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The map label for this gene is murI

Identifier: 99080963

GI number: 99080963

Start: 1207757

End: 1208566

Strand: Direct

Name: murI

Synonym: TM1040_1122

Alternate gene names: 99080963

Gene position: 1207757-1208566 (Clockwise)

Preceding gene: 99080962

Following gene: 99080964

Centisome position: 37.73

GC content: 63.09

Gene sequence:

>810_bases
ATGGCAGTTGGTATTTTTGATTCCGGTCTTGGTGGTCTGACCGTGTTGGATGCGGCGCAAAAGCGCCTGCCGGATGTGGA
TTTCCTGTATTACGGCGACAACAGCCATGCGCCTTACGGCGTGCGCGACGCCGAGGACATCTATGAGCTGACGCATAAGG
CCGTGCATGACATGTGGGATCGCGGCTGCAATCTGGTGATCCTGGCCTGTAATACCGCCTCGGCCGCTGCGCTGCGGCGC
ATGCAGGAGGCCGGCGTGCCAGAGGGCAAGCGGGTGCTTGGCGTCTTTGTGCCGCTGATCGAGGCGCTCACCGAACGCCA
GTGGGGGGACAACTCTCCTCCGCGGGAGGTGGCCGTGAAACATGTGGCGCTGTTTGCGACCCCTGCCACCGTGGCAAGCC
GCGCATTTCAGCGCGAGCTGGCGTTTCGCGCCATCGGCGTCGACGTCGAAGCGCAGGCCTGCGGTGGCGTGGTCGATGCC
ATCGAGGAGGGCGACATGATCCTCGCCGAGGCGCTTGTGAAAAGCCATGTCGATGCGCTGCTGCGCAAGATGCCCCGCCC
CGAGGCGGCGATCCTGGGCTGCACCCATTATCCGTTGATGGAAGACGTCTTTCAAAAGGCGCTGGGGCCCGATGTGCAGG
TCTTCAGCCAGGGCCGTCTGGTTGCCGACAGCCTCGCGCACTATCTCGAGCGTCGTCCCGAGATGATTGGTGGCGGCAAT
GCGGGCTATGTGACCACCGGGAATGCCAACCGCGTCAGCAGCCGCGCGACGCAATTCTTGCGACGAGAAATCACTTTTGA
AGCGGCCTGA

Upstream 100 bases:

>100_bases
GAGCTGTCACCAACACCGCTCAAATCCTATGACTACGGGTTCGAGTTCGAAGAAAAACACCGGGCGTGACGCGCGCCCGC
ACACCCAAAGGCAGTGTGAC

Downstream 100 bases:

>100_bases
GGGATTATACCCTCGCGCCCAACCTGATGTCCTGCCTGCGCTCTTTGCAGGCCCCCTTCATATCTGAACATTCGAGGTCT
CGACATGACCCATAACGTGG

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MAVGIFDSGLGGLTVLDAAQKRLPDVDFLYYGDNSHAPYGVRDAEDIYELTHKAVHDMWDRGCNLVILACNTASAAALRR
MQEAGVPEGKRVLGVFVPLIEALTERQWGDNSPPREVAVKHVALFATPATVASRAFQRELAFRAIGVDVEAQACGGVVDA
IEEGDMILAEALVKSHVDALLRKMPRPEAAILGCTHYPLMEDVFQKALGPDVQVFSQGRLVADSLAHYLERRPEMIGGGN
AGYVTTGNANRVSSRATQFLRREITFEAA

Sequences:

>Translated_269_residues
MAVGIFDSGLGGLTVLDAAQKRLPDVDFLYYGDNSHAPYGVRDAEDIYELTHKAVHDMWDRGCNLVILACNTASAAALRR
MQEAGVPEGKRVLGVFVPLIEALTERQWGDNSPPREVAVKHVALFATPATVASRAFQRELAFRAIGVDVEAQACGGVVDA
IEEGDMILAEALVKSHVDALLRKMPRPEAAILGCTHYPLMEDVFQKALGPDVQVFSQGRLVADSLAHYLERRPEMIGGGN
AGYVTTGNANRVSSRATQFLRREITFEAA
>Mature_268_residues
AVGIFDSGLGGLTVLDAAQKRLPDVDFLYYGDNSHAPYGVRDAEDIYELTHKAVHDMWDRGCNLVILACNTASAAALRRM
QEAGVPEGKRVLGVFVPLIEALTERQWGDNSPPREVAVKHVALFATPATVASRAFQRELAFRAIGVDVEAQACGGVVDAI
EEGDMILAEALVKSHVDALLRKMPRPEAAILGCTHYPLMEDVFQKALGPDVQVFSQGRLVADSLAHYLERRPEMIGGGNA
GYVTTGNANRVSSRATQFLRREITFEAA

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=234, Percent_Identity=32.0512820512821, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_SILST (Q1GHL1)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_613117.1
- ProteinModelPortal:   Q1GHL1
- SMR:   Q1GHL1
- STRING:   Q1GHL1
- GeneID:   4077243
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_1122
- NMPDR:   fig|292414.1.peg.3743
- eggNOG:   COG0796
- HOGENOM:   HBG645102
- OMA:   AILGCTH
- ProtClustDB:   CLSK933660
- BioCyc:   SSP292414:TM1040_1122-MONOMER
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 29178; Mature: 29046

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGIFDSGLGGLTVLDAAQKRLPDVDFLYYGDNSHAPYGVRDAEDIYELTHKAVHDMWD
CEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RGCNLVILACNTASAAALRRMQEAGVPEGKRVLGVFVPLIEALTERQWGDNSPPREVAVK
CCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
HVALFATPATVASRAFQRELAFRAIGVDVEAQACGGVVDAIEEGDMILAEALVKSHVDAL
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHCCCHHHHHHHHHHHHHHH
LRKMPRPEAAILGCTHYPLMEDVFQKALGPDVQVFSQGRLVADSLAHYLERRPEMIGGGN
HHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCEEHHCCCHHHHHHHHHHHHCCCCCCCCC
AGYVTTGNANRVSSRATQFLRREITFEAA
CCEEECCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVGIFDSGLGGLTVLDAAQKRLPDVDFLYYGDNSHAPYGVRDAEDIYELTHKAVHDMWD
EEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RGCNLVILACNTASAAALRRMQEAGVPEGKRVLGVFVPLIEALTERQWGDNSPPREVAVK
CCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
HVALFATPATVASRAFQRELAFRAIGVDVEAQACGGVVDAIEEGDMILAEALVKSHVDAL
HHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHHHCCCHHHHHHHHHHHHHHH
LRKMPRPEAAILGCTHYPLMEDVFQKALGPDVQVFSQGRLVADSLAHYLERRPEMIGGGN
HHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCEEHHCCCHHHHHHHHHHHHCCCCCCCCC
AGYVTTGNANRVSSRATQFLRREITFEAA
CCEEECCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA