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The map label for this gene is xlnD [H]

Identifier: 99080737

GI number: 99080737

Start: 956617

End: 957786

Strand: Direct

Name: xlnD [H]

Synonym: TM1040_0896

Alternate gene names: 99080737

Gene position: 956617-957786 (Clockwise)

Preceding gene: 99080736

Following gene: 99080740

Centisome position: 29.89

GC content: 63.76

Gene sequence:

>1170_bases
ATGAAGTTAGATAAACTCAGAGTAACGGTCGTTGGCGCCGGGATTGGCGGTCTGGCTGCGGCCTACCTGTTGCAACGCGC
GGGCGCGCAGGTGACGGTGCTGGAGCAGGCCGAGGAAATCTCCGAGGTTGGCGCGGGCCTGCAGGTGACGCCCAACGGGG
TGGCCGTGATGCGCGCGATGGGGCTCGCAGATGACCTGGCCTGGTGTGCGCAGCGTGCCCGTGCCGTGGTTCTGCGCCAT
CACCGTGAAGGGCGCGAGGTACTGCGGCTCGATCTTGATCAATACGCCCATGACCTGCGCTATTACTTTGTGCATCGTGC
GGATCTCATCACCCTCCTGGCGGATGCGGTGCGCCGGTCAGGTGTTCAAGTGCGTCTGCTGCAAAAAGTGAACGCCGTGG
TGCCGGGCGCACGTCCCAAGGTGCAACTGGCCAATGGCGATACCTGCTGCGCCGATCTGGTGGTCGGGGCCGATGGGCTG
CATTCGCGTGTGCGACCTGCGCTCAATTCCGTGGCAGCGCCAAAATTCACGGGTCAGGTGGCCTGGCGGGCAACAATCCC
CAACCGGCTGGATCTGGCCGCAGAGGCGCAGGTCTTTATGGGGCCTGGGCGGCATCTGGTGGCCTATCCGCTCAAGGATG
GCTCCTTGGTCAATCTTGTCGCGGCACAGGAGCGGCGACAATGGGCAGAAGAAAGCTGGAGCCACGGAGACGATCCCGAG
AACCTGCGTCGGGCGTTTTCCATGTTTGGTGGCGCTGCAGCAGAGCTGCTTGCGGATGTGCGTGACGTCAAGCTCTGGGG
GCTGTTTCGTCATCCGGTGGCGCAAAGCTGGGGCCGCGACGGTGTGGCCTTGCTGGGGGATGCGGCGCATCCGACGCTGC
CCTTTATGGCGCAGGGGGCCAATATGGCGCTCGAGGATGCCTACGCCCTGGTGCAGAGCCTTTTGGGGGCAGAGGGTTTT
GAGGCGGGGCTTTCGGCCTATCAGGCGCGCCGGCACCAGCGGGTGTCAAAGGTGGTTGAGGCGGCAAATGGCAATGCGTG
GAAATACCATCTGCGTTCCCCGCTGAGCTGGCCAGCGCATCAGATCCTGCGAGTAGCCGGGGCGCTGGCACCACAACGGA
TGGTCAGCCAGTTCGATTGGATCTATCGCCACGACGAGACGGCGGTTTGA

Upstream 100 bases:

>100_bases
ACGACTAATTTCAGTCATCCACAAGATTATAAAGCGCCGGGTCTTTTGATCCGGCGCTTTTTTGTTATGAGCTAGTTAAC
GGGGTTCGGGCATTGGGCGC

Downstream 100 bases:

>100_bases
GCGGGTGATCCTGAGCGGTCGAGTTTGACCGGGTTCGGTAAGTCCCTGATAGTTATTTTTTAATGTGCATGTCCATGTAT
GAGGTGTTTCGCTTTGGGCT

Product: monooxygenase, FAD-binding

Products: NA

Alternate protein names: Constitutive 3-hydroxybenzoate 6-hydroxylase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKLDKLRVTVVGAGIGGLAAAYLLQRAGAQVTVLEQAEEISEVGAGLQVTPNGVAVMRAMGLADDLAWCAQRARAVVLRH
HREGREVLRLDLDQYAHDLRYYFVHRADLITLLADAVRRSGVQVRLLQKVNAVVPGARPKVQLANGDTCCADLVVGADGL
HSRVRPALNSVAAPKFTGQVAWRATIPNRLDLAAEAQVFMGPGRHLVAYPLKDGSLVNLVAAQERRQWAEESWSHGDDPE
NLRRAFSMFGGAAAELLADVRDVKLWGLFRHPVAQSWGRDGVALLGDAAHPTLPFMAQGANMALEDAYALVQSLLGAEGF
EAGLSAYQARRHQRVSKVVEAANGNAWKYHLRSPLSWPAHQILRVAGALAPQRMVSQFDWIYRHDETAV

Sequences:

>Translated_389_residues
MKLDKLRVTVVGAGIGGLAAAYLLQRAGAQVTVLEQAEEISEVGAGLQVTPNGVAVMRAMGLADDLAWCAQRARAVVLRH
HREGREVLRLDLDQYAHDLRYYFVHRADLITLLADAVRRSGVQVRLLQKVNAVVPGARPKVQLANGDTCCADLVVGADGL
HSRVRPALNSVAAPKFTGQVAWRATIPNRLDLAAEAQVFMGPGRHLVAYPLKDGSLVNLVAAQERRQWAEESWSHGDDPE
NLRRAFSMFGGAAAELLADVRDVKLWGLFRHPVAQSWGRDGVALLGDAAHPTLPFMAQGANMALEDAYALVQSLLGAEGF
EAGLSAYQARRHQRVSKVVEAANGNAWKYHLRSPLSWPAHQILRVAGALAPQRMVSQFDWIYRHDETAV
>Mature_389_residues
MKLDKLRVTVVGAGIGGLAAAYLLQRAGAQVTVLEQAEEISEVGAGLQVTPNGVAVMRAMGLADDLAWCAQRARAVVLRH
HREGREVLRLDLDQYAHDLRYYFVHRADLITLLADAVRRSGVQVRLLQKVNAVVPGARPKVQLANGDTCCADLVVGADGL
HSRVRPALNSVAAPKFTGQVAWRATIPNRLDLAAEAQVFMGPGRHLVAYPLKDGSLVNLVAAQERRQWAEESWSHGDDPE
NLRRAFSMFGGAAAELLADVRDVKLWGLFRHPVAQSWGRDGVALLGDAAHPTLPFMAQGANMALEDAYALVQSLLGAEGF
EAGLSAYQARRHQRVSKVVEAANGNAWKYHLRSPLSWPAHQILRVAGALAPQRMVSQFDWIYRHDETAV

Specific function: Catalyzes the NAD- or NADP-dependent conversion of 3- hydroxybenzoate to gentisate. The affinity of the enzyme toward NAD is twice as high as for NADP. The enzyme shows higher specific activities against the intermediates in the degradation of 2,5- xyleno

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxybenzoate 6-hydroxylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: =1.14.13.24 [H]

Molecular weight: Translated: 42407; Mature: 42407

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDKLRVTVVGAGIGGLAAAYLLQRAGAQVTVLEQAEEISEVGAGLQVTPNGVAVMRAM
CCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCEECCCHHHHHHHH
GLADDLAWCAQRARAVVLRHHREGREVLRLDLDQYAHDLRYYFVHRADLITLLADAVRRS
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVQVRLLQKVNAVVPGARPKVQLANGDTCCADLVVGADGLHSRVRPALNSVAAPKFTGQV
CCEEEHHHHHHHHCCCCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCE
AWRATIPNRLDLAAEAQVFMGPGRHLVAYPLKDGSLVNLVAAQERRQWAEESWSHGDDPE
EEEEECCCHHCHHHCCCEEECCCCEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCHH
NLRRAFSMFGGAAAELLADVRDVKLWGLFRHPVAQSWGRDGVALLGDAAHPTLPFMAQGA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHCCCC
NMALEDAYALVQSLLGAEGFEAGLSAYQARRHQRVSKVVEAANGNAWKYHLRSPLSWPAH
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHH
QILRVAGALAPQRMVSQFDWIYRHDETAV
HHHHHHHHCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLDKLRVTVVGAGIGGLAAAYLLQRAGAQVTVLEQAEEISEVGAGLQVTPNGVAVMRAM
CCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCCEECCCHHHHHHHH
GLADDLAWCAQRARAVVLRHHREGREVLRLDLDQYAHDLRYYFVHRADLITLLADAVRRS
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVQVRLLQKVNAVVPGARPKVQLANGDTCCADLVVGADGLHSRVRPALNSVAAPKFTGQV
CCEEEHHHHHHHHCCCCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCE
AWRATIPNRLDLAAEAQVFMGPGRHLVAYPLKDGSLVNLVAAQERRQWAEESWSHGDDPE
EEEEECCCHHCHHHCCCEEECCCCEEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCHH
NLRRAFSMFGGAAAELLADVRDVKLWGLFRHPVAQSWGRDGVALLGDAAHPTLPFMAQGA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHCCCC
NMALEDAYALVQSLLGAEGFEAGLSAYQARRHQRVSKVVEAANGNAWKYHLRSPLSWPAH
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHH
QILRVAGALAPQRMVSQFDWIYRHDETAV
HHHHHHHHCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12909360 [H]