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The map label for this gene is infC [H]

Identifier: 103485760

GI number: 103485760

Start: 266016

End: 266537

Strand: Direct

Name: infC [H]

Synonym: Sala_0265

Alternate gene names: 103485760

Gene position: 266016-266537 (Clockwise)

Preceding gene: 103485759

Following gene: 103485762

Centisome position: 7.95

GC content: 60.15

Gene sequence:

>522_bases
ATGGCGCCGCTGCCGCCCAAGAACGGCCCGCGATACAATGAATTCATTGCCTCCCCCAAAGTCCGCGTGATCGACGAGGA
AGGCGAAAATCTGGGCGTGATGCTGACGGCCGAAGCGATCGAACAGGCGGCCGAGGTGGGGCTTGACCTTGTCGAAGTGT
CCCCCAATGCCGACCCGCCGGTGTGCAAGTTCCTCGACGTCGGCAAATATAAATATGAGGCGCAGAAAAAGGCGAACCTG
GCCCGCAAGAGCCAGAAGACGCAGGAGATCAAGGAGATCAAGATGCGTCCGAACATCGACGACCATGATTTCGATGTGAA
GATGAAGAAGGTCTTCGACTTCCTCGAGGAAGGCGACAAGGTCAAGATGACCATGCGTTTCCGCGGTCGCGAGATGAGCC
ACACGCAGCTTGGCCTCAACGTGCTCCAGCGCGTCGCCGAGCTGACCGCGGAGGTCGCGAAGGTCGAGGCGCACCCGCGC
ACCGAAGGCCGCCAGATGCTGATGGTGCTGGCGCCGAAATAG

Upstream 100 bases:

>100_bases
CACTATATGATCGTCGGGCGCTCCGCGCGTCGATGCCGCGTGCCCATATCGAAACGAGTGAGGAGATACAGCTATACGCC
CGCCCATGACCCGTCGCCCG

Downstream 100 bases:

>100_bases
GAGCCAGGCGAACCAAGGACCGTCGCCGCCGCGAAGGCGGGGGGCCGCCATCGGTTTATGCAGCACCGCGGGAAAAGGCT
GCCAGCTGCCCCGCCTTCGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MAPLPPKNGPRYNEFIASPKVRVIDEEGENLGVMLTAEAIEQAAEVGLDLVEVSPNADPPVCKFLDVGKYKYEAQKKANL
ARKSQKTQEIKEIKMRPNIDDHDFDVKMKKVFDFLEEGDKVKMTMRFRGREMSHTQLGLNVLQRVAELTAEVAKVEAHPR
TEGRQMLMVLAPK

Sequences:

>Translated_173_residues
MAPLPPKNGPRYNEFIASPKVRVIDEEGENLGVMLTAEAIEQAAEVGLDLVEVSPNADPPVCKFLDVGKYKYEAQKKANL
ARKSQKTQEIKEIKMRPNIDDHDFDVKMKKVFDFLEEGDKVKMTMRFRGREMSHTQLGLNVLQRVAELTAEVAKVEAHPR
TEGRQMLMVLAPK
>Mature_172_residues
APLPPKNGPRYNEFIASPKVRVIDEEGENLGVMLTAEAIEQAAEVGLDLVEVSPNADPPVCKFLDVGKYKYEAQKKANLA
RKSQKTQEIKEIKMRPNIDDHDFDVKMKKVFDFLEEGDKVKMTMRFRGREMSHTQLGLNVLQRVAELTAEVAKVEAHPRT
EGRQMLMVLAPK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=52.4390243902439, Blast_Score=165, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19578; Mature: 19447

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPLPPKNGPRYNEFIASPKVRVIDEEGENLGVMLTAEAIEQAAEVGLDLVEVSPNADPP
CCCCCCCCCCCHHHHHCCCCEEEECCCCCCEEEEEEHHHHHHHHHCCCEEEEECCCCCCC
VCKFLDVGKYKYEAQKKANLARKSQKTQEIKEIKMRPNIDDHDFDVKMKKVFDFLEEGDK
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCE
VKMTMRFRGREMSHTQLGLNVLQRVAELTAEVAKVEAHPRTEGRQMLMVLAPK
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
APLPPKNGPRYNEFIASPKVRVIDEEGENLGVMLTAEAIEQAAEVGLDLVEVSPNADPP
CCCCCCCCCCHHHHHCCCCEEEECCCCCCEEEEEEHHHHHHHHHCCCEEEEECCCCCCC
VCKFLDVGKYKYEAQKKANLARKSQKTQEIKEIKMRPNIDDHDFDVKMKKVFDFLEEGDK
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCE
VKMTMRFRGREMSHTQLGLNVLQRVAELTAEVAKVEAHPRTEGRQMLMVLAPK
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA