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The map label for this gene is yggW [H]

Identifier: 103485753

GI number: 103485753

Start: 259318

End: 260463

Strand: Direct

Name: yggW [H]

Synonym: Sala_0258

Alternate gene names: 103485753

Gene position: 259318-260463 (Clockwise)

Preceding gene: 103485752

Following gene: 103485754

Centisome position: 7.75

GC content: 67.63

Gene sequence:

>1146_bases
ATGTTCGAACCTCTCGCCCTTTATGTTCATTGGCCGTTTTGCGTCAGCAAATGTCCTTATTGTGACTTCAACAGCCATGT
GCGCGACAGCGTCGAACAGGAGGTCTGGCGCGCAGCCCTGCTCGCGGATTTGCGGCATGAGGCGGCGGTGCTGCCTGGGC
GGCGCGTGGCGTCCATCTTTTTCGGTGGCGGGACGCCCAGCCTGATGCCGGCCGCGACGGTGGCGGCGGTGATTGCCGAG
GCAGCCGCGTTGTGGGGACTGACCGACGATTGCGAAATCACGCTCGAAGCGAATCCCAATTCGGCCGAAGTCGCCGCCTT
CGCCGATCTCGCCGCCGCCGGGGTCAACCGCGTGTCGATCGGCGTCCAGAGCTTTGACGCGCAAGCGCTTGCGTTTCTGG
GCCGCGCGCACAGCGAGGATGAGGCGCGGCGAGCGATTGCGATGGCGCAGGAGCATTTTGCGCGCGTCAGTTTCGACCTG
ATCTATGCGCGGCCGGGACAGACGCTGGCAGCATGGGAAGGCGAACTGGCGGACGCGCTGGGCTTCGGCACCGGCCATCT
GTCGCTCTATCAGCTCACCATCGAGCCGGGGACGCGCTTTTGGGCGCTCGCGGCGAAGGGTGAACTCACCATTCCCGATG
GCGACGCCGCGGCCGACCTGTTCGACGCGACGCAGGCGATGACGCGCGCCGCGGGCCTGCCGCGCTACGAAGTGTCGAAC
CACGCGCGACCGGGCGAGGAGAGCCGCCACAATCTCGCCTATTGGCGCTATGCCGATTATGCGGGGGTCGGGCCGGGCGC
GCACGGGCGGCGGCTGCGGCAGGCGACCGAGCGGCACAGGAAACCCGAAAATTTCATCGCCGCGGTGACGCGCAACGGCC
ATGGGCTGAAGGTCGAAACCGACTTGTCCGGCCGCGAGCGCGCGACCGAGGCGATGCTGATGGGGCTGCGGCTGACCGAA
GGCGTCGATCTGGCGCGGGTCGAGGCGCGGAGCGGGTTGCCGCGCGCGGATTTTGTCGATGCCGACGCGGTGGCGCGGCT
TGCCGGGCAGGGGCTGCTGGTCGCGGACGGAGACCGGCTGGCAGTGACCGGGGCGGGGATTTTGCTGCTCGACTCGATCC
TTTCCGAGGTGGTCGAAACTCGGTAG

Upstream 100 bases:

>100_bases
CGTTGACGTTTGCCGAGATCGAACCCGCGGAAAAGCACGCGATCAGCCACCGCGCCGATGCGTTCGCGAAACTGGTGGCA
GGGGTGTTCTGACGCCGCCC

Downstream 100 bases:

>100_bases
TCTCCCCGCACCGTTCGTTCCGAGCGAGGTCGAGGGACGCGCGGCATGGCGCCAACATGTCTCGACTTCGCTCGACACGA
ACGGAATTAAAGGGCGGTTT

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MFEPLALYVHWPFCVSKCPYCDFNSHVRDSVEQEVWRAALLADLRHEAAVLPGRRVASIFFGGGTPSLMPAATVAAVIAE
AAALWGLTDDCEITLEANPNSAEVAAFADLAAAGVNRVSIGVQSFDAQALAFLGRAHSEDEARRAIAMAQEHFARVSFDL
IYARPGQTLAAWEGELADALGFGTGHLSLYQLTIEPGTRFWALAAKGELTIPDGDAAADLFDATQAMTRAAGLPRYEVSN
HARPGEESRHNLAYWRYADYAGVGPGAHGRRLRQATERHRKPENFIAAVTRNGHGLKVETDLSGRERATEAMLMGLRLTE
GVDLARVEARSGLPRADFVDADAVARLAGQGLLVADGDRLAVTGAGILLLDSILSEVVETR

Sequences:

>Translated_381_residues
MFEPLALYVHWPFCVSKCPYCDFNSHVRDSVEQEVWRAALLADLRHEAAVLPGRRVASIFFGGGTPSLMPAATVAAVIAE
AAALWGLTDDCEITLEANPNSAEVAAFADLAAAGVNRVSIGVQSFDAQALAFLGRAHSEDEARRAIAMAQEHFARVSFDL
IYARPGQTLAAWEGELADALGFGTGHLSLYQLTIEPGTRFWALAAKGELTIPDGDAAADLFDATQAMTRAAGLPRYEVSN
HARPGEESRHNLAYWRYADYAGVGPGAHGRRLRQATERHRKPENFIAAVTRNGHGLKVETDLSGRERATEAMLMGLRLTE
GVDLARVEARSGLPRADFVDADAVARLAGQGLLVADGDRLAVTGAGILLLDSILSEVVETR
>Mature_381_residues
MFEPLALYVHWPFCVSKCPYCDFNSHVRDSVEQEVWRAALLADLRHEAAVLPGRRVASIFFGGGTPSLMPAATVAAVIAE
AAALWGLTDDCEITLEANPNSAEVAAFADLAAAGVNRVSIGVQSFDAQALAFLGRAHSEDEARRAIAMAQEHFARVSFDL
IYARPGQTLAAWEGELADALGFGTGHLSLYQLTIEPGTRFWALAAKGELTIPDGDAAADLFDATQAMTRAAGLPRYEVSN
HARPGEESRHNLAYWRYADYAGVGPGAHGRRLRQATERHRKPENFIAAVTRNGHGLKVETDLSGRERATEAMLMGLRLTE
GVDLARVEARSGLPRADFVDADAVARLAGQGLLVADGDRLAVTGAGILLLDSILSEVVETR

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=301, Percent_Identity=43.5215946843854, Blast_Score=238, Evalue=5e-63,
Organism=Escherichia coli, GI1789325, Length=380, Percent_Identity=39.2105263157895, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI87082341, Length=390, Percent_Identity=26.1538461538462, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 40931; Mature: 40931

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEPLALYVHWPFCVSKCPYCDFNSHVRDSVEQEVWRAALLADLRHEAAVLPGRRVASIF
CCCCEEEEEECHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
FGGGTPSLMPAATVAAVIAEAAALWGLTDDCEITLEANPNSAEVAAFADLAAAGVNRVSI
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEE
GVQSFDAQALAFLGRAHSEDEARRAIAMAQEHFARVSFDLIYARPGQTLAAWEGELADAL
EHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEECCCCHHHHHH
GFGTGHLSLYQLTIEPGTRFWALAAKGELTIPDGDAAADLFDATQAMTRAAGLPRYEVSN
CCCCCCEEEEEEEECCCCEEEEEEECCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HARPGEESRHNLAYWRYADYAGVGPGAHGRRLRQATERHRKPENFIAAVTRNGHGLKVET
CCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEE
DLSGRERATEAMLMGLRLTEGVDLARVEARSGLPRADFVDADAVARLAGQGLLVADGDRL
CCCCHHHHHHHHHHHHHHCCCCCCEEEHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCEE
AVTGAGILLLDSILSEVVETR
EEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFEPLALYVHWPFCVSKCPYCDFNSHVRDSVEQEVWRAALLADLRHEAAVLPGRRVASIF
CCCCEEEEEECHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
FGGGTPSLMPAATVAAVIAEAAALWGLTDDCEITLEANPNSAEVAAFADLAAAGVNRVSI
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEE
GVQSFDAQALAFLGRAHSEDEARRAIAMAQEHFARVSFDLIYARPGQTLAAWEGELADAL
EHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEECCCCHHHHHH
GFGTGHLSLYQLTIEPGTRFWALAAKGELTIPDGDAAADLFDATQAMTRAAGLPRYEVSN
CCCCCCEEEEEEEECCCCEEEEEEECCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HARPGEESRHNLAYWRYADYAGVGPGAHGRRLRQATERHRKPENFIAAVTRNGHGLKVET
CCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEE
DLSGRERATEAMLMGLRLTEGVDLARVEARSGLPRADFVDADAVARLAGQGLLVADGDRL
CCCCHHHHHHHHHHHHHHCCCCCCEEEHHHCCCCCCCCCCHHHHHHHHCCCEEEECCCEE
AVTGAGILLLDSILSEVVETR
EEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]