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The map label for this gene is qorA [H]

Identifier: 103485859

GI number: 103485859

Start: 375523

End: 376521

Strand: Direct

Name: qorA [H]

Synonym: Sala_0364

Alternate gene names: 103485859

Gene position: 375523-376521 (Clockwise)

Preceding gene: 103485857

Following gene: 103485861

Centisome position: 11.23

GC content: 68.97

Gene sequence:

>999_bases
GTGACCAGCCTGCCAGCAGACATGACTGCCGTCGCCATCGGCGCGCCGGGGGGACCGGAGATGTTGCAGTCCGTGACGCG
GCCGGTGCCGCAGCCCGGTGCCGAAGAGGTGCTGATCCGCGTCGCCGCGGCAGGGGTCAACCGCCCCGACGTGCTGCAGC
GCATGGGCCTGTATCCGCCGCCGCCGGGCGCGTCGGACCTGCCGGGGCTTGAGGTCGCGGGCACAGTCGTGGCGGTCGGA
CCGGGGGGCGATCCCGAAATGCTGGGACAGGAGGTGTGCGCGCTCGTCGCCGGCGGCGGCTATGCCGAATATTGCACGGC
GCCGGTAGGAAGCTGTTTGCCCGTGCCGAAGGGCTTTTCGATGGCCGAGGCCGCGGCGCTGCCCGAAACCGTCTTTACCG
TGTGGCACAATCTGTTCGAGCGCGGCTATGTGCAGGAGGGTGAGACGGTGCTGGTCCACGGTGGCACGAGCGGTATCGGC
ACGACCGCGATCGGCCTTTGCAAGCTGTTCGGCATCAGGGTGATCGTGACCTGTGGCAGCGCCGACAAATGCGACGCGGC
GCGCGCCCTGGGCGCCGACCTCGCCGTCGATTATTCGAACGAGGATTATGTCGCGGCGGTGAAGGATTTTACCGGCGGGG
CGGGGGTCCATGTCGTGCTCGACATGGTCGGCGGCGATTATGTGCCGCGCAATCTCGACTGCCTCGCCGACGACGGCCGC
CACGTGTCCATCGCCTTCCAGCGCGGTGCCAAGGTCGAGATCGACGTTTCGCAGGTGATGCGCCGCCGCCTGACGCTGAC
CGGATCGACGTTGCGCGCCCGCAGCGCAGCCTTCAAGGCGCTGCTCGCCGACGAGATCCACCGCACGCTTTGGCCGCGCC
TAGCCGAAGGTGCGTGGAAGCCGGCGATGGATCAGGCCTTTGCCCTGACCGACGCCGCCGCCGCCCACGCGCGGATGCAG
GCGGGCGCGCACGTCGGCAAGATCGTGCTGACCGTTTAA

Upstream 100 bases:

>100_bases
GCCATCCTCCTGAAATGACGCGCGACTGTTGACCCGTGTCGCCGCACTGTCAATAAGGCGCGGCAGGGCGTAGGAAACCG
GACCAGTGGGGGAATAAAGC

Downstream 100 bases:

>100_bases
CCCGGCGCGTCGGCGAGCGCGGGCGGGGCTGACGTGGCTGTCGGTAGTCGGCCGACGCCCTCAGGCGGGTTCGAGAGTCC
GTGGTTCGAGGATCAGGCGG

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTSLPADMTAVAIGAPGGPEMLQSVTRPVPQPGAEEVLIRVAAAGVNRPDVLQRMGLYPPPPGASDLPGLEVAGTVVAVG
PGGDPEMLGQEVCALVAGGGYAEYCTAPVGSCLPVPKGFSMAEAAALPETVFTVWHNLFERGYVQEGETVLVHGGTSGIG
TTAIGLCKLFGIRVIVTCGSADKCDAARALGADLAVDYSNEDYVAAVKDFTGGAGVHVVLDMVGGDYVPRNLDCLADDGR
HVSIAFQRGAKVEIDVSQVMRRRLTLTGSTLRARSAAFKALLADEIHRTLWPRLAEGAWKPAMDQAFALTDAAAAHARMQ
AGAHVGKIVLTV

Sequences:

>Translated_332_residues
MTSLPADMTAVAIGAPGGPEMLQSVTRPVPQPGAEEVLIRVAAAGVNRPDVLQRMGLYPPPPGASDLPGLEVAGTVVAVG
PGGDPEMLGQEVCALVAGGGYAEYCTAPVGSCLPVPKGFSMAEAAALPETVFTVWHNLFERGYVQEGETVLVHGGTSGIG
TTAIGLCKLFGIRVIVTCGSADKCDAARALGADLAVDYSNEDYVAAVKDFTGGAGVHVVLDMVGGDYVPRNLDCLADDGR
HVSIAFQRGAKVEIDVSQVMRRRLTLTGSTLRARSAAFKALLADEIHRTLWPRLAEGAWKPAMDQAFALTDAAAAHARMQ
AGAHVGKIVLTV
>Mature_331_residues
TSLPADMTAVAIGAPGGPEMLQSVTRPVPQPGAEEVLIRVAAAGVNRPDVLQRMGLYPPPPGASDLPGLEVAGTVVAVGP
GGDPEMLGQEVCALVAGGGYAEYCTAPVGSCLPVPKGFSMAEAAALPETVFTVWHNLFERGYVQEGETVLVHGGTSGIGT
TAIGLCKLFGIRVIVTCGSADKCDAARALGADLAVDYSNEDYVAAVKDFTGGAGVHVVLDMVGGDYVPRNLDCLADDGRH
VSIAFQRGAKVEIDVSQVMRRRLTLTGSTLRARSAAFKALLADEIHRTLWPRLAEGAWKPAMDQAFALTDAAAAHARMQA
GAHVGKIVLTV

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=40.3030303030303, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=40.3030303030303, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI194239674, Length=327, Percent_Identity=28.7461773700306, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI13236495, Length=327, Percent_Identity=28.7461773700306, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI18379349, Length=323, Percent_Identity=29.4117647058824, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI24308257, Length=343, Percent_Identity=28.8629737609329, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI194239676, Length=203, Percent_Identity=31.5270935960591, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI28557745, Length=245, Percent_Identity=32.6530612244898, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI41872631, Length=322, Percent_Identity=28.2608695652174, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI197927207, Length=196, Percent_Identity=25, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI47519420, Length=246, Percent_Identity=29.6747967479675, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790485, Length=326, Percent_Identity=32.2085889570552, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17507255, Length=329, Percent_Identity=28.2674772036474, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI212642053, Length=318, Percent_Identity=24.5283018867925, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17536829, Length=218, Percent_Identity=27.9816513761468, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=337, Percent_Identity=27.299703264095, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=309, Percent_Identity=25.5663430420712, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=284, Percent_Identity=26.4084507042254, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=356, Percent_Identity=24.7191011235955, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581345, Length=284, Percent_Identity=27.4647887323944, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI221330659, Length=284, Percent_Identity=26.4084507042254, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920632, Length=284, Percent_Identity=26.4084507042254, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34384; Mature: 34253

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLPADMTAVAIGAPGGPEMLQSVTRPVPQPGAEEVLIRVAAAGVNRPDVLQRMGLYPP
CCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCC
PPGASDLPGLEVAGTVVAVGPGGDPEMLGQEVCALVAGGGYAEYCTAPVGSCLPVPKGFS
CCCCCCCCCCEECCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCC
MAEAAALPETVFTVWHNLFERGYVQEGETVLVHGGTSGIGTTAIGLCKLFGIRVIVTCGS
HHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCEEEEEEECC
ADKCDAARALGADLAVDYSNEDYVAAVKDFTGGAGVHVVLDMVGGDYVPRNLDCLADDGR
CCCHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCEECCCCC
HVSIAFQRGAKVEIDVSQVMRRRLTLTGSTLRARSAAFKALLADEIHRTLWPRLAEGAWK
EEEEEEECCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAMDQAFALTDAAAAHARMQAGAHVGKIVLTV
CHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure 
TSLPADMTAVAIGAPGGPEMLQSVTRPVPQPGAEEVLIRVAAAGVNRPDVLQRMGLYPP
CCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCC
PPGASDLPGLEVAGTVVAVGPGGDPEMLGQEVCALVAGGGYAEYCTAPVGSCLPVPKGFS
CCCCCCCCCCEECCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCC
MAEAAALPETVFTVWHNLFERGYVQEGETVLVHGGTSGIGTTAIGLCKLFGIRVIVTCGS
HHHHHHCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCEEEEEEECC
ADKCDAARALGADLAVDYSNEDYVAAVKDFTGGAGVHVVLDMVGGDYVPRNLDCLADDGR
CCCHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCEECCCCC
HVSIAFQRGAKVEIDVSQVMRRRLTLTGSTLRARSAAFKALLADEIHRTLWPRLAEGAWK
EEEEEEECCCEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAMDQAFALTDAAAAHARMQAGAHVGKIVLTV
CHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]