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The map label for this gene is argS

Identifier: 99080744

GI number: 99080744

Start: 963640

End: 965382

Strand: Direct

Name: argS

Synonym: TM1040_0903

Alternate gene names: 99080744

Gene position: 963640-965382 (Clockwise)

Preceding gene: 99080743

Following gene: 99080745

Centisome position: 30.1

GC content: 59.04

Gene sequence:

>1743_bases
ATGAACCTCTTTACCGATATCCGTACGCTTGTGATCGACAGTCTTGCGGCCATGACGGCCGAAGGGGCCCTGCCGGAGGG
GCTCGACTTTGCCAATGTCACCGTGGAGCCGCCGCGCGATGCGGCGCATGGGGATATGGCGACCAATGCGGCGATGGTGC
TGGCCAAACCCGCCAAGATGAAGCCGCGCGATATTGCCGAGGCGCTGGCCGCGAAGCTGGCGCAGGACAAGCGCATCACC
TCTGCGGAGGTGGCCGGGCCGGGGTTCCTGAACCTGCGTCTGGATCTGTCGGTCTGGCAGGACGTGCTGGGCAAGGCGCT
CAATGCAGAAGAGGCCTATGGCCGCTCTGACATGGGGCAGGGCAAGCGGGTCAACGTTGAATATGTCTCGGCCAACCCGA
CAGGGCCGCTGCACGTGGGACACACGCGCGGTGCCGTCTTTGGTGATGCGCTGGCGAGCCTTCTGGATTTTGCAGGCTAT
GATGTGACCCGCGAGTATTACATCAACGATGGCGGTGCGCAGGTCGATGTGCTCGCGCGGTCGGCCTATCTGCGCTACCT
CGAGGCCCATGGGCAGAGTGTGGAATTCCCCGATGGCACCTATCCGGGCGAGTACCTCAAGGATGTGGGCGCTGCTTTAA
AGGACAAATTCGGCGATCGTTTTGTCGGCCAGCCCGAAGAGACCTGGCTTGAGGAGGTGCGCAACTTTGCCACCGACATG
ATGATGGATCTGATCCGCGAGGATCTGGCACTTCTGGGCGTGGAGATGGATGTTTTCTATTCGGAAAAATCCCTCTACGG
CACCGGGCGCATCGAAGCGGCGCTGGAAAGCCTGGATGCCAAGGGGCTGATCTATGAAGGCGTGCTGGAGCCGCCGAAGG
GCAAGAAGCCTGACGATTGGGAGCCGCGCATCCAGACCCTGTTCAAATCTACCGAACATGGTGATGACGTGGATCGTCCG
GTGAAGAAATCCGATGGTGCATGGACCTATTTTGCCCCCGATATCGCCTATCACTATGACAAGGTCAGCCGTGGCTTTGA
CATGTTGATCGACATCTTTGGGGCTGACCATGGTGGCTATGTCAAACGGATGAAGGCGGCCGTGTCGGCGCTCTCGGATG
GCAAGGTGCCGCTGGATGTCAAGCTCTGCCAGTTGGTGAAGCTTTTCAAGGACGGGCAGGAATTCAAGATGTCCAAGCGG
GCAGGAACCTTTGTGACCCTGCGCGACGTGGTGGATGCGGTGGGCGCAGATGTGACCCGCTTCATGCTGCTGACCCGCAA
GAACGATCAGGGGTTCGATTTTGACCTTGATAAGGCGCTGGAGCAGTCCAAGGACAATCCGGTGTTTTATGTACAATATG
CCAATGCGCGCATCCACTCGACCCTGCGCAAGGCGCGCGAGGCGGGGATCGCTTGTGATGAGGCGACGCTGAGTGGTGCG
GACCTGAGCCTGCTCACACATGACGCACAGCTTGCGGTTGCGCGGAAAGTCGCCGAATGGCCGCGCCAGGTGGAGATCGC
CGCGCGCACCAATGAGCCGCATCGGATCGCCTTTTTCCTCTATGAGTTGGCGTCAGATCTGCATGGTTTGTACCACCTCG
GCAAATCTGAAGAAAGTTTACGATTTGTTAACGAGAGCAGCGAATTGGCAACACATGCCAATTTGGCGCTGGCGCGGGCT
GTTTCGATTGTCATTTCTGCCGGTCTTGGTATTCTTGGCGTCAAACCGGCGCAGGAGATGTGA

Upstream 100 bases:

>100_bases
GGTGCGGTCGCGTGGCCTTTGGGGCGCGTAGGGCTTAGGCGGTTGACCCTGAGCGCGCCCCTCGGTATCCGCTGTGGCTG
ATACCTATGGGACGCCAGAT

Downstream 100 bases:

>100_bases
CACTAAAGTCGCCCGAACCGCCGGTCCGAGGCAGATCAAGAGACCCTACGTGCAGATGTCCCGCCCTGAATTGGGCGGGC
TGTCTGGCACAAATGGGCAG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MNLFTDIRTLVIDSLAAMTAEGALPEGLDFANVTVEPPRDAAHGDMATNAAMVLAKPAKMKPRDIAEALAAKLAQDKRIT
SAEVAGPGFLNLRLDLSVWQDVLGKALNAEEAYGRSDMGQGKRVNVEYVSANPTGPLHVGHTRGAVFGDALASLLDFAGY
DVTREYYINDGGAQVDVLARSAYLRYLEAHGQSVEFPDGTYPGEYLKDVGAALKDKFGDRFVGQPEETWLEEVRNFATDM
MMDLIREDLALLGVEMDVFYSEKSLYGTGRIEAALESLDAKGLIYEGVLEPPKGKKPDDWEPRIQTLFKSTEHGDDVDRP
VKKSDGAWTYFAPDIAYHYDKVSRGFDMLIDIFGADHGGYVKRMKAAVSALSDGKVPLDVKLCQLVKLFKDGQEFKMSKR
AGTFVTLRDVVDAVGADVTRFMLLTRKNDQGFDFDLDKALEQSKDNPVFYVQYANARIHSTLRKAREAGIACDEATLSGA
DLSLLTHDAQLAVARKVAEWPRQVEIAARTNEPHRIAFFLYELASDLHGLYHLGKSEESLRFVNESSELATHANLALARA
VSIVISAGLGILGVKPAQEM

Sequences:

>Translated_580_residues
MNLFTDIRTLVIDSLAAMTAEGALPEGLDFANVTVEPPRDAAHGDMATNAAMVLAKPAKMKPRDIAEALAAKLAQDKRIT
SAEVAGPGFLNLRLDLSVWQDVLGKALNAEEAYGRSDMGQGKRVNVEYVSANPTGPLHVGHTRGAVFGDALASLLDFAGY
DVTREYYINDGGAQVDVLARSAYLRYLEAHGQSVEFPDGTYPGEYLKDVGAALKDKFGDRFVGQPEETWLEEVRNFATDM
MMDLIREDLALLGVEMDVFYSEKSLYGTGRIEAALESLDAKGLIYEGVLEPPKGKKPDDWEPRIQTLFKSTEHGDDVDRP
VKKSDGAWTYFAPDIAYHYDKVSRGFDMLIDIFGADHGGYVKRMKAAVSALSDGKVPLDVKLCQLVKLFKDGQEFKMSKR
AGTFVTLRDVVDAVGADVTRFMLLTRKNDQGFDFDLDKALEQSKDNPVFYVQYANARIHSTLRKAREAGIACDEATLSGA
DLSLLTHDAQLAVARKVAEWPRQVEIAARTNEPHRIAFFLYELASDLHGLYHLGKSEESLRFVNESSELATHANLALARA
VSIVISAGLGILGVKPAQEM
>Mature_580_residues
MNLFTDIRTLVIDSLAAMTAEGALPEGLDFANVTVEPPRDAAHGDMATNAAMVLAKPAKMKPRDIAEALAAKLAQDKRIT
SAEVAGPGFLNLRLDLSVWQDVLGKALNAEEAYGRSDMGQGKRVNVEYVSANPTGPLHVGHTRGAVFGDALASLLDFAGY
DVTREYYINDGGAQVDVLARSAYLRYLEAHGQSVEFPDGTYPGEYLKDVGAALKDKFGDRFVGQPEETWLEEVRNFATDM
MMDLIREDLALLGVEMDVFYSEKSLYGTGRIEAALESLDAKGLIYEGVLEPPKGKKPDDWEPRIQTLFKSTEHGDDVDRP
VKKSDGAWTYFAPDIAYHYDKVSRGFDMLIDIFGADHGGYVKRMKAAVSALSDGKVPLDVKLCQLVKLFKDGQEFKMSKR
AGTFVTLRDVVDAVGADVTRFMLLTRKNDQGFDFDLDKALEQSKDNPVFYVQYANARIHSTLRKAREAGIACDEATLSGA
DLSLLTHDAQLAVARKVAEWPRQVEIAARTNEPHRIAFFLYELASDLHGLYHLGKSEESLRFVNESSELATHANLALARA
VSIVISAGLGILGVKPAQEM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=601, Percent_Identity=25.2911813643927, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI1788184, Length=586, Percent_Identity=26.6211604095563, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71985061, Length=620, Percent_Identity=24.8387096774194, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985068, Length=570, Percent_Identity=24.9122807017544, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320548, Length=571, Percent_Identity=25.2189141856392, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI18859963, Length=623, Percent_Identity=24.2375601926164, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571570, Length=508, Percent_Identity=22.8346456692913, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_SILST (Q1GI80)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_612898.1
- ProteinModelPortal:   Q1GI80
- STRING:   Q1GI80
- GeneID:   4076273
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_0903
- NMPDR:   fig|292414.1.peg.2985
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FFAMRSS
- ProtClustDB:   PRK01611
- BioCyc:   SSP292414:TM1040_0903-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63654; Mature: 63654

