485960

Gene position: 480514-481503 (Clockwise)

Preceding gene: 103485959

Following gene: 103485962

Centisome position: 14.36

GC content: 62.12

Gene sequence:

>990_bases
ATGACTGCCCCCATCCGCGACTCGCTCTCGGGCCTCGACCTGCGCGCCGAAATCGACCGCCTCCGCAAGGAGCGCAACGC
CGTCATCCTCGCGCATTATTACCAGAAGCCCGAGATTCAGGATCTCGCCGATTTCGTGGGCGATTCGCTCGAACTGTCGC
GCAAGGCGGCCGAAACCGACGCCGAAGTGATCGCCTTTTGCGGTGTCAAGTTCATGGCCGAAACCGCGAAGATACTGAGC
CCCGAAAAGATCGTCATCCTGCCCGACATGGACGCGGGATGCAGCCTCGAGGACAGCTGCCCGCCCGAACAGTTCAAGCG
TTTCCGCGAAAAGCATCCCGATCATATTGCGCTCACCTACATCAACTGCTCGGCGGCAGTGAAAGCCTTGAGCGACATCA
TCGTCACCTCGTCGAGCGCCGAGACGATCATCAGCCAGATCCCACCCGAACAGAAGATCATTTTTGGCCCCGACCGCCAC
CTTGGCGGCTATATGAACCGCAAGTTCGGGCGTGACATGCTGCTGTGGCCCGGCGTGTGCATCGTCCACGAGGCGTTCAG
CGAGACCGAGCTTCTGAAGCTGAAGGCGCAGTATCCCGGCGCGCCGGTCGCGGCGCACCCCGAATGTCCGCCGCACATCG
TCGAGCATGCCGATTATGTCGGGTCGACCAGCGGCATCCTGCAATTCGCGAAGAGTTTCAAGGGCGACACGCTGATCGTC
GCGACCGAGCCGCACATCATTCACCAGATGGAGCTGGCGCTGCCCGAAAAGACTTTCATCGGCGCGCCGGGCGCCGACGG
CAACTGCAACTGCAACATCTGCCCCTATATGGCGCTCAATACGATGGAGAAGCTCTACATCGCGCTGCGCGACCTTCAGC
CGCGGATCGAGATGGACGAGGAGCTTCGCCTCGCGGCGCGCAAAAGCCTCGACCGGATGTTGGAGATGGCGTCGGGGACG
GTCGGCAAGGGCGATCTGGGGCGGGCGTGA

Upstream 100 bases:

>100_bases
TCGCACTTGCGGCGCGCCGCGTCGGCTGACGCGGCGAATTGCCCTGCCGTGGGGCAGGGTGTAGGGGGGCGCCACGGCCA
GGCCATATAAGGATAACGCC

Downstream 100 bases:

>100_bases
GTCGCGACTCGGTCGGGTGATTCGACCGATCCAAAGATCGAGTCGAAGCGCTTTGGCGGGAAACCCGAGTCCAAAAATGC
TGCACCCTTGTTACAAAAAT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTAPIRDSLSGLDLRAEIDRLRKERNAVILAHYYQKPEIQDLADFVGDSLELSRKAAETDAEVIAFCGVKFMAETAKILS
PEKIVILPDMDAGCSLEDSCPPEQFKRFREKHPDHIALTYINCSAAVKALSDIIVTSSSAETIISQIPPEQKIIFGPDRH
LGGYMNRKFGRDMLLWPGVCIVHEAFSETELLKLKAQYPGAPVAAHPECPPHIVEHADYVGSTSGILQFAKSFKGDTLIV
ATEPHIIHQMELALPEKTFIGAPGADGNCNCNICPYMALNTMEKLYIALRDLQPRIEMDEELRLAARKSLDRMLEMASGT
VGKGDLGRA

Sequences:

>Translated_329_residues
MTAPIRDSLSGLDLRAEIDRLRKERNAVILAHYYQKPEIQDLADFVGDSLELSRKAAETDAEVIAFCGVKFMAETAKILS
PEKIVILPDMDAGCSLEDSCPPEQFKRFREKHPDHIALTYINCSAAVKALSDIIVTSSSAETIISQIPPEQKIIFGPDRH
LGGYMNRKFGRDMLLWPGVCIVHEAFSETELLKLKAQYPGAPVAAHPECPPHIVEHADYVGSTSGILQFAKSFKGDTLIV
ATEPHIIHQMELALPEKTFIGAPGADGNCNCNICPYMALNTMEKLYIALRDLQPRIEMDEELRLAARKSLDRMLEMASGT
VGKGDLGRA
>Mature_328_residues
TAPIRDSLSGLDLRAEIDRLRKERNAVILAHYYQKPEIQDLADFVGDSLELSRKAAETDAEVIAFCGVKFMAETAKILSP
EKIVILPDMDAGCSLEDSCPPEQFKRFREKHPDHIALTYINCSAAVKALSDIIVTSSSAETIISQIPPEQKIIFGPDRHL
GGYMNRKFGRDMLLWPGVCIVHEAFSETELLKLKAQYPGAPVAAHPECPPHIVEHADYVGSTSGILQFAKSFKGDTLIVA
TEPHIIHQMELALPEKTFIGAPGADGNCNCNICPYMALNTMEKLYIALRDLQPRIEMDEELRLAARKSLDRMLEMASGTV
GKGDLGRA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=318, Percent_Identity=44.6540880503145, Blast_Score=260, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 36318; Mature: 36187

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPIRDSLSGLDLRAEIDRLRKERNAVILAHYYQKPEIQDLADFVGDSLELSRKAAETD
CCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHCH
AEVIAFCGVKFMAETAKILSPEKIVILPDMDAGCSLEDSCPPEQFKRFREKHPDHIALTY
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEE
INCSAAVKALSDIIVTSSSAETIISQIPPEQKIIFGPDRHLGGYMNRKFGRDMLLWPGVC
EEHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCHHHCCHHHHHHCCCEEECCCHH
IVHEAFSETELLKLKAQYPGAPVAAHPECPPHIVEHADYVGSTSGILQFAKSFKGDTLIV
HHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCEEEE
ATEPHIIHQMELALPEKTFIGAPGADGNCNCNICPYMALNTMEKLYIALRDLQPRIEMDE
ECCCHHHHHHHHHCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCH
ELRLAARKSLDRMLEMASGTVGKGDLGRA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TAPIRDSLSGLDLRAEIDRLRKERNAVILAHYYQKPEIQDLADFVGDSLELSRKAAETD
CCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHCH
AEVIAFCGVKFMAETAKILSPEKIVILPDMDAGCSLEDSCPPEQFKRFREKHPDHIALTY
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEE
INCSAAVKALSDIIVTSSSAETIISQIPPEQKIIFGPDRHLGGYMNRKFGRDMLLWPGVC
EEHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCHHHCCHHHHHHCCCEEECCCHH
IVHEAFSETELLKLKAQYPGAPVAAHPECPPHIVEHADYVGSTSGILQFAKSFKGDTLIV
HHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCEEEE
ATEPHIIHQMELALPEKTFIGAPGADGNCNCNICPYMALNTMEKLYIALRDLQPRIEMDE
ECCCHHHHHHHHHCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCH
ELRLAARKSLDRMLEMASGTVGKGDLGRA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]