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The map label for this gene is argC

Identifier: 99080964

GI number: 99080964

Start: 1208651

End: 1209679

Strand: Direct

Name: argC

Synonym: TM1040_1123

Alternate gene names: 99080964

Gene position: 1208651-1209679 (Clockwise)

Preceding gene: 99080963

Following gene: 99080965

Centisome position: 37.76

GC content: 58.89

Gene sequence:

>1029_bases
ATGACCCATAACGTGGCAATTCTTGGTGCGTCCGGCTATACCGGCGCAGAGCTGATCCGGCTGATTTCTCAGCACCCGAG
CATCACCATCAAAGCCCTCGCAGCCGAGCGCAAGGCAGGCATGGAGATGGCAGATGTATTCCCGCATCTGCGTCATCTTT
CGCTGCCAACCCTTTGCAAAATAGACGAAATCGACTTCGCACAGATCGATCTGTGTTTCTGTGCTCTGCCGCATAAGACC
AGCCAAGAGGTGATCGCGAAACTGCCGGGTGATCTGAAAATCGTGGATCTGTCGGCGGACTTCCGGCTGCGCGACCCGGA
GGCCTATGAAAAATGGTACGGCAACCCGCATGCGGCGCTCGAGCAGCAGCAGGAGGCGGTCTATGGTCTCACCGAATTTT
ATCGCGATGAGATTAAGGGCGCGCGGCTGGTGGCGGGCACGGGCTGCAATGCGGCCACCGGGCAGTTTGCGCTGCGGCCG
CTGATCGCGGCGGGTGTGATCGACCTTGATGAGATCATCCTCGATATGAAATGTGCGGTCTCCGGCGCCGGGCGGGCGCT
CAAGGAAAACCTGCTGCATGCGGAGCTGAGCGAAGGCTATAACGCCTATGCCATTGGTGGCACCCACCGGCATATCGGCG
AGTTCGATCAGGAGTTCTCGGCTATCGCTGGGCGGCCCGTGAAGGTCCAGTTCACCCCGCATCTGCTGCCGGTGAACCGG
GGGATCCTTGCGACCACCTACGTCAAAGGCGATGCTCAGGCGATCTATGAGACATTTGCCAAGGCCTATGCCGATGAGCC
CTTTGTCGAGCTGCTGCCTTTTGGCGAGGCGCCTTCCACCCATCATGTGCGCGGGTCAAACTTTGTACATATCGGGGTCA
CTGCCGATCGCATCGCAGGGCGCGCAATTGTTATCGTGGCGTTGGATAACCTGACAAAAGGTAGCAGCGGTCAGGCCTTG
CAGAATGCAAACCTGATGTTAGGTGAGGACGAGACAGCCGGGCTGATGATGGCACCGCTGTTCCCCTGA

Upstream 100 bases:

>100_bases
TTTTGAAGCGGCCTGAGGGATTATACCCTCGCGCCCAACCTGATGTCCTGCCTGCGCTCTTTGCAGGCCCCCTTCATATC
TGAACATTCGAGGTCTCGAC

Downstream 100 bases:

>100_bases
ACATCAAGAGGTCCAGATGAAGTCCCTGAAGAAGCAGCGGCGTATCCAGATCATAGCGCTTGCCACCGTGGCCCTTGTTG
GGTCCACGGCGCTCATTGGC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTHNVAILGASGYTGAELIRLISQHPSITIKALAAERKAGMEMADVFPHLRHLSLPTLCKIDEIDFAQIDLCFCALPHKT
SQEVIAKLPGDLKIVDLSADFRLRDPEAYEKWYGNPHAALEQQQEAVYGLTEFYRDEIKGARLVAGTGCNAATGQFALRP
LIAAGVIDLDEIILDMKCAVSGAGRALKENLLHAELSEGYNAYAIGGTHRHIGEFDQEFSAIAGRPVKVQFTPHLLPVNR
GILATTYVKGDAQAIYETFAKAYADEPFVELLPFGEAPSTHHVRGSNFVHIGVTADRIAGRAIVIVALDNLTKGSSGQAL
QNANLMLGEDETAGLMMAPLFP

Sequences:

>Translated_342_residues
MTHNVAILGASGYTGAELIRLISQHPSITIKALAAERKAGMEMADVFPHLRHLSLPTLCKIDEIDFAQIDLCFCALPHKT
SQEVIAKLPGDLKIVDLSADFRLRDPEAYEKWYGNPHAALEQQQEAVYGLTEFYRDEIKGARLVAGTGCNAATGQFALRP
LIAAGVIDLDEIILDMKCAVSGAGRALKENLLHAELSEGYNAYAIGGTHRHIGEFDQEFSAIAGRPVKVQFTPHLLPVNR
GILATTYVKGDAQAIYETFAKAYADEPFVELLPFGEAPSTHHVRGSNFVHIGVTADRIAGRAIVIVALDNLTKGSSGQAL
QNANLMLGEDETAGLMMAPLFP
>Mature_341_residues
THNVAILGASGYTGAELIRLISQHPSITIKALAAERKAGMEMADVFPHLRHLSLPTLCKIDEIDFAQIDLCFCALPHKTS
QEVIAKLPGDLKIVDLSADFRLRDPEAYEKWYGNPHAALEQQQEAVYGLTEFYRDEIKGARLVAGTGCNAATGQFALRPL
IAAGVIDLDEIILDMKCAVSGAGRALKENLLHAELSEGYNAYAIGGTHRHIGEFDQEFSAIAGRPVKVQFTPHLLPVNRG
ILATTYVKGDAQAIYETFAKAYADEPFVELLPFGEAPSTHHVRGSNFVHIGVTADRIAGRAIVIVALDNLTKGSSGQALQ
NANLMLGEDETAGLMMAPLFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=346, Percent_Identity=35.2601156069364, Blast_Score=158, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6320913, Length=360, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_SILST (Q1GHL0)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_613118.1
- ProteinModelPortal:   Q1GHL0
- SMR:   Q1GHL0
- STRING:   Q1GHL0
- GeneID:   4077244
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_1123
- NMPDR:   fig|292414.1.peg.3742
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- PhylomeDB:   Q1GHL0
- ProtClustDB:   PRK00436
- BioCyc:   SSP292414:TM1040_1123-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 36987; Mature: 36856

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHNVAILGASGYTGAELIRLISQHPSITIKALAAERKAGMEMADVFPHLRHLSLPTLCK
CCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEHHHHHCCCCHHHHHHHHHHCCCCCEEE
IDEIDFAQIDLCFCALPHKTSQEVIAKLPGDLKIVDLSADFRLRDPEAYEKWYGNPHAAL
ECCCCHHEEEEEEEECCCCCHHHHHHHCCCCEEEEEECCCCEECCCHHHHHHCCCCHHHH
EQQQEAVYGLTEFYRDEIKGARLVAGTGCNAATGQFALRPLIAAGVIDLDEIILDMKCAV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHC
SGAGRALKENLLHAELSEGYNAYAIGGTHRHIGEFDQEFSAIAGRPVKVQFTPHLLPVNR
CCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCEEECCC
GILATTYVKGDAQAIYETFAKAYADEPFVELLPFGEAPSTHHVRGSNFVHIGVTADRIAG
CEEEEEEECCCHHHHHHHHHHHHCCCCHHEEEECCCCCCCCEECCCCEEEEECCHHHHCC
RAIVIVALDNLTKGSSGQALQNANLMLGEDETAGLMMAPLFP
CEEEEEEECCCCCCCCCCEEECCCEEECCCCCCCEEECCCCC
>Mature Secondary Structure 
THNVAILGASGYTGAELIRLISQHPSITIKALAAERKAGMEMADVFPHLRHLSLPTLCK
CCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEHHHHHCCCCHHHHHHHHHHCCCCCEEE
IDEIDFAQIDLCFCALPHKTSQEVIAKLPGDLKIVDLSADFRLRDPEAYEKWYGNPHAAL
ECCCCHHEEEEEEEECCCCCHHHHHHHCCCCEEEEEECCCCEECCCHHHHHHCCCCHHHH
EQQQEAVYGLTEFYRDEIKGARLVAGTGCNAATGQFALRPLIAAGVIDLDEIILDMKCAV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHC
SGAGRALKENLLHAELSEGYNAYAIGGTHRHIGEFDQEFSAIAGRPVKVQFTPHLLPVNR
CCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCCEEECCC
GILATTYVKGDAQAIYETFAKAYADEPFVELLPFGEAPSTHHVRGSNFVHIGVTADRIAG
CEEEEEEECCCHHHHHHHHHHHHCCCCHHEEEECCCCCCCCEECCCCEEEEECCHHHHCC
RAIVIVALDNLTKGSSGQALQNANLMLGEDETAGLMMAPLFP
CEEEEEEECCCCCCCCCCEEECCCEEECCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA