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The map label for this gene is blaI [H]

Identifier: 103485854

GI number: 103485854

Start: 371373

End: 371741

Strand: Direct

Name: blaI [H]

Synonym: Sala_0359

Alternate gene names: 103485854

Gene position: 371373-371741 (Clockwise)

Preceding gene: 103485852

Following gene: 103485855

Centisome position: 11.1

GC content: 67.21

Gene sequence:

>369_bases
ATGGCAGAACGAGCAAGCGAATCGGAGATGCAGGTGCTGTCGGCGCTGTGGGATGAAGCCCCGCAGACCGCCGCCGACCT
GACCCGGCGCGTCGGTGCGGCGAACGGCTGGACGCAGGCGACGGTCAAGACGCTGCTTGCACGGCTGGTGCAGAAGGGCG
CGGTAACCGCCGAGGCCGATGGCCGCCGCTATCTTTACAGCCCCGCGATCGGGCGCGCCGAAGCCGTCGGTGAGGAATCG
CAGCGTTTCGTCGACCGCCTGTTCGGCGGCCGCGTCAGCCCGCTGATCGCACACCTCGCCGATCGTGAGGCGCTGAGCGA
TGCCGACATCGCCGAGATCGAGGCGCTTTTGAAGAAGCTCAAGTCATGA

Upstream 100 bases:

>100_bases
CGGCGACGGGCGGGATCGCCCGTTCGTTCAGCCAGCGTTCAGCCCATTGACTACAACTGTAGTCGCGTCAGTATCGACGA
AGCCAATGGGAGGGGTCCGC

Downstream 100 bases:

>100_bases
GCGCCGCGATGTTTATCGAAGCGTGGAGCGACACGCTGCTCACGACTGCGCTGCTCGTCGTCGCGGTGTTGCTGATCCGC
AAGCCCTTTGCCCGTCATTT

Product: CopY family transcriptional regulator

Products: NA

Alternate protein names: Beta-lactamase repressor protein; Regulatory protein BlaI [H]

Number of amino acids: Translated: 122; Mature: 121

Protein sequence:

>122_residues
MAERASESEMQVLSALWDEAPQTAADLTRRVGAANGWTQATVKTLLARLVQKGAVTAEADGRRYLYSPAIGRAEAVGEES
QRFVDRLFGGRVSPLIAHLADREALSDADIAEIEALLKKLKS

Sequences:

>Translated_122_residues
MAERASESEMQVLSALWDEAPQTAADLTRRVGAANGWTQATVKTLLARLVQKGAVTAEADGRRYLYSPAIGRAEAVGEES
QRFVDRLFGGRVSPLIAHLADREALSDADIAEIEALLKKLKS
>Mature_121_residues
AERASESEMQVLSALWDEAPQTAADLTRRVGAANGWTQATVKTLLARLVQKGAVTAEADGRRYLYSPAIGRAEAVGEESQ
RFVDRLFGGRVSPLIAHLADREALSDADIAEIEALLKKLKS

Specific function: Transcriptional repressor that constitutively blocks expression of beta-lactamase. Regulates genes involved in antibiotic resistance. Binds DNA as a dimer [H]

COG id: COG3682

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BlaI transcriptional regulatory family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005650
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03965 Pencillinase_R [H]

EC number: NA

Molecular weight: Translated: 13195; Mature: 13064

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERASESEMQVLSALWDEAPQTAADLTRRVGAANGWTQATVKTLLARLVQKGAVTAEAD
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
GRRYLYSPAIGRAEAVGEESQRFVDRLFGGRVSPLIAHLADREALSDADIAEIEALLKKL
CCEEECCCCCCHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KS
CC
>Mature Secondary Structure 
AERASESEMQVLSALWDEAPQTAADLTRRVGAANGWTQATVKTLLARLVQKGAVTAEAD
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
GRRYLYSPAIGRAEAVGEESQRFVDRLFGGRVSPLIAHLADREALSDADIAEIEALLKKL
CCEEECCCCCCHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3096969; 3305074; 3260234; 3040663; 3498148 [H]