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFTDIRTLVIDSLAAMTAEGALPEGLDFANVTVEPPRDAAHGDMATNAAMVLAKPAKM
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHCCCEEEEECCCCC
KPRDIAEALAAKLAQDKRITSAEVAGPGFLNLRLDLSVWQDVLGKALNAEEAYGRSDMGQ
CHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEEHHHHHHHHHHHCCCHHHCCCCCCCC
GKRVNVEYVSANPTGPLHVGHTRGAVFGDALASLLDFAGYDVTREYYINDGGAQVDVLAR
CCEEEEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHH
SAYLRYLEAHGQSVEFPDGTYPGEYLKDVGAALKDKFGDRFVGQPEETWLEEVRNFATDM
HHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
MMDLIREDLALLGVEMDVFYSEKSLYGTGRIEAALESLDAKGLIYEGVLEPPKGKKPDDW
HHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCC
EPRIQTLFKSTEHGDDVDRPVKKSDGAWTYFAPDIAYHYDKVSRGFDMLIDIFGADHGGY
CHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCHHHHHHHHCCCCCHH
VKRMKAAVSALSDGKVPLDVKLCQLVKLFKDGQEFKMSKRAGTFVTLRDVVDAVGADVTR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCEEEHHHHHHHHCCHHHH
FMLLTRKNDQGFDFDLDKALEQSKDNPVFYVQYANARIHSTLRKAREAGIACDEATLSGA
HHHEEECCCCCCCCCHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCC
DLSLLTHDAQLAVARKVAEWPRQVEIAARTNEPHRIAFFLYELASDLHGLYHLGKSEESL
CEEEEECHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
RFVNESSELATHANLALARAVSIVISAGLGILGVKPAQEM
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure
MNLFTDIRTLVIDSLAAMTAEGALPEGLDFANVTVEPPRDAAHGDMATNAAMVLAKPAKM
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCHHCCCEEEEECCCCC
KPRDIAEALAAKLAQDKRITSAEVAGPGFLNLRLDLSVWQDVLGKALNAEEAYGRSDMGQ
CHHHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEEHHHHHHHHHHHCCCHHHCCCCCCCC
GKRVNVEYVSANPTGPLHVGHTRGAVFGDALASLLDFAGYDVTREYYINDGGAQVDVLAR
CCEEEEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEHHHHH
SAYLRYLEAHGQSVEFPDGTYPGEYLKDVGAALKDKFGDRFVGQPEETWLEEVRNFATDM
HHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
MMDLIREDLALLGVEMDVFYSEKSLYGTGRIEAALESLDAKGLIYEGVLEPPKGKKPDDW
HHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCCC
EPRIQTLFKSTEHGDDVDRPVKKSDGAWTYFAPDIAYHYDKVSRGFDMLIDIFGADHGGY
CHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHCCHHHHHHHHCCCCCHH
VKRMKAAVSALSDGKVPLDVKLCQLVKLFKDGQEFKMSKRAGTFVTLRDVVDAVGADVTR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCEEEHHHHHHHHCCHHHH
FMLLTRKNDQGFDFDLDKALEQSKDNPVFYVQYANARIHSTLRKAREAGIACDEATLSGA
HHHEEECCCCCCCCCHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCC
DLSLLTHDAQLAVARKVAEWPRQVEIAARTNEPHRIAFFLYELASDLHGLYHLGKSEESL
CEEEEECHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
RFVNESSELATHANLALARAVSIVISAGLGILGVKPAQEM
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA