Click here to switch to the map view.

The map label for this gene is map [H]

Identifier: 103485873

GI number: 103485873

Start: 389645

End: 390484

Strand: Direct

Name: map [H]

Synonym: Sala_0378

Alternate gene names: 103485873

Gene position: 389645-390484 (Clockwise)

Preceding gene: 103485872

Following gene: 103485874

Centisome position: 11.65

GC content: 66.07

Gene sequence:

>840_bases
ATGTATGATTATGTCACCATAACCGCCGACGATGCGACCGCCCCGGCGCGCGTGCGCGACGGCACGATCAAGCTGCACGA
CGAGGCGGGCTTTGCGGGCATGCGCAAGGCGGGGCGGCTGTCGGCCGAGATCCTCGACGCGCTCGTCCCCTTTGTCCAGC
CGGGGGTGACGACTGCGGCGATCGACGACCTCGTCCGCACAATGATGCTGGAGGGCGGGGGCATTCCCGCGACCTTGGGC
TATCGCGGCTTCACGCACAGCTGCTGCACCAGCATCAACCATGTCGTGTGTCACGGCATTCCCGACGACAAGCCGCTGCG
CGAGGGCGACATCGTCAATGTCGATGTCACCAGCATCGTCGATGGCTGGCACGGCGACACCAGCCGCATGTATCTGGTCG
GCGAAGTGCCGATCAAGGCGCGGCGGCTGGTGGAAGTCACCTATGAATGCCTGATGCTCGGCATCGAGCAGGCGAAGCCG
GGCAACCGCATGGGCGACGTCGCGCATGCGATCCAGACCCACGCCGAACGCCACCGTTATTCGGTCGTCCGCGATTTCTG
CGGTCACGGGCTGGGCCAGATGTTCCACGACGCGCCCGAGGTCGTCCACGCCGGGCGCCCCGGCACCGGGCCGGAGCTGC
GCCCCGGCATGTTCTTTACGATCGAGCCGATGATCAACACCGGCAAATATGCGGTAAAGATGCTCGCCGACGGCTGGACC
GCGGTGACGCGCGACCGCTCGCTGTCGGCGCAGTTCGAGCACAGCATCGGGATCACCGAGACGGGTTGCGAGATTTTCAC
CGCGAGCCCGAAGGGTTTGAACGCGCCGCCGTGGGGCTGA

Upstream 100 bases:

>100_bases
CGCGGCGGCGGGAAGCTGGCGGGCGATCGCGCGCGGGCAGCCGCTGGCCGGCTGACGGTCGTGCTCGCAATCCGGTGCGA
CATCGCCTATATCGGTGATC

Downstream 100 bases:

>100_bases
CCGGCACGACGATTCCCATTTCGTCACCCCGGACTTGATCGGGGTCCAGGAAGGCTGGCGCTGCGTTGGAAGTCATGGAT
CCCGGATCAAGTCCGGGATG

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MYDYVTITADDATAPARVRDGTIKLHDEAGFAGMRKAGRLSAEILDALVPFVQPGVTTAAIDDLVRTMMLEGGGIPATLG
YRGFTHSCCTSINHVVCHGIPDDKPLREGDIVNVDVTSIVDGWHGDTSRMYLVGEVPIKARRLVEVTYECLMLGIEQAKP
GNRMGDVAHAIQTHAERHRYSVVRDFCGHGLGQMFHDAPEVVHAGRPGTGPELRPGMFFTIEPMINTGKYAVKMLADGWT
AVTRDRSLSAQFEHSIGITETGCEIFTASPKGLNAPPWG

Sequences:

>Translated_279_residues
MYDYVTITADDATAPARVRDGTIKLHDEAGFAGMRKAGRLSAEILDALVPFVQPGVTTAAIDDLVRTMMLEGGGIPATLG
YRGFTHSCCTSINHVVCHGIPDDKPLREGDIVNVDVTSIVDGWHGDTSRMYLVGEVPIKARRLVEVTYECLMLGIEQAKP
GNRMGDVAHAIQTHAERHRYSVVRDFCGHGLGQMFHDAPEVVHAGRPGTGPELRPGMFFTIEPMINTGKYAVKMLADGWT
AVTRDRSLSAQFEHSIGITETGCEIFTASPKGLNAPPWG
>Mature_279_residues
MYDYVTITADDATAPARVRDGTIKLHDEAGFAGMRKAGRLSAEILDALVPFVQPGVTTAAIDDLVRTMMLEGGGIPATLG
YRGFTHSCCTSINHVVCHGIPDDKPLREGDIVNVDVTSIVDGWHGDTSRMYLVGEVPIKARRLVEVTYECLMLGIEQAKP
GNRMGDVAHAIQTHAERHRYSVVRDFCGHGLGQMFHDAPEVVHAGRPGTGPELRPGMFFTIEPMINTGKYAVKMLADGWT
AVTRDRSLSAQFEHSIGITETGCEIFTASPKGLNAPPWG

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=245, Percent_Identity=48.5714285714286, Blast_Score=244, Evalue=4e-65,
Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=38.9558232931727, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI1786364, Length=236, Percent_Identity=50.8474576271186, Blast_Score=253, Evalue=9e-69,
Organism=Caenorhabditis elegans, GI71996291, Length=246, Percent_Identity=44.7154471544715, Blast_Score=215, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6323273, Length=254, Percent_Identity=42.1259842519685, Blast_Score=220, Evalue=2e-58,
Organism=Drosophila melanogaster, GI21355531, Length=276, Percent_Identity=42.7536231884058, Blast_Score=230, Evalue=9e-61,
Organism=Drosophila melanogaster, GI24583427, Length=247, Percent_Identity=41.7004048582996, Blast_Score=201, Evalue=6e-52,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 30245; Mature: 30245

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDYVTITADDATAPARVRDGTIKLHDEAGFAGMRKAGRLSAEILDALVPFVQPGVTTAA
CCEEEEEEECCCCCCCEECCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHCCCCHHHH
IDDLVRTMMLEGGGIPATLGYRGFTHSCCTSINHVVCHGIPDDKPLREGDIVNVDVTSIV
HHHHHHHHHHCCCCCCEECCCCCCHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEHHHHH
DGWHGDTSRMYLVGEVPIKARRLVEVTYECLMLGIEQAKPGNRMGDVAHAIQTHAERHRY
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
SVVRDFCGHGLGQMFHDAPEVVHAGRPGTGPELRPGMFFTIEPMINTGKYAVKMLADGWT
HHHHHHHCCCHHHHHHCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHEEHHHHCCCE
AVTRDRSLSAQFEHSIGITETGCEIFTASPKGLNAPPWG
EEECCCCCCHHHHHCCCCCCCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MYDYVTITADDATAPARVRDGTIKLHDEAGFAGMRKAGRLSAEILDALVPFVQPGVTTAA
CCEEEEEEECCCCCCCEECCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHCCCCHHHH
IDDLVRTMMLEGGGIPATLGYRGFTHSCCTSINHVVCHGIPDDKPLREGDIVNVDVTSIV
HHHHHHHHHHCCCCCCEECCCCCCHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEHHHHH
DGWHGDTSRMYLVGEVPIKARRLVEVTYECLMLGIEQAKPGNRMGDVAHAIQTHAERHRY
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
SVVRDFCGHGLGQMFHDAPEVVHAGRPGTGPELRPGMFFTIEPMINTGKYAVKMLADGWT
HHHHHHHCCCHHHHHHCCHHHHCCCCCCCCCCCCCCEEEEEECCCCCCHHEEHHHHCCCE
AVTRDRSLSAQFEHSIGITETGCEIFTASPKGLNAPPWG
EEECCCCCCHHHHHCCCCCCCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]